Principles of Infection Control and

Personal Protective Equipment

Learning Objectives• Learn principles of infection control:how to protect yourself and others

• Spot problems with infection control procedures

• Recognize ways to deal with such problems in different situations

• Learn to select and use appropriate personal protective equipment (PPE)

Session Overview

• Routes of disease transmission• Infection control methods and

personal protective equipment (PPE)

• Infection control precautions• How to put on and remove PPE

Remember…Your first obligation is to protect yourself!

If you have any doubt about your safety in any situation, avoid that situation!

GlossaryDecontamination (“decon”) - The removal

of harmful substances such as chemicals, harmful bacteria, or other organisms, from exposed individuals, rooms, and furnishings in buildings or in the outside environment.

Disease transmission - The process of the spread of a disease agent through a population

Glossary (cont’d)Infection control - Measures practiced by

health care personnel in health care facilities to prevent the spread of infectious agents

Personal protective equipment (PPE) - Specialized clothing or equipment worn by a worker for protect from a hazard

Routes of Disease Transmission

Chain of Infection

+Quantity ofpathogen

Virulence Route of transmission

Sensitivehost

Port

Routes of Transmission

• Respiratory– Cough– Sneeze

• Fecal-oral– Feces contaminate food, environment, or

hands

• Vector-borne– Transmitted by insects or other animals

Routes of TransmissionContact

Direct Contact• Host comes into

contact with reservoir

• Kissing, skin-to-skin contact, sexual intercourse

• Contact with animal, soil, or vegetation

Indirect Contact• Disease is carried from

reservoir to host

• Contaminated surfaces (fomites)

Examples:

Routes of TransmissionDroplet

Large droplets within ~1 meter (3 feet)

transmit infection via: – Coughing, sneezing, talking– Medical procedures

Examples:• Diphtheria• Pertussis (Whooping Cough)• Meningococcal meningitis

Routes of TransmissionAirborne (droplet nuclei)

Very small particles of evaporateddroplets or dust with infectious agentmay…

– Remain in air for a long time– Travel farther than droplets– Become aerosolized during procedures

Examples: • Tuberculosis• Measles (Rubeola)

Transmission of Influenza VirusesSeasonal

Influenza in Humans

Current Avian Influenza in Humans

Droplet most likely route

possible

Airborne possible at close distances

possible at close distances

Contact possible Most likely(bird to human), and possible (human to

human)

Video clip fromThe Great Fever

Infection Control Methodsand

Personal Protective Equipment(PPE)

Hand WashingMethod

• Wet hands with clean (not hot) water

• Apply soap• Rub hands together for about

20 seconds• Rinse with clean water• Dry with disposable towel or

air dry• Use towel to turn off faucet

Alcohol-based Hand Rubs• Effective if hands not visibly soiled• More costly than soap & water

Method• Apply appropriate (3ml) amount to

palms• Rub hands together, covering all

surfaces until dry

Personal Protective Equipment (PPE)

• When used properly can protect you from exposure to infectious agents

• Know what type of PPE is necessary for the duties you perform and use it correctly

Types of PPE

• Gloves• Gowns• Masks• Boots (for agricultural settings, not

used for human healthcare)• Eye protection

Types of PPEGloves

• Different kinds of gloves– Housekeeper gloves– Clean gloves – Sterile glove

• Work from clean to dirty

• Avoid “touch contamination”– Eyes, mouth, nose, surfaces

• Change gloves between patients

Types of PPEGowns or Coveralls• Fully cover torso• Have long sleeves• Fit snuggly at the wrist• Coveralls may have hood

and/or boots

Types of PPE

• Surgical masks– Cotton, paper– Protect against body fluids and large

particles

• Particulate respirators (N95)– Fit testing essential– Protect against small droplets and

other airborne particles

• Alternative materials (barrier)– Tissues, cloth

Masks and Respirators: Barriers and Filtration

Types of PPEParticulate Respirators• Three types: disposable, reusable, powered

air purifying respirators

• Disposable Particulate Respirators– Classified N95, N99, N100, R95, R99, R100, P95,

P99, P100– Letter indicates oil resistance: N = not resistant, R

= somewhat resistant, P = strongly resistant– Number is percent of airborne particles filtered

