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DISPLAY PERSONNEL ADVERTISEMENTS

For rates, deadlines, and information about fraction-al display ads (all ads 1/6 page and larger) and allMarketplace listings of available products and serv-ices, contact:

Schwago AocIates1515 Broadwy

New York, NY 10036Telephone: 212-730-1050

FAX: 212M82-3725

CONDITIONS: Personnel advertising is acceptedonly with the understanding that the advertisers donot discriminate among applicants on the basis ofrace, sex, religion, age, color, national origin, hand-icap, or sexual preference. Science reserves theright, at its discretion, to decline to publish adver-tisements submitted to it and to decline classifica-tions which it considers misleading.

POSITIONS OPEN

The Department of Surgery at Stanford UniversitySchool of Medicine is con ucting a search for an expe-

rienced academic leader in pediatric surgery to head the

Division of Pediatric Surgery. Candidates should beexperienced academic surgeons with an appropriate

record of clinical and laboratory investigation. 1The levelof appointment will be at the ASSOCIATE PROFES-SOR or PROFESSOR rank based on the candidate'squalifications. Stanford University is committed to increasingrepresentation ofwomen and members of minority groups on

itsfaculty and particularly encourages applicationsfrom suchcandidates. Interested applicants should write to: Chair-man, Department of Surgery, MSOB Room X-228,Stanford University School of Medicine, Stanford,CA 94305.

ASSISTANT PROFESSOR OF BIOLOGY. Ten-ure-track, academic year appointment commencing 26August 1991 to participate in a quality undergraduateprogram. Teaching courses in immunology will be re-

quired as well as other classes in the incumbent's area ofexpertise. Preference will be given to individuals withspecialization in the areas of embryology, parasitology,bacteriology, general biology, and in particular hematol-ogy, and the ability to advise medical technology stu-dents. Commitment to quality teaching and direction ofundergraduate research is required. Salary commensuratewith qualifications.

Qualification: Doctoral degree in biological sciences(or related field) required; evidence of teaching excel-lence desired.Submit letter of application, resume, and three letters

of reference to: Office of Employee Relations, LakeSuperior State University, A tion Building,Sault Ste. Marie, MI 49783. Applications deadline: 10May 1991.

An Equal Opportunity/Affirmative Action Employer.

CONSERVATION ECOLOGISTASSISTANT PROFESSOR

The University of Georgia's Department of Zoology,in conjunction with the Institute of Ecology, announcesa tenure-track position for a conservation ecologist. Thesuccessful can'idate will play a major role in a new

graduate program in "Conservation Ecology and Sus-tainable Development" and should develop research andteaching programs in conservation and population ecol-ogy and natural history. Starting date is negotiable. Tobe assured of consideration, please send, by 17 May1991, curriculum vitae, statement ofresearch plans, threeletters of reference, and relevant reprints to: Chair,Conservation Search Committee, Zoology Depart-ment, University of Georgia, Athens, GA 30602.Telephone: 404-542-3310.

The University of Georgia is an Equal OpportunitylA4frmative Action Institution.

CELL BIOLOGIST

The Department ofVeterinary and Comparative Anat-omy, Pharmacology, and Physiology, College of Veteri-nary Medicine, Washington State University, invitesapplications or nominations for a tenure-track position atthe ASSISTANT/ASSOCIATE PROFESSOR level.The duties of the position include: the development of a

vigorous, independent research program employingmodern methods of cell and/or molecular biology; in-volvement in graduate training; and participation in

teaching veterinary cell biology, developmental biology,and/or microscopic anatomy to D.V.M. students. Areasof research in the department include neurobiology,reproductive endocrinology, hemostasis, exercise, andcardiovascular physiology. Qualifications: Ph.D. and ap-propriate research and teaching experience. Rank andsalary will be commensurate with qualifications. Earlieststarting date is 1 September 1991.

Written applications must include curriculum vitaeand the names, addresses, and telephone numbers ofthree references. Applications, nominations, or inquiriesshould be sent to: Dr. J. W. Harding, Department ofVeterinary and Comparative Anatomy, Pharmacolo-gy, and Physiology, College of Veterinary Medicine,Washington State University, Pullman, WA 99164-6520. Review ofapplications will begin 1 July 1991, andwill continue until the position is filled.

Washington State University is an Affirmative Action!Equal Opportunity Educator and Employer.

19 APRIL 1991

POSITIONS OPEN

BIOLOGIST. Fall of 1991, ASSISTANT PRO-FESSOR, tenure track, to teach human life science andenvironmental science to nonmajors, and at least two

upper-level courses to majors; developmental biology,immunology, or another course in area of expertise,complementary to our curriculum. Ph.D., commitmentto excellent teaching required; preference to candidateswith teaching experience. Send curriculum vitae, tran-

scripts, and three letters ofrecommendation to: Dean B.Richardson, West Viinia Wesleyan College, Buck-hannon, WV 26201. Application review begins 3 May1991. You may call Dr. Katharine Gregg, Chair,Department of Biology, at 304-473-8124. Equal Op-

portunity/Affirmative Action Employer.

ASSISTANT PROFESSORVERTEBRATE BIOLOGY

Search continued. Tenure-track position availablestarting September 1991. Hollins College, a private

4-year liberal arts college for women, seeks a vertebratebiologist to teach undergraduate courses in general biol-ogy, comparative anatomy, embryology, and histology.Teaching load is two courses per semester. Experience inscanning EM is desirable. Accepted candidate is expectedto develop a research program involving undergraduatestudents. Ph.D. required. Curriculum vitae, statement ofteaching and research interest and experience, transcript,copies of significant publications, and three letters ofrecommendation should be sent to: Dr. Harriet Gray,Chair, Department of Biology, Hollins College, P.O.Box 9616, Roanoke, VA 24020 by 1 May 1991. EqualOpportunity Employer.

TRANSPLANTATION IMMUNOLOGISTLOYOLA UNIVERSITY OF CHICAGO

The Loyola University of Chicago cardiac transplan-tation program has an immediate opening for an immu-nologist to establish a high quality basic research pro-

-arm in transplantation immunology. A tenure track willDC ted in the Departments of Medicine and Micro-bio og and Immunology at the ASSISTANT ORASSOCIATE PROFESSOR levels. Candidates shouldhave a Ph.D. and a record of established research in theareas of allograft rejection, transplantation tolerance,and/or allograft vascular disease. Candidates must bewilling to participate in graduate and medical studentsteaching. While the successful candidate is expected toobtain extramural funding, the salary is not dependentfrom grant funds. Please submit curriculum vitae, twocopies of relevant papers, description of research goals,and three supporting letters to:

Maria Rosa Costanzo-Nordin, M.D.Medical Director

Cardiac Transplant ProgramLoyola University of Chicago

Maywood, IL 60153

UNIVERSITY OF CALIFORNIASANTA CRUZ (UCSC)

The Santa Cruz campus of the University of Californiais seeking a FULL PROFESSOR in ENVIRON-MENTAL TOXICOLOGY with an emphasis onaquatic systems, with an outstanding research record inone of the area of (i) characterization, transport and fateof contaminants in surface or groundwater (particularlywith a strong analytical expertise in trace analysis), (ii)microbial remediation, (iii) biochemical toxicology, or(iv) ecotoxicology of natural systems. The appointee isexpectd to maintain an active research program andteach graduate and undergraduate courses. The appoint-ment is the first of several in environmental toxicology.Depending upon training and research interests, theappointee initially will be a member of the Departmentof Chemistry, Earth Sciences, Marine Sciences, Biologyor Environmental Studies. Rank: Professor step I to V,Salary range: $43,100 to $72,200, commensurate withqualifications and experience. Minimum qualifications:Ph.D. or equivalent in any of the above fields. Outstand-ing research, and teaching record appropriate to the levelof appointment. Applicants should submit curriculumvitae, statement of research and teaching interest andexperience, and names of four referees to: Environmen-tal Toxicology Search Committee, Institute ofMarineSciences, Uniersity of California, Santa Cruz, CA95064, by 15 May 1991; please refer to provision#211-901 in your reply. Position available: fall of 1991.UCSC is an Afnative Aaionq Opportunity Emploer.

PERSONNEL PLACEMENT 457

Biocides FormulationChemist

A leading manufacturer of biocides, with laboratories inEurope and the U.S., has an immediate opening for aformulation chemist. The successful candidate will defineand develop, to commercial introduction, a variety ofbiocide formulations for industrial applications.Applications of special interest include paint-filmmildewcides, wood preservatives, and preservation ofemulsions and metal-working fluids.We are looking for a scientist with a B.S. or higher degreein chemistry or a related science. You should have at leastfive years of experience in formulating industrial biocides,and a record of technical success in product introductions.You must also be conversant with a broad range ofcommerically available biocide products and their activeingredients. Finally, you should have strong organizationaland interactive skills necessary for effective collaborationwith marketing groups and customers worldwide. Thisposition may involve relocation to the U.S.We offer a highly competitive salary and benefits program,including relocation assistance. Our staff enjoys modernresearch facilities and numerous resources forprofessional advancement. This position will enable youtodevelopnewbiocidestechnologywith majorcommercialimpact through innovative, open-ended research. Forconfidential consideration, please forward your resumeto:

Ref. 46118Paul BanfieldM. S. L. International32 Aybrook StreetLondon W1M 3JL U.K.

OR

P.O. Box 65119Washington, DC20035-5119 U.S.A.

a;BEHAVIORAL SCIENTIST : >::...:.....:.: .-.

OR''''NOVA PHARMACEUTICAL CORPORATION, a leading '-RR>R'.RResearch

who will be responsible tor developing and per

tRR orming behavioral tests in its CNS Research Division. R...RR Qualified candidates should hove a PhD with 2+ R.-,*RRR years' relevant experience (including supervision) with --R.working knowledge pharmacological principles.

...Knowledge ot anxiolytic drug-discrimination and/or ... ........ ..

medications is valuable as are excellent oral and written

>experience.......

..preterred. .. ..

NOVA PHARMACEUTICAL CORPORATION a smallea

Reseandgrowing company providing a challenging work ..environment. We offer a competitive salary andper*mbenetits includes health(including.

prescription plan). lite and dental insurance; proit

shar ing; savings stock

.tiono ssistonce. . ...*.:..: For immediate consideration, please send

.. ..resume

tCORP Personnel-91-004, Freeport Centre,a

mcBaltimorsMDi21224-6522. islanequal opportunitytemployer offering a smoke-tree work environment.

NOVA PHARMACEUTICAL CORPORATIONis a small

s '.:i-Zvs.'.: .... #r'.., > ":R '' ' - Z ......................................... - .an grwn ...omp.any providin a chlegn >work...,..... . , 0...

VP/Senior Director, Biological Sciences

We invite applications for the position of V.P./SeniorDirector, who reports directly to the Senior/ice President forResearch and Development and leads our Biological Sciencegroups (Cell Biology, Molecular Biology, Pharmacology andEnzymology) in drug discovery.

We seek an individual with more than 8 years of postdoctoral experience, preferably including pharmaceutical industryexperience, who has outstanding expertise and a record of highlyproductive achievement. Excellent leadership and communicationskills are essential.

ImmunoPharmaceutics is a growing development stage

integrated pharmaceutical company based on antibody directeddesign technology for the cardiovascular and inflammation/immune regulation markets. We offer an exciting workingenvironment, competitive salaries and benefits, equity participa-tion and a highly desirable Southern California location.

Please send your resume in confidence to:

ImmunoPharmaceutics, Inc., Recruitment, Dept. JB, 11011 Via

Frontera, San Diego, CA 92127. An affirmative action/equalopportunity employer.

|99| IMMUNOPHARMACEUTICS, INC.A Synbnotcs Company

PHARMACETICALTOXICOLOGICPATHOLOGIST

offmann-La Roche, an established internation-al leader in the research and development ofpharmaceutical products, has a challengingand rewarding opportunity on our generalpathology team in the Department of Toxicolo-

gy and Pathology.You will participate in the preparation of protocols,

supervise necropsies, conduct histopathologic examina-tions, generate pathology reports and co-author toxicologyreports of preclinical drug safety assessment studies con-ducted according to the GLPs to be submitted to regulato-ry agencies in support of registration of new drugs. Also,conduct/collaborate in investigations to elucidate thenature of toxic/therapeutic effects of drugs; and enhancethe managerial processes of drug discovery and develop-ment.

To qualify, you must be a DVM or MD Pathologist spe-cializing in pharmaceutical toxicology/experimental thera-peutics; and have a record of success in a multi-disci-plinary environment.We offer an excellent compensation, benefits, bonus and

relocation package. Please send your resume, indicatingpresent salary (those without this information will not beacknowledged), to: Mrs. Eleanor M. Malone, Staffing andEmployee Services, Department EM091ZR, Hoffmann-LaRoche Inc., Nutley, New Jersey 07110. We are an equalopportunity employer.

@ Hoffmann-La RocheWorking Today For A Healthier Tomorrow

A-

I%_ anummoop,

THE OHIO STATE UNIVERSITY

The Ohio State University is seeking applicationsand nominations for Vice President for AgriculturalAdministration and Executive Dean of the College ofAgriculture. Major responsibilities include: serving as

academic dean of the College of Agriculture, includingthe School of Natural Resources and the AgriculturalTechnical Institute, and administrative responsibilityfor the Ohio Agricultural Research and DevelopmentCenter and the Ohio Cooperative Extension Service.Candidates should have academic experience and a

record of administrative/leadership ability generallyconsonant with the complexity of a large land-grantuniversity. The candidate must be qualified fortenured appointment at the rank of professor.

Nominations and letters of interest with pertinentsupporting materials should be sent to:

Mr. Jerry H. BakerLamalie Associates, Inc.3340 Peachtree Rd., N.E.Atlanta, Georgia 30326

DEADLINE FOR APPLICATIONS: May 15,1991 or

until a desirable candidate is selected.

