Research Faculty Choosing Graduate Training In Biochemistry and ...€¦ · Training graduate...
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The Bridge from Molecules to Life West Virginia University is an Equal Opportunity/Affirmave Acon Instuon Brad Hillgartner, PhD, Graduate Director Room 3088, Health Sciences North Phone: (304) 293-7751 Email: [email protected] Quesons? Where are our graduates? Training graduate students since 1956 Choosing Graduate Training In Biochemistry and Molecular Biology Research Faculty Yehenew Agazie - He studies the Src homology phosphotyrosyl phosphatase 2 (SHP2) in signaling pathways and its role in cancer. Andrey Bobko - He is interested in the developing of new probes and ap- proaches for in vivo mulfunconal spectroscopy and imaging using electron and nuclear magnec resonance techniques. Jianhi Du - Dr. Du’s lab is interested in idenfying new metabolic mechanisms in renal degenerave diseases and developing biochemical approaches for treatment using mass spectrometry, paent stem cell-derived renal cells and animal models. Steve Frisch - The mechanism of anoikis and the development of novel can- cer therapeucs based on this mechanism is a major focus of the laboratory. Brad Hillgartner - He studies the mechanisms mediang the nutrional and hormonal regulaon of genes involved carbohydrate and lipid metabolism. Alexey Ivanov - He studies mechanisms that regulate how the DNA- packaging structure of chroman is regulated during cellular processes. Valery Khramtsov— His lab is devoted to the development and applicaon of new magnec resonance approaches to biomedicine, including EPR spectros- copy and imaging and OMRI or PEDRI. Roberta Leonardi - Her lab studies the role of small metabolites in regulang pathways important for providing energy to cells and controlling glucose homeostasis. Elena Pugacheva - Her lab studies the focal adhesion scaffolding proteins and their role in proliferaon, invasion, and tumor progression. Vishy Ramamurthy - His lab studies the biochemical mechanisms that result in photoreceptor cell death; Protein methylaon; Gene therapy for blinding diseases. Aaron Robart - His lab uses a combinaon of biochemistry and structural biology to understand the architecture and catalyc mechanisms of RNA molecular machines. Mike Ruppert - His lab studies transcripon factors as regulators of chroma- n structure, gene transcripon and malignant transformaon in epithelial cells. Michael Schaller - His lab studies the role of focal adhesion kinases in cellular funcon using techniques of structural biology and cell biology. Richard Seſtor - His lab studies the mechanisms associated with how ag- gressive cancer cells invade and metastasize, and is presently focused on how Nodal, a TGF-beta family member, regulates the aggressive cancer cell phe- notype. David Smith - His lab is studying the workings of the proteasome – a giant molecular machine that uses energy to selecvely destroy proteins. This research aims to idenfy drugs that target the proteasome, which could be useful to treat cancer and various neurodegenerave diseases. Max Sokolov - The lab studies molecular mechanisms of protein homeosta- sis in neurons that require molecular chaperones. Peter Stoilov - Alternave pre-mRNA splicing in cancer progression; Drugs targeng alternave splicing as cancer therapeucs; High-throughput re- search methods. Mark Tseytlin - His lab is developing new spectroscopic and imaging methods for in vivo Electron Paramagnec Resonance (EPR). For more informaon about faculty acvely seeking students for their laboratories, visit our online look book at: hp://medicine.hsc.wvu.edu/biochemistry/research- opportunies/ “The educaon I received (at WVU) prepared me to think crically, independently, and in group sengs. I have used this throughout my career, whether it was as a post doctoral fellow, a research scienst with a pharmaceu- cal consulng firm, or currently, as a clinical scienst with a medical device firm. This solid foundaon will be bene- ficial, no maer what career path is chosen.” Jason Waggoner, Ph.D. , Clinical Scienst, Ethicon “I remember when I went off to my post-doc… I was the “go-to” person (for) molecular biology techniques, and the only one who knew how to fix the equipment! I was trained – not only in state-of-the-art experimentaon, but also very important pragmac issues of running a lab.” Leslie Bruggeman, Ph.D., Associate Professor, Case Western Reserve University “The training that I received at WVU was an invaluable tool for my... professional career in science. My transi- on from Biochemistry to Molecular Immunology… was easy even though I was not a trained immunologist.” Debbie Hodge, Ph.D., Staff Scienst, Naonal Cancer Instute They are postdocs: Harvard, NIH, UC San Diego, Univ. of Cincinna, Univ. of Wis- consin, University of North Carolina, Washington Universoty They are faculty at: University of Pisburgh, University of Michigan They are in industry: Bayer, Pfizer, Protea
Transcript of Research Faculty Choosing Graduate Training In Biochemistry and ...€¦ · Training graduate...
The Bridge from Molecules to Life West Virginia University is an Equal Opportunity/Affirmative Action Institution
Brad Hillgartner, PhD, Graduate Director Room 3088, Health Sciences North
Phone: (304) 293-7751 Email: [email protected]
Questions?
Where are our graduates?
Training graduate students since 1956 Choosing Graduate Training In Biochemistry and Molecular Biology
Research Faculty
Yehenew Agazie - He studies the Src homology phosphotyrosyl phosphatase 2 (SHP2) in signaling pathways and its role in cancer.
Andrey Bobko - He is interested in the developing of new probes and ap-proaches for in vivo multifunctional spectroscopy and imaging using electron and nuclear magnetic resonance techniques.
Jianhi Du - Dr. Du’s lab is interested in identifying new metabolic mechanisms in retinal degenerative diseases and developing biochemical approaches for treatment using mass spectrometry, patient stem cell-derived retinal cells and animal models.