(e.g. N95 filters 95% of particles)

Types of PPE Boots (non-hospital settings) Eye Protection

– Face shields– Goggles

PPE Supplies• Maintain adequate, accessible supplies

• Creative alternatives (studies not done to asses effectiveness)– Mask: tissue, scarf– Gown: laboratory coat, scrubs

Working with Limited Resources

• Avoid reuse of disposable PPE items – Consider reuse of some disposable items

only as an urgent, temporary solution – Reuse only if no obvious soiling or

damage

• When prioritizing PPE purchase– Masks– Gloves – Eye protection

Infection Control Precautions

Precaution LevelsAll levels require hand hygiene

• Standard

Transmission based precautions:• Contact• Droplet • Airborne

Standard Precautions

• Prevent the transmission of common infectious agents

• Hand washing key

• Assume infectious agent could be present in the patient’s – Blood – Body fluids, secretions, excretions– Non-intact skin– Mucous membranes

PPE for Standard PrecautionsWear:• Gloves

• Gowns

• Eye Protection and / or Mask

If:• Touching

– Respiratory secretions– Contaminated items or surfaces– Blood & body fluids

• Soiling clothes with patient body fluids, secretions, or excretions

• Procedures are likely to generate splashes / sprays of blood, body fluids, secretions, excretions

Contact Precautions

Taken in addition to Standard Precautions

• Limit patient movement

• Isolate or cohort patients

• Gown + gloves for patient / room contact– Remove immediately after contact

• Do not touch eyes, nose, mouth with hands

• Avoid contaminating environmental surfaces

Contact Precautions

• Wash hands immediately after patient contact

• Use dedicated equipment if possible– If not, clean and disinfect between uses

• Clean, then disinfect patient room daily– Bed rails– Bedside tables– Lavatory surfaces– Blood pressure cuff, equipment surfaces

Cleaning and Disinfection for Contact Precautions

• Detergents – Remove dirt, soiling– Mechanical force essential– Flush with clean water

• Disinfectants– Kill viruses, bacteria– Decontaminate surfaces– Type depends on infectious agent– Use after detergent

Environmental Decontamination

• Cleaning MUST precede decontamination

• Disinfectant ineffective if organic matter is present

• Use mechanical force– Scrubbing– Brushing– Flush with water

Environmental Decontamination: Disinfecting

• Household bleach (diluted)

• Quaternary ammonia compounds

• Chlorine compounds (Chloramin B, Presept)

• Alcohol– Isopropyl 70% or ethyl

alcohol 60%

• Peroxygen compounds

• Phenolic disinfectants

• Germicides with a tuberculocidal claim on label

• Others

Using Bleach Solutions 1• First, clean organic material from

surfaces or items – wash with soap or detergent and water, rinse, dry.

• The CDC recommends using 5 tablespoons of liquid bleach per gallon of water.

• Leave nonporous surfaces (tile, metal, hard plastics, etc.) wet at least 10 minutes and allow to air dry.

Using Bleach Solutions 2• Leave porous surfaces (wood, rubber,

soft plastics, etc.) wet for 2 minutes. Rinse and air dry.

• Use household chlorine bleach (5.25 - 6% sodium hypochlorite); do not use scented or color safe bleaches.

• Use fresh diluted bleach daily!

• Wear gloves and eye protection!

Waste Disposal

• Use Standard Precautions– Gloves and hand washing– Gown + Eye protection

• Avoid aerosolization

• Prevent spills and leaks– Double bag if outside of bag is contaminated

• Incineration is usually the preferred method

Managing Linens and Laundry• Use Standard Precautions

– Gloves and hand hygiene– Gown – Mask

• Avoid aerosolization – do not shake

• Fold or roll heavily soiled laundry– Remove large amounts of solid waste first

• Place soiled laundry into bag in patient room

• Wash with normal detergent

Preventing Transmission in the Community

• Respiratory etiquette– Cover nose / mouth

when coughing or sneezing

• Hand washing!

Droplet Precautions• Prevent infection by

large droplets from– Sneezing– Coughing– Talking

• Examples– Neisseria meningitidis– Pertussis– Seasonal influenza

Droplet PrecautionsTaken in addition to Standard Precautions

• Place patients in single rooms or cohort 3 feet apart

• Wear surgical mask within 3 feet or 1 meter of patient

• Wear face shield or goggles within 3 feet or 1 meter of patient

• Limit patient movement within facility– Patient wears mask when outside of room

Airborne PrecautionsTaken in addition to Standard Precautions

• Prevent spread of infection through inhalable airborne particles

• Use for suspected or actual– Tuberculosis– Measles– Varicella– Variola– Avian Influenza

Airborne Precautions for Avian Influenza

• N95 respirator (or equivalent) for personnel– Check seal with each use

• Patient in isolation

• Airborne isolation room, if available– Air exhaust to outside or re-circulated with HEPA

filtration

• Patient to wear a surgical mask if outside of the isolation room

Negative Pressure Isolation Room

Natural Ventilation Cohorting Room

1 meter

Avian Influenza• Currently not easily transmitted human

to human• Routes of transmission to humans not

known, cannot rule-out any routes• Current transmission from poultry to

human or human to human for H5N1 requires very close contact

Interviewing - Asymptomatic Exposed Persons and Contacts

• Low-risk activity

• Routine use of PPE not recommended

• Maintain 3 feet distance between interviewer and interviewee

• Use proper hand hygiene– May use hand sanitizer (at least 60% alcohol) if

hands not visibly soiled

Interviewing - Symptomatic Exposed Persons

• Higher risk activity

• PPE recommended in community and healthcare facility– Contact precautions– Droplet precautions– N95 respirator

• In healthcare facility, person should be placed in airborne isolation room

• Maintain a distance > 3 feet if possible

Specimen Collection – Exposed Persons and Birds

• High-risk aerosol-generating procedure

• PPE recommended– Gloves– Gown– Goggles or face-shield– N95 or better respirator

How to Put on and Remove Personal Protective Equipment

(PPE)

Sequence for Donning PPE

1. Hand hygiene

2. Gown

3. N95 Particulate respirator– Perform seal check

4. Hair cover

5. Goggles or face shield

6. Gloves

Gown

• Select appropriate type and size

• Opening may be in back or front

• Secure at neck and waist

• If too small, use two gowns– Gown #1 ties in front– Gown #2 ties in back

Surgical Mask

• Place over nose, mouth and chin• Fit flexible nose piece over nose bridge• Secure on head with ties or elastic• Adjust to fit

N95 Particulate Respirator• Pay attention to size (S, M, L)• Place over nose, mouth and chin• Fit flexible nose piece over nose bridge• Secure on head with elastic• Adjust to fit and check for fit:

Inhale – respirator should collapseExhale – check for leakage around face

Eye and Face Protection• Limited human to human

transmission of H5N1 has occurred to date

• Position goggles over eyes and secure to the head using the ear pieces or headband

• Position face shield over face and secure on brow with headband

• Adjust to fit comfortably

Gloves

• Don gloves last

• Select correct type and size

• Insert hands into gloves

• Extend gloves over gown cuffs

Key Infection Control Points

• Minimize exposures– Plan before entering room

• Avoid adjusting PPE after patient contact– Do not touch eyes, nose or mouth!

• Avoid spreading infection– Limit surfaces and items touched

• Change torn gloves– Wash hands before donning new gloves

Duration of PPE Use

Surgical Masks (if N95 not available)– Wear once and discard– Discard if moist

N95 Particulate Respirators– May use just one with cohorted patients

Eye Protection– May wash, disinfect, reuse

Sequence for Removing PPE

Remove in anteroom when possible1. Gloves2. Hand hygiene3. Gown (and apron, if worn)4. Goggles5. Mask6. Cap (if worn)7. Hand hygiene

Removing Gloves (1)

• Grasp outside edge near wrist

• Peel away from hand, turning glove inside-out

• Hold in opposite gloved hand

Removing Gloves (2)

• Slide ungloved finger under the wrist of the remaining glove

• Peel off from inside, creating a bag for both gloves

• Discard

Removing A Gown1. Unfasten ties2. Peel gown away from neck and shoulder

3. Turn contaminated outside toward the inside4. Fold or roll into a bundle5. Discard

Removing Goggles or A Face Shield

• Grasp ear or head pieces with ungloved hands

• Lift away from face

• Place in designated receptacle for disinfecting or disposal

Removing a Mask• Lift the bottom elastic

over your head first

• Then lift off the top elastic

• Discard

• Don’t touch front of mask

If You MUST Reuse PPE..• Use during one shift and for one patient • Discard at the end of each shift