The Ohio State University is an Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL SCIENTISTThe Bioresearch Department of SmithKline Beecham Anim-

al Health is seeking a Postdoctoral Scientist to perform in-

vestigative studies on infections by Borreila burydorferi in

animals and humans. The specific area of research will focus

on the immune response to infection, host/spirochete or

tick/spirochete interactions of Lyme Disease or vaccinedevelopment.

The appointment is temporary full time for a periodof two years and is part of a research agreement between

SmithKline Beecham Animal Health and the Centers for

Disease Control (CDC) in Fort Collins, CO. The successfulcandidate will work within the Division of Vector-Borne In-

fectious Diseases at the CDC in Fort Collins, CO.

Applicants should send curriculum vitae, includingrelevant reprints, and the names and addresses of three ref-

erences to: Leonard W. Mayer, Ph.D., P.O. Box 2087, Fort

Collins, CO 80522. An Equal Opportunity EmployerM/F/H/V.

SmuthKline BeechamAnimal Health

St. John's UniversityCOLLEGE OF PHARMACY &

ALLIED HEALTH PROFESSIONSThe Department of Pharmaceutical Sciences,College of Pharmacy & Allied HealthProfessions, at St. John's University seeks to filla tenure-track position at the assistant or associateprofessor leveL Applicants must Possess a Ph.D.Responsibilities include undergraduate andgraduate courses as well as an active researchprogram. Preference will be given to candidateswith a background in cell biology, molecularbiology, or pharmacology. The departmentpossesses excellent facilities and all the necessarysupport services for research. Moderninstrumentation, an AAALAC accredited animalfacility, and tissue culture laboratories areavailable. The college provides a supportiveenvironment for scientists beginning their careerin basic research. Application letters withcurriculum vitae, statement of research interestsand names of three references should be sent to:Dr. Armit Kapoor,Professor & Chairman,Department of

Pharmaceutical Sciences,St. John's University, KA,^,tab B1 lltot IN&IN

Jamaica, NY 11439.St. John's is an Affirmative Action/Equal Opportunity Employer - M/F.

4-

THOMAS JEFFERSONUNIVERSITY

JEFFERSON CANCER INSTITUTECarlo M. Croce, M.D., Director

FACULTY POSITIONS IN IMMUNOLOGY. Several faculty ap-pointments are currently available in the recently expanded De-partment of Microbiology and Immunology. We invite applica-tons from new and established investigators for full time tenure-track positions at any academic rank. Individuals with strongresearch interests in any area of immunology will be considered.Investigators with research programs in Molecular Immunologyare particularly encouraged to apply. The Department currentlyhas research interests in transplantation immunology, autoim-munity, immunogenetics, cell-cell interactions, neuroimmunol-ogy, immunoparasitology, tumor immunology, cytokines, andimmunoregulation. The research environment is excellent andconducive for active interactions within the Department and withother members of the Jefferson Cancer Institute. The Universityitself is located in the vibrant historical downtown area of Phila-delphia. Please send curriculum vitae, research plans, and thenames and addresses of three references to:

Dr. Robert KorngoldDepartment of

Microbiology and ImmunologyJefferson Medical College

1020 Locust StreetPhiladelphia, PA 191076799

We are committed to a s e- frwe environmentThomas Jefferson Unverity is an Affimatie Action-

Equal Opportunity Employer

POSITIONS OPENr

The Department of Surery at Stanford UniversitySchool of Medicine is conducting a search for an expe-rienced academic leader in vascular surgery to head theDivision of Vascular Surgery. Candidates should beexperienced academic surgeons with an appropriaterecord of clinical and laboratory investigation. The levelof appointment will be at the ASSOCIATE PROFES-SOR or PROFESSOR rank based on the candidate'squalifications. Stanford University is committed to increasingrepresentation ofwomen and members of minority groups onitsfaculty and particularly encourages applicationsfrom suchcandidates. Interested applicants should write to: Chair-man, De t of Surgery, MSOB Room X-228,Stanfrd Univsity School of Medicine, Stanford,CA 94305.

PROFESSOR. The University of California, LosAngeles (UCLA), Department of Kinesiology, Divisionof Life Sciences, in the College of Letters and Science,invites applications for a cellular electrophysiologist inthe area of vision research. This is a full professortenured position, and candidates are expected to have adistinguished, extramurally funded research record in thephysiology of photoreceptors, as well as the physiologyand pharmacology of ciliary body epithelium. The ap-pointeewill be expected to teach at both the undergrad-uate and Applicants must have a Ph.D. orM.D. degree, and the salary will be commensurate withqualifications. This appointment will begin 1 July 1991,subject to the availability offunds. Deadline for receipt ofapplications is 15 May 1991. Submit your curriculumvitae, representative reprints, and a cover letter thatincludes the names and addresses of at least three indi-viduals who may be contacted for letters of reference to:Ronald F. Zernicke, Ph.D., Department of Kinesiol-ogy, 2859 Slichter Hall, UCLA, Los Angeles, CA90024-1568. The University of Calfornia is an EqualOpportunity/AJIrmative Action Employer.

ASSISTANT PROFESSORANATOMY/NEUROBIOLOGY

Applicants are invited for a tenure-track position in theDepartment ofAnatomy and Cell Biology, University ofNorth Dakota School ofMedicine. Applicants must havea Ph.D., M.D. or equivalent with at least 2 years ofpostdoctoral training and research experience in neuro-biology, cell biology, or related areas. The successfulapplicant will be expected to carry on a vigorous extra-murally funded research program in his/her respectivefield. Applicants should be willing toassist in teaching aninterdepartmental neuroscience course for medical stu-dents and to contribute to teaching in an undergraduateparamedical anatomy course. The successful candidatewill also be expeced to make a substantial contributionto the departmental graduate program. Review of appli-cations will begin 1 May 1991, and continue until theposition is filled. Send curriculum vitae, descriptions ofresearch and teacinfg experience, and three Fetrs ofreference to: Dr. Edward C. Carlson, Chairman, De-partment ofAnatomy and Cell Biology, University ofNorth Dakota School ofMedicine, Grand Forks, ND58202. The University of North Dakota is an EqualOpportunity/AlrmativeAction Employer and invites appli-cationsfrom all qualified individuals.

ENVIRONMENTAL SCIENCE: DIRECTOR ofCenter fur Environmental Programs. The objectives ofthis 5-year program, which is funded by the Departmentof Energy, are to infuse an environmental/waste manage-ment focus into cm'stin curricula and to increase partic-ipation of minority andeducationally disadvantaged stu-dents in technical fields. Previous experience in managinsuch programs, as well as in teaching, is preferredResponsibilities for the position include managing the

program, developing and teaching courses in environ-mental science, community outreach, and grant writing.Xavier University is a small, predominantly black, Cath-olic, liberal arts institution. A Ph.D. in environmentalscience or equivalent is required. Salary is commensuratewith experience. Position begins immediately. Send letterof application, curriculum vitae, and three letters ofrecommendation by 15 May 1991 to:

Dr. Howard MielkeChair, Search Committee

Center for Environmental ResearchXavier University of LouisianaNew Orleans, LA 70125

Affirmative Action/Equal Opportunity Employer.

POSITIONS OPEN

BIOMOLCU NMR SOFTWARE R&D

By combining scientific rigor and programming excel-lence, BIOSYA is a recognized leader in the field ofcomputer-aided molecular design. We are currently de-veloping an integrated system for elucidating molecularstructures from NMR within BIOSYM's molecular mod-eling environment. The package includes multidimen-sional NMR data processing and analysis, semi-automat-ed resonance assignment, structure generation, andrefinement tools.We have an opportunity for an innovative, creative

scientist with experience in multidimensional homonu-dear and heteronudear NMR of proteins and nucleicacids, as well as extensive programming skills. The indi-vidual selected will be responsible for designing software,writing and implementing code within the BIOSYMenvironment, scientific validation, and developmentalresearch.A Ph.D. in chemistry, biochemistry, or physics, with

expertise in NMR spectroscopy is required. Also re-

quired is experience developing and using 2D/3D NMRdata processing and analysis sofare and using automat-

ed resonance assignment strategies in Proteis and nu-

cleic acids. Fluency in Fortran and "C, experience with

UNIX and graphic programming are desirable.If you are interested in joining a progressive, scientific

team, send your detailed rvsume, transcript copies, andthree letters of recommendation to: BIOSYM Technol-ogies, Inc., 10065 Barnes Canyon Road, San Diego,CA 92121. Equal Opportunity Employer, M/F/H/V.

CYTOGENETICS TECHNOLOGIST. The cyto-

genetics laboratory of The University of Nevada Schoolof Medicine Genetics Network has an immediate open-

ing available for an NCA-certified or -eligible individualwith a minimum of 1 year of full-time experience inclinical cytogenetics. Our laboratory is now in its thirdyear ofdevelopment and is growing rapidly. Our genetics

network is a nonprofit group established to providegenetic services to the state of Nevada and includesspecialists in medical genetics, genetic counseling, andcytogenetics. This position represents an excellent oppor-tunity to be a part of a high quality, fill service facility.The Reno area has much to offer, from Tahoe skiing to

international level entertainment, and all in an un-

crowded setting. Salaries are competitive and commen-

surate with experience. Benefits are excellent and Nevadahas no state income tax. Interested candidates shouldsend resumes or call: A. Dean Stock, Ph.D., AssociateProfessor Pathology/Laboratory Medicine, Directorof Cytogets, University of Nevada School ofMedicine, 888 Willow Street, Reno, NV 89502.Telephone: 702-786-1969; FAX: 702-786-6256.

The U.S. Environmental Protection Agency (EPA),Environmental Research Laboratory-Duluth, located inDuluth, Minnesota, is accepting applications for a super-visory research aquatic biologist to serve as CHFOF PREDICIVE TOXICOLOGY RESEARCHBRANCH. Branch conducts and manages both intra-mural and extramural research on computational meth-ods to predict the toxic behavior of pollutants. Thebranch chief supervises a multidisciplinary team of phys-iologists, toxicologists, biochemists, and modelers. Thebranch supports EPA with formal programs in toxicitymechanisms, metabolism, pharmacokinetics extrapola-tion, and quantitative structure-activity relationships.

Requirements include a Ph.D. or equivalent in biolo-gy, biochemistry, or toxicology. This position will beavailable in ApriMay 1991, at a salary range of $52,406to $68,129. Turther information may be obtained bycontacting Dr. Steven Broderius at 218-7205574.

Write: U.S. EPA, 6201 Congdon Boulevard, Du-luth,MN 55804, Attention: Sherry Linder, to requestapplication forms.

Position open only to U.S. citizens.The U.S. EPA it an Equal Opportunity Employer.

UNIVERSITY OF COLORADOSCHOOL OF PHARMACY

HEAD, DIVISION OF PHARMACEUTICALSCIENCES. The division consists of 16 full-time facultyand has a strong basic research orientation. Qualifiedcandidates are invited to submit a letter of interest,curriculum vitae, and names of five references by 31 May1991 to: Louis Diamond, Dean, University of Colo-rado School ofPharmacy, Boulder, CO 80309-0297.The University of Colorado Health Sciences Center is com-mitted to Equal Opportunity and Affirmative Action.

460

POSITIONS OPEN

KENYA FIELD DIRECTORTHE SCHOOL FOR FIELD STUDIES (SFS)

Unique field program in wildlife management andconservation needs skilled, experienced leader for semes-ter and summer programs. Fifteen to thirty highly mo-tivated students earn full academic credit at spectacularfield station. Advanced degree, East Africa experience,teaching, leadership, and organizational skills required.Annual base is up to $35,000 (including $5,000 roomand board support). Send detailed letter, resume andtelephone numbers of three or more references to: KSSearch, SFS, 16 Broadway, Beverly, MA 01915.Inquiries: 508-927-7777. FAX: 508-927-5127. SFSis an Equal Opportunity Employer.

DIRECTORSOUTH AFRICAN

ASTRONOMICAL OBSERVATORY

Applications or nominations are invited for the post ofdirector of the South African Astronomical Observatory(SAAO) which will become vacant when Professor M.W. Feast retires from this position. The SAAO is oper-ated as a national facility by the Foundation for ResearchDevelopment (FRD), a statutory body which also fundsand promotes scientific research in South African univer-sities. The base of the SAAO is in Cape Town (at theformer Royal Observatory) and the main telescopes areat Sutherland, Cape Province. The largest telescope is a1.9m reflector though funding is being sought for a 3.5mtelescope. There is a wide range of auxiliary instruments.Besides the research program carried out by its staff, theSAAO provides facilities for astronomers from the na-tional and international community. Further details ofthe SAAO staff and facilities can be obtained from: TheDirector, SAAO, P.O. Box 9, Observatory 7935,Cape, South Africa. Applications or nominationsshould be sent before 31 August 1991 to: The Presi-dent, Foundation for Research Development, P.O.Box 2600, Pretoria 0001, South Africa, from whomdetails of the post can be obtained. Appointments to allposts at SAAO are made on the basis oftmerit and irrespectiveof race, sex, or creed. It is expected that the new directorwill assume office in early 1992.

DIRECTORMOLECULAR DIAGNOSTIC LABORATORYDEPARTMENT OF MEDICAL GENETICSOREGON HEALTH SCIENCE UNIVERSITY

A faculty position is available for an M.D. or Ph.D.molecular geneticist with experience in DNA diagnosticsand Boad certification or eligibility in biochemical/molecular genetics. This facility will complement a strongstate-wide program in clinical genetics, well-establishedPh.D. and M.D. training programs, and existing clinicalcytogenetics and clinical biochemical genetics laborato-nes. The position will also allow development of anindependent research program. Letters of inquiry shoulddescribe past experience and professional goals, andinclude curriculum vitae with names of three referees.Send by 30 June 1991 to: Nancy G. Kennaway, D.Phil., Department of Medical Genetics, L-473, Ore-gon Health Sciences University, Portland, OR07201. Telephone: 503-494-8392; FAX: 503-494-7645. Equal Opportunity/Affirmative Action Employer.