Steve Frisch - The mechanism of anoikis and the development of novel can-cer therapeutics based on this mechanism is a major focus of the laboratory.
Brad Hillgartner - He studies the mechanisms mediating the nutritional and hormonal regulation of genes involved carbohydrate and lipid metabolism.
Alexey Ivanov - He studies mechanisms that regulate how the DNA-packaging structure of chromatin is regulated during cellular processes.
Valery Khramtsov— His lab is devoted to the development and application of new magnetic resonance approaches to biomedicine, including EPR spectros-copy and imaging and OMRI or PEDRI.
Roberta Leonardi - Her lab studies the role of small metabolites in regulating pathways important for providing energy to cells and controlling glucose homeostasis.
Elena Pugacheva - Her lab studies the focal adhesion scaffolding proteins and their role in proliferation, invasion, and tumor progression.
Vishy Ramamurthy - His lab studies the biochemical mechanisms that result in photoreceptor cell death; Protein methylation; Gene therapy for blinding diseases.
Aaron Robart - His lab uses a combination of biochemistry and structural biology to understand the architecture and catalytic mechanisms of RNA molecular machines.
Mike Ruppert - His lab studies transcription factors as regulators of chroma-tin structure, gene transcription and malignant transformation in epithelial cells.
Michael Schaller - His lab studies the role of focal adhesion kinases in cellular function using techniques of structural biology and cell biology.
Richard Seftor - His lab studies the mechanisms associated with how ag-gressive cancer cells invade and metastasize, and is presently focused on how Nodal, a TGF-beta family member, regulates the aggressive cancer cell phe-notype.
David Smith - His lab is studying the workings of the proteasome – a giant molecular machine that uses energy to selectively destroy proteins. This research aims to identify drugs that target the proteasome, which could be useful to treat cancer and various neurodegenerative diseases.
Max Sokolov - The lab studies molecular mechanisms of protein homeosta-sis in neurons that require molecular chaperones.
Peter Stoilov - Alternative pre-mRNA splicing in cancer progression; Drugs targeting alternative splicing as cancer therapeutics; High-throughput re-search methods.
Mark Tseytlin - His lab is developing new spectroscopic and imaging methods for in vivo Electron Paramagnetic Resonance (EPR).
For more information about faculty actively seeking students for their laboratories, visit our online look book at: http://medicine.hsc.wvu.edu/biochemistry/research-opportunities/
“The education I received (at WVU) prepared me to think critically, independently, and in group settings. I have used this throughout my career, whether it was as a post doctoral fellow, a research scientist with a pharmaceuti-cal consulting firm, or currently, as a clinical scientist with a medical device firm. This solid foundation will be bene-ficial, no matter what career path is chosen.” Jason Waggoner, Ph.D. , Clinical Scientist, Ethicon “I remember when I went off to my post-doc… I was the “go-to” person (for) molecular biology techniques, and the only one who knew how to fix the equipment! I was trained – not only in state-of-the-art experimentation, but also very important pragmatic issues of running a lab.” Leslie Bruggeman, Ph.D., Associate Professor, Case Western Reserve University “The training that I received at WVU was an invaluable tool for my... professional career in science. My transi-tion from Biochemistry to Molecular Immunology… was easy even though I was not a trained immunologist.” Debbie Hodge, Ph.D., Staff Scientist, National Cancer Institute
They are postdocs: Harvard, NIH, UC San Diego, Univ. of Cincinnati, Univ. of Wis-consin, University of North Carolina, Washington Universoty
They are faculty at: University of Pittsburgh, University of Michigan
They are in industry: Bayer, Pfizer, Protea
Curriculum Highlights Flexible curriculum to allow time for electives
Advanced courses are literature based
Opportunities for students to invite seminar speakers
Student organized journal club
Qualifying exams: - written – year 2, take-home on topic of student’s choice - oral – year 3, defense of disserta-tion proposal
Opportunities to develop seminar skills
http://medicine.hsc.wvu.edu/biochemistry/education/graduate-program/
Why be a Biochemist?
Studying Biochemistry and Molecular Biology means that you are learning about how mo-lecular events in cells and how the structure and function of molecules regulate the whole organism. It is a field where we ask, “how does that happen?” and not just, “what hap-pens if?” This is a field for individuals with natural curiosity about how life works.
Flexibility for your future career is a key feature of graduate training in Biochemistry and Molecular Biology. The fundamental knowledge and laboratory skills learned in this pro-gram allow easy transitions into the study of multiple scientific disciplines. Biochemical ex-perimentation is integral for the development of new drugs and for obtaining the knowledge that enhances our understanding of disease processes. As a graduate of this program you will be prepared for a career in academics, the pharmaceutical industry, or the government sector.
Opportunities for professional development Attendance of national and international conferences
Developing speaking skills through research talks and seminar presenta-tions.
Developing teaching skills by mentoring undergraduates and giving lec-tures
Obtaining top-notch laboratory skills
Publishing in top tiered journals
Applying for and receiving fellowships
- Zach Hartman - Department of Defense Breast Cancer Fel-lowship
- Aaron Snoberger - National Institute of Health F31 Fellow-ship
Graduate Program in Biochemistry & Molecular Biology http://www.facebook.com/WVUBiochemistry
Biochemistry is the Bridge from Molecules to Life
Graduate research opportunities address important health issues:
Cancer Blindness Deafness Diabetes Obesity Neurodegenerative disease Inflammatory Bowel Disease
Dr. Aaron Robart, Ph.D., one of
our newest faculty members
PhD: University of Calgary,
Postdoctoral Training: University of
California, Berkeley & San Diego
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