QIMP14+QIMP14 Dostors DirectoryQIMP14+Pharmaceutical Directory+QIMP14 Appnndix

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Section-1 DRUGS ACTING ON THE ALIMENTARY SYSTEM 21,22,23 The drugs and preparations acting on the alimentary system are classified into the following broad groups: 1. Antacids & other anti-dyspeptic drugs 2. Antispasmodics (anticholinergics). 3. Anticholinergic & anti-psychotic combination products 4. Motility stimulants / Dopamine antagonists 5. Ulcer-healing drugs. 6. Antidiarrhoeal drugs. 7. Drugs in chronic inflammatory bowel diseases. 8. Laxatives, purgatives & lubricants 9. Local preparations for anal and rectal disorders. 10. Drugs affecting intestinal secretions. 1. ANTACIDS & OTHER ANTI-DYSPEPTIC DRUGS 1.1 Antacids 1.2 Antacids with laxative action 1.3 Anti-dyspeptic & Carminatives ANTACIDS 21,22,23,33 Definition: Antacids are the most useful drugs for relief of hyperacidity & associated pain. Antacid preparations are weakly basic and consist of metal salts, most commonly aluminium hydroxide, magnesium hydroxide, calcium carbonate, or sodium bicarbonate. Mode of action: When antacids are ingested, these salts dissociate to neutralize gastric acid and form neutral salts within the stomach. Thus, the goal of antacid use is to increase the pH of gastric contents to a range of 3.5 to 4.5, at which pepsin activity is greatly diminished. Pain usually occurs when pH is below 3.5. There is good evidence from the clinical trials that antacids do not accelerate the rate of healing in gastric ulcer, but in duodenal ulcer, where very high doses of antacids such as 200-300ml of aluminium hydroxide daily in divided doses at frequent intervals well promote ulcer healing, but such treatment is inconvenient to the patient. Classification: Antacids are classified as: i. Systemic antacids: Which are usually absorbed from the gut so, these are preferable as blood alkaliser to combat acidosis rather than antacids, such as, sodim bicarbonate, sodium citrate, sodium acetate, potassium citrate. ii. Non-systemic antacids: These are not significantly absorbed from the gut and mainly used as antacids such as, aluminum hydroxide, magnesium hydroxide, magnesium trisilicate. Ind: Hyperacidity, gastric & duodenal ulcer, gastritis, heartburn, dyspepsia, gastro-oesophageal reflux disease, flatulence. C/I: Hypophosphataemia; if simethicone is added, contraindicated in renal failure, severely debilitated patients, 1st trimester of pregnancy. S/E: Diarrhoea, constipation, nausea, vomiting. Caution: Renal dysfunction, low phosphate diet, prolonged use. Dosage: See under individual preparations. ACEDONE-Z Tab. Zenith Dried aluminium hydroxide gel & magnesium hydroxide BP: tablet. Dose: 1-2 tabs. chewed half to 1 hour after or inbetween meals and at bed time or as required. Child: Not recommended. 250's pack:132.50 MRP ACEDONE-Z Susp. Zenith Aluminium hydroxide gel BP & magnesium hydroxide BP: suspension Dose: 2-4 tsf half to 1 hour after meals or when required and at bedtime. 200m1 bot: 32.50 MRP ACIDAX Susp. Apollo Aluminium oxide gel 180mg & magnesium hydroxide 200mg/5ml: suspension Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after or inbetween meals and at bedtime. 200ml hot: 31.40 MRP ACIDROX Susp. Syntho Aluminium hydroxide gel BP & magnesium hydroxide BP: suspension Dose: 2-4 tsf half to 1 hour after meals or when required and at bedtime. 200m1 bot: 32.00 MRP ACIDROX-M Tab. Syntho Dried aluminium magnesium polyhydroxy complex USP: magaldrate tablet Dose: 1-2 tablets 3 or 4 times daily half to 1 hour after or between meals & at bedtime. 150's pack: 150.00 MRP ACIDROX-M Susp. Syntho Hydroxy magnesium aluminate or magaldrate USP: magaldrate suspension. Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after or between meals and at bedtime. 200ml bot: 50.00 MRP ACINIL Tab. Somatec Dried aluminium hydroxide gel 250mg & magnesium trisilicate 500mg/tablet. Dose: 1-2 tabs chewed half to 1 hour after meals or as required and at bedtime. 200's pack: 100.00 MRP ACINIL Susp. Somatec Aluminium hydroxide & magnesium trisilicate BP: suspension Dose: 2-4 tsf half to 1 hour after meals or when required and at bedtime. 200m1 bot: 32.00 MRP ALGEX Tab. Doctors Dried aluminium hydroxide gel & magnesium hydroxide as tablet. Ind: Dyspepsia, hyperacidity, peptic ulcer, gastritis. Cautions: Renal impairment. Dose: 1-2 tabs. chewed half to 1 hour after or inbetween meals and at bed time or as required.

Transcript of QIMP14+QIMP14 Dostors DirectoryQIMP14+Pharmaceutical Directory+QIMP14 Appnndix

Section-1Mode of action: When antacids are ingested,these salts dissociate to neutralize gastric acid and form neutral salts within the stomach. Thus, the goal of antacid use is to increase the pH of gastric contents to a range of 3.5 to 4.5, at which pepsin activity is greatly diminished. Pain usually occurs when pH is below 3.5. There is good evidence from the clinical trials that antacids do not accelerate the rate of healing in gastric ulcer, but in duodenal ulcer, where very high doses of antacids such as 200-300ml of aluminium hydroxide daily in divided doses at frequent intervals well promote ulcer healing, but such treatment is inconvenient to the patient. Classification: Antacids are classified as: i. Systemic antacids: Which are usually absorbed from the gut so, these are preferable as blood alkaliser to combat acidosis rather than antacids, such as, sodim bicarbonate, sodium citrate, sodium acetate, potassium citrate. ii. Non-systemic antacids: These are not significantly absorbed from the gut and mainly used as antacids such as, aluminum hydroxide, magnesium hydroxide, magnesium trisilicate. Ind: Hyperacidity, gastric & duodenal ulcer, gastritis, heartburn, dyspepsia, gastro-oesophageal reflux disease, flatulence. C/I: Hypophosphataemia; if simethicone is added, contraindicated in renal failure, severely debilitated patients, 1st trimester of pregnancy. S/E: Diarrhoea, constipation, nausea, vomiting. Caution: Renal dysfunction, low phosphate diet, prolonged use.

required and at bedtime.200m1 bot: 32.50 MRP Aluminium oxide gel 180mg & magnesium hydroxide 200mg/5ml: suspension

ACIDAX Susp. Apollo

DRUGS ACTING ON THE ALIMENTARY SYSTEM21,22,23The drugs and preparations acting on the alimentary system are classified into the following broad groups: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. Antacids & other anti-dyspeptic drugs Antispasmodics (anticholinergics). Anticholinergic & anti-psychotic combination products Motility stimulants / Dopamine antagonists Ulcer-heali ng drugs. Anti diarrho eal drugs. Drugs in chronic inflammatory bowel diseases. Laxatives, purgatives & lubricants Local preparations for anal and rectal disorders. Drugs affecting intestinal secretions.

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after or inbetween meals and at bedtime.200ml hot: 31.40 MRP

ACIDROX Susp. SynthoAluminium hydroxide gel BP & magnesium hydroxide BP: suspension

Dose: 2-4 tsf half to 1 hour after meals or when required and at bedtime.200m1 bot: 32.00 MRP Dried aluminium magnesium polyhydroxy complex USP: magaldrate tablet

ACIDROX-M Tab. Syntho

Dose: 1-2 tablets 3 or 4 times daily half to 1 hour after or between meals & at bedtime.150's pack: 150.00 MRP Hydroxy magnesium aluminate or magaldrate USP: magaldrate suspension.

ACIDROX-M Susp. Syntho

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after or between meals and at bedtime.200ml bot: 50.00 MRP

ACINIL Tab. Somatec Dried aluminium hydroxide gel 250mg & magnesium trisilicate 500mg/tablet. Dose: 1-2 tabs chewed half to 1 hour after meals or as required and at bedtime.200's pack: 100.00 MRP

1. ANTACIDS & OTHER ANTI-DYSPEPTIC DRUGS1.1 Antacids 1.2 Antacids with laxative action 1.3 Anti-dyspeptic & Carminatives

Dosage: See under individual preparations. ACEDONE-Z Tab. ZenithDried aluminium hydroxide gel & magnesium hydroxide BP: tablet.

ACINIL Susp. Somatec Aluminiumhydroxide & magnesium trisilicate BP: suspension

Dose: 2-4 tsf half to 1 hour after meals or when required and at bedtime.200m1 bot: 32.00 MRP

ANTACIDS

21,22,23,33

Definition: Antacids are the most useful drugsfor relief of hyperacidity & associated pain. Antacid preparations are weakly basic and consist of metal salts, most commonly aluminium hydroxide, magnesium hydroxide, calcium carbonate, or sodium bicarbonate.

Dose: 1-2 tabs. chewed half to 1 hour after or inbetween meals and at bed time or as required. Child: Not recommended.250's pack:132.50 MRP

ALGEX Tab. DoctorsDried aluminium hydroxide gel & magnesium hydroxide as tablet. Ind: Dyspepsia, hyperacidity, peptic ulcer, gastritis. Cautions: Renal impairment.

ACEDONE-Z Susp. ZenithAluminium hydroxide gel BP & magnesium hydroxide BP: suspension

Dose: 2-4 tsf half to 1 hour after meals or when

Dose: 1-2 tabs. chewed half to 1 hour after or inbetween meals and at bed time or as required.

GASTRO-INTESTINAL DRUGS

QIMP-14 (2)

Child: Not recommended.200's pack: 100.00 MRP Aluminium hydroxide gel 380mg & magnesium hydroxide 125mg/5ml: suspension.

hydroxide BP: suspension.

ALGEX Susp. Doctors

Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time.200ml bot: 31.80 MRP

BLUMEX Tab. JalalabadDried aluminium hydroxide gel BP 250mg & magnesium hydroxide BP 400mg/tablet

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after or inbetween meals and at bedtime.200ml bot: 32.30 MRP

ANTANIL Tab. Ibn Sina Driedaluminium hydroxide gel BP 250mg & magnesium hydroxide BP 400mg/tablet.

Dose: 1-2 tabs. chewed half to 1 hour after meals or as required & at bedtime.200's pack: 100.00 MRP

BLUMEX Susp. JalalabadAluminium hydroxide gel BP 175mg & magnesium hydroxide BP 225mg/5ml: suspension

ALIDEX Tab. Rasa PharmaDried aluminium hydroxide gel & magnesium hydroxide as tablet. Adults: 1-2 tabs. chewed half to 1 hour after or inbetween meals and at bed time or as required. Child: not recommended. 200's pack: 100.00 MRP

Dose: 2-4 tabs chewed or sucked with water half to 1 hour after meals or as reqd. Child, over 6 yrs. half adult dose.200's pack: 90.00 MRP

ANTANIL Susp. Ibn SinaAlum.hydroxide gel 200mg & magnesium hydroxide 400mg/5ml: suspension.

Dose: 2-4 tsf half to 1 hour after meals and at bedtime or as required.200m1 bot: 32.55 MRP Aluminium hydroxide compressed gel BP 1.875gm & magnesium hydroxide BP 0.4gm/5ml: suspension

COSMACID Susp. Cosmic

ALIDEX Susp. Rasa PharmaAluminium hydroxide compressed gel BP & magnesium hydroxide BP: suspension.

Dose: 1-2 tsf 3 or 4 times daily half to 1 hour after or inbetween meals & at bedtime.200ml bot: 30.85 MRP

ANTANIL Plus Tab. Ibn SinaDried aluminium hydroxide 400mg, magnesium hydroxide 400mg & simethicone (activated dimethicone) 30mg/tablet.

Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time.200m1 bot: 29.00 MRP

Dose: 2-4 tsf half to 1 hour after meals and at bedtime or as reqd.200ml bot: 31.00 MRP

CYTOCI D Tab. CPLAluminium hydroxide dried gel. 300mg, magnesium hydroxide 100mg per tablet.

ALIMAG Tab. AsiaticDried aluminium hydroxide gel & magnesium hydroxide BP: tablet.

Dose: 1-2 tabs. chewed half to 1 hour after meals or as required & at bedtime100's pack: 76.00 MRP Aluminium hydroxide gel 400mg, magnesium hydroxide 400mg & simethicone 30mg/5ml: suspension.

Adults: 1-2 tabs. chewed half to 1 hour after or inbetween meals and at bed time or as required. Child: not recommended.200's pack: 100.00 MRP Dried aluminium hydroxide gel & magnesium hydroxide BP: tablet.

ANTANIL Plus Susp. Ibn Sina

Dose: 1-2 tabs half to 1 hour after meals and at bedtime or as required.200's pack: 100.00 MRP

ALMAG Tab. Proteety

Dose: 2-4 tsf. half to 1 hour after meals or when required & at bedtime.200ml hot: 45.00 MRP Dried aluminium hydroxide gel BP 250mg & magnesium hydroxide BP 400mg/tablet.

C Y T O CI D S u s p . C P L Aluminium hydroxide gel 300mg, magnesium hydroxide 100mg in 5ml: Suspension Dose: 2-4 tsf half to 1 hour after meals and at bedtime or as required.200ml hot: 32.00 MRP

Adults: 1-2 tabs. chewed half to 1 hour after or inbetween meals and at bed time or as required. Child: not recommended.200's pack: 106.00 MRP Aluminium hydroxide gel 250mg, magnesium trislicate 500mg in 5ml: suspension.

APCOCID Tab. Supreme

DEOJEX Tab. Desh PharmaDried aluminium hydroxide gel 250mg & magnesium hydroxide 400mg: tablet

Dose: 2-4 tabs chewed or sucked with water half to 1 hour after meals or as regd. Child, over 6 yrs. half adult dose.100's pack: 50.00 MRP Aluminium hydroxide gel BP & magnesium hydroxide BP: suspension

ALUCIL Susp. Opsonin

Dose: 2-4 tabs. chewed or sucked with water half to 1 hour after meals or as regd. Child, over 6 yrs. half adult dose.200's pack: 100.00 MRP Dried aluminium hydroxide gel BP & magnesium hydroxide BP: tablet

APEDROX Susp. A.P.0 Pharma

DIGEL Tab. Aristopharma

Dose: 2-4 tsf.half to 1 hour after meals and at bedtime.200ml hot: 32.00 MRP Aluminium hydroxide gel 250mg, mag. trisilicate 500mg & simethicone 30mg/5ml: Suspension

Dose: 2-4 tsf half to 1 hour after meals and at bedtime or as required200m1 bot: 30.00 MRP

ALUCIL-S Susp. Opsonin

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after meals and at bedtime or as required.200's pack: 100.00 MRP Aluminium hydroxide gel BP & magnesium hydroxide BP: suspension

Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time.200 ml bot: 45.50 MRP

AVLOCID Tab. ACI Dried aluminium hydroxide 400mg, magnesium hydroxide 400mg & simethicone (activated dimethicone) 30mg/tablet. Dose: 1-2 tabs. chewed half to 1 hour after meals or as required & at bedtime250's pack: 225.00 IP

DIGEL Susp. Aristopharma

ALUGEL Tab. CosmicDried aluminium hydroxide gel BP 250mg & magnesium hydroxide BP 400mg /tablet.

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime or as required.200ml hot: 32.00 MRP

AVLOCID Susp. ACIAluminium hydroxide gel 400mg, magnesium hydroxide 400mg & simethicone 30mg/5ml: suspension.

DOLOCID Tab. Aexim PharmaAlum. trisilicate dried gel BP, mag. trisilicate BP: tablet.

Adults: 1-2 tabs. chewed half to 1 hour after or inbetween meals and at bed time or as required.200's pack: 100.00 MRP Aluminium hydroxide gel BP & magnesium hydroxide BP: suspension

ANCIDPLUS DS Susp. Renata

Dose: 2-4 tsf. half to 1 hour after meals or when required & at bedtime.200ml bot: 50.00 IP

Dose: 2-4 tabs chewed or sucked with water half to 1 hour after meals or as reqd. Child, over 6 yrs. half adult dose.200's pack: 86.00 MRP

Dose: 2-4 tsf half to 1 hour after meals and at bedtime or as required.200ml bot: 46.02 MRP

BIOCID Tab. Bio-PharmaDried aluminium hydroxide gel BP & magnesium hydroxide BP: tablet

DOLOCID Susp. Aexim PharmaAluminium hydroxide gel BP & magnesium hydroxide BP: syrup

ANTAMEAL Tab. Alco PharmaDried aluminium hydroxide gel & magnesium hydroxide BP: tablet

Dose: 1-2 tabs. chewed half to 1 hour after meals or as required & at bedtime.200's pack: 90.00 MRP

Dose: 1-2 tsf 3 or 4 times daily half to 1 hour after or inbetween meals & at bedtime.200m1 bot: 32.00 MRP

Dose: 2-4 tabs. chewed or sucked with water half to 1 hour after meals or as regd. Child, over 6 yrs. half adult dose.200's pack: 100.00 MRP Alumin hydroxide gel BP & magnesium

BIOCID MH Susp. Bio-PharmaAluminium hydroxide gel BP & magnesium hydroxide BP: suspension

DROXIGEL-Plus Tab. ModernDried aluminium hydroxide BP 400mg, magnesium hydroxide BP 400mg & simethicone 30mg/tablet.

ANTAMEAL Susp. Alco Pharma

Dose: 2-4 tsf half to 1 hour after meals and at bedtime or as required200ml bot: 32.30 MRP

Dose: 1-2 tablets chewed half to 1 hour after meals & at bed time.

QIMP-14 (3)

GASTROINTESTINAL DRUGS

200's pack: 158.00 MRP DROXIGEL-S Susp. Modern Aluminium hydroxide gel BP 2.00gm & magnesium hydroxide paste BP 334mg/5ml: suspension. Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time. 200ml bot: 32.88 MRP DROXIGEL-Plus Susp. Modern Aluminium hydroxide gel BP 2.00gm, magnesium hydroxide BP paste 1330mg & simethicone 30mg/5ml: suspension. Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time. 200m1 bot: 55.00 MRP E-ANTACID Tab. Elixir Dried aluminium hydroxide gel BP & magnesium hydroxide BP: tablet. Dose: 1-2 tabs. half to 1 hour after or between meals and at bedtime. 200's pack: 106.00 MRP ENTACYD Tab. Square Dried aluminium hydroxide gel BP 250mg, magnesium hydroxide BP 200mg & magnesium trisilicate 370mg/tablet. Dose: 1-2 tabs. half to 1 hour after or between meals and at bedtime. 200's pack: 106.00 MRP ENTACYD Susp. Square Aluminium hydroxide gel BP. 250 mg, magnesium hydroxide BPC 125mg in 5ml: suspension Dose: 2-4 tsf half to 1 hour or between meals and at bedtime. 200m1 bot: 32.37 MRP ENTACYD Plus Tab. Square Dried alumin. hydroxide gel BP & magnesium hydroxide BP + Simethicone 30mg/tablet. Dose: 1-2 tabs. chewed half to 1 hour after meals & at bed time. 200's pack: 180.00 MRP ENTACYD Plus Susp. Square Aluminium hydroxide gel BP & magnesium hydroxide BP + simethicone 30mg/5ml: suspension. Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time. 200m1 bot: 55.00 MRP EPAZEL Susp. Edruc Aluminium hydroxide gel BP & magnesium hydroxide BP: suspension (sugar free). Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time. 200m1 hot: 32.00 MRP FLATAMEAL- DS Tab. Beximco Dried aluminium hydroxide gel BP & magnesium hydroxide BP + Simethicone 30mg/tablet. Ind: Dyspepsia, hyperacidity, peptic ulcer, flatulence. Dose: 1-2 tabs. chewed half to 1 hour after meal or as required & at bedtime 200's pack: 180.00 MRP FLATAMEAL-DS Susp. Beximco Alumin. hydroxide gel & magnesium hydroxide BP + Simethicone 30mg/5ml: suspension. Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time. 200m1 bot: 50.00 MRP G-ANTACID Tab. Gonoshasthaya Dried aluminium hydroxide gel 250mg &

magnesium trisilicate 500mg + mannitol 120mg/tablet. Dose: 1-2 tabs chewed or sucked with water half to 1 hour after meals or when required. 250's strip pack: 125.00 MRP 1000's pot: 300.00 MRP G-ANTACID Susp. Gonoshasthaya. Aluminium hydroxide gel 125mg & magnesium trisilicate 500mg in 5ml: suspension Dose: 2-4 tsf half to 1 hour after or between meals and at bedtime. 200ml bot: 25.00 MRP G-ANTACID MH Tab. Gonoshasthaya Dried aluminium hydroxide gel & magnesium hydroxide BP: tablet. Dose: 1-2 tabs chewed or sucked with water half to 1 hour after meals or when required. 200's pack: 100.00 MRP GASCON Tab. Popular Dried alumin. hydroxide gel BP 400mg & magnesium hydroxide BP + Simethicone 30mg/tablet. Dose: 1-2 tabs. chewed half to 1 hour after meals & at bed time. 200's pack: 180.00 IP GASCON Susp. Popular Aluminium hydroxide gel BP 200mg & magnesium hydroxide BP 400mg + simethicone 30mg/5ml: suspension. Dose: 2-4 tsf half to 1 hour after meals or when required & at bed time. 200ml bot: 55.00 IP GASTOLIN Susp. Belsen Aluminium hydroxide gel & magnesium trisilicate BP: suspension Dose: 2-4 tsf half to 1 hour after or between meals and at bedtime. 200ml bot: 30.00 MRP GASTRODYNE Tab. Orion Dried aluminium hydroxide gel & magnesium hydroxide BP: tablet. Dose: 1-2 tabs. chewed half to 1 hour after meals and at bedtime. 200's pack: 100.00 MRP GASTRODYNE Susp. Orion Aluminium hydroxide gel & magnesium hydroxide BP: suspension Dose: 2-4 tsf half to 1 hour after meals and at bedtime. 200ml bot: 30.00 MRP GASTROX MH Tab. Pharmaco Inter. Aluminium hydroxide dried gel: tablet 100's pack: 50.58 MRP GASTROX MH Susp. Pharmaco Inter. Aluminium hydroxide compressed gel: suspension Dose: 2-4 tsf half to 1 hour after meal and at bedtime. 200ml bot: 30.34 MRP GELUDROX-HS Tab. Drug Inter Aluminium hydroxide dried gel. BP. 250mg, mag. trisilicate 500mg & simethicone 30mg/tablet Dose: 1-2 tabs half to 1 hour after meals or when reqd. 120's pack: 94.80 MRP GELUDROX HS Susp. Drug Inter Aluminium hydroxide compressed gel. BP equivalent to alum. oxide 200mg, magnesium hydroxide BP 400mg & simethicone 30mg/5ml: suspension

Dose: 2-4 tsf half to 1 hour after meal and at bedtime. 200ml bot: 55.00 MRP HI-GEL Tab. Hudson Dried aluminium/magnesium hydroxide BP prepn: antacid tablet. Dose: 1-2 tabs half to 1 hour after meals or when required. 200's pack : 104.00 MRP HI-GEL Susp. Hudson Aluminium hydroxide gel BP + magnesium hydroxide BP: suspension Dose: 2-4 tsf half to 1 hour after meals 3 or 4 times daily and at bedtime. 200ml bot: 32.00 MRP HYDROCID Tab. Millat Dried aluminium hydroxide gel + magnesium hydroxide BP prepn: antacid tablet Dose: 1-2 tabs. chewed half to 1 hour after meals and at bedtime. 200's pack: 106.00 MRP HYDROCID Susp. Millat Aluminium hydroxide gel BP + magnesium hydroxide BP: suspension Dose: 2-4 tsf half to 1 hour after meals and at bedtime. 200ml bot: 32.20 MRP JPDROX Tab. Jayson Dried aluminium hydroxide gel + magnesium hydroxide BP prepn: antacid tablet Dose: 1-2 tabs half to 1 hour after meals or when required. 200's pack: 106.00 MRP JPDROX Susp. Jayson Aluminium hydroxide gel BP 425mg, magnesium hydroxide BPC 425mg per 5ml : suspension. Dose: 2-4 tsf half to 1 hour after meals 3 or 4 times daily and at bedtime. 200ml bot: 32.36 MRP JPDROX-S Tab. Jayson Dried aluminium hydroxide gel + magnesium hydroxide BP + Simethicone: antacid tablet Dose: 1-2 tabs half to 1 hour after meals or when required. 100's pack: 76.00 MRP JPDROX-S Susp. Jayson Aluminium hydroxide gel BP 425mg + magnesium hydroxide BPC 425mg + simethicone 30mg per 5ml : suspension. Dose: 2-4 tsf half to 1 hour after meals 3 or 4 times daily and at bedtime. 200ml bot: 42.48 MRP KAMODROX Tab. Chemico Dried aluminium hydroxide gel BP 250mg & magnesium hydrox BP 400mg /tablet. Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after meals and at bedtime. 200's pack: 100.00 MRP KAMODROX Susp. Chemico Aluminium hydroxide compressed gel 185mg & magnesium hydroxide 100mg in 5ml: suspension Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime. 200m1 bot: 32.00 MRP LACTAMEAL Tab. Beximco Dried aluminium hydroxide gel BP 200mg, magnesium hydrox BP 200mg per tablet. Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after meals and at bedtime. 200's pack: 106.00 MRP

GASTROINTESTINAL DRUGS

QIMP-14 (4)

Aluminium hydroxide gel. BP125mg, magnesium hydroxide BP 225mg in 5m1

LACTAMEAL Susp. Beximco

Aluminium hydroxide compressed gel + magnesium hydroxide paste: antacid suspension

preparation

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml bot: 32.37 MRP

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml bot: 31.68 MRP

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after or between meals and at bedtimes.200ml bot: 54.00 MRP

OXECONE-S Susp. AcmeAlumin. hydroxide gel 400mg & magnesium hydroxide 400mg USP + simethicone 30mg/5 ml: suspension.

