Reactions of Enols and Enolates

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Reactions of Enols and Enolates

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Reactions of Enols and Enolates. The Aldol Condensation Reaction. Ketone Enolate + Aldehyde. Intramolecular Aldol. Ester Enolate + Aldehyde. Ester Enolate + Ester = Claisen Condensation. Intramolecular Claisen Condensation = Dieckmann Condensation. - PowerPoint PPT Presentation

Transcript of Reactions of Enols and Enolates

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Reactions of Enols and Enolates

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The Aldol Condensation Reaction

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Ketone Enolate + Aldehyde

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Intramolecular Aldol

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Ester Enolate + Aldehyde

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Ester Enolate + Ester = Claisen Condensation

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Intramolecular Claisen Condensation = Dieckmann Condensation

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1,4-Conjugate Addition: The Michael Reaction

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Decarboxylation Reactions

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Chapter 18: Enols and Enolates

Chapter 18: Enols and Enolates

Chapter 21 Enols and Enolates - Long Island Universitymyweb.liu.edu/~swatson/downloads-4/files/Chapter_21.pdf · Chapter 21 Enols and Enolates There are two major types of reactions

Chapter 21 Enols and Enolates - Long Island Universitymyweb.liu.edu/~swatson/downloads-4/files/Chapter_21.pdf · Chapter 21 Enols and Enolates There are two major types of reactions

Structure and Reactivity of Lithium Enolates. From … · seemingly simple standard reactions of organic synthesis. ... enolates and chiral Li amides can ... From the deprotonated

Structure and Reactivity of Lithium Enolates. From … · seemingly simple standard reactions of organic synthesis. ... enolates and chiral Li amides can ... From the deprotonated

Evans Enolates: Solution Structures of Lithiated ...collum.chem.cornell.edu/publications/130.pdf · Evans Enolates: Solution Structures of Lithiated Oxazolidinone-Derived Enolates

Evans Enolates: Solution Structures of Lithiated ...collum.chem.cornell.edu/publications/130.pdf · Evans Enolates: Solution Structures of Lithiated Oxazolidinone-Derived Enolates

Catalytic, asymmetric reactions of ketenes and ketene …lectka.chemistry.jhu.edu/assets/Publications/sdarticle.pdf · Catalytic, asymmetric reactions of ketenes and ketene enolates

Catalytic, asymmetric reactions of ketenes and ketene …lectka.chemistry.jhu.edu/assets/Publications/sdarticle.pdf · Catalytic, asymmetric reactions of ketenes and ketene enolates

Enolates, Enols, and Enamines Part 1 - Chemistry2011.org · Enolate Enol alkene + alcohol Enamine alkene + amine O ... Enolates, Enols, and Enamines Part 1 Lecture Supplement -- Page

Enolates, Enols, and Enamines Part 1 - Chemistry2011.org · Enolate Enol alkene + alcohol Enamine alkene + amine O ... Enolates, Enols, and Enamines Part 1 Lecture Supplement -- Page

Alpha Carbon Chemistry - Enols and Enolates

Alpha Carbon Chemistry - Enols and Enolates

Chapter 18: Enols and Enolates Overview Enols : Enolates :

Chapter 18: Enols and Enolates Overview Enols : Enolates :

Reactions of enolates with carbonyl compounds

Reactions of enolates with carbonyl compounds

Reactions of Enolate Anions: Enolates + Electrophiles II

Reactions of Enolate Anions: Enolates + Electrophiles II

Reactions of Enols and Enolates. Ketones and aldehydes are in equilibrium with a small amount of the corresponding enol. This can be problematic, if one.

Reactions of Enols and Enolates. Ketones and aldehydes are in equilibrium with a small amount of the corresponding enol. This can be problematic, if one.

Chapter 20: Enols and Enolates

Chapter 20: Enols and Enolates

20 Characteristics of Enols And Enolates answers Characteristics of... · Keto-Enol Tautomers Of Other Compound Types ... MeO-+ H OH OMe -HO-O-OMe OH H OMe O ... 20 Characteristics

20 Characteristics of Enols And Enolates answers Characteristics of... · Keto-Enol Tautomers Of Other Compound Types ... MeO-+ H OH OMe -HO-O-OMe OH H OMe O ... 20 Characteristics

Enols and Enolates

Enols and Enolates

Mechanism Switch in Mannich-type Reactions. ELF and NCI ... · unsusbtituted enolates. Introduction Mannich-type reactions are probably the most popular approach for the synthesis

Mechanism Switch in Mannich-type Reactions. ELF and NCI ... · unsusbtituted enolates. Introduction Mannich-type reactions are probably the most popular approach for the synthesis

17. Enols, Enamines, Enolates · Enolate Formation with LDA Recall: Li enolates = 99% dimer, but monomer alkylates faster Dave Collum JACS 2000, 2452. Collum, D. B. Acc. Chem. Res.

17. Enols, Enamines, Enolates · Enolate Formation with LDA Recall: Li enolates = 99% dimer, but monomer alkylates faster Dave Collum JACS 2000, 2452. Collum, D. B. Acc. Chem. Res.

Stereoselective reactions of enolates

Stereoselective reactions of enolates

ENOLS ET ENOLATES O H Énol O Base H-Base H C O H C Énolate O H C ... - Université Laval · 2017. 1. 8. · © Thierry Ollevier Chimie organique II CHM-2000 ENOLS ET ENOLATES O

ENOLS ET ENOLATES O H Énol O Base H-Base H C O H C Énolate O H C ... - Université Laval · 2017. 1. 8. · © Thierry Ollevier Chimie organique II CHM-2000 ENOLS ET ENOLATES O

Enolates, Enols, and Enamines Part 2

Enolates, Enols, and Enamines Part 2

Stereoselective reactions of enolates - Massey Universitygjrowlan/stereo2/lecture7.pdf · 123.702 Organic Chemistry C-α si face C-α re face Stereoselective reactions of enolates

Stereoselective reactions of enolates - Massey Universitygjrowlan/stereo2/lecture7.pdf · 123.702 Organic Chemistry C-α si face C-α re face Stereoselective reactions of enolates