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  • General Information:

    FALK FOUNDATION e.V. Leinenweberstr. 5 79108 Freiburg Germany

    Congress Department Telephone: +49(0)761/1514-0 Telefax: +49(0)761/1514-359 E-Mail: symposia@falkfoundation.de www.falkfoundation.org

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    Preliminary Program

    Falk Symposium 199

    Highlights from Hepatology 2015: From Chronic Hepatitis to Hepatocellular Carcinoma

    October 14 – 15, 2015 Konzerthaus Freiburg Freiburg, Germany

    Application for CME credits submitted

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    Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4

    Scientific Program . . . . . . . . . . . . . . . . . . . . . . . . . . 6

    Posters . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

    List of Speakers, Moderators and Scientific Organizers . . . . . . . . . . . . . . . . . . . . . . . . 11

    Information . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 14

    CME credits for the Falk Symposium 199 have been applied for at the European Union of Medical Specialists (UEMS) – European Board of Gastroenterology (EBG) . The number of credits awarded will be printed in the final program .

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    Preface

    Dear colleagues, dear friends,

    On behalf of the scientific organizers, Olivier Chazouillères, Josep M . Llovet, Darius Moradpour and myself, I would like to cordially invite you to the Falk Symposium 199 entitled ”High- lights from Hepatology 2015“ . At that meeting, internationally leading experts of their respective fields will provide an update on current state-of-the-art and novel developments in Hepatology . Topics range from acute and chronic viral hepatitis, autoimmune liver disease, alcoholic and metabolic liver disease, liver cirrhosis and its complications to liver cancer .

    In the tradition of the successful Falk Symposia, the program combines basic science with clinical relevant aspects . Thus, this translational update on pathogenesis, diagnosis and treatment therapy of the most important and clinical relevant liver diseases will be of interest to both, clinicians and scientists .

    A special invitation is extended to young clinician scientists who can present their work in the poster sessions and will surely benefit from fruitful discussions .

    We are looking forward to welcoming you for two days of excellent presentations, interesting discussions and social contacts in the wonderful city of Freiburg in the Black Forest .

    With best wishes on behalf of the scientific organizers,

    Robert Thimme, Freiburg

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  • Falk Symposium 199

    Highlights from Hepatology 2015: From Chronic Hepatitis to Hepatocellular Carcinoma

    October 14 – 15, 2015 Konzerthaus Freiburg Freiburg, Germany

    5

    Registration: Tuesday, October 13, 2015 16 .00 – 21 .00 h at the congress office

    Scientific Organization: O . Chazouillères, Paris (France) J . M . Llovet, Barcelona (Spain) D . Moradpour, Lausanne (Switzerland) R . Thimme, Freiburg (Germany)

    Congress Venue: Konzerthaus Freiburg Konrad-Adenauer-Platz 1 79098 Freiburg Germany

    Information: Prof . Dr . Robert Thimme Innere Medizin II Universitätsklinikum Freiburg Hugstetter Str . 55 79106 Freiburg Germany Telephone: +49 (0) 761 / 27 03 28 00 Telefax: +49 (0) 761 / 27 03 61 00 E-Mail: robert .thimme@

    uniklinik-freiburg .de

    Official Language: English . Simultaneous translation into German .

    Posters: For details see page 10

    Publication Date of the Final Program: October 2015

    The final program will be available on the homepage www .falkfoundation .org one week before .

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    Wednesday, October 14, 2015

    9.00 Welcome R . Thimme, Freiburg

    Session I Viral hepatitis I

    Chair: D . Moradpour, Lausanne; R . Thimme, Freiburg

    9.10 History and global burden of viral hepatitis H . E . Blum, Freiburg

    9.35 Hepatitis B: From molecular virology to new antiviral F . Zoulim, therapies Lyon

    10.00 Hepatitis C in the era of direct antiviral therapies D . Moradpour, Lausanne

    10.25 Coffee break with poster session

    Session II Viral hepatitis II

    Chair: D . Moradpour, Lausanne; R . Thimme, Freiburg

    10.55 Chronic hepatitis D: At a stand still? M . Rizzetto, Turin

    11.20 Hepatitis E virus: Time to change the textbooks! H . R . Dalton, Truro

    11.45 Challenges in special populations: Co-infection, liver X . Forns, transplantation etc . Barcelona

    12.10 Lunch break with poster session

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    Wednesday, October 14, 2015