NEUTRAL-S Tab. HallmarkDried aluminium/magnesium hydroxide gel prepn with simethicone: antacid tablet

MAGADRATE-Plus Tab. AeximDried aluminium magnesium polyhydroxy complex USP & magnesium carbonate: magaldrate preparation

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after meals and at bedtime.200's pack: 156.00 MRP Aluminium hydroxide compressed gel + magnesium hydroxide paste + simethicone: antacid suspension

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200 ml bot: 50.00 MRP

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after or between meals & at bedtime.100's pack: 80.00 MRP Hydroxy magnesium aluminate or magaldrate 444mg/5ml USP: magaldrate suspension. Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after or between meals and at bedtime. 200ml bot: 50.00 MRP

NEUTRAL-S Susp. Hallmark

PEPTACID Tab. AmicoDried aluminium/magnesium hydroxide gel preparation with simethicone: antacid tablet Ind: Dyspepsia, hyperacidity, peptic ulcer, flatulence.

MAGADRATE-Plus Susp. Aexim

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml bot: 45.50 MRP

Dose: 1-2 tablets 3 or 4 times daily half to 1 hour after meals & at bedtime.100's pack: 70.00 MRP

NOCID Tab. MedimetAntacid preparation: tablet

MAGADROX Plus Tab. GacoAluminium hydroxide dried gel 250mg, mag. trisilicate 400mg + Simethicone 30mg/tablet.

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after or between meals & at bedtime.200's pack: 106.00 MRP

Dose: 1-2 tabs half to 1 hour after meals or when required.100's pack: 79.50 MRP Aluminium hydroxide gel. BP, magnesium hydroxide BP & simethicone 30mg/5ml.: Suspension

PEPTACID Susp. Amico Aluminium hydroxide & magnesium hydroxide gel + simethicone 30mg/5ml: antacid suspension Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime. 200ml bot: 40.00 MRP PEPTOSOL-MH Tab. Globe PharmaDried aluminium hydroxide gel BP + magnesium hydroxide BP: tablet.

NOCID Plus Tab. MedimetAntacid preparation with simethicone: tablet

MAGADROX Plus Susp. Gaco

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after or between meals & at bedtime.200's pack: 158.00 MRP Antacid liquid prepn: suspension.

Dose: 2-4 tsf half to 1 hour after meal and at bedtime.200ml bot: 46.02 MRP Aluminium magnesium polyhydroxy complex or magaldrate usp 444mg/5ml: suspension

NOCID-N Susp. Medimet

Dose: 1-2 tabs. chewed or sucked with water half to 1 hour after or between meals and at bedtime.100's pack: 50.00 MRP Aluminium hydroxide compressed gel 187.5mg + magnesium hydroxide 200mg/5ml: suspension.

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime or as required.200ml bot: 32.50 MRP Aluminium hydroxide compressed gel + magnesium hydroxide paste + simethicone: antacid suspension

MAGAPLUS Susp. Chemico

PEPTOSOL-MH Susp. Globe Pharma

NOCID Plus Susp. Medimet

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after or between meals and at bedtime.200ml bot: 50.00 MRP

Dose: 2-4 tsf half to 1 hour after or between meals and at bedtime.200ml bot: 32.00 MRP

MAGNOGEL Tab. AmicoDried aluminium/magnesium hydroxide BP prepn: antacid tablet

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200m1 bot: 45.00 MRP

PEPTOSOL-DS Susp. Globe PharmaAluminium hydroxide compressed gel 200mg + magnesium hydroxide 400mg+ simethicone 30mg/5ml: antacid suspension

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after meals and at bedtime.200's pack: 100.00 MRP Aluminium hydroxide & magnesium hydroxide gel prepn: antacid suspension

OXECONE Tab. AcmeDried alumn. hydroxide gel 250mg & magnesium hydroxide 400mg/tablet

MAGNOGEL Susp. Amico

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after or between meals & at bedtime.100's pack: 53.00 MRP

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200m1 bot: 45.00 MRP

PHARMACID Susp. PharmadeshAluminium hydroxide gel BP 200mg + magnesium hydroxide BP 125mg/ 5ml: suspension

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml bot: 32.00 MRP Dried aluminium magnesium polyhydroxy complex USP & magnesium carbonate: magaldrate preparation

OXECONE-M Tab. AcmeDried aluminium magnesium polyhydroxy complex USP & magnesium carbonate: magaldrate preparation

MARLOX Tab. Incepta

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after or between meals & at bedtime.100's pack: 100.00 MRP

Dose: 2 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200m1 bot: 27.35 MRP

PHARMACID Plus Tab. PharmadeshDried aluminium hydroxide gel. BP 400mg & magnesium hydroxide BP 400mg + simethicone 30mg/tablet.

Dose: 1-2 tablets by chewing half to 1 hour after meals or when required.200's pack: 200.00 MRP Aluminium hydroxide & magnesium hydroxide gel prepn: antacid suspension

OXECONE-S Tab. AcmeDried alumn. hydroxide gel 400mg & magnesium hydroxide 400mg + simethicone 30mg/tablet Ind: Dyspepsia, hyperacidity, peptic ulcer, flatulence.

MUCOGEL Susp. Medicon

Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after meals and as required.200's pack: 156.00 MRP

Dose: 1-2 tabs chewed half to 1 hour after meal or as required & at bedtime.100's pack: 90.00 MRP Aluminium hydroxide compressed gel 200mg & magnesium hydroxide 125mg/5ml: Suspension

PHARMACID Plus Susp. PharmadeshAluminium hydroxide compressed gel 200mg + magnesium hydroxide 400mg+ simethicone 30mg/5ml: antacid suspension

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200m1 bot: 32.00 MRP

OXECONE Susp. Acme

NEUTRAL Tab. HallmarkDried aluminium/magnesium hydroxide gel prepn: antacid tablet Dose: 1-2 tabs 3 or 4 times daily half to 1 hour after meals and at bedtime or as required 200's pack: 100.00 MRP

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals & at bedtime.200ml bot: 32.00 MRP

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml bot: 43.00 MRP

PLACID Tab. SaltonDried aluminium hydroxide BP + magnesium hydroxide BP: tablet.

NEUTRAL Susp. Hallmark

Aluminium magnesium polyhydroxy complex USP & magnesiumcarbonate: magaldrate

OXECONE-M Susp. Acme

Dose: 1-2 tabs chewed or sucked with water

QIMP-14 (5)

GASTROINTESTINAL DRUGS

half to 1 hour after or between meals and at bedtime.200's pack: 110.00 MRP Antacid liquid prepn. BP: suspension

Aluminium hydroxide gel 400 mg + magnesium hydroxide 400mg/5ml: suspension

SKYCID-T Susp. Skylab

PLACID Susp. Salton

Dose: 2-4 tsf half to 1 hour after or between meals and at bedtime.200m1 bot: 32.50 MRP

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml bot: 32.00 MRP RECOCID Tab. Rephco Dried aluminium hydroxide gel & magnesium hydroxide BP: tablet. Dose: 1-2 tabs chewed or sucked with water half to 1 hour after or between meals and at bedtime. 200's pack: 100.00 MRP Aluminium hydroxide gel & magnesium trisilicate BP: antacid suspension

STOMA Tab. SK+FDried aluminium hydroxide 250mg + magnesium hydroxide 400mg/tablet. 200's pack: 107.22 MRP

STOMACID Tab. AmbeeDried aluminium hydroxide BP + magnesium hydroxide BP: tablet.

constipating aluminium salt. Ind: Constipation, heart-burn, gas & nausea. Acute & chronic constipation due to hyperacidity & peptic ulcer. C/I: Do not use where use fo laxative is contraindicated; acute gastro-intestinal conditions; renal failure (risk of magnesium accumulation). S/E: Diarrhoea; abdominal colic. Caution: Hepatic impairment elderly and debilitated; heart block, myocardial disease; pregnancy.

RECOCID Forte Susp. Rephco

Dose: 1-2 tabs chewed or sucked with water half to 1 hour after or between meals and at bedtime.100's pack: 53.00 MRP

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200 ml hot: 32.90 MRP

STOMACID Susp. AmbeeAluminium hydroxide gel B. P + Magnesium hydroxide BP: suspension

Doses: Adults & older children: 5 to 10 tsf in a single dose or in divided doses with a glass of water. Children: 6-11 years, 3 to 5 tsf in a single dose or in divided doses with water; 2-5 years, 1 to 3 tsf in a single dose or in divided doses with water. ACME'S MILK OF MAGNESIA Susp. Acme Magnesium hydroxide BP. 400mg/5ml:suspension 114m1 bot: 13.14 MRP

REMACID Plus Tab. RemanAntacid prepn. + Simethicone: tablet

Dose: 2-4 tsf 3 to 4 times daily half to 1 hour after meals and as required.200ml bot: 32.87 MRP

Dose: 1-2 tabs chewed 3-4 times daily half to 1 hour after meals and as required.200's pack: 156.00 MRP

SUGEL Tab. PacificDried aluminium hydroxide BP + magnesium hydroxide BP: tablet.

MAGMIL Susp. PacificMagnesium hydroxide BP. 400mg/5ml: suspension 100ml bot: 28.00 MRP 200ml hot: 50.00 MRP

REMACID Susp. RemanAntacid liquid prepn. BP: suspension

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml hot: 32.00 MRP

Dose: 1-2 tabs chewed or sucked with water half to 1 hour after or between meals and at bedtime.200's pack: 100.00 MRP Aluminium hydroxide gel B. P + Magnesium hydroxide BP: suspension

MAGNASON Susp. JaysonMagnesium hydroxide BP. 400mg/5ml: suspension 100m1 bot: 12.50 MRP

REMACID Plus Susp. RemanAntacid liquid prepn. BP + simethicone: suspension

SUGEL Susp. Pacific

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml bot: 45.50 MRP

Dose: 2-4 tsf 3 to 4 times daily half to 1 hour after meals and as required.200ml bot: 32.00 MRP

MILK OF MAGNESIA-AL Susp. AeximMagnesium hydroxide BP. 400mg/5ml: suspension 114m1 bot: 12.00 MRP

SEEMACID Tab. SeemaDried aluminium hydroxide gel BP + magnesium hydroxide BP: tablet.

TRICID Tab. KumudiniDried aluminium/magnesium hydroxide BP prepn: antacid tablet

MILK OF MAGNESIA Susp. DoctorsMagnesium hydroxide BP 412mg/5ml: suspension 114ml bot: 13.00 MRP

Dose: 1-2 tabs chewed or sucked with water half to 1 hour after or between meals and at bedtime.200's pack: 100.00 MRP Aluminium hydroxide gel BP: suspension

Dose: 1-2 tabs half to 1 hour after meals or when required.200's pack: 100.00 MRP Aluminium hydroxide gel BP + magnesium hydroxide BP: suspension

MILK OF MAGNESIA Susp. GacoMagnesium hydroxide BP: suspension. 100ml bot: 12.61 MRP

TRICID Susp. Kumudini

SEEMACID-MH Susp. Seema

MILK OF MAGNESIA Susp. MillatMagnesium hydroxide BP: suspension. 100m1 bot: 15.17 MRP

Dose: 2-4 tsf 3 times daily half to 1 hour after meals and as required.200ml bot: 32.00 MRP Antacid liquid prepn. BP + simethicone: suspension

Dose: 2-4 tsf half to 1 hour after meals 3 or 4 times daily and at bedtime.200m1 bot: 32.00 MRP

MILK OF MAGNESIA Susp. ModernMagnesium hydroxide BP 8% w/w: suspension. 100ml bot: 15.00 MRP

SEEMACID Plus Susp. Seema

Z-ANTACID Tab. ZiskaDried aluminium hydroxide gel BP + magnesium hydroxide: tablet

MILK OF MAGNESIA Susp. OrionMagnesium hydroxide BP: suspension. 100ml bot: 11.45 MRP

Dose: 2-4 tsf 3 or 4 times daily half to 1 hour after meals and at bedtime.200ml bot: 45.50 MRP

Dose: 1-2 tabs. chewed 3 times daily half to 1 hour after meals and as required.200's pack: 70.00 MRP

MILK OF MAGNESIA Susp. PharmadeshMagnesium hydroxide suspension 100ml bot: 14.00 MRP

SIMGEL Susp. OrionAluminium oxide 200mg (equivalent amount of aluminium hydroxide gel USP), magnesium hydroxide 400mg (equivalent amount of magnesium hydroxide paste USP) & simethicone USP 30mg/5ml: Suspension

Antacids with Laxative actionMAGNESIUM HYDROXIDE21,22,23,33

MILK OF MAGNESIA Susp. SeemaMagnesium hydroxide suspension 114ml hot: 13.00 MRP MOM Susp. Opsonin Magnesium hydroxide (milk of magnesia) suspension 114ml bot: 13.00 MRP

Dose: 1-2 tsf 1 hour after meal and at bedtime or as directed by the physician.200ml bot: 50.00 MRP

MAGNESIUM HYDROXIDE OR MILK OF MAGNESIA: Suspension Composition & action: An aqueous suspensionof magnesium hydroxide containing about 8% hydrated magnesium oxide, also known as milk of magnesia is an effective osmotic laxative. This magnesium salt is useful where rapid bowel evacuation is required & acts as an osmotic laxative by retaining water within the gut. This is also an effective antacid and bowel disturbances are minimized when combined with potentially

Anti- dyspeptic & CarminativesSIMETHICONE26,42

SKYCID-T Tab. SkylabDried aluminium hydroxide BP + magnesium hydroxide BP: tablet.

Dose: 1-2 tabs chewed or sucked with water half to 1 hour after or between meals and at bedtime.200's pack: 104.00 MRP

SIMETHICONE : Drop

Simethicone is an effective antiflatulent. It is used for relief of the painful symptoms of excess

GASTROINTESTINAL DRUGS

QIMP-14 (6)

gas in the digestive tract. Such gas is frequently caused by excessive swallowing of air or by eating foods that disagree, or leading to indigestion. Mode of action: Simethicone acts in the stomach and intestines to change the surface tension of gas bubbles, enabling them to coalesce, thus gas is freed and eliminated more easily by belching or passing flatus. Its defoaming action relieves flatulence by dispersing and preventing the formation of mucous surrounded gas pockets in the G.I tract. Ind: 1. Flatulence, abdominal distention, fullness, gas and windy colic. Simethicone drop is specially used in infants. 2. Postoperative gas pains- simethicone aids in the elimination of gas from the GI tract and can be used to reduce postoperative gas pains. 2. Large bowel preparation- addition of simethicone to a polyethylene glycol bowel preparation produces symptomatic improvement prior to investigation in patients undergoing colonoscopy. 3. Treatment of poisoning- simethicone has an anecdotal use as an antifoaming agent in the management of accidental ingestion of foaming detergents. C/I: Contra-indicated in renal failure, severely debilitated patients, 1st trimester of pregnancy. S/E: Simethicone is physiologically inert and no adverse effect has been noted after oral ingestion. Precaution: Do not exceed 12 doses per day except under the advice and supervision of a physician. Keep the medicine out of the reach of children. Pregnancy & Lactation: No data are available to suggest any harmful effect in pregnancy, still it is not advised to give in the 1st trimester. Excretion of simethicone in breast milk has not been established, and is also unlikely.

15ml drop: 30.00 MRP

LEFOAM Drop InceptaSimethicone USP 67mg/ml: drop 15ml drop: 30.00 MRP

S/E: Dry mouth with difficulty in swallowing &thirst, dilatation of pupils with loss of accommodation and sensitivity to light, increased intraocular pressure, flushing, dry skin, bradycardia, followed by tachycardia, palpitations and arrhythmias, difficulty with micturition and constipation. Cautions: Elderly patient; urinary retention, tachycardia, cardiac insufficiency; and during breast feeding.

NEODROP Drop BeximcoSimethicone USP 67mg/ml: drop 15ml drop: 30.00 IP

PEDICON Drop OrionSimethicone USP 67mg/ml: drop 10ml drop: 25.00 MRP 20ml drop: 30.00 MRP Simethicone USP 67mg/ml: drop 15ml drop: 30.00 MRP Simethicone USP 67mg/ml: drop 15ml drop: 28.00 MRP

SEMECON Drop Drug Inter.

Dose: By mouth, 0.25-2 mg daily in single or divided doses, dosage should be gradually increased to the max. tolerated. By inj. 0.25-2 mg sC or i.m. injection. ATROPINE-Jayson Inj. Jayson ATROPINE Sulph. Inj. Edruc

SIMECOL Drop Alco PharmaAtropine sulphate 0.6mg/1ml ampoule: injection 10 amps pack: 31.90 IP Atropine sulphate 0.6mg/1ml ampoule: injection 10 amps pack: 30.00 IP

SIMICON Drop NavanaSimethicone USP 67mg/ml: drop 15ml drop: 30.00 MRP

CARMINATIVE PREPNS.21,38CARMINATIVE MIXTURE: LiquidSodium bicarbonate, chloroform, Tr. gingb. fort, Menthapip, Peppermint, Camphor, Tr. card Co. Ind: Dyspepsia, hyperacidity, indigestion, gas formation in the stomach & intestine.

G-ATROPINE Sulph. Inj. Gonoshas.Atropine sulphate 0.6mg/1ml ampoule: injection 10 amps pack: 30.00 MRP

MYDRIPINE Inj. GacoAtropine sulphate 0.6mg/1ml ampoule: injection 1 ampoule: 2.62 MRP

Dose: 1 tablespoonful diluted with water 3 times daily or when required. Preparation: May be available in the pharmaciesas mixture.

BELLADONAALKALOID

21,39

SODA MINT Tablet.Sodium bicarbonate 300mg, contains about 4 mmol Na+/tablet. Ind: Rapid relief of dyspepsia. Cautions: Renal impairment; patient on a sodium-restricted diet; avoid prolonged use. S/E: Belching, alkalosis etc.

BELLADONA ALKALOIDS: Tablet/ Suspension /Powder/ Tincture. Ind: Peptic ulceration, pylorospasm, hypersecretions, g.i spasm, renal and biliary colic,irritable bowel syndrome. C/1; S/E; Cautions: See under atropine sulphate.

Belladona alkaloid BP as tincture

TR. BELLADONA Jayson

Dosage & Admin: Children less than 2 years of age- 20mg (0.3ml or 5 drops) 4 times daily up to 240mg (3.6ml or 55 drops)/day. Children 2-12 years of age- 40mg (0.6m1 or 10 drops) 4 times daily. Adults- 40-80mg (0.6ml-1.2ml or 10-20 drops) 4 times daily, up to 500mg (7.5ml)/day. Take all the dosages after meals and at bedtime. Incase of infants, can be given with feeds. Shake the bottle well before each use. Durg inter: There is no evidence that simethiconemodifies the effect of other drugs. The defoaming effect of simethicone is reduced by antacids such as aluminium hydroxide and magnesium carbonate, which absorb the silicone.

Dose: 2-6 tablets sucked when required.

2. ANTISPASMODICS (Anticholinergics)2.1 Antimuscarinics a) Tertiary amines viz: Atropine sulphate, Dicycloverine (Dicyclomine) hydrochloride b) Quaternary ammonium compounds viz: Hyoscine butylbromide, Propantheline 2.2 Other antispasmodics viz: Alverine citrate, Drotaverine, Mebeverine, Oxyphencyclimine, Oxyphenonum bromide, Timonium etc.

Adult: 2-4 tsf 3 times daily. Child: 1-2 tsf 3 times daily 1/2 hour before or between meals.450m1 bot: 161.83 MRP26,42

DICYCLOVERINE

DICYCLOVERINE HCI: Tablet/SyrupDicycloverine hydrochloride is an antimuscarinic (anticholinergic) antispasmodic agent, used to relieve smooth muscle spasm of the gastrointestinal tract. It is available as dicycloverine hydrochloride BP 10mg/tablet and 10mg/5ml syrup. Mode of action: It works at specific receptors, called cholinergic (or muscarinic) receptors, located on the involuntary muscles in the walls of the gut. By binding to these receptors dicycloverine prevents certain chemicals produced by the body from interacting with these receptors. This causes the gut muscle to relax, relieving the pain of colic produced by gut muscle contraction and spasm. Ind: i. Functional or irritable bowel syndrome, ii. urinary incontinence secondary to unstable detrusor muscle, iii. infantile colic, iv. gastrointestinal spasm, v. colicky abdominal pain, vi. diverticulitis, and vii. abdominal colic. C/I: i. Obstructive uropathy, ii. obstructive disease of the gastrointestinal tract, iii. severe ulcerative colitis, iv. reflux esophagitis, v. unstable

AntimuscarinicsATROPINE SULPHATEAEROPAC Drop AmicoSimethicone USP 67mg/ml: drop 15ml drop: 25.00 MRP Simethicone USP 67mg/ml: drop21,33

ATROPINE SULPHATE: Tablet/ Injection. Ind: Aid in peptic ulcer treatment, g.i spasm,renal & biliary colic. C/I: Glaucoma, paralytic ileus, pyloric stenosis, prostatic enlargement, intestinal obstruction.

FLACOL Drop Square

QIMP-14 (7)

GASTROINTESTINAL DRUGS

cardiovascular status in acute hemorrhage, vi. glaucoma, vii. myasthenia gravis, viii. evidence of prior hypersensitivity to dicycloverine hydrochloride or other ingredients of this formulation, and ix. infants less than 6 months of age. S/E: Insomnia, mydriasis, cycloplegia, increased ocular tension, urinary hesitancy, palpitations, dyspnea. Precaution: Use with caution in patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis, coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, hiatal hernia, known or suspected prostatic hypertrophy. Pregnancy & lactation: Dicycloverine was neither teratogenic nor embryocidal in animal trial. However, in human pregnancy it should be used only if clearly needed. There are evidences on the secretion of dicycloverine into breast milk. So, it should not be used in case of lactating mother.42 Dosage & admin: By mouth: Adults- 10 to 20mg 3 times a day. Maximum recommended, oral dose is 160mg daily in divided doses. Children over 6 months of age- 5 to 10mg 3 times a day. By i.m injection: Usual recommended dose is 80mg daily by i.m route in 4 divided doses. Drug inter: The following agents may increase certain actions or side-effects of dicycloverineamantadine antiarrhythmic agents of class (e.g quinidine), antihistamine antipsychotic agents (e.g phenothiazines), benzodiazepines, MAO inhibitors, narcotic analgesics (e.g meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity.

50ml bot: 30.00 MRP DIVERIN Tab. ACI Dicycloverine hydrochloride BP 10mg/tablet 50's pack: 100.00 IP DIVERIN Syp. ACI Dicycloverine hydrochloride BP 10mg/5m1: syrup 50m1 bot: 30.00 IP LOVERIN Tab. Beximco Dicycloverine hydrochloride BP 10mg/tablet 50's pack: 100.00 IP LOVERIN Syp. Beximco Dicycloverine hydrochloride BP 10mg/5ml: syrup 50ml bot: 30.00 IP WINSPA Tab. Apex Dicycloverine hydrochloride BP 10mg/tablet 50's pack: 100.00 MRP WINSPA Syp. Apex Dicycloverine hydrochloride BP 10mg/5ml: syrup 50ml bot: 30.00 MRP

100's pack: 180.00 MRP 500's pack: 900.00 MRP BUTAPAN Tab. Sanofi Aventis Hyoscine butylbromide 10mg & 20mg/tablet. 10mg x 500's pack: 915.00 MRP 20mg x 100's pack: 350.00 MRP BUTAPAN Inj. Sanofi Aventis Hyoscine butylbromide 20mg/1ml ampoule: injection 10 amps pack: 78.60 MRP BUTASON Tab. Hudson Hyoscine butylbromide 10mg/tablet. 100's pack: 175.00 MRP BUTASTAT Tab. Alco Pharma Hyoscine butylbromide 10mg/tablet. 100's pack: 182.00 MRP BUTYL-K Tab. Chemico Hyoscine butylbromide 10mg/tablet. 100's pack: 180.00 MRP BUTYL-20 Tab. Chemico Hyoscine butylbromide 20mg/tablet. 50's pack: 175.00 MRP COLIPAN Tab. Medimet Hyoscine butylbromide 10mg & 20mg/tablet. 10mg x 100's pack: 162.00 MRP 20mg x 50's pack: 175.00 MRP COLIPAN Inj. Medimet Hyoscine butylbromide 20mg/1ml amp: injection 10 amps pack: 74.60 MRP DE-SPASM Tab. Millat Hyoscine butylbromide 10mg/tablet. 100's pack: 180.00 MRP GASTOPAN Tab. Salton Hyoscine butylbromide 10mg/tablet. 100's pack: 150.00 MRP G-HYOSCINE Tab. Gonoshas Hyoscine butylbromide 10mg/tablet. 100's pack: 160.00 MRP G-HYOSCINE Inj. Gonoshas Hyoscine butylbromide 20mg/1ml amp: injection 10 amps pack: 60.00 MRP HYBUCIN Tab. Supreme Hyoscine-butylbromide 10mg/tablet. 100's pack: 160.00 MRP HYLAC Tab. Apollo Hyoscine-butylbromide 10mg/tablet. 100's pack: 181.00 MRP HYO 10 Tab. Somatec Hyoscine butylbromide 10mg/tablet. 100's pack: 160.00 MRP HYOSIN Tab. Delta Hyoscine butylbromide 10mg/tablet. 100's pack: 180.00 MRP H YSI N Ta b . Ed ru c Hyoscine butylbromide 10mg/tablet. 100's pack: 180.00 MRP H YS I N I n j . E d r u c Hyoscine-nbutylbromide 10mg/1ml amp: injection 10 amps pack: 77.50 MRP HYSOCIN Tab. Pharmadesh Hyoscine butylbromide 10mg/tablet. 100's pack: 125.00 MRP HYSOMA Tab. Modern Hyoscine butylbromide 10mg/tablet. 100's pack: 167.00 MRP HYSOMIDE Tab. Opsonin Hyoscine butylbromide 10mg & 20mg/tablet. 10mg x 100's pack: 180.00 MRP 20mg x 100's pack: 350.00 MRP

HYOSCINE BUTYLBROMIDE

21,33

HYOSCINE BUTYLBROMIDE: Tablet/Tincture/ Injction. Ind: Aid in peptic ulcer treatment, spasmodic pain, gastro-intestinal spasm, biliary and spasmodic dysmenorrhoea. C/I; S/E; Cautions: Same as atropine sulphate (above). Dose: By mouth, adult- 20mg 4 times daily. Child- under 6 years not recommended, 6-12 yrs. 10mg 3 times daily. By injection, 20mg i.m. or i.v inj.(in acute pain or spasm), repeated after 30 minutes if necessary. ANCOPAN Tab. Bristol Hyoscine butylbromide BP 10mg & 20mg/tablet 10mg x 100's pack: 180.00 MRP 20mg x 50's pack: 175.00 MRP ANTIPEN Tab. Nipa Hyoscine butylbromide BP 10mg/tablet 100's pack: 162.00 MRP ASIPAN 20 Tab. Asiatic Hyoscine butylbromide BP 20mg/tablet 100's pack: 300.00 MRP B R O MI D Tab . SK +F Hyoscine butylbromide BP 10mg & 20mg/tablet 10mg x 100's pack: 180.00 MRP 20mg x 50's pack: 175.00 MRP BROSPAN Tab. Gaco Hyoscinen- butylbromide BP 10mg/tablet. 100's pack: 181.53 MRP B ROS PAN I nj . Ga co Hyoscine butylbromide 20mg/1ml amp: injection 1 ampoule: 7.84 MRP BUSCOGEN Tab. Skylab Hyoscine butylbromide 10mg/tablet. 100's pack: 145.00 MRP BUSCON Tab. Ibn Sina Hyoscine butylbromide 10mg/tablet. 100's pack: 182.00 MRP BUSCON Inj. Ibn Sina Hyoscine butylbromide 20mg/1ml ampoule: injection 10 amps pack: 70.00 MRP BUTACIN Tab. Ziska Hyoscine butylbromide 10mg/tablet. 100's pack: 150.00 MRP BUTALPEN Tab. Desh Hyoscine butylbromide 10mg/tablet.

