PURE Sweden

A pilot study – first 158 men and women

Sweden: 9 milj. inhabitants

20 persons/km2

Göteborg: second largest city (500.000)

Sahlgrenska University

Hospital/Östra

Göteborg

Sweden

Population studies

since 1963 –

Data on ca 20,000

men and women

Birth years:

1913 to 1978

PURE – Swedish collaborative effort

Urban: Sahlgrenska University Hospital, Göteborg• Respiratory medicine – Prof Kjell Torén Dept of

Work & Environmental Medicine• Nutrition – Prof Lauren Lissner, Dept of

Epidemiology and Community Medicine• Cardiology – Prof Annika Rosengren, Dept of

Cardiovascular and Emergency MedicineRural: Skövde• Rural populations – Dr Ulf Lindblad, dr Kristina

Bengtsson, Dept of Family Medicine, Skövde

PURE Study

Görel

Anne

PURE – Sweden pilot

Feb-May 2005 Preparation, training

April 2005 Ethics approval

May-June 2005 2 grants submitted

Aug 2005 Start of recruitment

Sept-dec 2005 156 subjects investigated

Nov 2005 2 grants approved, partial funding

PURE – Sweden pilot

* 164 visits scheduled for January/February

URBAN RURAL

Total number of households surveyed (Contacted)

324 -

No of households with elgible subjects for the PURE Study

324 -

Total number of subjects eligible for the PURE study

N/A -

Total number of households responded

240

Total number of subjects for whom questionnaires were administered

158* -

Total number of subjects for whom measurements were made

158 -

Total number of subjects for whom blood samples were collected

158 -

Approach

• MONICA population, still living in Göteborg

• Subjects aged 25 to 44 in 1985, 1990 or 1995 + household members

• Random population sample + household members.

• Company/neighborhood approach: not feasible.

Plans for 2006

• Investigation of 1200 Göteborg subjects

• Pilot for rural population

• Submission of grant for regional support for 2007.

• Random population sample of defined rural communities.