Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

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Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!
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    12-Jan-2016
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Transcript of Regents Biology Mitosis & Cancer: When Making New Cells Goes Terribly Wrong!

Biology is the only subject in which multiplication is the same thing as division…When you have to add or replace cells
growth & development
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special proteins (ie. CYCLIN) monitor cell activities & send info to nucleus
nucleus instructs cell whether or not to divide / grow
Regents Biology
there are not enough nutrients to support cell growth
DNA is damaged
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It seems human cells are pre-programmed to reproduce up to 50 or 60 times maximum. Then they will eventually die. Stem cells provide a pool of dividing cells that the body uses to restock. Other things can cause the cell to self destruct before itgets as far asdoubling 60 times. If the genes of a cell are very badly damaged, or if it becomes detached from its proper place as explained above, it will commit suicide. This PROGRAMMED self destruction is called 'apoptosis'.
Regents Biology
When cells reproduce & they are not needed
these cells take over organs, but don’t do the right job
they just keep making copies
cancer
nearby blood vessels provide nutrients to the tumor
blood vessels carry cancer cells to new location
larger than normal nuclei, since they have more chromosomes than they should
Regents Biology
Healthy Cells
stop dividing when they receive messages from neighbouring cells
Cancer Cells
do not respond to messages from neighbouring cells…continue to divide
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If DNA gets damaged, cells stop listening to correct instructions
mutations
most do not cause serious problems &
can be removed by surgery
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start more tumors
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chemotherapy
radiation
side effects
Assignment: