Preliminary Program · General Information: FALK FOUNDATION e.V. Leinenweberstr. 5 79108 Freiburg...

General Information:

FALK FOUNDATION e.V.Leinenweberstr. 579108 FreiburgGermany

Congress DepartmentTelephone: +49(0)761/1514-0Telefax: +49(0)761/1514-359E-Mail: [email protected]

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Preliminary Program

Falk Symposium 199

Highlights from Hepatology 2015: From Chronic Hepatitis to Hepatocellular Carcinoma

October 14 – 15, 2015Konzerthaus FreiburgFreiburg, Germany

Application for CME credits submitted

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Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4

Scientific Program . . . . . . . . . . . . . . . . . . . . . . . . . . 6

Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

List of Speakers, Moderators and Scientific Organizers . . . . . . . . . . . . . . . . . . . . . . . . 11

Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14

CME credits for the Falk Symposium 199 have been applied for at the European Union of Medical Specialists (UEMS) – European Board of Gastroenterology (EBG) . The number of credits awarded will be printed in the final program .

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Preface

Dear colleagues, dear friends,

On behalf of the scientific organizers, Olivier Chazouillères, Josep M . Llovet, Darius Moradpour and myself, I would like to cordially invite you to the Falk Symposium 199 entitled ”High-lights from Hepatology 2015“ . At that meeting, internationally leading experts of their respective fields will provide an update on current state-of-the-art and novel developments in Hepatology . Topics range from acute and chronic viral hepatitis, autoimmune liver disease, alcoholic and metabolic liver disease, liver cirrhosis and its complications to liver cancer .

In the tradition of the successful Falk Symposia, the program combines basic science with clinical relevant aspects . Thus, this translational update on pathogenesis, diagnosis and treatment therapy of the most important and clinical relevant liver diseases will be of interest to both, clinicians and scientists .

A special invitation is extended to young clinician scientists who can present their work in the poster sessions and will surely benefit from fruitful discussions .

We are looking forward to welcoming you for two days of excellent presentations, interesting discussions and social contacts in the wonderful city of Freiburg in the Black Forest .

With best wishes on behalf of the scientific organizers,

Robert Thimme, Freiburg


Falk Symposium 199



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Registration:Tuesday, October 13, 201516 .00 – 21 .00 hat the congress office

Scientific Organization:O . Chazouillères, Paris (France)J . M . Llovet, Barcelona (Spain) D . Moradpour, Lausanne (Switzerland)R . Thimme, Freiburg (Germany)

Congress Venue:Konzerthaus FreiburgKonrad-Adenauer-Platz 179098 FreiburgGermany

Information:Prof . Dr . Robert ThimmeInnere Medizin IIUniversitätsklinikum FreiburgHugstetter Str . 5579106 FreiburgGermanyTelephone: +49 (0) 761 / 27 03 28 00Telefax: +49 (0) 761 / 27 03 61 00E-Mail: robert .thimme@

uniklinik-freiburg .de

Official Language:English . Simultaneous translation into German .

Posters:For details see page 10

Publication Date of the Final Program: October 2015

The final program will be available on the homepage www .falkfoundation .org one week before .


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Wednesday, October 14, 2015

9.00 Welcome R . Thimme, Freiburg

Session I Viral hepatitis I

Chair: D . Moradpour, Lausanne; R . Thimme, Freiburg

9.10 History and global burden of viral hepatitis H . E . Blum, Freiburg

9.35 Hepatitis B: From molecular virology to new antiviral F . Zoulim, therapies Lyon

10.00 Hepatitis C in the era of direct antiviral therapies D . Moradpour, Lausanne

10.25 Coffee break with poster session

Session II Viral hepatitis II

Chair: D . Moradpour, Lausanne; R . Thimme, Freiburg

10.55 Chronic hepatitis D: At a stand still? M . Rizzetto, Turin

11.20 Hepatitis E virus: Time to change the textbooks! H . R . Dalton, Truro

11.45 Challenges in special populations: Co-infection, liver X . Forns, transplantation etc . Barcelona

12.10 Lunch break with poster session


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Wednesday, October 14, 2015

Session III Autoimmune liver disease

Chair: O . Chazouillères, Paris; A . W . Lohse, Hamburg

13.30 Pathogenesis of autoimmune and cholestatic liver diseases G . Hirschfield, Birmingham

13.55 Autoimmune hepatitis C . P . Strassburg, Bonn

14.20 Overlap syndromes: Classification, diagnosis and A . W . Lohse, management Hamburg

14.45 Novel aspects in the management of cholestatic liver O . Chazouillères, diseases Paris


Session IV Alcoholic and metabolic liver disease

Chair: R . Bataller, Chapel Hill; A . Geier, Wuerzburg

15.40 Pathogenesis and management of alcoholic liver disease R . Bataller, Chapel Hill

16.05 NASH: From pathogenesis to novel therapies A . Geier, Wuerzburg

16.30 Hereditary hemochromatosis: Pathogenesis, diagnosis H . Zoller, and treatment Innsbruck

16.45 End of afternoon session


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Thursday, October 15, 2015

Session V Liver cirrhosis and its complications

Chair: A . L . Gerbes, Munich; M . Rössle, Freiburg

9.00 Development and reversion of cirrhosis M . Pinzani, London

9.30 Current management of the complications of cirrhosis G . Garcia-Tsao, and portal hypertension: variceal hemorrhage, ascites, New Haven and spontaneous bacterial peritonitis .

10.00 Liver cirrhosis and kidney A . L . Gerbes, Munich


Session VI From basic science to the clinic

Chair: F . Lammert, Homburg; G . Perlemuter, Paris

11.00 Microbiota and liver disease G . Perlemuter, Paris

11.25 Genetics in liver disease F . Lammert, Homburg

11.50 Immune responses in viral hepatitis C . Neumann-Haefelin, Freiburg

12.15 Liver fibrosis: from pathogenesis to novel therapies F . Tacke, Aachen

12.40 Acute liver failure A . E . Canbay, Essen

13.05 Lunch break with poster session


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Thursday, October 15, 2015

Session VII Liver cancer: molecular pathogenesis and treatment

Chair: P . R . Galle, Mainz; J . M . Llovet, Barcelona

14.00 Presentation of Poster Prizes R . Thimme, Freiburg

14.10 Molecular pathogenesis and novel drivers J . Zucman-Rossi, Paris

14.40 Role of immunity in pathogenesis and treatment R . Thimme, of HCC Freiburg

15.10 Management of liver cancer P . R . Galle, Mainz

15.40 From emerging phase I to failing III phase trials J . M . Llovet, Barcelona


16.40 Assessment / response in HCC R . Lencioni, Pisa

17.10 Molecular pathogenesis and treatment of ICC G . J . Gores, Rochester

17.40 Surgical treatment of HCC and ICC P . E . Majno, Geneva

18.10 End of the meeting


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Poster SessionPosters will be exhibited on October 14-15, 2015 in the Konzerthaus Freiburg . The authors will be in attendance during coffee and lunch breaks on both days .

Call for PostersPlease submit your poster abstract before June 30, 2015 . Only one-page abstracts not exceeding 300 words, written in English and saved in Microsoft Word format will be accepted .

Abstracts must be submitted via our Internet Abstract Submission System (http://www .falkfoundation .org/poster) where further information regarding the submission format and the submission process will be available .

The abstracts will be selected by the scientific organizers, preference being given to those thematically related to one of the sessions of the program .

The accepted abstracts will be printed and distributed to the participants of the congress together with the documents of the meeting .

The authors will receive notification about acceptance and further instructions in July 2015 .

Contact address for further information on the poster session:

Falk Foundation e . V . Congress Department Leinenweberstr . 5 79108 Freiburg (Germany) Telephone: +49 (0)761/1514-0 Telefax: +49 (0)761/1514-359 Web address for submitting poster abstracts: http://www .falkfoundation .org/poster

For the first author of an accepted poster, expenses for accommodation (October 13 – 16, 2015) and fees for the scientific program and evening activities will be covered during the Falk Symposium 199 . Travel expenses will not be covered .

Poster PrizesThree prizes will be awarded for the best presentations . Prize winners will be presented with a certificate and prize money for e 1,500, e 1,000 and e 500, respectively . Travel expenses will be covered additionally for the first author of prize winning posters .


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List of Speakers, Moderators and Scientific Organizers

Ramon Bataller, M.D., Ph.D.UNC School of MedicineDept . of Gastroenterology and Hepatology101 Manning DriveChapel Hill, NC 27514 USAramon_bataller@med .unc .edu

Prof. Dr. Dr. h.c. mult. Hubert E. BlumInnere Medizin IIUniversitätsklinikum FreiburgHugstetter Str . 5579106 FreiburgGermanyhubert .blum@uniklinik-freiburg .de

Prof. Dr. Ali E. CanbayGastroenterologie/HepatologieUniversitätsklinikum EssenHufelandstr . 5545147 EssenGermanyali .canbay@uk-essen .de

Prof. Dr. Olivier ChazouillèresService d‘hépatologieCHU Paris Est - Hôpital Saint-Antoine184 rue du Faubourg Saint-Antoine75012 ParisFranceoliver .chazouilleres@sat .aphp .fr

