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Potentiality of GPS Approach to Leishmaniasis in Hyper- endemic area of Bangladesh Bumpei Tojo 1,...
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Transcript of Potentiality of GPS Approach to Leishmaniasis in Hyper- endemic area of Bangladesh Bumpei Tojo 1,...
Potentiality of GPS Approach to
Leishmaniasis in Hyper-endemic area of
Bangladesh
Bumpei Tojo1, Makoto Ito2, Mohammad Sohel Samad2, Emi Ogasawara1
1.University of Tokyo, Japan (Long term (2013-2015) project expert of JICA)
2.Aichi Medical Univ., Japan
Background of this study
Part of JICA (/SATREPS) Kala-Azar Project
http://www.satreps-kalaazar.com/en/index.html
Framework of Kala-azar Project Develop Diagnostic tools
Actual status and mechanisms of Kala-azar and PKDL
Vector control
Content of this presentation
• Introduction of our mass screening activity targeting school children which perform the measurement of urinary antibody and the position information collecting using GPS (Global Positioning System) in Mymensingh district.
KEY WORDS: Kala-azar, Epidemiology, Surveillance system, Global
Positioning System (GPS), GIS Analysis
Mymensingh
Number of patients(2011)
persons/year
426737
262
Kala-azar endemic area (2011)** Information based patient number registered at government hospital
・ It is said number of kala-azar patients decline from year to year in Bangladesh.
・ Southern part of Mymensingh (Fulbaria, Trishal, Gafargaon Upazila) is still relatively high endemic area of kala-azar according to the government data.
・ Annual patients number of these three upazila is 737, 426, 262. They are 14.8, 9.1, 5.1 person of patients per population of 10,000. It is still more than elimination goal (less than 1.0).
・ These data source is hospital base patient number. We guess another result will come by active survey…
49
36
Actual Mass screening Activity (2013-2014) in Mymensingh, Trishal Upazila
Establishment the efficient and costless active survey “system” for kala-azar.
1. Measurement of urinary antibody : To find out infection of kala-azar by quick and easy operation..
3. Distribution of GPS logger: It is possible to collect mass of the position information effectively.
2. Paperless registration “system” : Using tablet device with data-entry program instead of Questionnaire paper. It drastically saves time and labor of whole process of activity.
Mass screening “system” targeting school children
=
Workflow of Mass screening activity at primary school in trishal
Using tablet device with data-entry program for student registration, hand over a cup and GPS logger
After registration, each student is back with urine specimen, specimen is stored inside tube.
This is a movie of actual mass screening at trishal. Using tablet device and bar-cord system, it becomes possible to manage data linkage fast and easily between student registration information, urinalysis result, collected position data using GPS logger.
After introducing this Paperless “system”, very few staff can handle around 300-400 student mass screening within 1 day.
Measurement of urinary antibody of collected specimen using ELISA at SK KRC
From last survey (Mar 2014), we success to start measurement of urinary antibody using SK KRC laboratory facility
↑ Detected ELISA positives are shown green color
Total number of school children examined
Urine ELISA positives Number of Primary School (PS)
2013 Aug(8/25 - 9/9)
1,352 6 (0.4%) 6 (In the west part of Trishal Upazila)
2014 Mar(3/4 - 3/16)
1,171 78 (6.6%) 4*(In the east part of Trishal Upazila)
Sub total* 2,523 84 (3.3%) 10
* (East Part)PS1 = 7 / 208 (3.3%)PS2 = 30 / 305 (9.8%)PS3 = 15 / 309 (4.8%)PS4 = 26 / 349 (7.4%)
Result of mass screening conducted 2013 August and 2014 March in Trishal Upazila
1. Number of ELISA positives between two survey duration was very different (16.5 times differ).
2. Between 4 PS of survey in March in the east part of the upazila, its positives differs from 3.3% to 9.8 % (about 3 times).
0 10km
5
West Part (6 PS): 0.4%
East Part (4 PS): 6.6%
Trishal Upazila Legend
Primary School (PS)Upazila boundary
Area coverage of mass screening
Image: ALOS-AVNIR-2 (False Color)
← Spatial inequality of ELISA positive has clearly observed in this result.
PS1 (3.3%)
PS2 (9.8%)
PS3 (4.8%)
PS4 (7.4%)
【Time series tracking log data of GPS 】
Analyzing the position information (extracted from GPS logger) of each registered student on GIS.
Finding “more” micro hot spot of kala-azar endemic using GPS data logging and Tracking Analysis on GIS
Before Tracking
After Tracking
0 5km
2.5
2014 MarchTotal screening=1171GPS data collection success=1008Total Positive=78GPS data collection success=66
Urine Antibody Unit(Negative)
(Positive)
PS1 (3.3%)
PS4 (7.4%)
PS2 (9.8%)
PS3 (4.8%)
0 1km
0.5
Urine Antibody Unit(Negative)
(Positive)
Endemic Foci
PS2 (9.8%)
PS3 (4.8%)
0 1km
0.5 Urine Antibody Unit(Negative)
(Positive)
Endemic Foci
PS1 (3.3%)
PS4 (7.4%)
Conclusion- Developing the mass screening surveillance system
targeting school children were achieved until now. This system consist of measure urinary antibody and collect the position information using GPS (Global Positioning System). Assist by e-registration system is essential from viewpoint of labor saving in this system(huge field data can handle within few days by few staff).
- From previous 2 times surveillance results, there is a possibility that can be constructed monitoring system to identify the micro-scale hot spot of kala-azar endemic using GIS, helpful for evaluation of kala-azar elimination situation.
- Find possibility of application of this system for another neglected tropical infectious disease surveillance (malaria, filaria, etc).