COLICON Tab. Square Dicycloverine hydrochloride BP 10mg/tablet 100's pack: 200.00 MRP COLICON Inj. Square Dicycloverine hydrochloride BP 20mg/2ml ampoule: i.m injection. 10 amps pack: 60.00 MRP CYCLOPAN Tab. Incepta Dicycloverine hydrochloride BP 10mg/tablet 100's pack: 200.00 MRP CYCLOPAN Syp. Incepta Dicycloverine hydrochloride BP 10mg/5ml: syrup 50ml bot: 30.00 MRP CYCLOPAN Inj. Incepta Dicycloverine hydrochloride BP 20mg/2ml ampoule: i.m injection. 5 amps pack: 40.00 MRP CYCLOVIN Tab. Somatec Dicycloverine hydrochloride BP 10mg/tablet 100's pack: 200.00 MRP CYCLOVIN Syp. Somatec Dicycloverine hydrochloride BP 10mg/5ml: syrup

GASTRO-INTESTINAL DRUGS

QIMP - 14 (8)

HYSOMIDE Inj. OpsoninHyoscine-n-butylbromide 20mg/1ml amp: injection 5 amps pack: 37.50 MRP

HYSOPAN Tab. RephcoHyoscine-butylbromide 10mg/tablet. 100's pack: 180.00 MRP

HYSOPAN Inj. RephcoHyoscine-n-butylbromide 20mg/1ml amp: injection 10 amps pack: 77.70 MRP

LOPAN Tab. NavanaHyoscine butylbromide 10mg/tablet. 100's pack:180.00 MRP

RELAPAN Tab. ChemistHyoscine butylbromide 10mg/tablet. 100's pack:152.00 MRP

RESOPAN Tab. GeneralHyoscine butylbromide 10mg/tablet. 100's pack:165.00 MRP

SAPEN Tab. SAPLHyoscine butylbromide 10mg/tablet. 100's pack:180.00 MRP

SPA-20 Tab. CosmicHyoscine butylbromide 20mg/tablet. 50's pack: 175.00 MRP

SPASMIN Tab. Doctor'sHyoscine butylbromide 10mg/tablet. 100's pack: 154.00 MRP

available as 60mg film coated tablet. Mode of action: Alverine citrate acts directly on the smooth muscle in the gut, causing it to relax, this prevents the muscle spasms which occur in the gut in conditions such as irritable bowel syndrome and diverticular disease. Alverine citrate also relaxes the smooth muscle of the uterus. It is therefore also used to treat painful menstruation, which is caused by muscle spasms in the uterus (dysmenorrhea). Ind: 1. Irritable bowel syndrome; 2. Bowel movement disturbances caused by small sacs or pouches in the wall of the gut (diverticular disease); 3. Abdominal pain associated with menstrual periods (primary dysmenorrhea); 4. Relief of other conditions associated with spasm of involuntary muscle. C/I: Paralytic ileus or known hypersensitivity to any of the ingredients. S/E: Possible side effects may include nausea, headache, dizziness, itching, rash and allergic reactions. Precaution: No significant precaution to be exercised. Pregnancy & lactation: Although no teratogenic effects have been reported, use during pregnancy or lactation is not recommended as evidence of safety in preclinical studies is limited.

100's pack: 175.00 MRP

DROTA Tab. HallmarkDrotaverine hydrochloride 40mg/tablet. 100's pack: 175.00 MRP

DROVI N Ta b. ACIDrotaverine hydrochloride 40mg/tablet. 100's pack: 175.00 MRP D R O VI N I n j . AC I Drotaverine hydrochloride 40mg in 2m1 ampoule: injection 5 amps pack: 35.00 MRP

DUVEN Ta b. Rasa Drotaverinehydrochloride 40mg/tablet. 100's pack: 175.00 MRP

ESPA Tab. Square Drotaverinehydrochloride 40mg/tablet. 100's pack: 175.00 IP

E S PA In j . S qua re Drotaverine hydrochloride 40mg in 2ml ampoule: injection5 amps pack: 35.00 MRP

NO-SPA Tab. AmbeeDrotaverine hydrochloride 40mg/tablet. 200's pack: 362.00 MRP NO-SPA Inj. Ambee Drotaverine hydrochloride 40mg in 2m1 ampoule: injection 10 amps pack: 79.50 MRP ROVA Tab. Chemico Drotaverine hydrochloride 40mg/tablet. 100's pack: 175.00 MRP

SPANIL Tab. BeximcoHyoscine butylbromide 10mg/tablet. 100's pack: 180.00 MRP

Dosage & admin: Adult: 60-120mg 1-3 times daily. Child under 12 years: Not recommended. Drug inter: There are no interactions reportedwith this medicine.

SPAN Tab. OpsoninDrotaverine hydrochloride 40mg/tablet. 100's pack: 175.00 MRP

SPASMOSON Tab. JaysonHyoscine butylbromide 10mg/tablet. 100's pack: 162.00 MRP Hyoscine butylbromide 20mg/1ml amp:injection. 10's pack: 55.60 MRP

TAVERIN Tab. BeximcoDrotaverine hydrochloride 40mg/tablet. 100's pack: 175.00 IP

ALVE Tab. OrionAlverine citrate 60mg/tablet (f.c). 50's pack:200.00 MRP

SPASMOSON Inj. Jayson

ALVERIN Tab. Rangs PharmaAlverine citrate 60mg/tablet (f.c). 30's pack:150.00 MRP

MEBEVERINE

21,33

SPASMOZEN Tab. ZenithHyoscine butylbromide 10mg/tablet. 100's pack: 180.00 MRP Hyoscine butylbromide 10mg/tablet. 100's pack: 150.00 MRP

SPASVERIN Tab. BeaconAlverine citrate 60mg/tablet (f.c). 50's pack: 200.00 MRP

MEBEVERINE HCI: Tablet/syrup. Ind: Antispasmodic to relief pain ingastrointestinal spasm & diarrhoea of irritable bowel syndrome. Caution: Paralytic ileus; pregnancy and breastfeeding; avoid in porphyria.

TYPAN Tab. Proteety

DROTAVERINE

21,33

PROPANTHELINE

21,33

DROTAVERINE HCI: Tablet/Injection Ind: Gastro-intestinal, biliary and ureteric colic,g.i spasm, urogenital spasm; peptic ulcer; peripheral vascular spasm, threatend abortion, spastic dysmenorrhoea and acute parametritis. S/E: Flushing of face, perspiration, tachycardia, hyperapnoea, may be found rarely.

Dose: Adult and child over 10 years, 135mg (1 tablet or 15m1 of liquid prepn.) 3 times daily preferably half an hour before meals. EVARIN Tab. Delta Mebeverinehydrochloride 135mg/tablet. 50's pack: 300.00 MRP

PROPANTHELINE: Tablet. Ind: Peptic ulceration, spastic colon, acutepancreatitis, aid in radiological procedures. C/1: Glaucoma, pyloric stenosis, obstructive conditions of the gastrointestinal or urinary tracts. S/E: Mild peripheral anti-cholinergic side-effects. Cautions: Prostatic bypertrophy, lactation.

IRIBAN Tab. InceptaMebeverine hydrochloride 135mg/tablet. 50's pack: 300.00 MRP MANIL Ta b. Gaco Mebeverine hydrochloride 135mg/tablet. 50's pack: 303.43 MRP

Adult: 15mg. 3 times daily before meals and 2 at night. Child: up to 2mg/kg body-wt daily in divided doses. PROPANTHENE Tab. GacoPropantheline bromide 15mg/tablet. 100's pack: 127.85 MRP

Dose: Oral, 1-2 tabs. once, can be repeated 2-3 times daily if necessary. By injection, 1-2 amp. i.m or sC, which can be repeated 2-3 times daily if necessary. DOT Tab. AcmeDrotaverine hydrochloride 40mg/tablet. 100's pack: 175.00 MRP

MAVE Tab. OpsoninMebeverine hydrochloride 135mg/tablet. 50's pack: 300.00 MRP

DOT Inj. AcmeDrotaverine hydrochloride 40mg in 2ml ampoule: injection 10 amps pack: 50.00 MRP

MESPA Tab. AmbeeMebeverine hydrochloride 135mg/tablet. 50's pack: 300.00 MRP Mebeverine hydrochloride 135mg/tablet. 50's pack: 300.0() MRP Mebeverine hydrochloride 135mg/tablet.

Other AntispasmodicsALVERINE87

MEVERIN Tab. Drug Inter. ROSTIL Tab. Beximco

DOTARIN Inj. PopularDrotaverine hydrochloride 40mg in 2m1 ampoule: injection 5 amps pack: 35.00 IP Drotaverine hydrochloride 40mg/tablet.

ALVERINE CITRATE: Tablet.Alverine citrate is a smooth muscle relaxant. It is

DOVER Tab. Nipa

QIMP-14 (9)

GASTROINTESTINAL DRUGS

50's pack: 300.00 IP VERON Tab. SK+F Mebeverine hydrochloride 135mg/tablet. 50's pack: 304.00 MRP

ALGIN Tab. Renata Tiemonium methylsulfate 50mg/tablet (f.c) 50's pack: 200.00 MRP ALGI N Inj. Rena ta Tiemonium methylsulfate 5mg/2ml ampoule: injection 5 amps pack: 75.00 MRP EMONIUM Tab. Beximco Tiemonium methylsulfate 50mg/tablet 50's pack: 200.00 IP NORVIS Tab. Square Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP NORVIS Inj. Square Tiemonium methylsulfate 5mg/2ml ampoule: injection 10 amps pack: 150.00 MRP O NI U M Ta b . Ori o n Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP O NI UM I n j . O r i o n Tiemonium methylsulfate 5mg/2ml ampoule: injection 5 amps pack: 75.00 MRP PARILLEX Tab. Drug Inter. Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP PREVIP Tab. General Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP SPASALGIN Tab. Opsonin Tiemonium methylsulfate INN 50mg/tablet 30's pack: 120.00 MRP SPASALGIN Inj. Opsonin Tiemonium methylsulfate 5mg/2ml ampoule: injection 5 amps pack: 75.00 MRP TIMEM Tab. Silva Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP TIMOLAX Tab. SAPL Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP TIMOTHY Tab. SK+F Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP TIMOTHY Inj. SK+F Tiemonium methylsulfate 5mg/2ml ampoule: injection 5 amps pack: 75.00 MRP TIMOZIN Tab. Incepta Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP TIMOZIN Inj. Incepta Tiemonium methylsulfate 5mg/2ml ampoule: injection 5 amps pack: 50.00 MRP TINIUM Tab. Acme Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 MRP TINIUM I nj. Acme Tiemonium methylsulfate 5mg/2ml ampoule: injection 5 amps pack: 75.00 MRP TINO Ta b. Delta Tiemonium methylsulfate INN 50mg/tablet 30's pack: 120.00 MRP T YNI UM Ta b . ACI Tiemonium methylsulfate INN 50mg/tablet 50's pack: 200.00 IP

TYNIUM Inj. ACI Tiemonium methylsulfate 5mg/2ml ampoule: injection 5 amps pack: 75.00 IP VERALGIN Tab. Aristopharma Tiemonium methylsulfate 50mg/tablet 50's pack: 200.00 MRP VERALGIN Inj. Aristopharma Tiemonium methylsulfate 5mg/2ml ampoule: injection 2ml amp x 10's pack: 150.00 MRP VISCER Tab. Techno Drugs Tiemonium methylsulfate 50mg/tablet 50's pack: 175.00 MRP VISCER Inj. Techno Drugs Tiemonium methylsulfate 5mg/2ml ampoule: injection 2ml amp x 10's pack: 120.00 MRP VISCERALGINE Tab. Nuvista Tiemonium methylsulfate 50mg/tablet 50's pack: 345.00 MRP VISCERALGINE Inj. Nuvista Tiemonium methylsulfate 5mg/2ml ampoule: injection 5 amps pack: 100.00 MRP VISET Tab. Healthcare Tiemonium methylsulfate 50mg/tablet 50's pack: 250.00 MRP VISET Inj. Healthcare Tiemonium methylsulfate 5mg/2ml ampoule: injection 10 amps pack: 150.00 MRP VISPAZIN Tab. Globe Tiemonium methylsulfate 50mg/tablet 50's pack: 200.00 MRP

OXYPHENCYCLIMINE

21,62

RANICON Tab. Renata Oxyphencyclimine HCI 5mg/tablet. Ind: Peptic ulcer, functional bowel syndrome. C/1; S/E: See under Hyoscine butyl bromide. Dose: 1-2 tabs. 2-3 times daily before meals. 100's pack: 82.00 MRP

OXYPHENONIUM BROMIDE

21,33

OXYPHENONIUM BROMIDE: Tablet Ind; C/1; S/E: See under Hyoscine butyl bromide. Adult: 1-2 tabs. several times daily, if necessary. Child: over 6yrs, 1/2 to 1 tablet 1-3 times daily. ANIL Tab. Gaco Oxyphenonium bromide 5mg/tablet. 100's pack: 143.10 MRP ANTRENEX Tab. Opsonin Oxyphenonium bromide 5mg/tablet. 100's pack: 125.00 MRP ANTRENYL Tab. Novartis Oxyphenonium bromide 5mg/tablet. 100's pack: 300.00 MRP A-SPASM Tab. Acme Oxyphenonium bromide 5mg/tablet. 100's pack: 143.00 MRP ISONIL Tab. Amico Oxyphenonium bromide 5mg/tablet. 100's pack: 141.00 MRP

TIEMONIUM

21,40

3. ANTICHOLINERGIC & ANTI-PSYCHOTIC COMBINATION PRODUCTSThere is no definite product molecules in this group. This is an innovative group of combined preparations.