Dr. Harry R. Dalton Royal Cornwall Hospital Trust European Centre for Environment and Human HealthUniversity of ExeterCornwellTuro TR1 3LJGreat Britain harry .dalton@rcht .cornwall .nhs .uk

Dr. Xavier FornsHospital Clinic of BarcelonaLiver UnitCarrer de Villarroel 17008036 BarcelonaSpainxforns@clinic .ub .es

Prof. Dr. Peter R. GalleInnere Medizin IUniversitätsmedizin derJohannes Gutenberg-UniversitätLangenbeckstr . 155131 MainzGermanypeter .galle@unimedizin-mainz .de

Guadalupe Garcia-Tsao, M.D.Professor of MedicineYale University333 Cedar Street - 1080 LMPNew Haven, CT 06520USAguadalupe .garcia-tsao@yale .edu

Prof. Dr. Andreas GeierMed . Klinik und Poliklinik IIKlinikum derUniversität WürzburgOberdürrbacher Str . 697080 WürzburgGermanygeier_a2@medizin .uni-wuerzburg .de

Prof. Dr. Alexander L. GerbesMedizinische Klinik IIKlinikum der UniversitätMünchen - GroßhadernMarchioninistr . 1581377 MünchenGermanygerbes@med .uni-muenchen .de

Gregory J. Gores, M.D.Professor of MedicineMayo ClinicDivision of Gastroenterology& Hepatology200 First Street SWRochester MN 55905USAgores .gregory@mayo .edu


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Dr. Gideon HirschfieldUniversity of BirminghamCenter of Liver ResearchInstitute of Biomedical ResearchP .O . Box 363Birmingham B15 2TTGreat Britaing .hirschfield@bham .ac .uk

Prof. Dr. Frank LammertKlinik für Innere Medizin IIUniversitätsklinikumdes SaarlandesKirrberger Str . 10066424 HomburgGermanyfrank .lammert@uks .eu

Dr. Riccardo LencioniUniversità di PisaDivision of RadiologyDepartment of OncologyVia Roma, 6756100 PisaItalyriccardo .lencioni@med .unipi .it

Prof. Dr. Ansgar W. LohseMedizinische Klinik IUniversitätsklinikum EppendorfMartinistr . 5220251 HamburgGermanyalohse@uke .de

Prof. Dr. Josep M. LlovetHospital Clinico y ProvincialUniversidad de BarcelonaDivision of Liver Diseasesc/ Villarroel no . 17008036 BarcelonaSpainjmllovet@clinic .ub .es

Prof. Dr. Pietro E. MajnoHepatobiliary CenterDiv . of Visceral Surgeryand TransplantationGeneva University Hospitals1211 GenevaSwitzerlandpietro .majno@hcuge .ch

Prof. Dr. Darius MoradpourCentre Hospitalier Universitaire VaudoisDiv . of Gastroenterology& Hepatology BB07-2400Rue du Bougnon 441011 LausanneSwitzerlanddarius .moradpour@chuv .ch

PD Dr. Christoph Neumann-HaefelinInnere Medizin IIUniversitätsklinikum FreiburgHugstetter Str . 5579106 FreiburgGermanychristoph .neumann-haefelin@ uniklinik-freiburg .de

Prof. Dr. Gabriel PerlemuterHôpital Antoine-Béclère157 rue de la Porte de Trivaux92140 ClamartFrancegabriel .perlemuter@abc .aphp .fr

Prof. Dr. Massimo PinzaniUCL Insitute for Liver andDigestive HealthRoayl Free Hospital U3Pond StreetLondon NW3 2QGGreat Britainm .pinzani@ucl .ac .uk


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Prof. Dr. Mario RizzettoAzienda OspedalieraS . Giovanni Battista di TorinoDivisione di GastroenterologiaCorso Bramante 88/9010126 TorinoItalymrizzetto@cittadellasalute .to .it

Prof. Dr. Martin RössleGastroenterologePraxiszentrum für Gastroenterologie und EndokrinologieBertoldstr . 4879098 FreiburgGermanymartin-roessle@t-online .de

Prof. Dr. Christian P. StrassburgMedizinische Klinik IUniversitätsklinikum BonnSigmund-Freud-Str . 2553127 BonnGermanychristian .strassburg@ukb .uni-bonn .de

Prof. Dr. Dr. Frank TackeMedizinische Klinik IIIUniversitätsklinikum AachenPauwelsstr . 3052074 AachenGermanyftacke@ukaachen .de

