Recent advances in acid peptic diseasedownloads.hindawi.com/journals/cjgh/1993/565930.pdf ·...

$: Recent advances in acid peptic diseasedownloads.hindawi.com/journals/cjgh/1993/565930.pdf · INTRODUCTION Recent advances in acid peptic disease tvitt ·111.111\1· Sn-M \Im, tvt[),$
INTRODUCTION

Recent advances in acid peptic disease

tvitt ·111.111\1· Sn-M \Im, tvt[), FRl:P<. '

IN 1111 P\',l l)l't',\ll1,-.;1t;\J1Jlt \\Jf \11\ \Nt·f'-,Jl'\VI Hl-1'1

1rn1dl' in undn,t.111d1ng, im l',t rg;ll in.!..! .md man.igmg ;1cid J1l'J111C dr,L',hc, ,lllh ;1, g;1,11-.1c,u1,h:igl'.1I rl'flux drsc,1,c ( ( ,r.Rl)), pcpt i c u ker d r,c, l.'l' ,m, I ,ga,t ri 11,. f\ nu 111 her , if 1111purt.ini clinic.ii dcci,1nn, rwnl 1" h : rc-c-.:.1111incd in thl· ligh1 <>f Ill'\\' i nfPrm.n ion on t lw l'l''Lk-1111, ilog\, ,,:11h11gL·nc,i, ,md rrcmment uf tlw,1.· di,ord1.·r,. 111 nrlll'r 1,1 keep rt., memher, u1Ho-d:1tc 011 the,,: rrnpllrl :1111 i"ue,, the ( :anmli;m A"ncr.1-tio11 pf Ci,htruentc·rolog) ,1rg;1111:ed thl· 'lil'ntilic progr:1111 of ;I ,y111po,1u111 enl itlcd 'Rl'l:l'nl Ad1·:111e1.·, in Aud rc,,t IC D1,en,l'' whilh 11·;1, hL'ld 111 T,1rornu, Ont.irr,1 in N11\l'lllhl-r 1992.

TIK ,~mpo,ium ftr,t .rddrl',,l·d thl' nilc ,i( I ldico/i<1ctcr /1)'lori ,1, a ga,1ru1ntl·,1111:rl ((~ I) p;1th,1,i_:l·n. Thl· e,tim,1ted rate nf 11 /rylori ink1.11,1n i, ·li'JW1>:--irn,1tcl) [''., per )enr in the general popul.1ti,n1. l'll'll'Ct i,111 u(thc org;111hn1 rs rn111· pn"ihle ll'ith ,impk di.rgn, 1,111. 111L'l hud,. Thl' rule , i( 11 /rvlon in dbca,l·, ,uch :1., g:r,trit i,, du11den,1I ulcer, .rnd g:1't rr1. lllL't.lpla,ia, a, ll'cll ,1, 11, q,1dcm111IP.!..!)' ,md d1ag111,,i,, ,lrl' di,Lu,,ed

in the lcml nniclc. On1.e 111,!.!l',ll'll. 11 i, k111ll111 1h:11 I I /1~/nri will prd·1.·r1.·11ti,1II) cul,111i:e tlw g<1striL ;111tru111; thl' rcL11iP11-,hip hetw1.-cn the pre,c·nc1.· ol 11 /r:,·/riri in the ,tP111:1ch and the pathogc11es1, nf ga.,11'11 i,, n, in11kn dy,pq'-1:1, l'l'l't tc ukLT d1,e,1sc and g:1,tric Cilrl i11\lma i, rl',·11.·11·cd. Fin:1lly, m,m,1g1.·111c111

/J11n11m of l'cduunc ( ;(l,rr, i.·tHl'rnl, ,g,, I lc/><1rn11c•111 , ,f l'edr11mc,. Dallw11.11r ( 'n11•cr11!", J l,d1(cl\ , Norn \c11u,1

Con\•.1/>ondencl!· fJr l\l1d1elme :-i1e ,'d11nc, /\'\ '{,: I lrnpw,I. 'iR."iLl l '1111•ersi1;1 A1•cn11,•. I /11/r/11\ , N111·,1 \ ro1w /H_/ {( ;9 /'dr/1i11J111! (9L12J .J2K-8746

1if 11 /ry/ori .t!a,tritis and duodcn.il ukn, ,md rl'LL'nt trial, 111 douhk .ind tnpk thcr:lp) r1)r h.11.11.•ri:d cradiullilln me div Cli',Sl'd.

