Reminder summary....NEW PRODUCT PORTFOLIO CONCEPT RESEARCH AND DIAGNOSTICS MARKET SEGMENTS GLOBAL...
Transcript of Reminder summary....NEW PRODUCT PORTFOLIO CONCEPT RESEARCH AND DIAGNOSTICS MARKET SEGMENTS GLOBAL...
Judit Eszter Illés Head of Marketing
Technical Training
May 18, 2020
The future of 3DHISTECH's product portfolio:
division into
Research (RX) and diagnostics (DX) products.
Reminder summary.
NEW PRODUCT PORTFOLIO CONCEPT
Market backround:• digital pathology market is growing dinamically in RX and DX
Professional background:• the workflow in the RX and DX fields are completely different• the DX workflow in pathology is regulated by strict protocols, rules,
regulations and law
Goal of the company:• to be significant market player also in the DX market
Strategy:• we created two parallel product/system portfolios for the RX and the
DX markets to meet the needs of the professionals in both segments
NEW PRODUCT PORTFOLIO CONCEPTRESEARCH AND DIAGNOSTICS MARKET SEGMENTS
GLOBAL DIGITAL PATHOLOGY MARKET
*Source: Markets&Markets Digital Pathology Market – Forecast for 2022
• According to forecast the market will grow dinamically
• Annual growth estimate ~ 12,3%
• Contains:• Routine diagnostics• Research labs• Molecular pathology• Clinical, pre-clinical trials• Education• etc.
(*)
NEW PRODUCT PORTFOLIO CONCEPTRESEARCH AND DIAGNOSTICS MARKET SEGMENTS
DIGITAL PATHOLOGY MARKET SHARE BY END-USERS 2018 (%)
*Source: www.envisionintelligence.com
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(*)
NEW PRODUCT PORTFOLIO CONCEPTRESEARCH AND DIAGNOSTICS MARKET SEGMENTS
MAIN MARKET DRIVERS
*Source: Markets&Markets Digital Pathology Market – Forecast for 2022
• Continuous and dynamic increase of cancer cases
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NEW PRODUCT PORTFOLIO CONCEPTRESEARCH AND DIAGNOSTICS MARKET SEGMENTS
GLOBAL DIGITAL PATHOLOGY MARKET
MAIN MARKET DRIVERS
• Continuous and dynamic increase of cancer cases
• Increased focus on improving workflow efficiency
• Higher demand for faster diagnostic tools
• Increasing number of governments’ initiatives
• Stricter regulations in the DX segment.
• These accelerated technological advancements of producers ofdigital pathology systems
NEW PRODUCT PORTFOLIO CONCEPTRESEARCH AND DIAGNOSTICS MARKET SEGMENTS
• The market is not matured
• Not a lot of players
• Highly innovative products and complex solutions
• Require sophisticated integration
• Very high investments
GLOBAL DIGITAL PATHOLOGY MARKET
↓
• The winning strategy: being there and having the flexibility to answer market and regulatory needs!
7X
NEW PRODUCT PORTFOLIO CONCEPTRESEARCH AND DIAGNOSTICS MARKET SEGMENTS
COMPANY BACKGROUND
• Digitalisation in pathology first appeared in RESEARCH
• 3DHISTECH also started its developments in this segment~ 25 years ago
• As the first European manufacturer, 3DHISTECH is one of the market leaders in the world with ~ 2.000 sold systems worldwide
• In 2019 the majority of our sales were realized in Research
8X
NEW PRODUCT PORTFOLIO CONCEPTRESEARCH AND DIAGNOSTICS MARKET SEGMENTS
COMPRISON OF PAST AND FUTURE SOLUTIONS
From 2020, 3DHISTECH is committed to meet the needs of users:
RESEARCH market segment DIAGNOSTICS market segment
TWO PARALLEL PRODUCT PORTFOLIOS
TAILORED EXACTLY TO THE NEEDS
OF BOTH RESPECTIVE MARKET SEGMENTS!