    Session III Autoimmune liver disease

    Chair: O . Chazouillères, Paris; A . W . Lohse, Hamburg

    13.30 Pathogenesis of autoimmune and cholestatic liver diseases G . Hirschfield, Birmingham

    13.55 Autoimmune hepatitis C . P . Strassburg, Bonn

    14.20 Overlap syndromes: Classification, diagnosis and A . W . Lohse, management Hamburg

    14.45 Novel aspects in the management of cholestatic liver O . Chazouillères, diseases Paris

    15.10 Coffee break with poster session

    Session IV Alcoholic and metabolic liver disease

    Chair: R . Bataller, Chapel Hill; A . Geier, Wuerzburg

    15.40 Pathogenesis and management of alcoholic liver disease R . Bataller, Chapel Hill

    16.05 NASH: From pathogenesis to novel therapies A . Geier, Wuerzburg

    16.30 Hereditary hemochromatosis: Pathogenesis, diagnosis H . Zoller, and treatment Innsbruck

    16.45 End of afternoon session

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    Thursday, October 15, 2015

    Session V Liver cirrhosis and its complications

    Chair: A . L . Gerbes, Munich; M . Rössle, Freiburg

    9.00 Development and reversion of cirrhosis M . Pinzani, London

    9.30 Current management of the complications of cirrhosis G . Garcia-Tsao, and portal hypertension: variceal hemorrhage, ascites, New Haven and spontaneous bacterial peritonitis .

    10.00 Liver cirrhosis and kidney A . L . Gerbes, Munich

    10.30 Coffee break with poster session

    Session VI From basic science to the clinic

    Chair: F . Lammert, Homburg; G . Perlemuter, Paris

    11.00 Microbiota and liver disease G . Perlemuter, Paris

    11.25 Genetics in liver disease F . Lammert, Homburg

    11.50 Immune responses in viral hepatitis C . Neumann-Haefelin, Freiburg

    12.15 Liver fibrosis: from pathogenesis to novel therapies F . Tacke, Aachen

    12.40 Acute liver failure A . E . Canbay, Essen

    13.05 Lunch break with poster session

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    Thursday, October 15, 2015

    Session VII Liver cancer: molecular pathogenesis and treatment

    Chair: P . R . Galle, Mainz; J . M . Llovet, Barcelona

    14.00 Presentation of Poster Prizes R . Thimme, Freiburg

    14.10 Molecular pathogenesis and novel drivers J . Zucman-Rossi, Paris

    14.40 Role of immunity in pathogenesis and treatment R . Thimme, of HCC Freiburg

    15.10 Management of liver cancer P . R . Galle, Mainz

    15.40 From emerging phase I to failing III phase trials J . M . Llovet, Barcelona

    16.10 Coffee break with poster session

    16.40 Assessment / response in HCC R . Lencioni, Pisa

    17.10 Molecular pathogenesis and treatment of ICC G . J . Gores, Rochester

    17.40 Surgical treatment of HCC and ICC P . E . Majno, Geneva

    18.10 End of the meeting

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    Poster Session Posters will be exhibited on October 14-15, 2015 in the Konzerthaus Freiburg . The authors will be in attendance during coffee and lunch breaks on both days .

    Call for Posters Please submit your poster abstract before June 30, 2015 . Only one-page abstracts not exceeding 300 words, written in English and saved in Microsoft Word format will be accepted .

    Abstracts must be submitted via our Internet Abstract Submission System (http://www .falkfoundation .org/poster) where further information regarding the submission format and the submission process will be available .

    The abstracts will be selected by the scientific organizers, preference being given to those thematically related to one of the sessions of the program .

    The accepted abstracts will be printed and distributed to the participants of the congress together with the documents of the meeting .

    The authors will receive notification about acceptance and further instructions in July 2015 .

    Contact address for further information on the poster session:

    Falk Foundation e . V . Congress Department Leinenweberstr . 5 79108 Freiburg (Germany) Telephone: +49 (0)761