Prof. Dr. Robert ThimmeInnere Medizin IIUniversitätsklinikum FreiburgHugstetter Str . 5579106 FreiburgGermanyrobert .thimme@uniklinik-freiburg .de

Dr. Heinz ZollerUniversitätsklinik InnsbruckGastroenterologie/HepatologieAnichstr . 356020 InnsbruckAustriaheinz .zoller@i-med .ac .at

Prof. Dr. Fabien ZoulimLyon UniversityHepatology DepartmentINSERM U1052151 Cours Albert Thomas69003 LyonFrancefabien .zoulim@inserm .fr

Prof. Dr. Jessica Zucman-RossiUniversité Paris DescartesHopital Européen Georges PompidouDepartment of OncologyINSERM U674/116227 rue Juliette Dodu75010 ParisFrancejessica .zucman-rossi@inserm .fr


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General InformationPrior to the opening of the congress

Falk Foundation e . V . Telephone: +49 (0)761/1514-0Congress Department Telefax: +49 (0)761/1514-359Leinenweberstr . 5 E-Mail: symposia@falkfoundation .de79108 Freiburg (Germany)

Congress OfficeDuring Falk Symposium 199

Konzerthaus Freiburg Telephone: +49 (0)175/7795327Konrad-Adenauer-Platz 179098 FreiburgGermany

Opening Hours:Tuesday, October 13, 2015 16 .00 – 21 .00 hWednesday, October 14, 2015 8 .00 – 18 .00 hThursday, October 15, 2015 8 .30 – 15 .00 h

Congress FeesScientific program of the Falk Symposium 199 e 200 .00Students and residents e 100 .00

* * * OR * * *

Day ticket e 120 .00Students and residents e 60 .00

Employees of pharmaceutical or other companies and their guestsFalk Symposium 199 e 600 .00

The congress fees include:- Welcome Evening on October 13, 2015- Refreshments during coffee breaks- Lunch on October 14-15, 2015- A copy of the abstract volume- Underground parking at the „Konzerthaus Freiburg“


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RegistrationCongress registrations must reach the Falk Foundation e . V . by July 31, 2015 at the latest . After receipt of the registration form, each participant will be provided with an invoice/confirmation . On presentation of this confirmation at the congress office in Freiburg participants will receive the congress folder containing name badges, admission tickets and abstract volume .In the event of registration cancellations, a handling fee of e 20 .00 will be deducted from the refund . All participants will receive a written confirmation of attendance at the end of the meeting .

Admission to Scientific EventsFor admission to scientific events your name badge should be clearly visible .

Congress ReportThe official congress report of the Falk Symposium 199 “Highlights from Hepatology 2015: From Chronic Hepatitis to Hepatocellular Carcinoma” will be published in English in the first half of 2016 by Karger, Switzerland . Orders for this book at a reduced subscription price of e 35 .00 can be placed at the Congress Office during the congress in Freiburg .

Congress Short ReportThe congress short report of the Falk Symposium 199-200 will be published by the Falk Foundation e .V . with number FSR 199-200 in the first half of 2016 .


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AirportsEuroAirport Basel-Mulhouse-Freiburg http://www .euroairport .com/en/

Frankfurt International Airport www .frankfurt-airport .com

Airport Transfer http://www .freiburger-airportservice .de/en/

Train Connections http://www .bahn .com

Directions to Konzerthaus FreiburgFrom the North or the South, take A5 autobahn/motorway Frankfurt-Basel along the Rhine Valley, exit ”Freiburg Mitte“ . Stay on the autobahn feeder road ”Mitte“ until exit ”Konzerthaus Freiburg“ (10 min .), follow signs to the Konzerthaus Freiburg .

A81 Stuttgart-Singen autobahn/motorway or B31 (Höllental), Donaueschingen, Titisee-Neustadt . Go through Freiburg on the Schwarzwaldstrasse, this becomes Schreiberstrasse, direction of the autobahn feeder road ”Mitte“ . There are road signs to the Konzerthaus Freiburg .

Connections to the French and Swiss autobahn/motorway networks . 950 parking places in the underground car park at the Konzerthaus and central train station (Hauptbahnhof) .


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Directions to the Konzerthaus Freiburg


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General Information:

FALK FOUNDATION e.V.Leinenweberstr. 579108 FreiburgGermany

Congress DepartmentTelephone: +49(0)761/1514-0Telefax: +49(0)761/1514-359E-Mail: [email protected]

VP1

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1-11

/201

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ü

Preliminary Program

Falk Symposium 199



Application for CME credits submitted

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Preliminary Program · General Information: FALK FOUNDATION e.V. Leinenweberstr. 5 79108 Freiburg...

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