TIEMONIUM METHYLSULFATE: Tablet/ InjectionThis is an antispasmodic drug which reduces visceral smooth muscles spasm. Ind: Acute spasmodic pain in gastrointestial and biliary diseases, and in urology and gynaecological origin. C/I: Glaucoma; difficulty to urinate (disorders of prostate or bladder). S/E: See under atropine; risk of hypotension & tachycardia; occasional retention of urine in excessive or overdoses. Caution: See under atropine; avoid taking this drug without medical advice during pregnancy or breast feeding. Dosage & Admin: Adult- by mouth, the usual dosages is 2 to 6 tablets (100-300mg) daily in divided doses as required; by injection usual dosages is 5mg by slow i.m or i.v injection 3 times daily.

TRIFLUOPERAZINE + 65 ISOPROPAMIDETRIFLUOPERAZINE + ISOPROPAMIDE: Tablet Combination preparations of trifluoperazine and isopropamide are available in three fixed-dose presentations, viz: i. Trifluoperazine 1mg & isopropamide 5mg, ii. Trifluoperazine 2mg & isopropamide 5mg, & iii. Trifluoperazine 2mg & isopropamide 7.5mg. In these preparations, trifluoperazine is a piperazine phenothiazine derivative with antipsychotic & antiemetic properties; isopropamide is a long-acting synthetic anticholinergic agent. Mode of action: As isopropamide is a long-acting synthetic anticholinergic agent, it provides 12hour antisecretory-antispasmodic activity. Trifluoperazine as a piperazine phenothiazine derivative, it's mode of action has not been definitely established, but like other most phenothiazines, trifluoperazine possesses weak anticholinergic & possibly alpha-adrenergic

GASTRO-INTESTINAL DRUGS

QIMP-14 (10)

blocking activities. Ind: This combined product is indicated particularly where anxiety, tension, worry or other emotional factors are thought to be wholly or partially responsible for the digestive dysfunction. This product may be employed to advantage in the treatment of a wide range of gastrointestinal disorders, including such conditions as peptic ulcer, gastritis, hyperchlorhydria, functional diarrhoea, irritable or spastic colon, pyloroduodenal irritability, pylorospasm, acute nonspecific gastroenteritis, biliary dyskinesia and chronic cholelithiasis, duodenitis, gastrointestinal spasm; it may also be used to treat genitourinary spasm. In addition to the convenience of twicedaily dosage, this product can provide the following significant therapeutic advantages: continuous reduction of gastric secretion, continuous inhibition of spasm and motility, continuous relief of anxiety and tension, continuous control of nausea and vomiting. C/I: In comatose states and in the presence of glaucoma, cardiospasm, obstructive uropathy (e.g bladder neck obstruction due to prostatic hypertrophy) or obstructive lesions of the gastrointestinal tract (as in achalasia, obstructive or paralytic ileus, phyloroduodenal stenosis, etc), intestinal atony of the elderly or debilitated patient, severe ulcerative colitis, toxic megacolon complicating ulcerative colitis. Because of the antiemetic action of the trifluoperazine component, brand name should not be used where nausea and vomiting are believed to be evidence of intestinal obstruction or brain tumor. S/E: The usual anticholinergic side effects are dry mouth, blurred vision, urinary hesitancy and retention, and constipation. Skin rash may occur rarely. A few patients sensitive to phenothiazine compounds may experience a transient unpleasant agitation, or jitteriness, characterized by restlessness and sometimes by insomnia. These symptoms often disappear spontaneously. Where the effect is particularly bothersome, the concomitant administration of a mild sedative may be helpful. Phenothiazines, in some patients on long term therapy, can cause tardive dyskinesia which may last for months or years; the risk appears greater in elderly patients. Precautions: Use with caution in elderly patients, in patients with cardiac impairment, hyperthyroidism or hiatal hernia associated with reflux esophagitis. Pregnancy & lactation: Use during pregnancy should be restricted to those cases where the potential benefit to the mother outweighs the potential risk to the fetus. Adequate human data on use during lactation and adequate animal reproduction studies are not available. Dosage & admin: Adults: For the majority of patients, the usual dose recommendation is 1 tablet of trifluoperazine 2mg & isopropamide 5mg twice daily (every 12 hours). Low dose preparation (i.e 1 tablet of trifluoperazine 1mg & isopropamide 5mg) may be preferred where there is relatively little psychic distress. A higher dose (i.e 1 tablet of trifluoperazine 2mg & isopropmaide 7.5mg) is specially useful for those patients in whom a greater degree of antispasmodic and antisecretory action is desired.

TELABID 1 Tab. SK+F Trifluoperazine hydrochloride USP equivalent to trifluoperazine 1mg & isopropamide iodide USP equivalent to isopropamide 5mg/tablet (filmcoated) 50's pack: 100.00 MRP TELABID 2 Tab. SK+F Trifluoperazine hydrochloride USP equivalent to trifluoperazine 2mg & isopropamide iodide USP equivalent to isopropamide 5mg/tablet (filmcoated) 50's pack: 150.00 MRP TELABID Forte Tab. SK+F Trifluoperazine hydrochloride USP equivalent to trifluoperazine 2mg & isopropamide iodide USP equivalent to isopropamide 7.5mg/tablet (filmcoated) 30's pack: 150.00 MRP

developed blood-brain barrier. Dosage & Admin: Adults- acute nausea and vomiting (including drug induced), 10-20mg every 4-8 hours daily orally; maximum period of treatment is 12 weeks. Functional dyspepsia, 10-20mg 3 times daily orally before foods & at night; maximum period of treatment is 12 weeks. Children- nausea and vomiting following cytotoxic or radiotherapy only, 0.2-0.4mg/kg every 4-8 hours daily. Functional dyspepsianot recommended. Note: Domperidone oral preparations should be taken 15-30 minutes before a meal. Drug inter: Domperidone may reduce the hypoprolactinaemic effect of bromocriptine. The action of domperidone on g.i function may be antagonized by anti-muscarinics and opioid analgesics.

4. MOTILITY STIMULANTS/ DOPAMINE ANTAGONISTSDOMPERIDONE21,26

DOMPERIDONE:Tablet/Suspension/ Suppositories Introduction & mode of action: Domperidone is a dopamine antagonist. It acts peripherally rather than central action; since it can't readily enter the central nervous system due to bloodbrain barrier, its effects are confined to the periphery and acts principally at the receptor site in the chemoreceptor trigger zone. Ind: In adult- i. prevention and symptomatic relief of acute nausea and vomiting from any cause including cytotoxic therapy, radiotherapy and anti-parkinsonism therapy; ii. functional dyspepsia; not recommended for routine prophylaxis of post-operative vomiting or for chronic administration. In children- the use of domperidone is restricted to nausea and vomiting following cytotoxic or radiotherapy only; not recommended for other causes. C/I: Known case of hypersensitivity to this drug; neonates. Pregnancy & lactation: In pregnancy, the safety of domperidone has not been proven and hence it is not recommended during pregnancy. In lactating mother, domperidone may precipitate galactorrhoea & improve post natal lactation; it is also secreted in breast milk but in very small quantities insufficient to be considered harmful; but its use in lactating mother should be very cautiously observed. S/E: Domperidone may cause increased prolactin production (1.3%), which may result in galactorrhoea, gynaecomastia; soreness and reduced libido. Other side-effects may includedry mouth, nervousness, drowsiness, skin rash and itching. Extra-pyramidal reactions are also reported very rarely in some clinical studies. Cautions: Domperidone should be used with absolute caution in case of young children, because there may be an increased risk of extrapyramidal reactions, since drug may enter into the central nervous system due to an incompletely

ADEGUT Tab. Supreme Domperidone maleate 10mg/tablet 50's pack: 75.00 MRP ADEGUT Susp. Supreme Domperidone 5mg/5ml: suspension 60m1 bot: 28.00 MRP ADOREX Tab. Ambee Domperidone maleate 10mg/tablet 100's pack: 95.00 MRP ADOREX Susp. Ambee Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP 100ml bot: 38.00 MRP ADOREX Drop Ambee Domperidone 5mg/ml: drop 15ml drop: 20.00 MRP ANET Tab. Chemico Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP ANET Susp. Chemico Domperidone 5mg/5ml: suspension 60m1 bot: 28.00 MRP APEDOM Tab. Apollo Domperidone maleate 10mg/tablet 50's pack: 100.00 MRP APEDOM Susp. Apollo Domperidone 5mg/5ml: suspension 60ml bot: 27.00 MRP APULDON Tab. Aristopharma Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP APULDON Susp. Aristopharma Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP APULDON Drop Aristopharma Domperidone 5mg/ml: drop 15ml drop: 20.00 MRP ATIDON Tab. Asiatic Domperidone maleate 10mg/tablet 50's pack: 100.00 MRP ATIDON Susp. Asiatic

QIMP-14 (11)

GASTRO-INTESTINAL DRUGS

Domperidone 5mg/5ml: suspension 60ml bot: 25.00 MRP AVOMIT Tab. Chemist Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP AVOMIT Susp. Chemist Domperidone 5mg/5ml: suspension 60m1 bot: 28.00 MRP BPDON Tab. Bristol Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP COSY Tab. Orion Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP COSY Susp. Orion Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP 100ml hot: 38.00 MRP CPDOM Tab. Cosmo Pharma Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DEFLUX Tab. Beximco Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DEFLUX DT Tab. Beximco Domperidone maleate 20mg/dispersible tablet 50's pack: 100.00 MRP 60's pack: 120.00 MRP 100's pack: 200.00 MRP DEFLUX Susp. Beximco Domperidone 5mg/5ml: suspension 100ml bot: 38.00 MRP DEFLUX Drop Beximco Domperidone 5mg/ml: drop 15m1 drop: 20.00 MRP DEGUT Tab. Delta Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DEGUT Susp. Delta Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP DOMAR Tab. Pacific Domperidone maleate 10mg/tablet 100's pack: 190.00 MRP DOMAR Susp. Pacific Domperidone 5mg/5ml: suspension 60ml bot: 25.00 MRP 100ml bot: 40.00 MRP DOMEE-J Tab. Jalalabad Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DOMIDON Tab. Ziska Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DOMIDON Susp. Ziska Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP DOMILIN Tab. General Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DOMILIN Susp. General Domperidone 5mg/5ml: suspension 100m1 hot: 40.00 MRP DOMILUX Tab. Popular Domperidone maleate 10mg/tablet 100's pack: 100.00 IP DOMILUX Susp. Popular Domperidone 5mg/5ml: suspension 60m1 bot: 28.00 IP DOMIN Tab. Opsonin

Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DOMIN Susp. Opsonin Domperidone 5mg/5ml: suspension 60m1 bot: 28.00 MRP DOMIN Drop Opsonin Domperidone 5mg/ml: drop 15ml drop: 20.00 MRP DOMINAT Tab. Nipa Domperidone maleate 10mg/tablet 50's pack: 100.00 MRP DOMINAT Susp. Nipa Domperidone 5mg/5ml: suspension 60m1 bot: 27.00 MRP DOMINOL Tab. White Horse Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DOMPEN Tab. Millat Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP DOMPI Tab. Alco Pharma Domperidone maleate 10mg/tablet 100's pack: 150.00 MRP DOMPI Susp. Alco Pharma Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP DOMSIL Tab. Silva Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DOMSIL DT Tab. Silva Domperidone maleate 20mg/dispersible tablet 100's pack: 200.00 MRP DOMSIL Susp. Silva Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP 100m1 bot: 38.00 MRP DON-A Tab. Acme Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DON-A Susp. Acme Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP DON-A Paed. Susp. Acme Domperidone 1 mg/1ml: suspension 30ml bot: 20.00 MRP DON-A Suppo. Acme Domperidone 15mg & 30mg/ suppository. Ind: See above under the text. Use & admin: Adult: 30 to 60mg every 4 to 8 hours. Children: Maximum daily dose 30mg for the babies of 10-15kg body weight. Suppositories are to be inserted per rectum. During insertion patient should lie on his/her left with flexed right hip and knee. 15mg suppository x 10's pack: 50.00 MRP 30mg suppository x 10's pack: 80.00 MRP DOPADON Tab. Ibn Sina Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DOPADON Susp. Ibn Sina Domperidone 5mg/5ml: suspension 60m1 bot: 25.00 MRP DOPON Tab. SAPL Domperidone maleate 10mg/tablet 50's pack: 50.00 MRP DORIDON Tab. Medicon Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP DORIDON Drop Medicon

