Tumour-educated Macrophages Promote Tumour Progression and Metastasis
Presented BY. General view Most common intraocular tumour in adult Most common intraocular tumour in...
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Transcript of Presented BY. General view Most common intraocular tumour in adult Most common intraocular tumour in...
Presented BYPresented BY
General viewGeneral view• Most common Most common
intraocular tumour in intraocular tumour in adultadult
• Presentation:-Presentation:- decrease VAdecrease VA VF defect VF defect
photopsia photopsia asymptomatic asymptomatic
• Signs:Signs: elevated sub elevated sub retinal oval mass, retinal oval mass, dark color, lipofuscin dark color, lipofuscin orange color, orange color, exudative RD ……. exudative RD ……. others others
InvestigationsInvestigations• USUS
• FFAFFA
• ICG >> better ICG >> better than FFAthan FFA
• CT >> extrocular CT >> extrocular extensionextension
• MRIMRI
• DopplarDopplar
• Screen for mets.Screen for mets.
TreatmentTreatment
• Depend on the size: Depend on the size: largelarge > 8mm thick > 8mm thick
> 16mm diameter> 16mm diameter
mediummedium 3.1-8mm thick 3.1-8mm thick
5-16mm diameter5-16mm diameter
smallsmall 1-3 mm thick 1-3 mm thick
>5mm diameter>5mm diameter
• Location, extent, activity, state of the other Location, extent, activity, state of the other eye & general healtheye & general health
General Roles:( COMS )General Roles:( COMS )
• Large size: enculeationLarge size: enculeation
• Medium size: plaque radiotherapy Medium size: plaque radiotherapy (iodine-125 brachytherapy)(iodine-125 brachytherapy)
• Small size: Observation ( controversy !!)Small size: Observation ( controversy !!)
>>Others mod of Rx e.g. charged >>Others mod of Rx e.g. charged particle irradiation, TTT, Laser particle irradiation, TTT, Laser photocoagulation, local resectionphotocoagulation, local resection
Prognosis:Prognosis:
• Histological features: spindel cell 45%Histological features: spindel cell 45%
epithelioid cell 5%epithelioid cell 5%
mixed cell 45%mixed cell 45%
necrotic 5%necrotic 5%
• Size: small 16%, med 32%, large 53%Size: small 16%, med 32%, large 53%
• Extrascleral extensionExtrascleral extension
• LocationLocation
• AgeAge