DNA CHEMISTRY FACILITY MANAGER. Aposition is available at Washington University in St.Louis for a qualified individual to manage the BiologyDepartment's Integrated DNA Chemistry Facility. Thefacility houses a DNA synthesixer, HPLC, FPLC, fer-menter, computing densitometer, radioanalytic scanner,and other advanced instruments for shared use. Theprimary responsibility will be to run the DNA srnthesiz-er and to manage and facilitate the use of e otherinstruments by departmental researchers. The personhired also will have the opportunity to engage part-timein either research or teaching. Requirements include asuitable background in DNA biochemistry and ability touse modem instruments for automated protein and DNAmanipulations. Experience with computer hardware andprogramming would be advantageous. To apply, send aletter indicating interest in this position and curriculumvitae and arrange to have three letters of reference sentto: Professor Roy Curtiss III, Chairman, DepartmentofBiology, Campus Box 1137, One Brookings Drive,Washington Umversity, St. Louis, MO 63130. Wash-ington University is an Equal Opportunity/Affirmative Ac-tion Employer.

SCIENCE, VOL. 252

SAMUEL ROBERTS NOBLEFOUNDATION

PLANT BIOLOGY RESEARCH FELLOWSHIPSNOBLE FOUNDATION- SALK

JOINT PROGRAMApplications are invited for two

Noble Foundation Fellowships forpost-doctoral research in PlantMolecular Biology. These Fellowshipsare a key element in a collaborativeprogram between the Plant BiologyDivision, Noble Foundation,Ardmore, Oklahoma, directed by Dr.Richard A. Dixon, and the PlantBiology Laboratory, The SalkInstitute for Biological Studies, LaJolla California, directed by Dr.Christopher J. Lamb.

Research topics will be in the areaofbiochemical, molecular and geneti-cal analysis ofsignal transductionpathways for induction ofplantdefense gene expression by elicitorsand infection. The Fellowships are forthree years beginning October, 1991.Eighteen months will be spent in

each laboratory.Please send resume and three

letters ofrecommendation to: Dr.CJ. Lamb, The Salk Institute for

Biological Studies, P.O. Box85800, San Diego, CA 92186-5800.Telephone (619) 453-4100, ext.106. Equal opportunity employerMIF/V/IH

The UpJohn Company, a recognized leader in pharmaceutical research anddevelopment, currently has several excellent opportunities for Postdoctoral Scientistsin our Upjohn Laboratories Division.

MOLECULAR VIROLOGY: Study the molecular mechanisms of herpessimplex virus morphogenesis andDNA replication with the goal of identifying noveltargets for antiviral chemotherapy. Thesuccessfulcandidatewillhaveexperience andbackground in molecular biology, virology plus solid knowledge of standard proteinbiochemistry and enzymology techniques.

MOLECULAR RECOGNITION and PROTEIN BINDING: Developand use epitope and random sequence gene libraries as a tool to study the molecularbasis ofbioaffinity interactions and as a source ofnovel recognition molecules for useas peptide mimetics, receptor probes, bioafflnity ligands, and templates for drugdesign. Experience/strong interest inthe areas ofreceptorbiochemistry, immunologyor bioaffinity chromatography preferred.For these positions, we are seeking highly-motivated individuals with a recent Ph.D.in a related discipline. Appointments are for one year, renewable for a second. The

Upjohn PRS Program reflects our commitment to stimulatec new scientific thinking.to provide an excellent training environment for our PRS scientists along with averycompetitive salary and benefits package. Qualified candidates are invited to forwardtheir CV and cover letter describing education, research experience, publications,interests, objectives and availability date to: THE UPJOHN COMPANY, CORP.RECRU1TING/PRS PROGRAM 900659-019, 7000 PORTAGE ROAD,KALAMAZOO, MI 49001 USA. Refer to PRS Position Code 900659-019 in yourcorespondence. An Equal Opportunity Employer M/F.

Our Commitmnt to ScientfcEcellenw c Contiues...

Director of R&DSan Francisco Bay Area

Development Stage Pharmaceuti-cal Compony, developing smallmolecule anti-viral (HIV, Herpes)and onti-cancer NCEs, is looking fora Director of Research and Devel-opment with minimum 5 years ofpharmaceutical development expe-rience. Job requires experiencewith pharmaceutical project man-agement functions and with thecoordination of outside contract re-sources and academic collobora-tions. Famillority with research ononcogenes, steroid-reloted recep-tors and/or other zinc finger con-taining proteins an asset. R Ph.D.degree and experience in medici-nal chemistry, enzymology, phor-mocology, virology or cancer biolo-9g would be most useful, althoughother backgrounds will be consid-ered. Salary will be dependent onbackground and experience. Gen-erous stock participation possible.Possibility to begin work on a part-time basis. Current San FranciscoBay area residents favored. Pleasesend resume to SoBridge Rsso-cotes, Inc., 2160 St. Andows Rd.,Half Moee Say, CA 94019. 1-

a-

1

POSITIONS OPEN

DIRECTOR, CENTER FOR BIOLOGICSEVALUATION AND RESEARCH

The Food and Drug Administration is recruiting forthe director, Center for Biologics Evaluation and Re-search, located in Bethesda, Maryland. The position is inthe senior executive service with a salary range of$87,000 to $104,600. The director, Centeor Bio ogicsEvaluation and Research, directs a staff of over 500physicians, scientists, and support personnel engaged inresearch and regulatory activities concerned with biolog-ical products and blood and blood products. Applicantsmust have: an M.D. degree from an approved medicalschool or a Ph.D. or equivalent degree in a relatedbiological, biomedical, or physical science; experiencewith the innovation, resear and development, produc-tion, risk or benefit analysis, utilization, and regulation ofbiologicals and blood and blood products. He/she mustbe abl to direct and lead a complex, diversified medicalor scientific organization; effectively deal with key indi-viduals in the federal and state governments, the medicaland academic communities, professional and scientificorganizations, consumer groups, and industry; and im-plement employment and career opportunities for minor-ities, women, handicapped, and special interest groups. Itis desirable that candidates have research or clinicalachievements; demonstrated background in the clinicalpharmacology of human drugs, biologicals, and bloodand blood products; demonstrated background in bio-logicals and blood and blood products.

If you are interested and want to be considered, sendcurriculum vitae or SF-171, Application for FederalEmployment, to: Jeylene Wood, Division of HumanResources Management, Food and Drug Adminis-tion, Parklawn Building, Room 4B-09, 5600 FishersLane, Rockville, MD 20857.

Ifyou need more information, you may call Dr. MaryAnn Danello collect on 301 443-6776.

This position can also be filled by current commis-sioned officers of the U.S. Public Health Service, or byformer officers willing to rejoin the corps.

Applications will be accepted until 31 May 1991.An Equal Opportunity Employer.

FDA is smoke-free.

Department ofHuman Genetics, University of Mich-igan, is seeking a tenure-track FACULTYMEMBER ingene mapping and the molecular biology of humandisease. Send resume, statement ofresearch interests, andnames of three references to: Thomas D. Gelebrter,M.D., Department ofHuman Genetics, University ofMichigan Medical School, Ann Arbor, MI 48109-0618. Affirmative Action/Equal Opportunity Employer.

THE UNIVERSITY OF CALGARYFACULTY POSITIONS IN

CELLULAR/MOLECULAR IMMUNOLOGYThe University of Calgary Faculty of Medicine invites

applications for academic positions at the ASSISTANTPROFESSOR rank or higher for research in cellular ormolecular immunology. Qualifications include a Ph.D.,M.D. or equivalent, and interest and experience inimmunology at the cellular or molecular level, particular-ly in the characterization of autoantigen at the molecularlevel, and molecular and cellular immunology related topathogenesis of type I diabetes. Opportunities will beavailable for graduate and medical school teaching. Rankand salary commensurate with qualifications and experi-ence.The successful candidates will be expected to compete

for salary and establishment grant support from theAlberta Heritage Foundation for Medical Research orthe Medical Research Council, and will have 75% oftimeprotected for research.

In accordance with Canadian immigration requirements,priority will be given to Canadian citizens and permanentresidents of Canada. The University of Calgary has anEmployment Equity Program and encourages applicationsfrom all qualified candidates, including women, aboriginalpeople, visible minorities, and people with disabilities.

Submit complete curriculum vitae, statement of re-search and goals, and three letters of reference by 30 June1991, to:

Dr. Ji-Won YoonProfessor and Director

Julia McFarlane Diabetes Research CenterThe University of Calgary3330 Hospital Drive, N.W.

Calgary, Alberta T2N 4N1, Canada

POSITIONS OPEN

FACULTY POSITIONS IN NEUROBIOLOGYTHE UNIVERSITY OF TEXAS

SOUTHWESTERN MEDICAL CENTER

The University of Texas Southwestern Medical Centerat Dallas is establishing a Neuroscience Program, whichwill be housed in new research buildings now underconstruction. The Department of Cell Biology and Neu-roscience seeks applications for nine tenure-track posi-tions at the level of ASSISTANT, ASSOCIATE, ORFULL PROFESSOR. Applicants must have a relevantPh.D. or M.D. degree and at least 2 years of appropriate

postdoctoral training, and show evidence of a firmcommitment to a career in independent research. We are

particularly interested in considering individuals whowish to apply the techniques of biochemistry, biophysics,electrophysiology, genetics, or molecular biology to fun-damental probIems in cellular neurobiology. Responsi-

bilities will also indude teaching of medica and graduatestudents after the first year of employment. An applicant

should send curriculum, vitae, a brief description of

proposed research, and either a list of references or threeletters of references to:

Neuroscience Search CommitteeDepartent of Cell Biology and Neuroscience

University of Texas Southwestern Medical Center5323 Harry Hines Boulevard

Dalla, 75235-9039An Equal Opportunity/Affirmative Action Employer.

PEPPERDINE UNIVERSITY

FACULTY POSmON. Animal cell biology or ani-mal physiology. Applications are invited for a two-

semester, nontenure-track position to begin in late Au-gust of 1991. Subject to budgetary considerations, theappointment may be extended to 12 months and may beconverted to a full-time, tenure-track position in 1992.The visiting appointment may be made at either thejunior or senior level. The successful candidate will teachlecture/laboratory courses in biology for nonmajors and a

course for majors in his/her area of expertise. The Ph.D.and a commitment to undergraduate teaching are re-

quired. The department operates a strong program ofresearch for undergraduates, and the candidate should becapable of dirc undergraduate students in indepen-dent research projects. Pepperdine is an independentChristian university under the control of a self-perpetu-atine Board of Regents and is related to the Churches ofChrist. Submit letter of application containing a state-ment of teaching philosophy, names and adds ofthree references, and curriculum vitae to: Dr. BenneotHutchinson, Natural Science Division, PepperdineUniversity, Malibu, CA 90263. An Equal OpportunityEmployer.

FACULTY POSITIONUNIVERSITY OF CALIFORNIA, IRVINE

The Department of Physiology and Biophysics invitesapplications for a faculty position at the ASSISTANTPROFESSOR (tenure track) level commencing as earlyas September 1991. We are seeking candidates with theability to define a significant research area in eukaryoticcell physiology, using moder techniques of cell biology,molecular biology, biochemistry, or biophysics. Exam-ples of research interests would include cell signaling,differentiation and growth control, regulation of geneexpression, intracellular processing an sortin of bio-molecules, membrane formation and turnover, and therelationship of molecular structure to biological function.The position also involves teaching of medical andgraduate students. We will begin considering applica-tions starting 1 June 1991. Send curriculum vitae, a briefresearch description, and the names of three referees to:Michael D. Cahalan, Chairman, Department ofPhys-iology and Biophysics, University of California, Ir-vine, CA 92717.The University of Calfornia, Irvine, is an Affirmative

Action/Equal Opportunity Employer.

DOCTORATE, any field considered. Mature atti-tude, excellent teaching ability, congenial personality,and professional presence necessary. We train you forintensive laboratory instruction of surgeons. Permanentinstruction site in St. Louis. Some travel required. Not a

sales position. Salary: $40,000. Write for applicationinformation to: Director, Midas Rex Institute, 2929Race Street, Fort Worth, TX 76111. New applicantsonly, please.

462

POSITIONS OPEN

FACULTY POSMONImmediate opening for a senior tenured or a junior

tenure-track position in a newly formed interdepartmen-

tal Molecular Medicine Program at the University of

Massachusetts Medical Center. Rank will be commensu-

rate with ability and experience. The appointment will bein one of the basic science departments. The laboratories

for the program are housed in a new building that

contains approximately 80,000 square feet of modern

research space. Core facilities for tissue culture, mediapreparation, DNA synthesis, protein sequencing and

peptide synthesis, fluorescence-activated cell sorting, andtransgenic mice are available. The position will be highly

competitive with regard to start-up funds, laboratoryspace, and salary.The program seeks an individual of outstanding re-

search potential in the broadly defined area of eukaryoticmolecular biology. Potential areas of interest include, butare not exclusive to, transcriptional regulation, RNAprocessing, oncogenes, and developmental biology. Ap-plicants should send curriculum vitae, statement of re-

search interests, and names of three references to: Dr.Michael P. Czech, Director, Program in MolecularMedicine or Dr. Michael Green, Search CommitteeChairman, University of Massachusetts Medical Cen-ter, 373 Plantation Street, Worcer, MA 01605.

An Equal Opportunity/Alflrmative Action Employer.

MOLECULAR GENETICISTPSYCHOPHARMACOLOGIST

Mayo Clinic/Mayo Medical School invites applicantsfor a FACULTY POSITION in the Department ofPsychiatry and Psychology, in close collaboration withmembers in the Department of Pharmacology and/or theDepartment of Biochemistry and Molecular Biology.Candidates should have primary interests in major psy-chiatric disorders and be pursuing these interests with themethods of molecular genetics and/or molecular pharma-cology. M.D. and clinical training in psychiatry aredesirable but not required. Mayo will provide generousspace and start-up funds in addition to an attractivepackage of salary and benefits. Academic rank will bedetermined by qualifications; established investigatorsare also encouraged to apply. Submit curriculum vitaewith names and addresses of three or more references to:Toshihiko Maruta, M.D., Chairperson of SearchCommittee, Department of Psychiatry and Psycholo-gy, Mayo Medical School, Rochester, MN 55905. AnEqual Opportunity/Afllnative Action Employer.

