Presented by: Dr Rakesh Jain SR, Dept of Cardiology Govt. Medical College, Calicut.
Rakesh K. Jain Scientific American 2014...Rakesh K. Jain Scientific American Image of snake removed...
Transcript of Rakesh K. Jain Scientific American 2014...Rakesh K. Jain Scientific American Image of snake removed...
Rakesh K. Jain Scientific American
Image of snake removed due to copyright restrictions. Source: Jain, Rakesh K. "An indirect way to tame cancer." Scientific American 310, no. 2 (2014): 46-53.
2014
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Figures from Box 1 removed due to copyright restrictions. Source: Jain, Rakesh K. "An indirect way to tame cancer." Scientific American 310, no. 2 (2014): 46-53.
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Figures from Box 2 removed due to copyright restrictions. Source: Jain, Rakesh K. "An indirect way to tame cancer." Scientific American 310, no. 2 (2014): 46-53.
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Cortical myosin
assembly
Cortical actin
assembly
Courtesy of Macmillan Publishers Limited. Used with permission. Source: Charras, Guillaume T. et al. "Non-equilibration of hydrostatic pressure in blebbing cells." Nature 435, no. 7040 (2005): 365-369.
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Cortical myosin
assembly
Microplast (cell fragment) volume remains constant during blebbing
Courtesy of Macmillan Publishers Limited. Used with permission. Source: Charras, Guillaume T. et al. "Non-equilibration of hydrostatic pressure in blebbing cells." Nature 435, no. 7040 (2005): 365-369.
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Increasing extracellular osmolarity makes blebs smaller
Courtesy of Macmillan Publishers Limited. Used with permission. Source: Charras, Guillaume T. et al. "Non-equilibration of hydrostatic pressure in blebbing cells." Nature 435, no. 7040 (2005): 365-369.
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Increasing membrane rigidity inhibits blebbing
Courtesy of Macmillan Publishers Limited. Used with permission. Source: Charras, Guillaume T. et al. "Non-equilibration of hydrostatic pressure in blebbing cells." Nature 435, no. 7040 (2005): 365-369.
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cortical acto-myosin contraction bleb forms (rupture event)
pore-size or fluid flows mesh-size through pores due
to hydrostatic pressure
Courtesy of Macmillan Publishers Limited. Used with permission. Source: Charras, Guillaume T. et al. "Non-equilibration of hydrostatic pressure in blebbing cells." Nature 435, no. 7040 (2005): 365-369.
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σ11
Figures 7.14 and 7.15 removed due to copyright restrictions. Source: Grodzinsky, Alan. Field, Forces and Flows in Biological Systems. Garland Science, 2011.
Fields, Forces, & Flows, Figures 7.14 & 7.15
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20.430J / 2.795J / 6.561J / 10.539J Fields, Forces, and Flows in Biological SystemsFall 2015
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