Domperidone 5mg/ml: drop 15m1 drop: 19.00 MRP DPDONE Tab. CPL Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP DPDONE Susp. CPL Domperidone 5mg/5ml: suspension 60m1 bot: 25.00 MRP DUDON Tab. Kumudini Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP DUDON Susp. Kumudini Domperidone 5mg/5ml: suspension 100ml bot: 26.00 MRP DYSNOV Tab. UniHealth Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP DYSNOV Susp. UniHealth Domperidone 5mg/5ml: suspension 100ml hot: 38.00 MRP DYSNOV Drop UniHealth Domperidone 5mg/ml: drop 15ml drop: 20.00 MRP EDONE Tab. Zenith Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP EDONE Susp. Zenith Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP 100ml bot: 38.00 MRP ELIDOM Tab. Elixir Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP EMEDON Tab. Cosmic Domperidone maleate 10mg/tablet 50's pack: 75.00 MRP EMIDOM Tab. Somatec Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP EMIDOM Susp. Somatec Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP EMIDOM Drop Somatec Domperidone 5mg/ml: drop 15ml drop: 20.00 MRP ERIDON Tab. Doctor's Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP ERIDON Susp. Doctor's Domperidone 5mg/5ml: suspension 60m1 bot: 25.00 MRP ESOGUT Tab. Biopharma Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP ESOGUT Susp. Biopharma Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP ESOGUT Drop Biopharma Domperidone 5mg/ml: drop 15ml drop: 20.00 MRP GIDORA Tab. Rephco Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP GIDORA Susp. Rephco Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP LORIDON Tab. Modern Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP LORIDON Susp. Modern

GASTRO-INTESTINAL DRUGS

QIMP-14 (12)

Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP Domperidone 5mg/ml: drop 15ml drop: 20.00 MRP

100's pack: 200.00 MRP

100's pack: 200.00 MRP

OMID Susp. DeshDomperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP

LORIDON Drop. Modern

SANDOM Susp. Sanofi AventisDomperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP

OMIDON Tab. InceptaDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP

SANDOM Drop Sanofi AventisDomperidone 5mg/ml: drop 15m1 drop: 20.00 MRP Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP Domperidone 5mg/5ml: suspension 60ml bot: 27.00 MRP Domperidone maleate 10mg/tablet 50's pack: 75.00 MRP

Domperidone maleate 10mg/tablet 100's pack: 200.00 IP Domperidone 5mg/5ml: suspension 60ml bot: 28.00 IP 100ml bot: 38.00 IP

LOVAL Tab. Jayson

OMIDON D Tab. InceptaDomperidone maleate 20mg/dispersible tablet 100's pack: 200.00 MRP

LOVAL Susp. Jayson

SKYDON Tab. Skylab SYDON Tab. Syntho

OMIDON Susp. InceptaDomperidone 5mg/5ml: suspension 60m1 bot: 28.00 MRP 100m1 bot: 38.00 MRP Domperidone maleate 10mg/tablet 100's pack: 100.00 MRP

MERIN Tab. EdrucDomperidone maleate 10mg/tablet 100's pack: 150.00 IP Domperidone 5mg/5ml: suspension 100ml bot: 38.00 IP

SYDON Susp. Syntho

PARIDON Tab. Drug Inter.

MERIN Susp. Edruc

TYDON Tab. Proteety

MOTIDOM Tab. MedimetDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP Domperidone maleate 10mg/tablet 100's pack: 200.00 MRP

PARIDON Susp. Drug Inter.Domperidone 5mg/5ml: suspension 100ml bot: 32.00 MRP

ULDOM Tab. Ultra PharmaDomperidone maleate 10mg/tablet 100's pack: 100.00 MRP

P-DON Tab. PharmadeshDomperidone maleate 10mg/tablet 100's pack: 100.00 MRP

MOTIFAST Tab. Square

UNIDONE Tab. GacoDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP

P-DON Susp. PharmadeshDomperidone 5mg/5ml: suspension 60m1 bot: 24.00 MRP

MOTIGEN Tab. Novo HealthcareDomperidone maleate 10mg/tablet 50's pack: 100.00 MRP

VAVE Tab. ACIDomperidone maleate 10mg/tablet (f.c). 150's pack: 300.00 MRP

PERI Tab. HudsonDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP

MOTIGUT Tab. SquareDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP

VAVE Susp. ACI

MOTIGUT Susp. SquareDomperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP

PERI Susp. HudsonDomperidone 5mg/5ml: suspension 100ml bot: 35.00 MRP

Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP 100ml bot: 38.00 MRP Domperidone 5mg/ml: drop 15ml drop: 20.00 MRP

PERION Tab. GlobeDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP

VAVE Drop ACI

MOTIGUT Drop SquareDomperidone 5mg/ml: drop 15ml drop: 20.00 MRP

PERION Susp. GlobeDomperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP 100ml bot: 38.00 MRP

XEPADON Tab. AmicoDomperidone maleate 10mg/tablet (f.c). 50's pack: 100.00 MRP Domperidone 5mg/5ml: suspension 60ml bot: 25.00 MRP

MOTIL Tab. Hallmark

Domperidone maleate 10mg/tablet 100's pack: 150.00 MRP

XEPADON Susp. Amico

MOTIL Susp. HallmarkDomperidone 5mg/5ml: suspension 100ml bot: 28.00 MRP

PREDON Tab. NavanaDomperidone maleate 10mg/tablet 80's pack: 160.00 IP

XEPADON Drop AmicoDomperidone 5mg/ml: drop 15ml drop: 18.00 MRP

MOTILANT Tab. MarksmanDomperidone maleate 10mg/tablet 100's pack: 100.00 MRP Domperidone 5mg/5ml: suspension 60ml bot: 27.00 MRP

PREDON Susp. NavanaDomperidone 5mg/5ml: suspension 60ml bot: 28.00 IP

MOTILANT Susp. Marksman MOTILEX Tab. Techno Drugs

PROTIX Tab. ApexDomperidone maleate 10mg/tablet 100's pack: 150.00 MRP

METOCLOPRAMIDE

21,23

PROTIX-DT Tab. ApexDomperidone maleate 10mg/dispersible tablet 50's pack: 100.00 MRP

METOCLOPRAMIDE HCI: Tablet/ syrup/ drop/injectionIt is an effective anti-emetic drug. It has got a central anti-emetic effect & a peripheral action on the gut as dopamine antagonist, as a result it enhances motility of the upper gastrointestinal tract & thus hastens gastric emptying. Ind: Non ulcer dyspepsia, for speeding the transit of barium during intestinal follow through examination, reflux oesophagitis and also in non specific or cytotoxic nausia and vomiting. S/E: Extrapyramidal reaction's, drowsiness, constipation, gynaecomastia, galactorrhoea. Cautions: Renal impairment, immediately after abdominal surgery, Parkinsonism & children.

Domperidone maleate 10mg/tablet 50's pack: 75.00 MRP

MOTILEX Susp. Techno DrugsDomperidone 5mg/5ml: suspension 60ml hot: 25.00 MRP Domperidone maleate 10mg/tablet 50's pack: 100.00 MRP

PROTIX Susp. ApexDomperidone 5mg/5ml: suspension 100ml bot: 25.00 MRP

MOTIPER Tab. Mystic

PROTIX Drop ApexDomperidone 5mg/ml: drop 15ml drop: 20.00 MRP

MOTIPER Susp. MysticDomperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP

REMADON Tab. RemanDomperidone maleate 10mg/tablet 100's pack: 195.00 MRP

MYODON Tab. PeoplesDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP

RIDON Tab. SK+FDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP Domperidone 5mg/5ml: suspension 60ml bot: 28.00 MRP 100m1 bot: 38.00 MRP

RIDON Susp. SK+F

MYODON Susp. PeoplesDomperidone 5mg/5ml: suspension 60ml bot: 25.00 MRP

Adult: 15 to 20 years 5-10mg; others, 10mg. Both 3 times daily. Child: Under 1 yr, 1 mg twice daily; 1-3 yrs. 1mg 2 or 3 times daily; 3-5 yrs. 2mg 2 or 3 times daily; 5-14 yrs. 2.5-5mg 3 times daily. All orally, i.m or i.v. Usual max. doses, all ages 0.5mg/kg body-wt. daily. Preparations: See under anti-vomiting drugs inthe chapter of CNS products.

NOBURN Tab. BeaconDomperidone maleate 10mg/tablet 100's pack: 200.00 MRP Domperidone maleate 10mg/tablet

RIDON Drop SK+FDomperidone 5mg/ml: drop 15ml drop: 20.00 MRP

OMID Tab. Desh

SANDOM Tab. Sanofi Aventis

Domperidone maleate 10mg/tablet

QIMP-14 (13)

GASTROINTESTINAL DRUGS

5. ULCER HEALING DRUGS4.1 H2 -receptor antagonists Selective antimuscarinics Chelates and complexes Prostaglandin analogues Proton pump inhibitors Therapy for H. Pylori eradication 4.7 Other ulcer-healing drugs 4.2 4.3 4.4 4.5 4.6

20mg x 50's pack: 76.20 MRP 40mg x 50's pack: 151.71 MRP

FAMODIN Tab. AcmeFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 150.00 MRP 40mg x 100's pack: 300.00 MRP

FAMOJ Tab. JalalabadFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 190.00 MRP 40mg x 50's pack: 190.00 MRP

Anaphylactoid reactions & skin rashes have been reported rarely. Caution: Caution should be taken in case of renal impairment, pregnancy, lactation; exclude malignant diseases before treatment. Carry out periodic axamina tions of patients on prolonged therapy.

H2 -receptor antagonistsCIMETIDINE21, 33

FAMOTAB Tab. PharmadeshFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 175.00 MRP 40mg x 50's pack: 175.00 MRP

Dosage & admin: By mouth: Adult, Benign gastric and duodenal ulcer- 150mg (1 tab or 2 tsf) b.i.d in the morning and at bed time; or 300mg at bed time for 4 weeks; maintenance therapy, 150mg at bed time. Reflux oesophagitis- 150mg b.i.d for upto 8 weeks. Zollinger-Ellison syndrome- the starting dose is 150mg t.d.s and may be increased as necessary to 900mg (six tablets). Child- Under 8 yrs. not recommended; over 8 yrs. upto 150mg twice daily. Parenteral administration: By injection, adult50mg i.m or by slow i.v injection or infusion, repeated 6 to 8 hourly. Child- not recommended. By i.v infusion, 25mg (or 50ml)/hour for 2 hours; may be repeated every 6-8 hours. Prophylaxis of stress ulceration, initially slow i.v infusion of 50mg (as above) then continuous infusion of 125-250mcg/kg per hour. In patients with severely impaired renal function having a creatinine clearance less than 50ml/min, the recommended dosage is 50mg every 18-24 hours. If the patient's condition requires, the frequency of dosing may be increased to every 12 hours or even further with caution. Child- not recommended.

FAMOTACK Tab. SquareFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 150.00 MRP 40mg x 50's pack: 150.00 MRP

CIMETIDINE: Tablet/Syrup/Injection. Ind: Peptic ulceration, recurrent and stomalulceration, Zollinger-Ellison syndrome; Reflux oesophagitis and other conditions where a reductation of gastric acid is beneficial, erosive gastritis with bleeding. Cautions: Impaired renal functions (reduce dosage), exclude malignant disease, as cimetidine may mask symptoms and delay treatment; long term treatment should be avoided (if possible) otherwise the patient should be kept under observation or monitored; avoid abrupt withdrawal of treatment, concurrent admin. of anticoagulants or phenytoin. S/E: Occasional diarrhoea, dizziness, rashes, rarely mental confusion and gynaecomastia.

FAMOTID Tab. Drug InterFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 200.00 MRP 40mg x 100's pack: 400.00 MRP

FAMOTIN Tab. Doctor'sFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 142.00 MRP 40mg x 100's pack: 380.00 MRP

NACID Tab. SonearFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 200.00 MRP 40mg x 50's pack: 190.00 MRP

NOTAC Tab. CPLFamotidine 40mg/tablet 40mg x 100's pack: 300.00 MRP

Dose: Adult- by mouth, duodenal & benign gastric ulcer, 400mg, 2 times daily with breakfast & at bed time or 800 mg at bedtime for minimun 4 weeks, then 400mg. once or twice daily as maintenance dose. Reflux oesophagitis- 400mg 4 times a day after meals. By injection: 200mg i.m or slow i.v (100-150mg /hour) 4 to 6 hourly, max. dose 2 gm. daily. Child: Not recommended. G-CIMETIDINE Inj. GonoshasthayaCimetidine 200mg/2ml ampoule: injection 25 amps pack: 107.25 MRP

NOVATAC Tab. ACIFamotidine 20mg & 40mg/tablet. 20mg x 100's pack: 225.00 MRP 40mg x 100's pack: 410.00 MRP

PEPTID Tab. OpsoninFamotidine 20mg & 40mg/tablet. 20mg x 100's pack: 190.00 MRP 40mg x 100's pack: 380.00 MRP

SERVIPEP Tab. NovartisFamotidine 20mg & 40mg/tablet 20mg x 50's pack: 133.50 IP 40mg x 50's pack: 253.00 IP

FAMOTIDINE

21,33

YAMADIN Tab. BeximcoFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 190.00 IP 40mg x 100's pack: 380.00 IP

ACEPTIN-R Tab. AsiaticRanitidine 150mg/tablet 100's pack: 200.00 MRP

FAMOTIDINE: Tablet Ind: Benign gastric & duodenal ulcer, refluxoesophagitis, Zollinger- Ellison syndrome. S/E: See under cimetidine Cautions: see under cimetidine; does not inhibit hepatic miceosomal drug metabolism.