Faculty Openings INSTRUCTOR: Faculty of De-partment of Clinical Nutrition, University of TexasSouthwestern Medical Center. Applicant must havePh.D. and minimum of l-year fellowship. The applicantmust be trained in both lipid physiology and molecularbiology and have the ability to bridge the gap betweenmolecular-based and physiological-based research studiesin the area of cholesterol/triglyceride metabolism, expe-rience with tracers of dietary fat metabolism required,ability to perform DNA haplotype analysis highly desir-able. Other responsibilities will include prepanng curric-ula and teaching undergraduate students in the Depart-ment of Clinical Nutrition and medical students in theCenter ofHuman Nutrition. Participation in departmen-tal and intradepartmental lectures and conferences willalso be required. Send inquiries, curriculum vitae, andcover letter to: Scott M. Grundy, M.D., Ph.D., Direc-tor, Center for Human Nutrition, University ofTexas Southwestern Medical Center, 5323 HarryHines Boulevard, Dallas, TX 75235-9052. Please donot telephone. The University of Texas SouthwesternMedical Center is an Equal Opportunity Employer.

INTERDISCIPLINARY (RESEARCH PLANTPATHOLOGIST/PLANT PHYSIOLOGIST). Lo-cated at the U.S. Department of Agrculture (USDA),Forest Service, Southern Forest Experiment Station,Southern Hardwoods Laboratory, Stoneville, Mississip-pi. Develops delin to minimize disease losses inintensively cultured and multi-use natural stands ofsouthern hardwoods. Emphasis is on developing hazardrating systems and biological and chemical controls forhardwood declines, oak wilt in live oak, and otherimportant pests. Salary ranges from $31,116 to $44,348per year, based on qualifications. Applicants must possessat least a master's degree. Contact: Dr. Jame Solomonat 601-686-7218 or Dr. Walter A. Hough at 504-589-3003. The USDA is an Equal Employment Oppor-tunity Employer.

SCIENCE, VOL. 252

POSITIONS OPEN

INDEPENDENT SCIENTIST

The Neurobiology Laboratory, part of the Neuro-science Branch of the National Institute on Drug Abuse,Addiction Research Center, wishes to enhance its effortsin elucidating molecular and cellular mechanisms relevantto addition by recruiting an independent investigatorwith interests and expertise complementing existing pro-grams in molecular pharmacology, molecular neurobiol-ogy, and brain imaging. Individuals with expertise in: (i)protein biochemistry (e.g., defining activity-dependentpost-transitional modifications of neuronal proteins orstructures of drug receptors, and interest in establishingenhanced protein/peptide biochemical facilities); or (ii)cell biology (e.g., ofdrug neurotransmitter receptors andrelated second messengers) are especially encouraged toapply. The successful candidate will lead a unit or labo-ratory, depending on experience, with staffand resourcesavailable to take a leadership position in the field. Federalsalary and benefits are competitive. M.D. and/or Ph.D.(bioogy, pharmacology) and U.S. citizenship required.Applicants are encouraged to apply to:

Brian Butters, Neuroscience Search CommitteeAddiction Research Center

P.O. Box 5180Baltimore, MD 21224

The ARC is an Equal Opportunity/Affirmative ActionEmployer, M/F/H/V, and is smoke- and drug-free.

PART-TIME LECTURERS, East/West Marine Bi-ology Program. For 1991-1992 and future years, part-time faculty positions available fall quarter (at FridayHarbor Laboratories, Washington), to teach (i) marinebirds and mammals, (ii) phycology, (iii) oceanography;winter quarter (Discovery Bay, Jamaica) (i) tropicalterrestrial ecology, (ii) biology of fishes. Expenses plusstipend-research encouraged. Please send curriculumvitae and letter of interest with names of three referencesas soon as possible to: Dr. Trish Morse, Marine ScienceCenter, Northeastern University, East Point, Nahant,MA 01908. FAX: 617-581-6076.

Northeastern University is an Equal Opportunity/Affir-mative Action/Title IX Employer.

LIPID BIOCHEMISTRY/MOLECULAR BIOL-OGIST. Position is available in the Eicosanoid Biochem-istry Workgroup of the Laboratory of Molecular Bio-physics which studies trachidonic acid and linoleic acidmetabolism by prostaglandin H synthase and lipoxygen-ases. The research involves the application of biochemis-try, chemistry, and molecular biology to the study of thestructure, function, and expression of these enzymes.These studies require the knowledge and expertise mlipid and/or protein chemistry with experience in thebiosynthesis of prostaglandms and related lipids. Someexpertise in molecular biology desirable. General require-ments: Applicants must have a Ph.D. or equlvalentdegree in biochemistry, cell biology, molecular biology,physiology, pharmacology, or closely related field, andshow evidence of ability to carry out independent re-search. Candidates with up to 6 years of postdoctoralresearch experience will be considered. For more infor-mation, contact: Dr. Thomas E. Eling at 919-541-3911. For prompt consideration, send cover letter indi-cating area of interest, curriculum vitae, and three lettersof reference by 20 May 1991 to: Mr. Bruce Wiggins(Code HNV30), National Institute ofEnvironmentalHealth Sciences, Personnel Office, P.O. Box 12233,Research Triangle Park, NC 27709. NIH is an EqualOpportunity Employer.

LABORATORY SCIENTIST m. Full-time posi-tion in the nutrition laboratory is available at the Uni-versity of Maryland Eastern Shore (UMES), PrincessAnne, Maryland. Applicants must have knowledge of

field and desire to conduct research in the areas ofnutrition and metabolism. Ph.D. preferred; will considerlower degrees with research expenence. Starting salary is

$25,937 per year. Letters of application, induding threeletters of reference and curriculum vitae, should be sentto: Director of Personnel, University of MarylandEastern Shore, Princess Anne, MD 21853. Closingdate for applications is 30 May 1991. Candidates must beprepared to demonstrate that they may legally accept employ-ment in the United States. UMES is anAfflrmativeAction/Equal Opportunity Employer.

19 APRIL 1991

POSITIONS OPEN

FACULTY POSITIONSIN MOLECULAR REGULATIONOF CELLULAR SIGNALING

The Department of Pharmacology at the Duke Uni-versity Medical Center is increasing its faculty as a part ofa major expansion in the basic sciences. The departmentwishes to enhance its focus on molecular regulation ofcellular signaling. Applicants are being sought who havea research background utilizing modern molecular bio-logical and/or genetic technology and are interested inworking in a collegial and interactive environment. Mostappointments will be at the level ofASSISTANT PRO-FESSOR. Please send curriculum vitae, list of threereferences, and a brief description of proposed researchto: Dr. AnthonyR Means, Chairman, DepartmentofPharmacology, Box 3813, Duke University MedicalCenter, Durham, NC 27710. Duke University is an

Equal Opportunity/Affirmative Action Employer.

POSITIONS OPEN

POSTDOCTORAL POSMTIONS AT CORNELL

Available now to work on (i) novel technology for theHuman Genome Project and molecular biology of re-combination (two positions), and (ii) regulation ofHLAgene expression (one position). Prior experience in mo-lecular biology required. Send curriculum vitae to: Dr.Basil Rigas, Cornell University Medical CollegeF-231, 1300 York Avenue, New York, NY 10021.

POSTDOCTORAL POSMON. Available imme-diately at the University of California, San Francisco, tostudy molecular mechanisms underlying the regulation ofgene expression by ethanol in neural cells. Send curricu-lum vitae and names of references to: Dr. Michael Miles,Gallo Center, Building 1, Room 101, San FranciscoGeneral Hospital, San Francisco, CA 94110. TheUniversity of Calfornia is an Affirmative Action/EqualOpportunity Employer.

L-L-7Hahnemann University

DEAN OF THE GRADUATE SCHOOLAND VICE PRESIDENT FOR RESEARCH

Hahnemann University invites nominations and applicationsfor the position ofDean ofthe GraduateSchool and Vice Presidentfor Research.

THE UNIVERSITYHahnemann University is a modern, progressive health sciences institution located indynamic, center city Philadelphia. Hahnemann is comprised of the School of Medicine, theGraduate School, the School of Health Sciences and Humanities, and Hahnemann Hospital, a616-bed tertiary care center. Approximately 2,000 students are matriculated in the threeschools of the university, with over 500 candidates for advanced degrees enrolled in theGraduate School. The Graduate School offers advanced degrees in 20 basic science andclinical programs, with doctoral degrees awarded in 12 distinct areas. The Graduate SchoolFaculty currently number more than 225 individuals, and sponsored research funding for theinstitution has recently progressed beyond $14 million.

THE POSITIONThe Dean of the Graduate School and Vice President for Research serves the University indual capacities. As Dean of the Graduate School he/she reports to the Senior Vice Presidentand Chief Academic Officer and is expected to contribute dynamic leadership in fosteringexcellence in graduate education as well as facilitating the recruitment of outstandingfaculty and students. The Dean of the Graduate School is also expected to provide centralleadership in the administration of Graduate School programs and planning as well asarticulating and facilitating relationships between the Graduate School and the other twoschools of the University. As Vice President for Research, this individual serves in a staffcapacity to the Senior Vice President and Chief Academic Officer. It is anticipated that theVice President for Research will function in a leadership and advisory capacity to the ChiefAcademic Officer regarding all aspects of research, coordinating efforts within theUniversity, as well as between the University and external organizations both public andprivate. In both capacities of the position, it is expected that this individual will function inintegrative relationships with others in leadership positions throughout the HahnemannHospital and University.

QUALIFICATIONSCandidates should present with a distinguished record of academic leadership experience,preferably at the graduate level, and a demonstrated ability to function effectively withfaculty, students, alumni and other central administrators in the University. An equivalentexperience in industry would also qualify the candidate. Each candidate shoulddemonstrate extensive administrative experience in graduate education and research,characterized by a scope and level of fiscal complexity consistent with the requisites of thecurrent position. An earned doctorate in an appropriate area of science or medicine isrequired, as is a consistent record of accomplishment in sponsored research funding. Inaddition, a proven record of success in relating to government and private funding agencies,leadership experience in large collaborative interdisciplinary research programs andproficiency in interpersonal communication and public relations skills are highly desirable.The candidate must also be capable of achieving appointment as a tenured full professor inone of the academic departments at the University.

APPLICATION OR NOMINATIONAppointment of the new Dean and Vice President will take place on or about July 1, 1991.Applications should consist of a letter of interest, a curriculum vitae, and the names,addresses and telephone numbers of three to five professional references. Letters ofapplication or nomination should be forwarded as soon as possible to:

Dr. Leonard R. DerogatisChair, Search Committee for Graduate Dean & Vice President

HAHNEMANN UNIVERSITYBroad & Vine Street

Philadelphia, PA 19102-1192Fax Number 215-448-7301

Hahnemann University is an Equal Opportunity. Affirmative Action Employer andinvites and encourages applications from women and minorities.

c r.

POSITIONS OPEN

The Department ofEcology and Evolutionary Biologyat Rice University seeks to fill a staff oition as LABO-RATORY COORDINATOR to develop and imple-ment introductory and advanced laboratories for under-graduate courses in ecology, behavior, evolution, andorganismal biology. Experience with educational com-puting, inclu network management, is especiallysought. Advanced degree required. Interested applicantsshould send a resume and three letters of reference to: J.M. Smith, Employment Office, Rice University P.OBox 2666, Houston, TX 77252 by 15 May 1991. Riceis an Equal Opportunity/Affirmative Action Employer,M/F/V/H.

PLANT PHYSIOLOGICAL ECOLOGY. Oneyear, sabbatical replacement position at Idaho StateUniversity. Teaching responsibilities include undergrad-uate physiological ecology and graduate environmentalphysiology (both team-taught), plant ecology, and gen-eral ecology. Send risume, letter that addresses prepara-tion for teaching responsibilities, and names of threereferences to: Dr. Rod Seeley, Chair, Department ofBiological Sciences, Idaho State University, Poca-tello, ID 83209. Application materials should be re-ceived by 13 May 191 but position will remain openuntil filled. Equal Opporunity/Alnmnaie Action Employer.

POSTDOCTORAL POSITION

POSTDOCTORAL POSmON. Available startingJuly 1991 to join a group to study mechanisms ofmicrovascular regulation, endothelial cell function invivo with special emphasis on eicosanoids, EDRF, oxy-gen metabolites, and cyclic GMP. Background in micro-circulatory techniques and vascular smooth muscle workpreferred. Minimum duration 2 years. Individuals withprevious postdoctoral experience are encouraged to ap-ply. Salary competitive. Applicants should send curricu-lum vitae, reprints if any, and names of three referencesto: Gabor Kaley, Ph.D., Professor and Chairman,Physiology Department, New York Medical College,Vah NY 10595. Telephone: 914-993-4089.Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL POSITION. Available imme-diately to study expression and function of Drosophilaneural peptides. Several Drosophila neural peptides froman important neural peptide family present in bothvertebrates and invertebrates have been identified. Re-search projects will involve study of the expression andfunction of these peptides utilizing biochemistry, genet-ics, and molecularbiology techniques. Candidates shouldhave a Ph.D. with ramini in biochemistry, Drosophilagenetics, or molecular biology. Please send curriculumvitae and names of three references to: Dr. R. Nichols,University of Michigan, 1121 Natural Science Build-ing, Ann Arbor, MI 48109-1048. Telephone: 313-764-4467. FAX: 313-747-0884.

