POWERWULF CLUSTERS
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Transcript of POWERWULF CLUSTERS
POWERWULF CLUSTERS World’s Leading Provider of
Turn-key Compute Solutions for NGS / Bioinformatics
ABOUT US Founded in 1989
Over 1000 PowerWulf Clusters Delivered World Wide
350+ PowerWulf Clusters Dedicated Compute
Appliances for NGS / Bioinformatics
Mission Statement
Tier 1 Manufacturing & Support at Commodity Price
Custom Configured Products Include
Turn key PowerWulf Compute Clusters
RaidStation Storage Solutions
High Performance Workstations & Servers
LIFE SCIENCE SUCCESS Selected by Roche / 454 and CLCbio as OEM Hardware Provider
Over 60% of ALL WORLDWIDE data off GS FLX Titanium Platform is analyzed on PSSC Labs Platform
Roche’s Success in this space linked directly to PSSC Labs PowerWulf Cluster solution CLCbio is a leader in genomics software solutions
Certified our PowerWulf Clusters and Servers Compatible with Life Technologies’ Bioscope & Illumina’s Casava Applications
Pacific Biosciences considering PSSC Labs as OEM Hardware Provider
Recent LARGE Cluster Wins Western Kentucky University – 5000+ Cores
PSSC Labs Selected after evaluation of Dell, HP, IBM OpenX.org – 7000+ Cores
PSSC Labs Selected after evaluation of Dell, HP, IBM MIT / Harvard / HHMI Neuroimaging Center
Largest GPU Cluster at MIT
Revolutionary POWERSERVE DUO TI2000 Perfect Cluster Building Block Tool-Free Design Power Saving Eco Friendly Features World Wide Support & Maintenance
NGS/BIOINFORMATICS EXPERIENCE Partnerships w/ leading Sequencing Platform Providers
Roche / 454 OEM Provider of GS FLX Titanium Cluster (www.pssclabs.com/roche)
Life Technologies Certified Cluster Solutions w/ Bioscope Preconfigured
Illumina Certified Cluster / Server Solutions w/ Casava Preconfigured
Pacific Biosciences Potential OEM Proider of off line cluster for new RS platform
Ion Torrent Certified Workstation w/ Ion Torrent Software
CLC Bio Selected as OEM Hardware Provider of Genomics Machine / Factory
WHY OUR SUCCESS IN NGS Delivery Fully Functional / Turn Key Systems
Biologist are typically not system administrators. Just need a system that works out of the box.
Superior Knowledge & Support You will have direct communication with the PSSC Labs Cluster
Engineer that built, tested and configured the system with your applications.
Our Remote Assist support provides greater more responsive support than any other vendor
We Understand Your Business Seqwright needs a knowledgeable cost effective hardware
provider that ensures they deliver their customer results on time, every time. Our systems are considered the industry’s most reliable with a failure
rate >0.01%. This is a direct result of our superior testing procedure
PERFORMANCE PSSC Labs Runs Benchmarks Provided
by Application to Certify SystemsTypical benchmarks include small and large
data sets for all pipeline steps (mapping, assembly, alignment)
Example WT Run is one of three stress tests we run to
certify our clusters for BioscopeResults: DURATION= 6 hours 36 minutes 44
secs Configuration: 8 Core (2.67 Ghz) / 48GB
Memory)
PERFORMANCE Information obtained from end users
Illumina / Casava UCI Irvine
We are sequencing Drosophila (fruity fly) samples. The genome is approximately 1.2 x 108 base pairs.
One lane of paired-end, 75bp data from an Illumina GA2 machine gives about 25X coverage of a genome. Roughly 35 million pairs of reads per lane or 2* 75 *35e6 =
5.25e10 base pairs of data. We sequence 3 lanes per sample. Pipeline involves a lot of
custom software to do our analyses, and we can entirely process a single sample in about 12 hours. This is much more than simply doing the alignments
System Configuration PowerServe Duo T2400 (Single SMP System) 8 Processor Cores / 2.4 Ghz 128 GB System Memory 40 TB USABLE High Speed Storage Space
PERFORMANCE Information obtained from end users
Illumina / Casava St. Radbound University
“Mapping one exome sample to the human reference takes about 8.5 hours using Bioscope 1.3”
System Configuration PowerWulf Cluster 64 Processor Cores / 2.53 Ghz / 8 Cores Per Node 4 GB Memory Per Core
PERFORMANCE CLC Bio Genomics Factory Comparison
PSSC Labs is OEM Provider of Genomics Factory
156 Cores (12 cores per node / 2.53 Ghz)4 GB of Memory Per CoreStated Performance on Website
Mapping, whole human genome, 15x coverage: 32 Full Human Genomes Per Week (2 x 100 basepair Illumina GA – data
Whole human transcirptome analysis (RNA-seq): 600 Samples per week (130 million 50bp SOLiD reads