9X
NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
DIFFERENCES BETWEEN THE NEEDS OF SEGMENTS – WORKFLOW
LIS »
• Difference in workflows
• Difference in the purposeof the tests(end result)
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NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
DIFFERENCES BETWEEN THE NEEDS OF SEGMENTS – WORKFLOW
DX RX
DIAGNOSIS / CONCEPT on request form: suspected diagnosis concept to verify
SUBJECT case project
IN FOCUS single case (of a patient) slides
HISTORY OF DATA case history, current patient status blind cases, specimen
DATA HANDLING data of patient and doctors must be documented batch data, batch analysis
ADDITIONAL INFORMATION macro images
AREA OF STUDY field of view (FOV) - single field of interest is annotated whole slide imaging, tissue segmentation
TELECONSULTATION images, case description, case history - in closed system
REPORT reporting in a closed system excel output from an open system (raw data)
INTEGRATION NEEDS LIS / PIS / HIS integration (pooled patient data)
IMAGE FORMAT DICOM (PACS) TIFF, JPEG, BIGTIFF
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NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
DIFFERENCES BETWEEN THE NEEDS OF SEGMENTS – WORKFLOW
DX RX
DIAGNOSIS / CONCEPT on request form: suspected diagnosis concept to verify
SUBJECT case project
IN FOCUS single case (of a patient) slides
HISTORY OF DATA case history, current patient status blind cases, specimen
DATA HANDLING data of patient and doctors must be documented batch data, batch analysis
ADDITIONAL INFORMATION macro images
AREA OF STUDY field of view (FOV) - single field of interest is annotated whole slide imaging, tissue segmentation
TELECONSULTATION images, case description, case history - in closed system
REPORT reporting in a closed system excel output from an open system (raw data)
INTEGRATION NEEDS LIS / PIS / HIS integration (pooled patient data)
IMAGE FORMAT DICOM (PACS) TIFF, JPEG, BIGTIFF
IVDR / MDR / FDA
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COMPRISON OF CURRENT AND FUTURE SOLUTIONS
NO CHANGES
• We offered solutions for both market segments also in the past
• Committed to continuous development of our products /solutions
• In our hardware product portfolio
CHANGES
• We adjusted the features of our products/systems to the special needs of the specific segments (RX and DX)
• We created a complex solution especially for DX segment(Pannoramic Pathology Diagnostic System)
NEW PRODUCT PORTFOLIO CONCEPTRESEARCH AND DIAGNOSTICS MARKET SEGMENTS
13X
We offered solutions for each step of the Routine pathology workflow also in the past
Routine pathology
NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
WORKFLOW AND SOLUTIONS - PAST
Quant Center
Image Analysis
Platform
MacroStation
REGISTRATION GROSSING SECTIONING STAINING SLIDE SCANNING SPECIAL ORDERSANALYSIS &
CONSULTATIONREPORTING
Track&Sign Laboratory Information System
PANNORAMIC Digital Slide Scanners
CaseManager Pathology Information System
CaseCenter
CaseViewer
Solutions 3DHISTECH offers for Research labs
NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
Quant Center Image Analysis Platform
CaseViewer
TMA MASTER II and TMA GM PANNORAMIC Digital Slide Scanners CaseCenter
PREPARATIONS SLIDE SCANNING SLIDE STORAGE, VISUALISATION, ANALYSIS
15X
PANNORAMIC SCANNER FAMILY
NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
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NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
SCANNERS HARDWAREscanning
capacity
PANNORAMIC Midi II 12 BF FL BF FL
PANNORAMIC 250 Flash III 300 BF FL BF
PANNORAMIC Desk II DW 1 BF BF
PANNORAMIC 1000 1000 BF BF
