Luis Daniel Uribe Montoya

ID: 000094455

The DNA repair allowsthe cells to keep

producing proteins and to replicate themself.

There are genes that notalways are being

expressed and requiresa trigger to start that

process.

MECHANISM REGULATING GENE EXPRESSION LINKED TO BONE AND JOINT DAMAGE IN

ANKYLOSING SPONDYLITIS.Influence of epigenetics on disease progression

(June 12, 2015)

MECHANISM REGULATING GENE EXPRESSION LINKED TO BONE AND JOINT DAMAGE IN ANKYLOSING SPONDYLITIS.

A high metilation state of DNA is related with the non

expression of genes.

MECHANISM REGULATING GENE EXPRESSION LINKED TO BONE AND JOINT DAMAGE IN ANKYLOSING SPONDYLITIS.

MECHANISM REGULATING GENE EXPRESSION LINKED TO BONE AND JOINT DAMAGE IN ANKYLOSING SPONDYLITIS.

The study consisted of 75 AS patients that had radiographs on

average every three years, with 35 of these patients exhibiting radiographic progression.

MECHANISM REGULATING GENE EXPRESSION LINKED TO BONE AND JOINT DAMAGE IN ANKYLOSING SPONDYLITIS.

INVESTIGATING THE

MECHANISMS THAT CONTROL THESE CHANGES COULD ONE DAY

LEAD TO THERAPEUTIC

TARGETS FOR AS.

MECHANISM REGULATING GENE EXPRESSION LINKED TO BONE AND JOINT DAMAGE IN ANKYLOSING SPONDYLITIS.

Student´s Observation:

SCIENTISTS DISCOVER FIRST 'DNA AMBULANCE'(July 24, 2015)

The nuclear pore complex, repairs damaged DNA

inaccurately, which could leads to

develop cancer.

The researchers discovered this DNA

ambulance, which is a motor protein complex,

by using yeast cells.

The researchers team is searching for more DNA ambulances and roads while

conducting a study to see what role

they might play in causing cancer.

THESE ADVANCES WILL LEAD US TO A BETTER

UNDERSTANDING OF THE HUMAN BODY PATOLOGY.

BEING ABLE TO RELATE GENOMIC DAMAGE

WITH THE ADVANCE OF A PATOLOGY WILL

EVENTUALLY GIVE US THE CAPACITY TO

GENERATE NOT ONLY A TREATMENT FOR IT

BUT A CURE.

THE TREATMENTS AREUSUALLY USED WHEN ADISEASE HAVE STARTED TODAMAGE OUR BODY BUT IFDOCTORS CAN BEGIN THEUSE OF MEDICAMENTS TOAVOID THE INITIAL DAMAGEIT WILL BE LIKE THEPHYLOSOPHER´S STONE FOROUR LIFES, GETTING AWAYOF ILLNESS AND AGING.

European League Against Rheumatism. (2015, June 12). Mechanism regulating gene expression linked to bone and joint damage in ankylosing spondylitis: Influence of epigenetics on disease progression. ScienceDaily. Retrieved August 23, 2015 from http://www.sciencedaily.com/releases/2015/06/150612091828.htm

University of Toronto. (2015, July 24). Scientists discover first 'DNA ambulance'. ScienceDaily. Retrieved August 23, 2015 from http://www.sciencedaily.com/releases/2015/07/150724081702.htm

ANGER AND HATE IT'S

JUST A HUMAN

PLAY