GOWN• Hang gown with outside facing in

MASK OR RESPIRATORS• Put the mask into the sealable bag• May touch the front of the mask, but wash

hands immediately after removing

Hand Washing

• Between PPE item removal, if hands become visibly contaminated

• Immediately after removing all PPE

• Use soap and water or an alcohol-based hand rub

Summary• Influenza transmission occurs mainly through

respiratory droplets– Contact can be prevented using PPE– Virus can be inactivated with infection control procedures– Hand washing is key

• PPE must be donned and removed appropriately to prevent contamination of wearers and environments

• Guidelines for using PPE and infection control measures for avian influenza in humans should be practiced until they are routine

Remember…Your first obligation is to protect yourself!

If you have any doubt about your safety in any situation, avoid that situation!

References and Resources• Avian influenza, including influenza A (H5N1), in humans: WHO

interim infection control guideline for health care facilitiesRevised 24 April 2006. http://www.who.int/csr/disease/avian_influenza/guidelines/infectioncontrol1/en/index.html

• Practical Guidelines for Infection Control in Health Care Facilities. SEARO Regional Publication No. 41; WPRO Regional Publication. 2004. http://w3.whosea.org/LinkFiles/Update_on_SEA_Earthquake_and_Tsunami_infection-control.pdf

• US Centers for Disease Control and Prevention. “Cover Your Cough” http://www.cdc.gov/flu/protect/covercough.htm

• Elizabeth A. Bolyard, et al. Centers for Disease Control and Prevention. Guideline for infection control in health care personnel, 1998. http://www.cdc.gov/ncidod/dhqp/pdf/guidelines/InfectControl98.pdf

This presentation based onhttp://www.cste.org/influenza/avianinfo/Module3/Module%203%20Personal%20Protective%20Equipment_Background_5-9.pptprovided by the Council of State and Territorial Epidemiologists (CSTE). CSTE is a professional association of over 1050 public health epidemiologists working in states, local health agencies, and territories.

It is part of an avian flu program available athttp://www.cste.org/dnn/ProgramsandActivities/InfectiousDiseases/RapidResponseAvianInfluenza/tabid/172/Default.aspx

Exercise 1: ScenarioWhile no human avian flu H5N1 cases have been confirmed, a highly pathogenic strain has been identified in local poultry. The virus causing this outbreak has been shown in other parts of the world to cause lower respiratory disease in humans. You are asked to lead a team sent to identify and interview people who may have been exposed to infected birds on a small farm. You do not expect your team will have direct contact with birds, but you may be near areas where the poultry were housed.

Exercise 1: QuestionsQuestion 1: Based on what you know about infection control, what Personal Protective Equipment (PPE) would you bring on this initial visit?

Question 2: If the PPE you planned to bring is unavailable, how would you proceed?

Exercise 2Scenario: You arrive at the farm to conduct interviews. You have enough PPE for your team. Government officials are already on the scene for publicity purposes; you notice none are wearing PPE. You don’t yet know if anyone on the farm has flu-like symptoms.

Question: How do you proceed? Will you conduct interviews without wearing PPE?

Exercise 3Scenario: While you are conducting an interview of a person who may have been exposed to sick poultry, the interviewee reports that she has a fever and diarrhea. You are not wearing any PPE.

Question 1: Ideally, what PPE should be worn when interviewing a symptomatic exposed person?

Question 2: How do you proceed?

Exercise 4: Scenario

There are two suspected human cases of avian influenza in a local hospital. One case was admitted directly to the hospital. The second case initially presented in the emergency room, and was admitted to the hospital after mentioning his contact with ill poultry. The hospital has put the patients in separate, private rooms. Your team has been called to interview these suspected cases.

Exercise 4: QuestionsQuestion 1: Which personal protective equipment will you wear during these interviews in the hospital setting?

Question 2: Are there other infection control measures that should be taken in this situation?