PANNORAMIC Confocal 11 BF FL
PANNORAMIC Scan II 150 BF FL
RESEARCH DIAGNOSTICS
PANNORAMIC SCANNER FAMILY – TYPE OF SCANNER ILLUMINATION
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NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
MIDI II (12) Scan II (150) P250 Flash III (300) Confocal (12) Desk II DW (1) P1000 (1000)
MIDI II (12) Desk II DW (1) P250 Flash III (300) P1000 (1000)
DIAGNOSTICS (DX) HARDWARE PORTFOLIO
BR
IGH
TFIE
LD
RESEARCH (RX) HARDWARE PORTFOLIO
BR
IGH
TFIE
LDFL
UO
RES
CEN
TFL
UO
RES
CEN
T
SCANNER FAMILY – TYPE OF SCANNER ILLUMINATION
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NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
PANNORAMIC SCANNER FAMILY – HW&SW
SCANNERS HW + SWscanning
capacity RESEARCH DIAGNOSTICS
PANNORAMIC Desk II DW 1 PANNORAMIC Scanner SW 3.0 PANNORAMIC Diagnostic Scanner SW 1.0
PANNORAMIC Midi II 12 PANNORAMIC Scanner SW 3.0 PANNORAMIC Diagnostic Scanner SW 1.1
PANNORAMIC 250 Flash III 300 PANNORAMIC Scanner SW 3.0 PANNORAMIC Diagnostic Scanner SW 1.0
PANNORAMIC 1000 1000 PANNORAMIC 1000 Scanner SW 3.0 PANNORAMIC Diagnostic Scanner SW 1.0
PANNORAMIC Confocal 11 PANNORAMIC Scanner SW 3.0
PANNORAMIC Scan II 150 PANNORAMIC Scanner SW 3.0
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Scanning Profile –
FLEXIBLE
Output resolution
Image SettingImage Quality
Compression typeUse compensation image
Focus Quality
Sample detectionAutothreshold
Manual ThresholdDrew scan area
Objective type
Focus settingLimite the rangeFocus Distance
Scan SettingsStop and Go
FlashColor Matrix
Filter Setting
Multilayerselection
Single LayerZ - layer scanning
Extended focusscanning
Preview typeBrightfieldDarkfieldPre scan
Focus modeInterpolate
AutoCoarse
File Format
NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
SCANNING PROFILE SETTINGS
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Scanning Profile –
STANDARDIZED
Output resolution
Image Setting
Image QualityCompression type
Sample detectionAutothreshold
Manual ThresholdDrew scan area
Objective type
Focus settingLimite the rangeFocus Distance
Scan Settings
Stop and GoFlash
Filter Setting
Multilayerselection
Z - layer scanningExtended focus
Preview typeBrightfieldDarkfieldPre scan
Focus mode
InterpolateAuto
Coarse
File Format
NEW PRODUCT PORTFOLIO CONCEPT IN RX AND DX MARKETS
SCANNING PROFILE SETTINGS
Fully Automated
FullyAutomated
FullyAutomated
FullyAutomated
Fixed
Fixed
Fixed
Fixed
Fixed
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NEW PRODUCT PORTFOLIO CONCEPTIN RX AND DX MARKET SEGMENTS
RX DX
*diversed scanning profile settings *settings are fixed or automated
*anyone can start scanning without password *starting scanning with user password only (security)
*self-calibration (once, at start) *continuous self-calibration (per 4 hours or per 200 slides)
*error reports stay within the internal system *central log service = error reports are sent from the internal system to technicians
*color profile is diversed *color profile is fixed (reproducible colors)
MAIN DIFFERENCES IN FEATURES
NEW PRODUCT PORTFOLIO CONCEPTIN RX AND DX MARKET SEGMENTS
RX DX
*diversed scanning profile settings *settings are fixed or automated
*anyone can start scanning without password *starting scanning with user password only (security)
*self-calibration (once, at start) *continuous self-calibration (per 4 hours or per 200 slides)
*error reports stay within the internal system *central log service = error reports are sent from the internal system to technicians
*color profile is diversed *color profile is fixed (reproducible colors)
MAIN DIFFERENCES IN FEATURES
We are not a scanner manufacturer, but integrated digital pathology workflow supplier!