Till' t::in.idi.m A,,()Llilli"n u( (,,1,trncnternlngy h:1, r1.·cc·11tly puhl1,hed :1 Cll11'L'nsu, ,tatemcn1 ,in tlw llT:lllllL'nt Ill g,1'tn11.·,llphat:l',d rcflu-.: dbe.i,L' (I) . Thl' rllk 111 I I~ rL'u:plllr :111r:1gllni,1,, prokrnctic, :md t'rPtnn pum11 inhrhrtPr, 111 the t rc:irmcnt ll( c ,l'RI l 11·:h ,um111:1r1:ed during t hl' ') mpu, iurn !dent 1i'il at111n llf high rr,I.. .t!rn11p, .111d indic,ll ion, fnr long term ther:ipy of ( ,I-RI) c, 111eludcd th b 'l'''ion.

Tlw rel ,Hi11n,h rp hctwe1.·11111n1,tL'r\l1d,il :i1111-i11flam111,1tor) drug, (N~.'\JI 1,) and llJ'l'L'r (~I mucosa I d;1m:1gL' r1.·m,1i11s ,11111cll'h :1 t Clllllrm·1.·r,ial. Rccl'llt c l11\11.·:d tn:d re,u lts ll'l'l'l' reviewed and indiu 111ons fur prllphylaxrs 111 ,ekul'd ,uh,grn11ps nf high ri,I.. pm 1ent, Wl'rc discussed. T he ') mp<>sium 1.'11lk·d with a 1T1·1c11 nf m11dc, ,if 1hl'l':IJ))' ,,f .tLid-11wdi:11l'd peptic ulcer drsc:1,l', 111chrcli11t.: ,h,,n tl'rm hl·alint.: ;md l,111g rcrm maintc-11.incL'-

A, tlw l'ilj'lT' 111 1hr, ,,n,L1.'cd1nc, dc111<l11strntL·, s1.•ver:1I qtrl·,111111, tTm;1111 1111;111,11'L'l'l'll. ()11}!P111g Llinrc,il resemch is 11l'l'Lkd 1,11dcn11f) ,,:1n1cular ,1,h,d, ,1l p:111L·111 gnnq1s m r1'k fur de1·clup111.!..! ,llld l'L'l''111 d isea.,c ,md 111 idL·ntily till' hl',t t her:1peu1 ic rl't.:i1111.·11, lnr rhl' cradic:1t ion pf I I /1ylon, long tl'rm 111an.1).Ll'mc111 oft ;)'IZJ ) :ind prc\'C lll lPll of Ci! rnucn,:11 drnn,l.l(L'

I rnm N..., \II),.

REFERENCE I . ill·lk IT. C.mnon J, Ll'mr rl' ::->. Th1,111,nn .I\HIZ. ( 'an.1d1.m

( :nn,L·n,u, <. \,nll'rL·nn· Pn r he Trc,11 mc·111 , ,f ( ;,hi n>l'" >ph.1.t:l',il Rcflu, I )rsl',hl', ( :,rn _I ( ~.1,1 n ll'llll'rol 1992:"i:277 S<J.

$: Recent advances in acid peptic diseasedownloads.hindawi.com/journals/cjgh/1993/565930.pdf · INTRODUCTION Recent advances in acid peptic disease tvitt ·111.111\1· Sn-M \Im, tvt[),$
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