Pulmonary Vascular Research Institute
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Transcript of Pulmonary Vascular Research Institute
Pulmonary Hypertension In Developing World
An Overview
Schistosomiasis10-20 M
High altitude5-7 M
Others
HIV
PHT in the Developing
World15-30 MPHT
in the developed world
0.5- 1 M
Pulmonary Hypertension in the world
Pulmonary Hypertension Associated with:
• Schistosomiasis • HIV • Congenital Heart Disease • Rheumatic valvular diseases • Chagas disease• Endomyocardial Fibrosis• High Altitude• Haemolytic anemia
Severe PHT due to Schistosomiasis
Courtesy of Dr. Ângela Pontes Bandeira
High altitude associated pulmonary hypertension
• More than 140 million people worldwide live >2500 m above sea level. – 80 M in Asia,– 35 M Andean mountains
• Genetic predisposition
• Other environmental factors
HIV associated pulmonary hypertension
• The prevalence is 0.5%• In Africa suggested that the prevalence
may range from 0.6% to 5%, – with higher numbers in the hospitalized as
opposed to ambulant patients
• The incidence however has not been affected by the introduction of the HAART treatment
Cardiac conditions associated pulmonary hypertension
• Cardiac pathology in the developing world may differ– Congenital heart diseases treated late– Pattern of the pathology may differ– Rheumatic fever and Rh.H.D.– Endomyocardial fibrosis– Chagas diseases
PVRI in Latin AmericaPVRI in Latin America
PVRI in China