Reduce Cycle Time - Agilent’s ELN v4.0 101409.ppt · 2016-08-30 · ICP-MS LC UV-vis GC/MS GC...

Agilent ELNO t b 14th 2009

Reduce Cycle Time: Faster Access to Analytical

October 14th, 2009

Reduce Cycle Time: Faster Access to Analytical Results with Agilent’s ELN

Copyright © 2009 Agilent Technologies Inc.

Agenda

• Introduction on Agilent Software and Informatics portfolio

Agilent ELN overview• Agilent ELN overview

• Analytical environment: from analysis request to final results– Configuration overview– Streamlining the communication between labs through analysis

requests – Using dynamic forms to simplify scientists work– Fully integrated workflow support with the addition of OpenLAB ECM

Ill t ti– Illustrations

• Benefits


Agilent ELN: part of the integrated Agilent solution

GC CELC Lab-on-a ChipGC/MS LC/MSICP-MS UV-vis

Multiple inputs—Data coming from instruments and other documents/information used to document research (input)

ELN PDF Images DrawingsLIMS ResearchMS OfficeLegacy Data

Agilent ELN Electronic Laboratory Notebook

Knowledge

OpenLAB ECMEnterprise Content Management

yExperimentsand Insights

Data Storage and Other

Applications (LIMS Specialized Software

CDS/ICM/GeneSpring/EZChromChemstation/MassHunter

Third PartyCh li E T t lCh

Organization

Scientific Data Generators

(LIMS, inventories,

etc.)

Support and Professional Services

From data to knowledge, Agilent Technologies helps laboratory managers and

Chromelion, Empower, TotalChrom…

Data


directors reduce the time, effort, and cost to go from raw data to final insight.

Agenda






• Benefits


What is Agilent’s ELN ?

• A Web-based ELN which enables you to…

• Document, manage and analyze across multiple disciplines with a single solution

• Search and collate disparate data sources i t i l i t ith hi h l l finto single experiment with high level of traceability

• Reduce cycle times with integrated workflow processing and improve lab efficiencyprocessing and improve lab efficiency

• Integrate with existing information systems as well as IP protection tools

• Resulting in…

• Improved efficiency and data quality


• More secure Intellectual Property protection

Document, manage and analyze across multiple disciplines with a single solutiondisciplines with a single solution

ChemistrySynthetic chemists– Synthetic chemists

– Analytical chemists– BiochemistsBiology– Cell biology

Toxicology– Toxicology– Molecular biologyBioprocessingBioengineering…


For the synthetic chemists…

• Plan and design reactions • Integrate with existing registration systems g g g y

and sourcing databases• Create favorites menu for commonly used

reagents and solventsg• Reduce redundant experiments; search

across reactions and molecules• Create standard sentences and templates• Create standard sentences and templates• Create batches, split samples and submit

for analysis directly from the experiment


For analytical chemists…

• Reduce cycle time with Request Workflow

• Import directly from instruments with Smart Importwith Smart Import

• Capture images, chromatograms, spectra; fully searchable p yannotations

• Save time creating experiments ith D i Fwith Dynamic Forms


For the biologist and other disciplines…

• Rich text environment for free-form data entry– Control font, type, style– Create tables, embed Excel, Word, PowerPoint

• Insert images, searchable annotations• Quickly create experiments using• Quickly create experiments using

– Standard sentences or paragraphs– One or more Dynamic Forms– Clone previous experiments

• Link to external sources (e.g. websites, documents), import data and results


Agenda






• Benefits


Case studyConfiguration overview

• The Agilent ELN system is based on the following components:p

– Chemistry environment that covers: Unitary synthesis as well as Purification experiments

– Analytical Request Module– Analytical environment that covers Separation Techniques (LC, GC),

Structural Analysis (NMR, MS, IR, UV, ICP), Powder Analysis Techniques and General Analysis thanks to dynamic forms

– OpenLAB ECM


Case study Streamlining communication between labs through analysis requests

Analysis Request Project manager Scientist Instrument

ChemicalSample

Analysis Request (with context)

+• Review, accept or update the Analysis Request• Register Sample• Store the sample + ff t th AR t

