Radiobiology1

27
Prof.Dr.Tarek Elnimr L 1 Presented to the Biology Departments in Faculty of

Transcript of Radiobiology1

Page 1: Radiobiology1

Prof.Dr.Tarek Elnimr

L 1Presented to the

Biology Departments in Faculty of

Scienceson February 15 ,

2009

Page 2: Radiobiology1

THE ATOMThe nucleus structure

protons and neutrons = nucleons Z protons with a positive electric charge

(1.6 10-19 C) neutrons with no charge (neutral) number of nucleons = mass number A

The extranucleus structure Z electrons (light particles with electric

charge) equal to proton charge but negative

2

Particle Symbol Mass Energy Charge (kg) (MeV)----------------------------------------------------------Proton p 1.672*10-27 938.2 +Neutron n 1.675*10 -27 939.2 0Electron e 0.911*10 -30 0.511 -

Page 3: Radiobiology1

3

Page 4: Radiobiology1

AXNZ

SYMBOL OF ELEMENT

MASS NUMBER (the number of protons and neutrons)

ATOMIC NUMBER (the number of protons)

53I78

131Example:

131I or I-131

The number of neutrons

Page 5: Radiobiology1

Definitions

04/12/23 VII.5

Isotope: Nuclides of same atomic number Z but different N (and A) same element

Nuclide: Species of atom characterized by the constitution of its nucleus (in particular N, Z)

Radionuclide: Nuclide of measurable half time

Radioactive decay : the process by which an unstable nucleus is transformed into a more stable daughter nucleus by emitting nuclear particles.

Page 6: Radiobiology1
Page 7: Radiobiology1

7

Isotopes I Atoms having the same atomic number are called isotopes

A=131 A= 127 Z= 53 Same Z= 53N= 78 N= 74

Page 8: Radiobiology1

Examples:i. lH11H21H3Hydrogen(Protium) Deuterium

Tritium(p= 1, e = 1, n = 0) (p=1, e = 1, n =

1) (p =l, e= l, n=2)

ii. 6C12, 6C13 and 6C14

Page 9: Radiobiology1
Page 10: Radiobiology1
Page 11: Radiobiology1

11

Isotones Atoms having the same number of neutrons are called isotones

X YA=131 A= 127 N= 53 Same N= 53Z= 78 Z= 74

Page 12: Radiobiology1

Examples : i4Si30,15P31 and i6Si32; 19K39 and 2oCa40 ; 1H3 and

2He4; and 6C13 and 7N14

Page 13: Radiobiology1
Page 14: Radiobiology1

14

Isobars Atoms having the same mass number are called isobars

I XeA=131 A= 131 Z= 53 Same Z= 54N= 78 N= 77

Page 15: Radiobiology1

Examples:i. 18Ar40,19K40 and 20Ca40;ii. 52Te130,54Xe130and 56Ba130.

Since isobars are the atoms of different elements, they will have

different physical and chemical properties

Page 16: Radiobiology1

Nuclear Isomers

Nuclear isomers (isomeric nuclei) are the atoms with the same

atomic number and same mass number but with different

radioactive properties. They have same number of electrons protons and neutrons.

Page 17: Radiobiology1

17

IsomersSimilar atoms having different internal energy are called isomers

Tc TcA=99m A= 99 Z= 43 Same Z= 43N= 56 N= 56

i

Page 18: Radiobiology1
Page 19: Radiobiology1

RADIOACTIVE OR METASTABLE

STABLE

Page 20: Radiobiology1
Page 21: Radiobiology1

Examples,i. 92U235 and 9oTh231ii. 19K39 and 9F19iii. 29CU65 and 24Cr55

Page 22: Radiobiology1
Page 23: Radiobiology1

Examples

i. N3-, O2-, F-, Ne, Na+, Mg2+, Al3+, CH4, NH3, H2O and HF have 10 electrons each.

ii. P3-, S2- , Cl , Ar, K+ and Ca2+ have 18 electrons each.

Page 24: Radiobiology1
Page 25: Radiobiology1

Example Naturally occurring boron consists of two isotopes whose atomic weights are 10-01 and 11-01. The atomic weight of natural boron is 10-81. Calculate the percentage of each isotope in natural boron.

Solution. Let the % of isotope with at. wt. 10-01 =x

.-. % of isotope with at. wt. 11.01 = (100 - x)Now since, At. wt. = 100x ´10.01+ (100 - x) ´11.0110.81 = 100x ´10.01+ (100 - x) ´11.01x = 20Hence % of isotope with at. wt. 10.01 = 20% of isotope with at. wt. 11.01 = 100 -20 = 80

Page 26: Radiobiology1

Part 2: Radiation Physics 26

Ques-tions?

Page 27: Radiobiology1