PPT PSYCH AMYGDALA
Transcript of PPT PSYCH AMYGDALA
![Page 1: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/1.jpg)
The Amygdala
By: Alinka, Harel, Vjosa
![Page 2: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/2.jpg)
General Information; Function
![Page 3: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/3.jpg)
General Information; Location
![Page 4: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/4.jpg)
Study 1• Aim: Determine the volume in the amygdala in a series of brains
post-mortems• Procedure:
– Amygdala volume was estimated using point-counting in both hemispheres of brains of 10 male and 8 female patients with schizophrenia
– Had a comparison group of 9 male and 9 female post-mortems without neuropsychiatric disorder
• Results: No significant reduction of amygdala found
• Implications: Significant volume reduction isn’t not consistent feature in schizophrenia
![Page 5: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/5.jpg)
Study 2
• Aim: Examine neural activity in amygdala during episodes of mania. • Procedure:
– 9 manic participants & 9 healthy comparison subjects underwent fMRI while performing a neuropsychological paradigm known to activate the amygdala
– Experimental Task: participants see faces displaying affection– Control task: geometric forms– Goal: Match them to one of two similar images presented at same time
• Results: Manic participants had significantly increased activation in the left amygdala and reduced bilateral activation in the lateral orbit frontal cortex relative to the comparison participants.
• Implications: Increased activation in the amygdala and decreased activation in the orbitofrontal cortex may represent disruption of a specific neuroanatomic circuit involved in mania. These brain regions may be implicated in disorders involving regulation of affect.
![Page 6: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/6.jpg)
Study 3• Aim: Investigate what happens in the brain during and after phobia
treatment• Procedure:
– Examined brain activity of 18 people w/ social phobia as they spoke in front of a group using PET scans
– 1/3 of the participants received 9 weeks of cognitive-behavioral therapy– 1/3 received the selective serotonin reuptake inhibitor Citalopram and 1/3
received no treatment. – Participants were tested again, using the same public speaking task, at 9
weeks and again after one year.
• Results: Activation in the amygdala and related cortical areas at 9 weeks could predict which people's symptoms would improve after one year
![Page 7: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/7.jpg)
Dysfunction
![Page 8: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/8.jpg)
![Page 9: PPT PSYCH AMYGDALA](https://reader036.fdocuments.net/reader036/viewer/2022082920/55566027d8b42aa41e8b54b4/html5/thumbnails/9.jpg)