DEVELOPMENTAL NEUROBIOLOGYTwo POSTDOCTORAL POSITIONS are available

to study cellular and molecular mechanisms of neuronaldifferentiation in mammalian sensory systems. Projectsinclude investigations of (i) sensory transmitter plasticity,(ii) regulation of growth factor responses, and (iii)neuron-target interactions using tissue culture, biochem-ical, molecular, and immunocytochemical methods. CaseWestern Reserve University has a large and highly inter-active Department of Neuroscience with particular ex-

rtise in cellular, developmental, and molecular neuro-biology. Funding for these positions is above theNational Institutes of Health stipend level. Please sendresume and names of three references to: Dr. David M.Katz, Department of Neuroscience, Case WesternReserve University School ofMedicne, 2119 Abing-ton Road, Cleveland, OH 44106.

POSTDOCTORAL POSITION. Research in hu-man genetics, involving new fluorescence probe technol-ogies for gene mapping and investigation of geneticdisease and chromatin organization. Experience and/orcommitment to human genetics preferr. Opportunitiesfor independent and collaborative research, availableimmediately. See Science 249, 928 (1990); Cell 57, 493(1989). Send curriculum vitae with three references to:Dr. Jeanne B. Lawrence, Department ofCell Biology,University of Massachusetts Medical School, 55 LakeAvenue North, Worcester, MA 01655.

POSITIONS OPEN

POSTDOCTORAL POSITION. Available summer1991 for investigation of cellular/molecular mechanismsof neurodegenerative diseases. Laboratory utilizes aninterdisciplinary approach to study degenerative diseaseassociated with chronic alcohol abuse and aging. Theposition is within a program of research in several areasincluding cholinergic/amino acid neuropharmacology,synaptic plasticity, and trophic factors. Curriculum vitaeand two letters of recommendation should be sent to:Bruce E. Hunter, Ph.D., Department of Neuro-science, JHMHC Box J-244, University of Florida,Gainesville, FL 32610. An Equal Opportunity/Affirna-tive Action Employer.

POSTDOCTORAL POSITION. Available imme-diately to study pathophysiologic mechanisms in immu-nologic recurrent pregnancy loss and thrombosis. Expe-rience with cell culture, immunoassays, hybridomatechnology, and/or prostaglandin chemistry desirable.Salary is $21,000 to $23,000 for the first year. Evalua-tion will begin 15 May 1991 and continue until acandidate is selected. Send curriculum vitae and threeletters of reference to: Dr. Neal S. Rote, DepartmentofMicrobiology and Immunology, Wright State Uni-versity, Dayton, OH 45435. Affirmative Action/EqualOpportunity Employer.

POSTDOCTORAL POSITIONA postdoctoral position is available for an M.D. or

Ph.D. with a strong background in molecular biologyand immunology to study the inmunogenctics of insu-lin-dependent diabetes. Research will focus on the mo-lecular biology of 1 cell autoantigens and the abnormalimmunoreactivity restricted by HLA-associated mole-cules. Send curriculum vitae with names of three refer-ences by 31 May 1991 to: Dr. Ake Lernmark, Depart-ment of Medicine, RG-20, University ofWashington,Seattle, WA 98195. FAX: 206-543-3169.

Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL POSITION INMOLECULAR/CELLULAR BIOLOGY

A position is available immediately to study the mo-lecular biology of proteins involved in the transfer oflipids among plasma lipoproteins. Research in progressfocuses on regulation of expression of the gene encodingcholesterol ester transfer protein in a variety of cell types.Experience in molecular biology is necessary. Pleaseforward your curriculum vitae and two letters of recom-mendation to: Samir Deeb, Ph.D., Division ofMedicalGenetics, RG-25, University ofWashington, Seattle,WA 98195.

An Equal Opportunity Employer.

POSTDOCIORAL POSITION. Argonne Nation-al Laboratory has an opening for a fisheries biologist/aquatic ecologist. The successful candidate, working withan interdisciplinary team, will be responsible for investi-gating the effects of daily dam operations on the nativefishes, benthos, plankton, aquatic habitats, and waterquality of the upper Colorado River. Qualifications are aPh.D. in fisheries biology or aquatic ecology, withexperience in assessing habitat requirements (indudinginstrearn flow requirements) of fish. Experience withHSI, HEP, and IFIM preferred. Please submit curricu-lum vitae, the names and addresses of three references,and a personal statement of qualifications and researchinterests by 15 May 1991, to: Susan Walker, BoxJ-EIID-Postdoc-55, Employment and Placement, Ar-gonne National Laboratory, 9700 South Cass Ave-nue, Argonne, IL 60439. An Equal Opportunity/Affir-mativ~e Action Employer.

POSTDOCTORAL POSITIONA postdoctoral position is immediately available to

study the molecular biology of Chlamydia trachomatis.Relevant experience in recombinant DNA, immunology,and pathology is desired. Send curriculum vitae andnames and addre of three references to: Luis M. de laMaza, M.D., Ph.D., Professor, Department ofPathol-ogy, Medical Sciences I, University of California,Irvine, CA 92717. An Equal Opportunity Employer.

SCIENCE welcomes placement of line classified adsby FAX. Please include name and telephone number forour confirmation call when transm~iitting ad to:

FAX NUMBER: 202-682-0816SCIENCE, VOL. 252

POSTDOCTORALFELLOWSHIP

GASTROINTESTINALPHARMACOLOGY

MARION MERRELL1DOW INC.KANSAS CITY, MO

Marion Merrell Dow Inc. is seekingapplications forapostdoctoral fellow-ship In gastrointestinal pharma-cology to be located at its KansasCity MO site. The area of researchwill focus on aspects of intestinalelectrolyte transport and its regula-tion. Key projects will stress: 1) therole ofreceptors. second messengersand ion channels in transport and.2) inter-disciplinary collaborationswith other departments with thecompany. Applicants must possessa Ph.D. degree in pharmacology,physiology, or biochemistry with anemphasis on intestinal transport.This 2-year fellowship is supportedby a competitive salary and benefitspackage.Qualified applicants are asked tosend a current CV including a list ofpublications, the names. addresses.and phone numbers of three refer-ences. and a short statement ofcareer goals to:

Dept JFNP

MARION MERRELL DOW INC.

P.O. Box 9627Kansas City, MO 64134Equal Opportunity Employer

|ASSOCIATElSCIENTISTlPOSITIONPosition available for AssociateScientist (three years post-doctoralexperience) and/or postdoctoral fel-low. The successful applicant will beengaged in research on the bio-chemical and molecular mechan-isms by which angiotensin peptidesand other hormonal and pharmaco-logical stimuli mediate cardiac mus-cle cell growth. There will also be theopportunity to engage in researchdefining the role of a localizedintracardiac renin-angiotensin sys-tem in mediating cardiac muscle cellgrowth, with an emphasis on theregulation of the precursor genes forthis system.Competitive salary and fringebenefits are available. Please sendCV and three names or letters ofreference to: Dr. Kenneth M. Baker,Wels Center for Research,Gelsinger Clinic, North AcademyAvenue, Danville, PA 17822-2611.Equal opportunity employer M/F/HN.GeisinSer

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ResearchAssociateLmmunobiology

Genentech, a leader in the biotechnologyindustry, is seeking a Research Associate forour Immunobiology departmentWithin this department, you will join some ofour exciting research to develop therapeu-tics for human disease.A strong backgroundin molecular biology including at least 3years' research experience is required.Experience in cell culture and receptorbinding is desirable.Our progressive company offers an excep-tional compensation and benefits packageand the opportunity to make a significantcontribution to our organization. Forimmediate consideration, please send yourresume to Genentech, Inc., Human Re-sources Dept. YSAA, 460 Point San BrunoBlvd., South San Francisco, CA 94080. Weactively support and promote affirmativeaction and equal opportunity employment

Genentech, Inc.

AilMEFORACHILEVEENTThe opening ofGlaro Inc.'s $350million Girolami ResearchCenter in Research TrianglePark, NCrepresents ourcontinuedcommitment in thepharmaceuticalindustry to the discovery ofdrugsfor unmet patient needs.Scientists engaged in Glaxo'sexpanding research anddevelopment programs at theCenter have a premierfacility inwhich to work. Thefollowingopportunity is now available:

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We are seeking a Receptor Biochemist toestablish a laboratoryfocusing on cellularregulation via the modulation ofintracellularhormone receptor activity. The laboratory willfunction as one unit ofinterdisciplinary teamsin the therapeutic areas ofcancer andmetabolic diseases.

The successful candidate should have a Ph. D.in Biochemistry or related area ofstudy with atleast two years ofpostdoctoral experience. Astrong background in in vitro receptorbiochemistry and an interest in related therapeuticareas is required, as is the ability to establishfruitful collaborations with other laboratorieswith similar therapeutic targets.

Oar Research Triangle Park, NC location (nearRaleigh, Durham and Chapel Hill) is unequalledforpeople who seeka well-rounded lifestyle. Thisworld-famous scientific, industrial, andacademiccommunity affords access to respecteduniversities, beautiful residential areas, majorretail centers, excellent health care andabundantcultural and recreationalfacilities. Join Glaxoand enjoy an excellent salary, flexible benefits,an on-site recreation andfitness center, a spiritofenthusiasm and teamwork and outstandingopportunitiesfor career satisfaction.

Send your resume, including salary history, to:Human Resours Department, Job#9126B142-SC, Glaxo Inc., PO. Box 13398;Research Triangle Park, NC 277J9. (NoPhone Calls or Agency Referrals, Please.) AnEqual Opportunity Employer M/F/H/V

Glaxo Inc~

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FROMSCIENCE

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MasterCard and VISA.

Please let us know on your ad order thatyou wish to take advantage of this

service, or ask us for further details.SCIENCE Classified Advertising

Tel: 202-326-6555 FAX: 202-682-0816

UNIVERSITY OF HAWAII AT MANOA

DEAN, COLLEGE OF NATURAL SCIENCESThe University of Hawaii at Manoa invites nominations and applications for the position of Dean of the College of Natural

Sciences. The individual chosen must be a dynamic leader with a strong commitment to excellence in teaching, research and

service and have a vision of the College's future that is compatible with Hawaii's unique attributes.

Duties: The Dean serves as chief academic and executive officer of the College and reports to the University of Hawaii Senior

Vice President for Academic Affairs. The College of Natural Sciences is one of four colleges in the Colleges of Arts and

Sciences, and consists of 150 faculty members in eight departments (Botany, Chemistry, General Science, Information and

Computer Sciences, Mathematics, Microbiology, Physics and Astronomy, and Zoology), one program (Biology) and two

interdisciplinary graduate specializations (Ecology, Evolution and Conservation Biology, and Marine Biology). The Dean

oversees an annual budget in excess of $10 million.

Minimum Qualifications: Qualified candidates must have an earned doctorate in the natural sciences or a related

discipline; satisfy the College's and University's requirements for tenure as a full professor; possess significant professional

teaching and research experience; have a substantial national reputation as a scientist, educator and/or administrator; have

knowledge of higher education instructional and research policies and issues; and have three years academic or scientific

administrative experience.Desirable Qualifications: Candidates should be committed to the ideals of a liberal university education and to

excellence in science education; have knowledge of higher education trends, issues and developments in both undergraduate

and graduate education; be able to operate within a university setting exhibiting competence in fiscal and personnel matters;

have experience as a dean, associate dean or equivalent position in a program of comparable size and diversity; exert positive

leadership for faculty, students and the larger professional community in an environment of consultation and delegation of

responsibility; have the capability to generate, communicate and implement a clear vision of science education and research for

the University and State; understand the complexities and requirements of education and practice in a multi-cultural context; be

able to interpret the College's mission and achievements within and outside of the University; and have demonstrated leadership

in the acquisition and management of substantial budgets and private and governmental funding as well as have extensive

knowledge of the needs of the various natural sciences represented in the College.

Starting Date: Preferred, January 1, 1992 or as soon thereafter as possible.

Salary: Commensurate with qualifications.Applications and Nominations: The committee plans to begin reviewing applications on August 1, 1991, and

anticipates inviting candidates to the campus in early Fall 1991. Applicants should send a letter of application, current

curriculum vitae, names, addresses and telephone numbers of three professional references, and a concise statement of how

they meet the minimum and desirable qualifications. Applications should be sent to: Dr. Madeleine J. Goodman, Assistant Vice

President for Academic Affairs, University of Hawaii at Manoa, 2444 Dole Street, Bachman 105, Honolulu, Hawaii 96822.

Inquiries concerning this position should be communicated to Dean David Greenfield, Chair, Natural Sciences Dean Search

Committee, (808) 956-7541.

The University of Hawaii at Manoa is an Affirmative Action, Equal Employment Opportunity Employer. Women, minority, and

disabled candidates are encouraged to apply.

FACULTY POSITONSThe Salk Institute invites appli-

cations for faculty positions toexpand its Program in HumanGenetics. While applications rele-vant to all areas ofmoleculargenetics will be considered, we are

especially interested in individualswho will apply contemporarygenetic approaches to study funda-mental biological questions relatedto human heritable diseases orcancer. The Salk Institute hasstrong and interactive programs inCancer Molecular Biology,Neurobiology, Growth Regulation,Gene Expression andNeuroendocrinology.

Candidates should send a C.V.,briefsummary of future researchplans and arrange for three lettersof reference to be sent to: Dr.GeoffWah, Human GeneticsSearch Committee, The SalkInstitute, 10010 N. TorreyPines Rd., La Jolia, CA 92037.

SALK INSTTUTEEqual Opportunity Employer M/FN/H

STAFF!RESEARCHBIOCHEMIST

The Biochemical and Molecular

Pathology Department at Merck Sharp& Dohme Research Laboratories is

seeking an experienced biochemist

with a strong enzymology background.Knowledge of UNIX and DOS with an

interest in automation and robotics is

desirable. This individual will be

responsible for developing and

implementing high capacity enzymeassays seeking novel agents from

natural product sources. This personmust be analytical, highly organizedand possess good communication

skills. The candidate must have a

BS/MS or equivalent in Biochemistry.

