Rapid Room Temperature Buchwald—Hartwig and Suzuki—Miyaura Couplings of Heteroaromatic Compounds...

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2006 Pyridine derivatives R 0380 Rapid Room Temperature Buchwald—Hartwig and Suzuki—Miyaura Couplings of Heteroaromatic Compounds Employing Low Catalyst Loadings. — The title reactions of a variety of aryl halides with amines and boronic acids are carried out under the optimized conditions shown. It is possible to operate with a catalyst loading of 0.001 mol%, but higher temperatures and elevated reaction times (up to 2 d) are required. — (NAVARRO, O.; MARION, N.; MEI, J.; NOLAN*, S. P.; Chem. Eur. J. 12 (2006) 19, 5142-5148; Dep. Chem., Univ. New Orleans, New Orleans, LA 70148, USA; Eng.) — Y. Steudel 44- 148

Transcript of Rapid Room Temperature Buchwald—Hartwig and Suzuki—Miyaura Couplings of Heteroaromatic Compounds...

Page 1: Rapid Room Temperature Buchwald—Hartwig and Suzuki—Miyaura Couplings of Heteroaromatic Compounds Employing Low Catalyst Loadings.

2006

Pyridine derivativesR 0380 Rapid Room Temperature Buchwald—Hartwig and Suzuki—Miyaura Couplings

of Heteroaromatic Compounds Employing Low Catalyst Loadings. — The title reactions of a variety of aryl halides with amines and boronic acids are carried out under the optimized conditions shown. It is possible to operate with a catalyst loading of 0.001 mol%, but higher temperatures and elevated reaction times (up to 2 d) are required. — (NAVARRO, O.; MARION, N.; MEI, J.; NOLAN*, S. P.; Chem. Eur. J. 12 (2006) 19, 5142-5148; Dep. Chem., Univ. New Orleans, New Orleans, LA 70148, USA; Eng.) — Y. Steudel

44- 148