NEW PRODUCT PORTFOLIO CONCEPTIN RX AND DX MARKETSSCANNERS HW & SW RESEARCH
PANNORAMIC Desk II DW Pannoramic Scanner Software 3.0
PANNORAMIC 250 Flash III Pannoramic Scanner Software 3.0
PANNORAMIC 1000 Pannoramic 1000 Scanner Software 3.0
PANNORAMIC Midi II Pannoramic Scanner Software 3.0
PANNORAMIC Confocal Pannoramic Scanner Software 3.0
PANNORAMIC Scan II Pannoramic Scanner Software 3.0
TMA HW & SW RESEARCH
TMA MASTER II
TMA GRAND MASTER
SERVER BASED APPLICATIONS RESEARCH
Track&Sign
Case Manager
Case Center (DX) / Slide Center (RX) √
Clinical Viewer (DX) / Slide Viewer (RX) √
Instant Viewer √
Teleconsultation / E-Exam / Pathonet.com √
QUANT CENTER RESEARCH
Nuclear Quant √ HER2, Er, Prg √
Membrane Quant √ HER2, Er, Prg √
FISH Quant √
Pattern Quant √
HistoQuant √
Cell Quant √
Densito Quant √
CISH Quant √
TMA Control Software 3.2
Pannoramic Diagnostic Scanner SW 1.0
Pannoramic Diagnostic Scanner SW 1.0
Pannoramic Diagnostic Scanner SW 1.0
√
Clinical
Study for
IVDR will
be run
Clinical
Study for
IVDR will
be run
have IVD
already
DIAGNOSTICS
√
√
DIAGNOSTICS
DIAGNOSTICS
DIAGNOSTICS
Pannoramic Diagnostic Scanner SW 1.1
√
√
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SERVER BASED APPLICATIONS
Track&Sign
CaseManager
CaseCenter (DX) / SlideCenter (RX)
CaseViewer (DX) / Slide Viewer (RX)
Instant Viewer
Teleconsultation / E-Exam / Pathonet.com
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NEW PRODUCT PORTFOLIO CONCEPT
COMPLEX SOLUTION IN CLINICAL ROUTINE (DX)PANNORAMIC PATHOLOGY DIAGNOSTIC SYSTEM
• SCANNERS (P1000, P300, DESK II) + NEW DX SCANNER SOFTWARES
• + Case Manager 2.1
• + Case Center 3.0
• + Case Viewer 2.5
• + Breast quantification panel (IVD: HER2, Er, Pr)
The products of PPDS for routine pathology can not be purchased individually, only as a package.
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PANNORAMIC MANAGEMENTSYSTEM
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NEW PRODUCT PORTFOLIO CONCEPTCOMPLEX SOLUTION IN DX – PANNORAMIC MANAGEMENT SYSTEM
26X
NEW PRODUCT PORTFOLIO CONCEPTImage analysis for DX applications
• Quick (quantification starts with one click)
• Decision is made by the doctor: area of annotation, diagnosis
• Quant modules help the diagnosis (IVD: HER2; Er; Pr) with calculations
The doctor has a presumed diagnosis.
NEW PRODUCT PORTFOLIO CONCEPT
The Pannoramic Pathology Diagnostic System:
• has to be integrated with a LIS, it is not a stand-alone solution
• we will run a Clinical Study for IVDR with PPDS as one system
• during manufacturing: testing according to strict rules
• delivery process: more rigorous and better documented
Converting the scanner of it to a RX scanner:
• for FL technology: light source+ camera + filters can be purchased additionally
• RX software can be also installed: two different types of software can run the same scanner
COMPLEX SOLUTION IN DX
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NEW PRODUCT PORTFOLIO CONCEPTRX PRODUCT PORTFOLIO
The products of our Research (RX)
portfolioCAN BE ORDEREDINDIVIDUALLY.
