Proprietary Information of AMA Aurora DSR ELOS TM Technology and key features AMA.
-
Upload
julie-thompson -
Category
Documents
-
view
216 -
download
0
Transcript of Proprietary Information of AMA Aurora DSR ELOS TM Technology and key features AMA.
Proprietary Information of AMA
ELOSTM Technology for Aesthetic medicine
•Utilize optical energy and electrical (radio frequency) simultaneously
•Two different selectivity mechanism for optimal treatment
•Epidermal cooling
•Active dermal monitoring TM
Proprietary Information of AMA
Aurora applications
• Aurora DS indicated for non invasive hair removal– Light hair– Dark skin types
• Aurora SR indicated for Skin Renewal– Pigmented lesion– Vascular lesion– Skin texture improvement
Proprietary Information of AMA
Existing technology for selective photothermolysis
• Optical energy: penetrating into the skin and selectively absorbed by the target– Lasers - monochromatic light – IPL produces broad spectrum of light
• Electrolysis basing on delivery of RF energy to the hair root by insertion of needle to each follicle (Thermolysis)
• ThermaCool By Thermage (RF) –unipolar system for wrinkle treatment
Proprietary Information of AMA
Light-based Hair removal
• Hair chromophore melanin - the same as of epidermis
• Dark epidermis has higher risk of damage
• Treatment of light hair is not effective
• Does not effect hair follicle and buldge directly
• Indeterminacy of light effect because of its scattering and reflection
• Strong absorption by dark hair shaft
• Penetration depth of a few millimeters
• High selectivity between hair shaft and dermis
• High efficiency for dark hair and light skin
_ +
Proprietary Information of AMA
What is the main Light problem ?
En
erg
y
Epidermis damage
Hairdamage
Dermis damage
Light Skin Dark Hair
Dark Skin Dark Hair
Light Skin Light Hair
Dark Skin Light Hair
Proprietary Information of AMA
Treatment window for light based systems
Light skin Dark hair
Dark skin Dark hair
Light skin Light hair
Dark skin Light hair
Efficacy energy level
LowLowHighHigh
Adverse effect energy level
HighLowHighLow
Treatment window
WideNarrowNarrowNot exist!
Over allGoodPoor results/ High risk
Poor results/ High risk
Can’t do!
Proprietary Information of AMA
Syneron ELOS Technology
• Two types of energies sources with
different selectivity mechanism • Optical energy: absorbed in the target
by the right choice of wavelength and pulse duration
• Electrical RF energy: Chromophore independent not sensitive to skin or target color!
Proprietary Information of AMA
Syneron ELOS Technology
• Reduce the optical energy to a safe level for all skin types
• Compensate for the lack of optical energy with electrical RF energy that is not sensitive to skin or target color
Proprietary Information of AMA
Temperature distribution created by light
• Light heats selectively hair shaft
• Bulge and follicle are damaged due to heat transfer from hair shaft
ShaftFollicle
Proprietary Information of AMA
RF energy properties
• Well known in medicine• Does not effect the melanin• All RF parameters (Voltage, Current,
Impedance) can be measured and controlled with high time resolution
• Skin impedance depends on temperature and can be used for skin heating monitoring where impedance drop is about 2% per C
Proprietary Information of AMA
Mechanism of RF selectivity I – Geometry Effect
Electrodes
• Current density is twice higher in the follicle than in surrounding tissue
• Heat generation is proportional to square of current density
Proprietary Information of AMA
Heat created by RF
• RF creates heat in the 30microns layer around the hair shaft
• Heated layer includes hair follicle and buldge
Proprietary Information of AMA
Mechanism of RF selectivity II – Impedance Decreases with Temperature
• Impedance linearly decreases with Temperature Increase
• RF current will flow at lower impedance part of the tissue and selectively heats it
• Light acts as a trigger – preheat the target for the RF current
Proprietary Information of AMA
Skin and follicle heating by RF
• Heat generationH=j2, where -conductivity, j-current density • Ratio between skin and follicle heating
Hfollicle=4 Hskin
• Skin temperature increase
Tskin=ERF /(S d Cskin)S-spot size, d-penetration depth, C-specific
heat
Tskin=16 /(2x0.4x4)=5°C• Follicle temperature increase
Tfollicle=4 Tskin=4x5=20°C
Proprietary Information of AMA
Heat created by combination of Light and RF
• Combination of two types of energy create uniform heating the shaft and follicle
Proprietary Information of AMA
Contribution of Light and RF in Heat generation
• Light provides high selectivity between hair shaft and dermis
• RF energy heats mostly hair follicle and does not react to melanin of epidermis
RFLight
Proprietary Information of AMA
RF Current Distribution
Cold epidermisCold epidermis
DermisDermis
Pre-heated vesselPre-heated vessel
Proprietary Information of AMA
Aurora pulse sequence
RF energy
Light
Testing pre-pulse to ensure
coupling and skin calibration for RF
monitoring
Intense pulse
Fine heat adjustment
RF energy
Proprietary Information of AMA
ISL safety feature
RF energyLight
Testing pre-pulse Intense pulse Fine heat adjustment
Impedance
Temperature
Energy
Proprietary Information of AMA
Light
Light
Impedance safety limit (ISL)
Light
RF energy
Light
ISL= 10%, energy is cut off
0
10
20
30
ISL= 30%, all energy is delivered
40
Proprietary Information of AMA
Treatment technique
• Incomplete contact cooling• All RF current is concentrated in
one point, potential for increased tissue temperature at contact points.