Merck Sharp & Dohme Laboratories is

located in Rahway, New Jersey,approximately 25 miles form New York

City. Our salaries, benefits and growthpotential are excellent. For con-

sideration, send your resume and the

names of three references to: Human

Resources Manager (R80-A3),Attn: Ad #72, P.O. Box 2000,

Rahway, NJ 07065.

An equal opporturitylaffirmative action employer.

THE INTERNATIONAL RICE RESEARCH INSTITUTEPosition Announcement

forPROGRAM LEADER, RAINFED LOWLAND RICE PROGRAM

The International Rice Research Institute (IRRI), a member of the Consultative Group on InternationalAgricultural Research (CGIAR), is a nonprofit autonomous organization engaged in research and training in rice-related technology. Its goal is to enhance rice production and sustainability to benefit the world's 1.3 billion peoplewho are dependent on rice for their livelihood and as their basic food. IRRI seeks a Program Leader for its RainfedLowland Rice Program who will work with interdisciplinary teams of scientists from the biological, physical, andsocial sciences.

* Conduct and lead research on major production issues of Rainfed Lowland Rice.* Provide leadership to the overall planning and administration of IRRI's Rainfed Lowland Rice Program.* Participate actively in the implementation of IRRI's Five Year Work Plan and identify new research priorities.* Support project coordinators, and determine with them the human, financial, and physical resources needed

to implement research projects, and ensure program balance.* Monitor, review, and evaluate research and project budgets and take corrective action when necessary.* Coordinate program reporting through annual reports, reviews, and other mechanisms.* Provide dynamic leadership at key sites and within the research consortium for rainfed lowland rice in

collaboration with national programs.QufluwAwon

* PhD in biological sciences, preferably in agronomy.* Experience in coordination and management of science (vision and leadership capability).* Experience in rice, particularly in Asia, is highly desirable.* Excellent ability to speak and write in English.* Proven scientific capability as evidenced by publication record and other scientific contributions.

Salary and perquisites will be commensurate with those of similar international institutions and progams inagriculture. The person chosen for the position will live at IRRI Headquarters on the campus of the University of thePhilippines at Los Banos, 60 km south of Manila.

- IApplications with full documentation, including three referees (or the names of nominees) should be addressed

to Dr. Klaus J. Lampe, Director General, IRRI, P.O. Box 933, 1099 Manila, Philippines. Telephone (63) 2-818-1928;FAX: (63) 2-818-2087.Dealne

Applications should be received not later than 15 May 1991. Interviews of short listed applicants will commenceas soon as possible.

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CHAIRPERSON

Department ofHuman GeneticsAllegheny-Singer Research Institute (ASRI) is seeking a qualified individual for the position of Chairpersonof the Department of Human Genetics. ASRI is part of the Allegheny System-a major academic healthsystem-which includes Allegheny Health Services (the non-profit parent corporation), Allegheny GeneralHospital (AGH), The Medical College of Pennsylvania (MCP), Allegheny Neuropsychiatric Institute (ANI),and Allegheny Health Foundation (AHF).Responsibilities of the position include the establishment and direction of a Department ofHuman Geneticscapable of achieving national prominence; fostering and overseeing the development of clinically relevant,independent and collaborative interdisciplinary research projects capable of competing for peer-reviewed,extramural funding; attracting a critical mass of productive researchers for the department; and the develop-ment of strategies to carry out the long-term mission to advance the clinical capabilities ofAGH through earlyclinical application of research findings.Eligible applicants should have a doctoral orequivalent degree and demonstrated accomplishments to qualifyas a full professor at the Medical College of Pennsylvania, a minimum of five years of experience either direct-

ing or assisting with the direction of significant research in genetics, and demonstrated research credentials.

Interested candidates should apply by submitting a curriculum vitae to Dr. Leonard L. Ross, AnnenbergDean, The Medical College ofPennsylvania, cdo Allegheny Campus, 320 East North Avenue, Pittsburgh,PA 15212. An Equal Opportunity Employer.

55L'LWI2JR41BI9IThe King Faisal Specialist Hospital and Research Centre in Riyadh, Saudi Arabia has the following positions available.

RESEARCH PROGRAMMER/ANALYST-BS degree in a scientific discipline and experience working with biologists orclinicians in a computing capacity. Knowledge of Fortran and C and experience with PCs, VAXes or UNIX work stations.

BIOMEDICAL STATISTICIAN-PhD in Biostatistics or related scientific field, five years post PhD experience. Knowledgeof biological image analysis or mathematical modeling of biological systems.CHIEF RESEARCH TECHNICIAN-BS degree in life sciences and seven years research experience. Must be capable ofestablishing and maintaining mammalian fibroblast, lymphoblast, short-term myoblast and neuroblast cultures.Experience in molecular biology or biochemistry or a record of participation in publications is preferred.

ASSOCIATE SCIENTIST-Post-Doctoral position in the Virology and Immunology Section. Demonstrated researchexperience in cytokine effect on the immune response during infection (herpes viruses and papilloma viruses inparticular), T and NK cell responses including cytotoxicity assays and characterizations of microbial antigens.

ASSOCIATE SCIENTIST-Post-Doctoral position with research experience in diagnosis of infectious diseases by nucleicacid probes and working experience with PCR and all molecular biology techniques. Knowledge of identification ofantimicrobial resistance genes is desired.EXECUTIVE ASSISTANT-BS degree in Hospital or Business Administration, MS degree preferred. Four years experiencein management with scientific and research exposure preferred.

Benefits indude potentially tax-free salary, liberal vacation and holidays, furnished housing and air transportation.To apply, send curriculum vitae to: HCI, 2515 Park Plaza, Nashville,TN 37203. In Europe HCI, St. Christopher'sHouse, St. Christopher's Place, London, EnglandW1M 5HD. HCI is an equal opportunity employer.

HOSPITAL CORPORATION INTERNATIONALA

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Position available immediately forqualified peptide chemist to workin the Biological ResourcesBranch, National Institute ofAllergy & Infectious Diseases,National Institutes of Health.Candidate should have expertisein synthesis, in purification andanalysis of peptides. Experi-encein protein chemistry includingcompositional and sequenceanalysis would be helpful.Laboratory management experi-ence is desirable. Plenty ofresources available. Salary will be

commensurate with credentials.

Qualified and interested candi-dates should send curr-culumvitae and names and addressesof three (3) references to:

John E. Coligan, Ph.D., ChiefBiological Resources Branch

NIAID, NIHBuilding 4, Room 4139000 Rockvllle PikeBethesda, MD 20892

(301) 496-3213

NIH is an Equal Opportunity Employer

UNIVERSITY OF LONDON

UCL NIVERSITY COLLEGE LONDONCUAR OF MOLECULAR BIOLOGY

The Colge is seeking to appoint to this newChair a scientist of international standingwith an active research programme in theMolecular Bblogy of eukaryotic cells, prefer-ably with interests in the products and conse-quences of gene expression (rather thangene regulation), to pon a Medical Research,Council (MRC) Laboratory InterdisciplinaryResearch Centre (IRC) in Molecular CellBiolgy) currently being established on theGower Street campus at UCL. The IRC build-ing will have excellent research facilities andwill house 10-12 oher research teams. It willhave its own graduate student and seniorfelbwship programmes. The person appoint-ed will play a eading role in developing theseprogrammes and will also be able to developresearch and other academic interactionswithin UCL.

Applications (11 copies: 1 from overseasapplicants) should be sent to The Provost,University College London. Gower Street,London WC1E 6BT by 17 May 1991. Furtherdetails may be obtained from the DeputyRegistrar. Persons interested in the post are

encouraged to make informal contact withProfessor C. Hopkins. Director of the IRC(Tel: 071-823 9137 or 225 8265; FAX 071-581 0865), Professor M Raft (Tel: 071- 3807016) or Professor D. Brown (Tel: 071-3877050 ext. 3751).

Equal Opportunities Employer.

POSITIONS OPEN

POSTDOCTORAL POSITIONPROTEIN ENGINEERING

Abbott Laboratories currently has a position availablein our Corporate Molecular Biology Department. Thecandidate will develop methods to design, construct, andanalyze novel peptides and proteins. The selected indi-vidual will apply modern techniques in gene cloning andmutagenesis, protein modeling, and selection methodsemploying filamentous phage. A Ph.D. or equivalent inbiology or chemistry, laboratory experience in genecloning, and previous participation in a protein struc-ture-fimction project are required. This assgnment willbe for 2 For consideration, please sen resume to:Ann Ri , Corporate Placement, Job #36071,Abbott Laborao , One Abbott Park Road, AbbottPark, IL 60064.Abbot is anAlnnativ Acion Employer.

ABBOIT LABORATORIES

STAFF FELLOWSHIP. In the Malaria Section ofthe Laboratory of Parasitic Diseases, National InstituteofAllergy and Infectious Diseases, National Institutes ofHealth (NIH), Public Health Service. The applicant willwork on a program related to identifying recombinantproteins that will lead to protective immunity. Theapplicant should have a Ph.D. with experience docu-mented with publications in cellular immunology andmolecular biol~ogy of the malaria parasite. Salary range:$24,000 to $36,000, depending on postdoctoral experi-ence. Send curriculum vitae to: Louis H. Miller, Head,Malria Section, Building 4, Room 126, NIH, Be-thesda, MD 20892. FAX: 301402-0079.The NIH is an Equal Opportunity/Affirmative Action

Employer.

POSTDOCTORAL POSMONTHE ROCELLER UNIVERSITY

A postdoctoral position is available to study the bio-synthesis of glycosyl-phosphatidylinositol membrane an-chors of eukaryotic cell-surface proteins. Projects revolvearound the biochemical steps involved in the construc-tion of the glycolipid and its transfer to protein, andgenetic and biochemical approaches to studying enzymesinvolved in anchor biosynthesis in trypanosomes, yeast,and mammalian cells [see J. Biol. Chem. 265, 9033(1990); EMBOJ. 9,4249 (1990)]. Previous experiencewith biochemistry and/or molecular biology is preferred,but not essential. Send curriculum vitae and names oftwo referees to: Dr. Anant KL Menon, Laboratory ofMolecular Parasitology, The Rock ler University,1230 York Avenue, New York, NY 10021. TheRockefiller University is an Equal Opportunity/AffrnativeAction Employer.

CLINICAL CHEMISTRY FELLOWSHIPS atMayo Clinic. Seeking applicants for 1- or 2-year fellow-ships in training programs directed toward qualifiedindividuals (Ph.D. or M.D. required) pursuing careers inclinical chemistry. Individuals completing the programare eligible for certification by the American Board ofClinical Chemistry or for subspecialty certification by theAmerican Board of Pathology. Aplications on fife byJuly (pathology) or October (postdoctoral) 1991 will beconsidered for appointment m July of 1992. Contact:Mary F. Burritt, Ph.D., Division of Laboratory Med-icne, Mayo Clinic, Rochester, MN 55905, for moreinformation. Mayo Foundation is an ffirmative Action/Equal Opportunity Educator and Employer.

POSTDOCTORAL FELLOWSHIPNATIONAL INSTITUTES OF HEALTH (NIH)

Vacancy for a postdoctoral fellowship in the Labora-

tory of Molecular Growth Regulation, NICHD, NIH.

The successful candidate will be expected to conduct

research on the role of RNA polymerase Ill-transcribed

interspersed repetitive sequences in control of mammali-an cel growth and differentiation. Applicants must pos-sess an M.D. or Ph.D. de or equivalent experienceand have experience in techniques of molecular doning,analysis of gene expression, protein purification, and

mammalian gene transfer. Salary range: $25,000 to

$38,000. Send curriculum vitae, statement of research

experience, and three letters of recommendation to: Dr.

Bruce H. Howard, labaor of Molecular Growth

Regubdot National Institutes of Health, Building

6,¶ 416, 9000 Rockvile Pike, M1B20892 by 10 May 1991. NIH is an Equal OpportunityEmployer.

POSITIONS OPEN

POSTDOCTORAL POSMON. Available 1 July1991 in research related to human autoimmune diseasesat the Harvard Medical School and the Center forNeurologic Diseases ofBrigham and Women's Hospital.The position requires interest and/or expertise in humanT cell immunology including T cell interactions andregulation by cytokines including TGF-beta. The posi-tion involves characterization of immunoregulatory Tcell abnormalities in multiple sclerosis and other autoim-mune diseases and investigation of mechanisms of in-munologic tolerance in humans. Send curriculum vitaeplus names and telephone numbers ofthree references to:Dr. Howard L. Weiner, Co-Director, Center forNeurologic Dises, Brigham and Women's Hospi-tal, 75 Francis Street, Boston, MA 02115.

POSTDOCTORAL POSMON. At Oak RidgeNational Laboratory (ORNL) to do research on ultra-sensitive detection techniques as applied to DNA se-quencing problems. Degree in analytical/physical chem-istry or applied physics with background in opticalspectroscopy preferred; should have experience withlasers and optics and background in instrumentation. Forposition information, contact: J. Michael Ramsey,ORNL, P.O. Box 2008, Oak Ridge, TN 37831-6142. For application material, contact: PostgraduateResearch Propaam/Genome, Science/Engineering Ed-ucation Division, Oak Ridge Associated Universities,P.O. Box 117, Oak Ridge, TN 37831-0117. Tele-phone: 615-576-3456.

POSTDOCTORAL FELLOWSHIP. Position inmolecular and cellular biology. A position is availableimmediately to identify and isolate the intracellular pro-tein targets of oncogenic ras p21 protein. Candidatesshould have the Ph.D. degree with experience in molec-ular biology and protein biochemistry. Send curriculumvitae and three references to: Dr. Matthew R Pincus,Departments of Biochemistry and Pathology, SUNYHealth Science Center, 750 East Adams Street, Syr-acuse, NY 13210. Telephone: 315-464-6785 or Dr.Paul Brandt-Raut, Comprehensive Cancer Center,Columbia University, 60 Haven Avenue, New York,NY 10032. Telephone: 212-305-3464.