• Execute the next requested analysis

( )affect the AR to one lab • Generate Raw Data

• Print the experimental run’s report

• Review AR• Record result• Print the experiment report (all available results) and attach it to the AR

• If AR completed: 1. Enter

conclusion2. Generate the

global report, Chemical Analysis Request+

• Transmit AR + sample to the next lab

signs it and send it to the submitter

C e caSample

Analysis Request completed with

results and conclusions


Case study Using dynamic forms to simplify scientists work

• Creating dynamic forms allows to:

– Fit to an organization practicesg p– Guide scientists into the workflow– Automate basic tasks (calculations) and create links with other existing tools

• Dynamic forms capabilities include:• Dynamic forms capabilities include:

– Structured elements (both fields and forms) to be incorporated into rich texts (protocol/result templates) which become automatically searchable

– Action buttons can also be incorporated which include scripting capabilities (to manipulate forms elements but also other elements of the current experiment)

– Forms organization is fully flexible in a user-defined hierarchical tree

• Access to dynamic forms is configured

– Rules to use or edit forms are defined for each form or propagated from the top level


Case study Using dynamic forms to simplify scientists work


Case study Fully integrated workflow support with the addition of OpenLAB ECM

• OpenLAB Enterprise Content Management (ECM) consolidates and manages all scientific datag

– Store instrument data as well as human readable data– Extract searchable meta-data

• Integration with OpenLAB ECM bridges the gap between raw data capture and experiment conclusions



Agilent ELN levelConduct experimentsR f t l ti l d t

Agilent ELN ServerRefer to analytical data (global)

Send Batch ID, Keywords...

Find and linkFind and link associated data...

ECM levelStore analytical data from instruments locallyConsult data locally/globally

ECM Server ECM Server ECM Server


Site 1 Site 2 Site 3


1. Data generationfrom instruments

3. Meta data keys are extracted

ECM Server2. Report is captured into ECM

a e e t acted



Values extracted from raw data are inserted

into an Excel sheet and used for calculationsused for calculations


Case study Illustrations - Workflow overview

Review

Analysis Request

Experiment Planning Perform SynthesisReview request

Analytical Data

Analytical Testing

Analysis are

Review results

ycompleted Observations and

ConclusionsRaw data capture


Perform SynthesisReview request Analytical Testing

Observations andConclusions

Review results Conclude Synthesis

Case study Illustrations – Starting from the chemical reaction & protocol


Case study Illustrations – The structure elucidation starts …

Batch selection Sample creation


Case study Illustrations – … by creating several samples …

Sends a request to analytical labs


Case study Illustrations – New analysis request

Access to thechemistry data

Destination lab is selectedchemistry data

Request can be described

Rich textRich text

Sample list

Analysis can be specified


Case study Illustrations – … request monitoring is directly available …

Link to the request Status of the request


q q

Case study Illustrations – … request is handled by the lab manager …


Case study Illustrations – … request is filled and accepted …


Case study Illustrations – … analysts start the requested work …


Case study Illustrations – … HPLC first …


Case study Illustrations – … Sample preparation …


Case study Illustrations – … Methodology …


Case study Illustrations – … Results …


Case study Illustrations – … Report is automatically generated…


Case study Illustrations – … NMR is also processed …


Case study Illustrations – … NMR parameters …


Case study Illustrations – … NMR results…


Case study Illustrations – … Chemist can monitor the activity …

Status of the analysisLink to the analysis


yy

Case study Illustrations – … and concludes on batch content …


Agenda






• Benefits


Benefits

• Activity Profiles combined with dynamic forms provide each scientist with a dedicated environment to support their workpp

• The Analytical Request Module speeds up the communication between labs and gives access to the entire set of data

• Integration with OpenLAB ECM bridges the gap between raw d t t d i t l idata capture and experiment conclusions

• The Agilent ELN Web architecture facilitates the deployment within all these different groupswithin all these different groups


Questions / Answers

Thank you for your attention


Reduce Cycle Time - Agilent’s ELN v4.0 101409.ppt · 2016-08-30 · ICP-MS LC UV-vis GC/MS GC...

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