PANNORAMIC Desk II DW
PANNORAMIC Midi II
PANNORAMIC Confocal
PANNORAMIC Scan II
PANNORAMIC 250 Flash III
PANNORAMIC 1000 PANNORAMIC 1000 Scanner Software 3.0
TMA MASTER II
TMA GRAND MASTER
Slide Center √
Slide Viewer √
Instant Viewer √
Teleconsultation / E-Exam / Pathonet.com √
Pattern Quant √
HistoQuant √
Cell Quant √
Densito Quant √
Nuclear Quant √
Membrane Quant √
FISH Quant √
CISH Quant √
SCANNERS HW & SW
TISSUE MICROARRAYERS HW & SW
SERVER BASED APPLICATIONS
QUANT CENTER APPLICATIONS Image Analysis Platform
TMA Control Software 3.2
PANNORAMIC Scanner Software 3.0
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NEW PRODUCT PORTFOLIO CONCEPT
RX PRODUCT PORTFOLIO
TMA GRAND MASTER AND TMA MASTER II – HW&SW
• With the new TMA software 3.2 we will take an other step to complete our workflow
• As a result of the improved PCR system function we can send the samples to molecular analysis.
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NEW PRODUCT PORTFOLIO CONCEPT
Image analysis in RX
• Quant modules help the verification with calculations
• Lots of data - statistics
• The whole slide is processed for analysis
• Researcher can go down to cell level
The doctor has a concept to verify.
Pattern Quant
HistoQuant
Cell Quant
Densito Quant
Nuclear Quant
Membrane Quant
FISH Quant
CISH Quant
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NEW PRODUCT PORTFOLIO CONCEPT
Teleconsultation / E-exam / Publication portalfor Universities and medical students
TELECONSULTATION function in Case Center• E-learning, real time consultation and case show for students
E-AXAM modul (E-school) in Case Center• Surface for teachers – exam questionner• Surface for students – test (slides are opened with Case Viewer / Instant Viewer• Exam is closed: student can check the result
PUBLICATION Portal (Pathonet)• 1. Online web page• 2. Product for Universities (within Case Center)• Purpose: slide sharing, case description, consultation, own slide collection *
THE KEY FOCUS OF EDUCATON:• SALES PRODUCTS• DIGITALIZATION WILL BE NATURAL FOR THE NEW GENERATION OF
PATHOLOGISTS!
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• DX Pannoramic Management System – from 1st of July
• New P250/300 capacity – Q2
• New Flash Desk – Q3
• New RX Case Viewer 2.4. – Q2
• New RX scanner software solutions – May-June
• New DX software solutions - July
• New RX Slide Center version– summer
• New RX Slide Viewer version - summer
• New TMA software 3.2. – Q3
• Product&Service Catalogue and Ordering Guide (RX/DX)
• Price list
• Product Launch Kits
• Release notes and new product announcements
NEW PRODUCT PORTFOLIO CONCEPT - AVAILABILITY
Follow the launch procedure.
• Marketing support (RX and DX concept focus)
▪ Exhibitions and symposiums (at this moment we are virtually involved due to
Covid-19 situtation)
▪ Distributor Meeting topics
▪ Product brochures
▪ Webpage update
▪ Product videos and webinars
▪ Online media news (Tissuepathology.com)
▪ Newsletters / Social Media news
NEW PRODUCT PORTFOLIO CONCEPT - AVAILABILITY
Follow the launch procedure.
• Marketing support (RX and DX concept focus)
▪ Exhibitions and symposiums (at this moment we are virtually involved due to
Covid-19 situtation)
▪ Distributor Meeting topics
▪ Product brochures
▪ Webpage update
▪ Product videos and webinars
▪ Online media news (Tissuepathology.com)
▪ Newsletters / Social Media news
NEW PRODUCT PORTFOLIO CONCEPT - AVAILABILITY
Follow the launch procedure.
Future of Technical Trainings:
Division into RX and DX parts
THANK YOU
FOR YOUR ATTENTION!