• Complete contact cooling• RF current is distributed over
entire electrode surface
Proprietary Information of AMA
Cross Section of Hair from scalp:
Hair Follicles after Aurora DS treatment
Proprietary Information of AMA
How Deep Does RF penetrate?
Human hair follicles at the edge of a treated area.
Depth is 3.5mm
Treated Normal
Proprietary Information of AMA
Light brown hair
Optical pulse at 20J/cm2 with no additional RF energy.
Optical pulse at 20J/cm2 and RF energy of 20J/cm3.
Proprietary Information of AMA
Treatment Case
Hair removal
RF: 18 J/cm3
Light: 25 J/cm2
Number of Sessions: 2
Pulse: Short
Pre-treatment Post-treatment
Follow-up: 6 months
Dr. J. Shaoul
Proprietary Information of AMA
Treatment Case
Hair removal
RF: 20 J/cm3
Light: 22 J/cm2
Number of Sessions: 2
Pulse: Short
Pre-treatment Post-treatment
Follow-up: 10 months
Dr. J. Shaoul
Proprietary Information of AMA
Treatment Case
Hair removal
RF: 18 J/cm3
Light: 26 J/cm2
Number of Sessions: 2
Pulse: Short
Pre-treatment
Post-treatment
Follow-up: 4 months
Dr. J. Shaoul
Proprietary Information of AMA
Hair Removal Study6 Month Follow-up
A. DelGiglio, J. Shaoul
0
10
20
30
40
50
60
70
80
90
Per
cen
tag
e A
vera
ge
Cle
aran
ce
3 Month 6 Month
Axilla
Bikini Line
Legs
Trunk
Face
Proprietary Information of AMA
Conclusion
• The Aurora DS device has a definite biological effect on hair including reddish blonde and gray hair
• Further studies in skin types 5 and 6, and on white hair, are on going
• With an observation period of ten months it is possible to say that this is the same degree of permanent hair loss that one sees with any other laser technology
Proprietary Information of AMA
Photo-rejuvenation Treatment Using ELOS Technology
• Pigmented Lesion• Vascular Lesion• Wrinkle and skin texture treatment
Proprietary Information of AMA
Treatment Case
Lentigo
RF: 20 J/cm3
Light: 15 J/cm2
Number of Sessions: 2
Pulse: Short
Pre-treatment
Post-treatment
Follow-up: 1month
Dr. J. Shaoul
Immediately
Proprietary Information of AMA
Treatment Case
Age spots
RF: 15 J/cm3
Light: 22 J/cm2
Number of Sessions: 1
Pulse: Short
Pre-treatment
Post-treatment
Follow-up: 1 month
Dr. C. Chess
Proprietary Information of AMA
Treatment Case
Rosacea
RF: 18 J/cm3
Light: 24 J/cm2
Number of Sessions: 3
Pulse: Short
Pre-treatment
Post-treatment
Follow-up: 1 month
Dr. S. Laughlin
Proprietary Information of AMA
Treatment Case
Rosaceaskin texture
RF: 20 J/cm3
Light: 15 J/cm2
Number of Sessions: 2
Pulse: Short
Pre-treatment Post-treatment
Follow-up: 1 month
Dr. J. Shaoul
Proprietary Information of AMA
Treatment Case
Skin renewal
RF: 20 J/cm3
Light: 26 J/cm2
Number of Sessions: 3
Pulse: Short
Pre-treatment
Post-treatment
Follow-up: 1 month
Dr. S. Laughlin
Proprietary Information of AMA
Treatment Case
Telangiectasia
RF: 20 J/cm3
Light: 23 J/cm2
Number of Sessions: 4
Pulse: Short
Pre-treatment
Post-treatmentFollow-up: 1 month
Dr. S. Laughlin
Proprietary Information of AMA
Treatment Case
Telangiectasia
RF: 15 J/cm3
Light: 22 J/cm2
Number of Sessions: 1
Pulse: Short
Pre-treatment Post-treatmentFollow-up: 1 month
Dr. C. Chess
Proprietary Information of AMA
Treated sites by clearance FDA Multi-Center Study
24%
20%
22%
28%
6%
0-20%
21-40%
41-60%
61-80%
81-100%
Proprietary Information of AMA
• Safety: use less optical energy – less epidermal damage•Deliver more selective energy to the treated target• Treat dark skin without compromising efficacy or safety• Treat light hairs • Additional safety features• Portable, multi-applications platform
Aurora major advantages