THE MORRISON MEMORIALPOSTDOCTORAL FELLOWSHIP

The Department of Biochemistry, St. Jude Children'sResearch Hospital (SJCRH), is enlarging its researchefforts in the area ofthe molecular and cellular biology ofsignal transduction. As part of this expansion, the Boardof Governors has established a memorial fellowship inhonor ofDr. Martin Morrison, the founding chairman ofthe department. The research programs with the depart-ment are well equipped and offer recent Ph.D. or M.D.graduates the opportunity to participate in energeticmultidisciplinary groups dealing with a range of basicand clinically oriented research. SJCRH offers a compet-itive stipend and annual review for reappointment. Thebeginning date of the fellowshi is July 1991. Currentrearch programs within the epartment include:* W. Y. Cheung: Regulato2r properties and biologi-

cal functions ofcalmodulin, Ca +-regulated enzymes andother Ca2+-binding proteins.* J. Cleveland: Transcriptional regulatory factors

which control myeloid cell cycle progression.* J. N. Ihile: Mechanisms of hematopoietic stem cell

growth regulation, differentiation and transformation.* S. Jackowsk: Cell cycle regulation of membrane

phospholipid biosynthesis.* C. Rock: Role ofphospholipid-derived second mes-

sengers in growth factor action.Applicants should submit a brief statement of their

research interests, curriculum vitae, reprints, and thenames of three references to:

The Morrison Postdoctoral FellowshipDepartment of Biochemistry

St. Jude Children's Research Hospital332 North LauderdaleMemphis, TN 38101

An Equal Opportunity/A llrmative Action Employer.

[ SCIENCE recruitment ads reach thousands

of scientists in all disciplines, worldwide.

Clasified Advertisng telephone: 202-326-

6555. FAX: 202-682-0816.

SCIENCE, VOL. 252

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POSITIONS OPEN

POSTDOCTORAL PHARMACOLOGIST. Towork on ac-adrenergic receptor subtypes, second mes-sengers, and effects of psychoactive drugs in cell cultures.Contact: Dr. Kenneth Minneman, Department ofPharmacology, Emory University School of Medi-cine, Atlanta, GA 30322 by 31 May 1991. EmoryUniversity is an Equal Opportunity Employer.

POSTDOCTORAL POSITION. Two to threeyears available immediately in a laboratory that is cloningand expressing genes for the NMDA receptor frommammalian brain. Salary: $22,000 to $25,000. Area ofstudy includes gene doning, DNA sequencing, geneexpression, protein purification, and ion channel mea-surements. Experience in molecular biology required.Deadline for applications: 6 May 1991. Send curriculumvitae and names, addresses, and telephone numbers ofthree references to: Dr. Elias K. Michaclis, Universityof Kansas, Center for Biomedical Research, 2099Constant Avenue, Lawrence, KS 66047. Equal Oppor-tunity/Afflrmative Action Employer.

Asagdcfrd United States

POSTDOCTORAL RESEARCH ASSOCIATE.Immediately available to characterize proteins of thenewly discovered protozoan parasite, Neospora caninum.Candidate must have a Ph.D. in immunology or molec-ular biology. Salary is commensurate with experience($31,116 to $37,294). Send applications (SF-171) to:Dr. J. P. Dubey, USDA, ARS, Zoonotic DiseasesLaboratory, Building 1040, BARC-East, 10300 Bal-timore Avenue, Bdtsville, MD 20705-2350. Applica-tions should be marked 2E003 and received by 1 July1991.An Equal Opportunity Employer. Women and minor-ities are encouraged to apply.

POSTDOCTORAL RESEARCH FELLOW-SHIP. Available 1 July 1991. NIH-funded 2-year posi-tion for Ph.D. to study drug resistance and DNA toaiso-merases in leukemialcolon cancer. Biochemistrym,biology, and tissue culture background desirable. Must beU.S. citizen orpermanent resident Send curriculum vitae to:Dr. Robert Silber, New York University Medial Cen-ter (NYUMC), 550 1stAvenue, NewYork,NY 10016.NYUMC is an Equal Opportunity/Affirmtive Action Em-ployer. Applicationsfrom minorities are strongly encouraged.

RESEARCH ASSOCIATE. Ph.D., biochemistry,cell/molecular biology; intracellular processing and secre-tion of regulatory proteins in endocrine cells. Excellentfacilities. Available now. Contact: David V. Cohn,Ph.D., Health Sciences Center, University of Louis-ville, Louisville, KY 40292. Telephone: 502-588-7507; FAX: 502-588-7240. Equal Opportunity/lAffir-mative Action Employer.

POSTDOCTORAL/RESEARCH ASSOCIATEPOSITIONS. Available to study development of neuro-endocrine systems, mechanisms of action of neuropep-tides on anterior pituitary gland hormone secretion,and/or control mechanisms or reproductive hormonesecretion. Candidates should have experience in molecu-lar biology, developmental or cell biology, andlor repro-ductive physiology. Salaries are most competitive andnegotiable. Send letter, curriculum vitae, and list ofthreererences to: Charles A. Blake, Chaiman, Depart-ment of Anatomy, Cell Biology, and Neurosciences,School of Medicine, Columbia, SC 29208. An Affr-mative Action/Equal Opportunity Employer.

RESEARCH ASSOCIATE. Position available forEXPERI1ENCED ELECTRON MICROSCOPISTwith mastery of scanning and transmission electronmicroscopy; serial sectioning, morphometry, freeze frac-ture; to do low-temperature scanning, transmission,high-voltage electron and light microscopy of lung, run

laboratory. Send curriculum vitae, reprints, and samplemicrographs to: Dr. Jacob Bastacky, 1-116, LawrenceBerkeley Laboratory, University ofCalifornia, Berke-lcy, CA 94720.

BiophysicistBASF Bioresearch Corporation

The "Spirit of Innovation" thrives at BASF Corporation, aFortune 100 Company, where innovative thinking cre-ates new products, new services, and new worlds oftechnological excellence.

BASF Bioresearch Corporation, a wholly owned sub-sidiary of BASF Corporation, dedicated to becoming oneof the world's largest biomedical research facilities, andconcentrating on development of treatments for cancerand immune system disorders, has an immediate oppor-tunity available for a Biophysicist to join theBiotechnology Group at our Cambridge location.

This new position in our expanding research divisionrequires a scientist with a strong and extensive back-ground in biophysics. You will coordinate the start-up ofour Biophysics Laboratory. Your responsibilities willbegin with the automation of assay systems as well ascomputer-assisted analysis of data which includes ourDNA core facility for sequencing. You will also collabo-rate with the other scientists in setting up new equipmentin the Biophysics Laboratory. To qualify, you must havea Ph.D in Physics or Biophysics and several years ofexperience. A background in Molecular Biology ispreferred.

Share The Spirit of Innovation that has fueled the growthof BASF for over 125 years. Our compensation and ben-efits program are representative of our industry leader-ship position. For prompt consideration, please forwardresume and salary history to: Pamela S. Zupfer, HumanResources Supervisor, BASF Bioresearch Corporation,64 Sidney Street, Cambridge, MA 02139. An EqualOpportunity Employer

BAS

PERSONNEL PLACEMENT 46919 APRIL 1991

CURRENT DISTRIBUTION 160,000

(.ildXtJ GLAXO INSTITUTE FOR MOLECULAR BIOLOGY

The Geneva Molecular Biology Research Institute of one of the world's most successful healthcare groupsis offering a

POSTDOCTORAL FELLOWSHIP

The successful candidate will join a team working on the molecular basis of cell death in the vertebratenervous system. Preference will be given to candidates with experience in primary cell cultures andrecombinant DNA technology but interdisciplinary research is encouraged.

The Glaxo Institute for Molecular Biology carries out long term research to support the company-wide effortto discover effective new medicines. It provides a dynamic research environment and encourages thepublication of scientific results as well as collaborative projects with academic groups.

We offer an excellent salary and benefits package and opportunities for career development in one of themost attractive parts of Europe.

If you are interested in this position, please send your curriculum vitae with a list of publications and thenames of three referees to: Rita Gloor, Personnel Manager, GLAXO IMB S.A., 14, chemin des AuIx, CasePostale 674, 1228 Plan-les-Ouates, Geneva, Switzerland.

THE SCIENCE RECRUITMENT'FOUR-DAY CLOSE"

Now you can see your ad in SCIENCE four days after submission

Scientific recruiters can now advertise positions almost as soon as the need arises. Instead of reserving space a

month or more in advance, you can now place your ad fourdays before the magazine mailing date. SCIENCE is mailedon the cover date.

Film (right-reading, emulsion face down) or full camera-ready art and insertion order must reach: SCIENCE, ShortClose Desk, 1515 Broadway, New York, NY 10036 by NOON Mondays (except for legal holidays when material mustreach New York by NOON Fridays). Because space is limited, the four-day close page will be reserved on a first-come,first-served basis, at a 15% premium. 1/4, 1/2 or full page only.Now you don't have to wait to find the researchers you need immediately, nor must you advertise in a Sunday paper

that pans a lot of sand but not much gold. Scientific employers know that SCIENCE ads fill the job better. Now theyfill it faster too.You can call it'lNSTANT RECRUITMENT."

For further information, telephone Ed Keller, Recruitment Advertising Manager, or Gwen Cantor, Advertising TrafficManager at SCiENCE: 212-730-1050, or write to:

SdENCE 9 1515 1Broadway, NY, NY 10036

MOLECULAR GENETICSSmithKline Beecham, a world leader in pharmaceuticalresearch, has an immediate Postdoctoral Scientist opportuni-ty available in its Biopharmaceutical Research & Develop-ment organization.As a member of a research group actively studying themolecular genetics of retroviruses, the selected candidate willwork on the mechanism of action of essential retroviralproteins, in particular, the transactivator of gene expression(tat) and the retroviral aspartyl protease.Requirements for this position include a Ph.D. in MolecularBiology or other biological sciences and a strong backgroundin recombinant DNA techniques. Expression in microbialand/or eukaryotic systems as well as in gene cloning andtissue culture is highly desirable. Postdoctoral scientists arestrongly encouraged to publish research findings and toattend external scientific conferences.Our state-of-the-art research facilities are located in suburbanPhiladelphia, near Valley Forge, PA. We offer a competitivecompensation/benefits/relocation package and a stimulat-ing environment in which togrow and excel. For confidentialconsideration, send your resume and the names of threereferences to: N. Hasson, Employment Administrator,#H0168, SmithKline Beecham Pharmaceuticals, P.O. Box1539, King of Prussia, PA 19406-0939. Equal OpportunityEmployer, M/F/H/V.

SmithKitne BeechamPharmaceuticals

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SENIOR COMPUTER SCIENTISTTHE GENOME DATA BASE

andDIRECTOR

Laboratory for Applied Research in Academic Information

We seek an energetic and visionary scientist to lead an unique andinnovative program. The Laboratory for Applied Research in Aca-demic Information, a Division of the Welch Medical Library,provides leadership and comprehensive technical and educationalsystems and services support for 1) the Genome Data Base (GDB), aunique knowledge base supporting the international genome initia-tive; and 2) the Welch Library Information Systems and NetworkServices. Two additional programs are: 1) managing access to anduse of genetic and other molecular biology databases and 2) develop-ing a clinical clerkship knowledge base in collaboration with Schoolof Medicine faculty. A staff of 25 FTE supports these projects. The1991/92 budget will be approximately $2.5 million.

Requirements: An advanced degree in computer science with expe-rience in biological and life sciences, or a biological/life scientist withstrong informatics knowledge and demonstrated success with thedevelopment and management of complex knowledge bases; aminimum of five years of experience; successful research grant andcontract development and administration; and strong interpersonalskills. We wish to identify the successful candidate as soon aspossible.

This is a faculty appointment within the School of Medicine. Thelevel of appointment and salary will be commensurate with experi-ence. Mail or FAX a letter of nomination or an application withcurriculum vitae by May 1, 1991 to:

Nina W. Matheson, Director, Welch Medical Library

The Johns Hopkins University1900 E. Monument St., Baltimore, MD.

Internet: nwm@welch.jhu.eduVoice: 301-955-2702/FAX: 301-955-0985

SCIENTIST/ADMINISTRATOR FORTHE GENOME DATA BASE

We seek an energetic and visionary scientist/administrator to over-

see day-to-day administration of the Genome Data Base (GDB).Roles include program planning, policy development, negotiationswith international collaborators, and scientific support to GDB

editors.

Requirements: Advanced training in biological or life sciences, with

a strong interest in the development and management of complexgene mapping data; a minimum of five years of experience; success-

ful research grant and contract development and administration; and

strong interpersonal skills. We wish to identify the successful candi-

date as soon as possible.

This is a faculty appointment within the School of Medicine. The

level of appointment and salary will be commensurate with experi-ence. Nominations are welcome. Mail or FAX a letter of nomination

or an application with curriculum vitae by May 1, 1991 to:

Peter L. Pearson, Ph.D., Director, Genome Data Base

The Johns Hopkins University1830 E. Monument St., Baltimore, MD. 21205

Internet: pearson@welchjhu.eduVoice: 301-955-9705/FAX: 301-955-0054

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POSITIONS OPEN

; Agdcufud United StatesbiieSAC _i D ofSo~ Agok~

ARS is seeking an individual to conduct research onmolecular aspects of disease resistance and plant-microbeinteraction with emphasis on alfalfa. Incumbent will: (i)identify and done plant genes related to plant diseaseresistance and plant-microbe interactions; (ii) manipulateand transfer cloned genes into elite germplasm viaAgro-bacterium, particle gun, and related technologies; (iii)evaluate expression of introduced genes in transformedplants; and (iv) cooperate with resident plant patholo-gists, physiologists, and geneticists to develop a compre-hensive understanding of the molecular framework ofplant-microbe interactions in alfalfa. Applicants musthave a degree in genetics, plant pathology, or a relateddiscipline. Knowledge of plant-microbe interactions,molecular genetics, and plant cell biology/plant develop-ment is required. A Ph.D. is desirable. Must be a U.S.citizen. Salary commensurate with experience; range:$37,000 to $44,000. For information on the researchprogram and position, contact: Dr. Carroll P. Vance,612-625-5715. For information on application proce-dures/forms, contact: Beverly Webert, 301-344-1700.Applications in response to this advertisement should bemarked 1N028, and must be received by 28 May 1991.USDA/ARS is an Equal Opportunity Employer.