ZACTROL Tab. PeoplesFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 155.00 MRP 40mg x 100's pack: 300.00 MRP

ACIN Tab. Bio-pharmaRanitidine 150mg & 300mg/tablet 150mg x 100's pack: 200.00 MRP 300mg x 50's pack: 175.00 MRP

Dose: Benign gastric and duodenal ulceration, treatment, 40mg at night for 4-8 weeks; maintenance, 20mg at night. Reflux oesophagitis, 20-40mg twice daily for 612 weeks. Zollinger-Ellison syndrome, 20mg every 6 hours (higher dose in those who have previously been receiving another H2antagonist). AXIDIN Tab. UniHealthFamotidine 20mg & 40mg/tablet 20mg x 100's pack: 150.00 MRP 40mg x 100's pack: 300.00 MRP Famotidine 20mg & 40mg/tablet

RANITIDINE

21,33

ALIN Tab. RephcoRanitidine 150mg/tablet 100's pack: 200.00 MRP

RANITIDINE: Tablet/Syrup/Injection Ind: Duodenal, benign gastric and postoperativeulceration, reflux oesophagitis, Zollinger- Ellison syndrome and other conditions where a reduction of gastric acid is beneficial. Parenteral administration (injection/infusion) is specially indicated for the treatment of hospitalized patients with pathological hypersecretory conditions, intractable duodenal ulcers, and to prevent acid aspiration in obstetric patients at delivery. S/E: No serious adverse effects have been reported to date. But rare and transient nausea, headache, dizziness and diarrhoea may occur.

ANTAC Tab. AmbeeRanitidine 150mg/tablet 100's pack: 180.00 MRP

ANTAC Syp. AmbeeRanitidine 75mg/5ml: syrup 100m1 bot: 40.00 MRP

ANTAC I nj. Ambee Ranitidine50mg/2ml ampoule: injection 10 amps pack: 53.00 MRP

ASINAR Tab. Sanofi AventisRanitidine 150mg/tablet 150mg x 100's pack: 200.00 MRP

FAMO Tab. Gaco

BENTID-150 Tab. Benham

GASTRO-INTESTINAL DRUGS

QIMP-14 (14)

Ranitidine 150mg/tablet 100's pack: 200.00 IP

MUTAC-150 Tab. SaltonRanitidine 150mg/tablet 150mg x 100's pack: 200.00 MRP

dose. It contains no preservatives. 100m1 bot: 35.00 MRP

DENITINE Tab. DoctorsRanitidine 150mg/tablet 100's pack: 150.00 MRP

PROTEC-R Tab. GlobexRanitidine 150mg/tablet 100's pack: 100.00 MRP

MYSTIN-R Tab. MysticRanitidine 150mg/tablet. 100's pack: 200.00 MRP

DETAC-150 Tab. Desh PharmaRanitidine 150mg/tablet 100's pack: 150.00 MRP

NEOCEPTIN-R Tab. BeximcoRanitidine 150mg & 300mg/tablet 150mg x 150's pack: 330.00 IP 300mg x 100's pack: 400.00 IP

RANBEX Tab. Novo HealthcareRanitidine 150mg/tablet 100's pack: 200.00 MRP

DUGAL Tab. RemanRanitidine 150mg & 300mg/tablet 150mg x 100's pack: 114.00 MRP 300mg x 50's pack: 200.00 MRP

RANI Tab. Cosmo PharmaRanitidine 150mg/tablet 100's pack: 202.00 MRP

NEOCEPTIN-R Syp. BeximcoRanitidine 75mg/5ml: syrup 100m1 bot: 45.00 IP

DURAN Tab. Techno DrugsRanitidine 150mg & 300mg/tablet 150mg x 100's pack: 200.00 MRP 300mg x 100's pack: 400.00 MRP

RANI-150 Tab. Alco PharmaRanitidine 150mg/tablet 100's pack: 200.00 MRP

NEOCEPTIN-R I.V Inf. BeximcoRanitidine hydrochloride 50mg in 100ml (0.5mg/ml ) bottle: i.v infusion 100ml bot: 101.00 IP

RANID 150 Tab. ZiskaRanitidine 150mg/tablet 100's pack: 110.00 MRP

DURAN Syp. Techno DrugsRanitidine 75mg/5ml: syrup 100m1 bot: 40.00 MRP

NEODIN-R Tab. SkylabRanitidine 150mg/tablet 100's pack: 205.00 MRP

RANIDIL Tab. MillatRanitidine 150mg/tablet 100's pack: 200.00 MRP

DURAN I.V Inf. Techno DrugsRanitidine hydrochloride 50mg in 100ml (0.5mg/ml ) bottle: i.v infusion 100m1 bot: 60.00 MRP

NEOPEP Tab. CPLRanitidine 150mg/tablet 150mg x 100's pack: 150.00 MRP Ranitidine 150mg/tablet 150mg x 100's pack: 150.00 MRP

RANIDIN Tab. AcmeRanitidine 150mg & 300mg/tablet 150mg x 100's pack: 200.00 MRP 300mg x 100's pack: 400.00 MRP RANIDIN Inj. Acme Ranitidine 50mg/2ml ampoule: injection 10 amps pack: 60.00 MRP

EDITIN-R Tab. EdrucRanitidine 150mg/tablet 100's pack: 223.00 IP

NEOSETIN R-150 Tab. Bristol NEOTACK Tab. Square

E DI T I N- R I n j . E d r u cRanitidine 50mg/2ml ampoule: injection 5 amps pack: 30.00 IP

Ranitidine 150mg & 300mg/tablet 150mg x 150's pack: 300.00 MRP 300mg x 100's pack: 400.00 MRP

RANILOC Tab. KumudiniRanitidine 150mg/tablet 100's pack: 150.00 MRP

E-TACK Tab. ElixirRanitidine 150mg/tablet 100's pack: 200.00 MRP

NEOTACK Syp. SquareRanitidine 75mg/5ml: syrup 100ml bot: 45.00 MRP

RANISON Tab. JaysonRanitidine 150mg/tablet 100's pack: 171.00 IP

EUCON Tab. PacificRanitidine 150mg/tablet 100's pack: 190.00 MRP

NEOTACK Inj. SquareRanitidine 50mg/2ml ampoule: injection 10 amps pack: 60.00 MRP

EXAC Tab. HallmarkRanitidine 150mg/tablet 100's pack: 150.00 MRP

RANISON Inj. Jayson Ranitidine 50mg/2ml ampoule: injection 10 amps pack: 62.80 IP RANISYN Tab. SynthoRanitidine 150mg/tablet 100's pack: 210.00 MRP

NEOTID Tab. ModernRanitidine 150mg/tablet 100's pack: 200.00 MRP

GASTROLOC Tab. BeaconRanitidine 150mg/tablet. 100's pack: 100.00 MRP

NEOTIN Tab. NipaRanitidine 150mg/tablet 100's pack: 200.00 MRP

RANIT Tab. PharmadeshRanitidine 150mg & 300mg/tablet. 150mg x 100's pack: 120.00 MRP 300mg x 50's pack: 150.00 MRP

GEPIN Tab. GeneralRanitidine 150mg/tablet 100's pack: 200.00 MRP

NORMACID Tab. ChemicoRanitidine 150mg/tablet 100's pack: 200.00 MRP

GEPIN Syp. GeneralRanitidine 75mg/5ml: syrup 100ml bot: 40.00 MRP 200m1 bot: 70.00 MRP

RANITAB Tab. SonearRanitidine 150mg/tablet 100's pack: 200.00 MRP

NORMA-H Tab. RenataRanitidine 150mg/tablet 150mg x 100's pack: 218.00 MRP

RANITEC-150 Tab. A.P.0 PharmaRanitidine 150mg/tablet 100's pack: 200.00 MRP

G-RANITIDINE Tab. GonoshasRanitidine 150mg/tablet. 100's pack: 142.00 MRP

ORTAC Tab. OrionRanitidine 150mg/tablet 100's pack: 200.00 MRP

RANITID Tab. OpsoninRanitidine 150mg/tablet 150mg x 150's pack: 300.00 MRP

H2-150 Tab. ApolloRanitidine 150mg/tablet. 100's pack: 200.00 IP

ORTAC I.V Inf. OrionRanitidine hydrochloride 50mg in 100ml (0.5mg/ml ) bottle: i.v infusion 100ml bot: 60.00 MRP

RANITID Inj. OpsoninRanitidine 50mg/2ml ampoule: injection 5 amps pack: 30.00 MRP

HI-TAC Tab. HudsonRanitidine 150mg/tablet. 100's pack: 150.00 MRP

PEOTID Tab. PeoplesRanitidine 150mg/tablet 100's pack: 210.00 MRP

RANITOR Tab. PopularRanitidine 150mg/tablet. 100's pack: 100.00 IP

INSEAC Tab. Ibn SinaRanitidine 150mg & 300mg/tablet 150mg x 100's pack: 200.00 IP 300mg x 48's pack: 184.32 IP

PEPTIDIN-150 Tab. CosmicRanitidine 150mg/tablet 100's pack: 150.00 MRP

RANIX Tab. ChemistRanitidine 150mg/tablet. 100's pack:75.00 MRP

JOVRAN Tab. BelsenRanitidine 150mg/tablet. 100's pack: 200.00 MRP

PEPTIL-H Tab. SK+FRanitidine 150mg/tablet 150mg x 100's pack: 200.00 MRP

RANI X Inj. Chemi s tRanitidine 50mg/1ml ampoule: injection 10 amps pack: 50.00 MRP

LIBRET I.V Inf. LibraRanitidine hydrochloride 50mg ir1 100ml (0.5mg/ml ) bottle: i.v infusion 100m1 bot: 55.00 MRP

PEPTONIL Tab. DecentRanitidine 150mg/tablet 100's pack: 200.00 MRP Ranitidine hydrochloride 50mg in 100m1 (0.5mg/ml ) bottle, premixed in 0.45% sodium chloride solution, for i.v administration as a single

RANTEC Tab. Medimet.Ranitidine 150mg & 300mg/tablet 150mg x 100's pack: 200.00 MRP 300mg x 50's pack: 175.00 MRP

LUMERAN Tab. AristopharmaRanitidine 150mg/tablet 150mg x 100's pack: 215.00 IP

PEPTOSOL I.V Inf. Opsosaline

RANTIN Tab. SeemaRanitidine 150mg/tablet 100's pack: 210.00 MRP

QIMP-14 (15)

GASTRO-INTESTINAL DRUGS

RANUL Tab. ApexRanitidine 150mg/tablet 100's pack: 150.00 MRP

150mg x 100's pack: 200.00 MRP

ZANTAC Tab. GlaxoSmithKlineRanitidine 150mg/tablet. 150mg x 100's pack: 404.00 MRP

REETAC-R Tab. NavanaRanitidine 150mg & 300mg/tablet. 150mg x 100's pack: 200.00 MRP 300mg x 50's pack: 200.00 MRP

ZENIDINE Tab. ZenithRanitidine 150mg/tablet. 100's pack: 150.00 MRP

RENICON Tab. MediconRanitidine 150mg/tablet. 100's pack: 185.00 MRP

ZENIL Tab. RangsRanitidine 150mg/tablet. 100's pack: 200.00 MRP

RHINE Tab. HealthcareRanitidine 150mg/tablet. 60's pack: 150.00 IP

ZODIN Tab. SomatecRanitidine 150mg/tablet. 100's pack: 200.00 MRP

ROSTID Tab. RasaRanitidine 150mg/tablet. 100's pack: 200.00 MRP

ZODIN Syp. SomatecRanitidine 75mg/5ml: syrup 100m1 bot: 40.00 MRP

RT 150 Tab. SilvaRanitidine 150mg/tablet. 100's pack: 200.00 MRP

ZOREP Tab. AmicoRanitidine 150mg & 300mg/tablet. 150mg x 100's pack: 150.00 MRP

SADIN Tab. SAPLRanitidine 150mg/tablet. 100's pack: 150.00 MRP

ZOSTAC 150 Tab. MarksmanRanitidine 150mg/tablet. 100's pack: 200.00 MRP

SUTAC Tab. SupremeRanitidine 150mg/tablet. 100's pack: 200.00 MRP

Prostaglandin analoguesMISOPROSTOL26

must use an effective contraceptive method while taking misoprostol. Incase of induction of labor: The pregnancy should have completed 38 weeks of gestation by reliable dating, or completed 36 weeks gestation with a maternal or fetal medical indication for induction of labor. Induction of labor is contraindicated in acute fetal distress, abruptio placenta, placenta previa or unexplained vaginal bleeding. The fetus should be in vertex presentation. Pregnancy & lactation: Misoprostol is contraindicated in pregnant women