ASSOCIATE RESEARCH SCIENTIST. Researchposition available in the Department of Neurology ofColumbia University College ofPhysicians and Surgeonsfor Ph.D. interested in neurochemistry of Parkinson'sdisease and Alzheimer's disease. Applicants must have abackground in biochemistry or neurochemistry withexpeience in modemn analytic techniques applied tohuman biological fluid and tissues. Knowledge of tissueculture and monoclonal antibody techniques desirable.Preference given to individuals with evidence of researchproductivity. Send curriculum vitae and names of threereferences to: Dr. Lucien Coni, The NeurologicalInstitute, 710 West 168th Street, New York, NY10032. Columbia University is an Equal Opportunity!Affirmative Action Employer.

RESEARCH ASSOCIATE/POSTDOCTORAI4GENETICS. For research on mechanisms of mutagen-esis and the function of replication in mutagenesis.Preference for recent degree with experience in molecularbiology, enzymology, and genetics. Send curriculumvitae and three references to: T. K. Hyatt, OregonHealth Sciences University, Medical Genetics-L103,3181 S.W. Sam Jackson Park Road, Portland, OR97201-3098. Telephone: 503494-7191. An EqualOpportunity/Affirmative Action Employer.

RESEARCH ASSOCIATE

Position available to execute independent research on

the studies on genomic and cDNA libraries preparedfrom somatic cell mutants with altered membrane trans-

port characteristics. Required skills include DNA se-quence analysis, PCR, Southern and Northern blotting,loning, and gene transfer. A Ph.D. in molecular biology

is required for this position. Starting annual salary will be$26,000. Send curriculum vitae to: Georgia Depart-ment of Labor, 1275 Clarendon Avenue, AvondaleEstats, GA 30002, or the nearest Georgia Job Place-ment Center. Job Order #5475530.

RESEARCH ASSOCIATE

Design and execute independent research in theexpression and molecular analysis of normal and mutatedion transport proteins. Required skills include construc-tion of expression vectors, cell culture, gene transfer,DNA and RNA isolation, library construction andscreening, DNA cloning and sequence, Southern andNorthern analysis, in vitro transcription and translation,PCR analysis, site-directed mutagenesis, protein isola-tion and purification, chromatography, making anti-

body, Western blots, and immunofluorescence. Exe-

ence on analysis of DNA and protein with variouscomputer programs is required. A Ph.D., majoring in

molecular biology or dissertation defense is required.Starting annual salary will be $24,000. Send curriculumvitae to: Georgia Department of Labor, 1275 Claren-don Avenue, Avondale Estates, Georgia 30002, or tothe nearest Georgia Job Placement Center. Job Order# GA 5475562.

POSITIONS OPEN

UNIVERSITY OF ALBERTARESEARCH ASSOCIATE

Research associate position available for investigatingthe molecular biology of autoimmune (type I) diabetesmellitus.The applicant will be expected to have experience in

molecular biological techniques, incuding RNA andDNA isolation and analysis, cDNA preparation, PCRamplification, plasmid isolation, sequencing, cloning,vanous isotopic labeling techniques (both RNA andDNA), RNA and DNA in situ hybridization, immuno-cytochemistry, and tissue culture. Salary range is from$35,000 to $45,000. The applicant will be expected tohave a Ph.D. degree and postdoctoral experience.

In accordance with Canadian immigration requirements,priority will be given to Canadian citizens and pennanentresidents.

Applicants should send a copy oftheir curriculum vitaeand the names of two references to:

Dr. Alex Rabinovitch, Department of Medicine430 Heritage Medical Research Centre

University of AlbertaEdmonton, Alberta T6G 2S2, Canada

FAX: 403-492-3340Deadline for applications: 31 May 1991The University ofAlberta is committed to the principle of

Equity in Employment. The University encourages applica-tionsfrom aboriginal persons, disabled persons, members ofvisible minorities, and women.

RESEARCH ASSISTANT. The employee will con-duct cell culture experiments and analyze secretion prod-ucts by RIA; purify secreted products as needed byHPLC; perform Western blots of proteins in tissues andcultured cells; perform Northern blots ofmRNA for theabove proteins; quantify protein, mRNA, and lipopro-tein-cholesterol by spectrophotometric methods and se-

rum hormones and lipoproteins by RIA; and analyzedata from above and assist in manuscript preparation.Position reqires M.S. in biochemistry or physiology and1 year of laboratory research experience. Applicant mustbe certified in the handling of radioactive materials.Working hours are 8:30 a.m. to 5:30 p.m., 40 hours perweek. Salary: $22,000 per year. Send resumes to SandraStarnes, Alabama State Employment Servce, 3440Third Avenue South, Birmingham, AL 35222. Refer-ence Job Order AL0626917.

RESEARCH SCIENTIST INMOLECULAR BIOLOGY

Virginia-Maryland Regional College of VeterinaryMedicine, University of Maryland, College Park, invitesapplications for a faculty research scientist position in fishmolecular virology. Initial appointment will be in theMaryland Agricultural Experiment Station for 3 years,with likelihood of becoming tenure track. Required:Ph.D. and postdoctoral experience. Submit resume andhave three reference letters sent to: Dr. EdwardStephenson, Search Committee Chair, Regional Col-lege ofVetenary Medicine, University of-Maryland,Coliege Parkc, MD 20742. Application deadline is 15May 1991.

The University of Maryland is an Affirmative Action!Equal Opportunity Employer.

POSTDOCTORAL/RESEARCH ASSOCIATEPOSITIONS IN

BRAIN METAL PHYSIOLOGY/TOXICOLOGYAvailable immediately at the National Institute on

Aging, National Institutes of Health, Public HealthService, Bethesda, Maryland, to examine (i) metal local-ization in postmortem human brain tissue and (ii) metaltransport, distribution, and physiologic/toxicologic ac-

tions within the central and peripheral nervous systems

of small animals in aging and disease. Methods includex-ray microanalysis, atomic absorption spectrometry, in-

ductively coupled plasma-mass spectrometry (ICP-MS),and radiotracer courting. Experience in tissue sectioningand staining helpful. Positions available for up to 3 yearswith salary commensurate with qualifications. Send ap-plications with curriculum vitae and names of threereferences to: Dr. Quentin R. Smith, Laboratory ofNeurosciences, National Institute on Aging, NationalInstitutes of Health, Building 10, Room 6C-103,9000 Rockville Pike, Beda MD 20892. Tele-phone: 301496-8970. NIH is an Equal OpportunityEmployer.

472

POSITIONS OPEN

ASSOCIATE. Conduct research on neuroimmuno-logical aspects of multiple sclerosis. Job duties willinclude cell culture, animal experimentation includinginjection of cells and emulsions, immunological tech-niques including enzyme-linked immunosorbent assayand radioimmunoassay, use of radioisotopes for cell

incorporation, preparation ofmonoclonal and antibodieswith hybridoma studies and cellular proliferation withvarious mitogens. Equipment to be used will include thatfor cell culture, gamma and scintillation counting, elec-trophoresis with transfer and blotting, regular and invert-ed microscopes, enzyme-linked immunosorbent assay

reader, centrifuges, ultracentrifuges and spectrophotom-eters. Will serve as Assistant Director of the MultipleSclerosis Research Laboratory. Must have M.D. or

Ph.D. in immunology/neuroimmunology with 2 years ofexperience in multiple sclerosis research. Salary: $30,290per year; 8:00 a.m. to 5:00 p.m., 40 hours per week.Contact: Sandra T. Starnes, Alabama State Employ-ment Service, 3440 Third Avenue, South, Birming-ham, AL 35222. Job Order #AL0626913.

RESEARCH ASSISTANT PROFESSOR. To joina group investigating the molecular basis for active ion

transport across cell membranes. Applicants must havePh.D. and at least 3 years of postdoctoral experience inenzymology, protein chemistry, or molecular biology ofmembrane transport proteins. Experience using microor-ganisms for the heterologous expression of proteins isdesirable. Send curriculum vitae, brief statement of re-

search experience and career goals, and names and ad-dresses of two references by 15 May 1991 to: Dr.Robert A. Farley, Department of Physiology andBiophysics, University of Southern California Schoolof Medicine, 2025 Zonal Avenue, Los Angeles, CA90033.An Equal Opportunity/Affrnative Action Employer.

ASSISTANT RESEARCH BIOCHEMIST. TheUniversity of California, San Francisco (UCSF), issearching for a molecular biologist (Ph.D. or M.D.)beginning July 1991. Candidates should have extensiveknowledge of molecular biology and cell biology. Exper-tise to DNA cloning and sequencing, PCR, vectorconstruction, site-directed mutagenesis, eukaryotic genetransfection, and a minimum of 2 to 5 years of postdoc-toral experience are required. A background in oncorneand tumor suppressor gene molecular biology is desir-able. Send curriculum vitae and names ofthree referencesto: Dr. Young S. Kim, G1 Research Laboratory(151M2), VA Medical Center, 4150 Clement Street,San Francisco, CA 94121. UCSF is an AffirmativeAction/Equal Opportunity Employer.

ASSISTANT RESEARCHER. To conduct researchon neurophysiological mechanisms underlying the neuralcontrol of respiratory movements in mammals. Designand conduct experiments and use computer to modelexperimental data. Requirements: Ph.D. in kinesiologywith research emphasis on neural control of respiratorymovements. Demonstrated abilities in whole cell patchdamp recording, electrophysiological experiments, andcomputer modeling of experimental data. Ability todesign electronic equipment to perform aforementionedexperments. Familiarity with numerical methods andability to write real-time data acquisition and analysisprograms running on VAX computers using C, FOR-TRAN, and Decwindow programming language. Joblocation/interview: Los Angeles. Salary: $39,000 peryear. Send this ad and resume to: Job #LQ6109, P.O.Box 9560, Sacramento, CA 95823-0560 no later than6 May 1991.

POSTDOCTORALRESEARCH ASSOCIATE

Two positions available immediately for recent Ph.D.'sto study: (i) role of cell cycle genes in the regulation ofhuman megakaryocyte polyploidization and (ii) role ofprotooncogenes in regulation of normal and malignanthuman hematopoiesis. Projects rely heavily on "mi-cromethodologies" for analysis of small cell samples anduse of antisense DNA for determination of gene func-tion. Prior experience with recombinant DNA tech-niques required, tissue culture experience highly desir-able. Salary commensurate with eperience. Sendcurriculum vitae and three letters of rerence to: AlanM. Gewirtz, M.D., Room 230, John Morgan Build-ing, University of Pennsylvania School ofMedicine,36th Street and Hamilon Walkc, Philadelphia, PA19104. Equal Opportunity Employer/Affirmative Action.

SCIENCE, VOL. 252

| ~~~~~1992COMPETITIONl

FIVE FELLOWSHIPS AVAILABLEMerck Sharp & Dohme Research Laboratories, through its Academic Development Program, and the AmericanFederation for Clinical Research Foundation announce the 1992 competition for the Merck-AFCR Foundation MD-PhD Postdoctoral Fellowships to support the further training of MD-PhD scientists.

FELLOWSHIP TERMS* Candidates must have completed an MD-PhD educational program and be accepted into a postdoctoral training

program.* Candidates must provide evidence of 2 years of clinical training or have completed residency training at the time

the award begins (July 1, 1992).* Fellowships are intended for independent research in the biomedical sciences, including the fields of:

biological chemistry; cellular, molecular and structural biology; epidemiology; genetics; medical informatics;microbiology; immunology; pharmacology, physiology; pathology.

* Candidates must be citizens of the U.S. or Canada or permanent residents of the United States.* Fellowsmustdevote 80% ofhis/hertime to research. Each Fellow will spenduptothree days intheMerckResearch

Laboratories during his/her tenure as award recipient and present research results. Travel support will be providedfor the Fellow's mentor. The Fellow must maintain membership in the American Federation for Clinical Researchand must submit an abstract to and attend a Regional or National AFCR meeting each year.

* First-yearsupport consistsofa $40,000 stipend and a $3,000allowance fortravel,journal subscriptions and societymemberships. In addition, the recipient's university will receive a $7,000 grant for supplies related to the fundedresearch. Indirect costs will not be allowed.

* Fellowships may be renewable on an annual basis foran additional two years, pending approval ofannual progressreports.

FELLOWSHIP APPLICATION TERMSAll applications must be submitted on the official Merck-AFCR Foundation MD-PhD Postdoctoral Fellowshipapplication form. Each application must include:* A curriculum vitae* One page abstract of the proposed research* A proposal of 8 to 10 pages, including background and references* A statement of the applicant's career goals* Two letters of recommendation* Two reprints of published papers representative of the applicant's research* A letter from the applicant's mentor describing how- the proposed research will contribute to the applicant's

development as a creative scientist.

IMPORTANT DATESDeadline for receipt of applications - July 15, 1991. Fellowshiprecipients will be notified by December 15, 1991. Fellowships

begin July 1, 1992, unless otherwise agreed.

FOR APPLICATIONS AND INQUIRIES:Merck-AFCR Foundation Fellowship Program

AFCR Headquarters

6900 Grove RoadThorofare, NJ 08086 FoundGtlo4

Phone: 609-853-9129, Ext. 293Fax: 609-853-5991

EJ

Senior Staff Fellowshipin Psychiatry andMolecular Genetics

Opening for a researcher withexperience in clinical genetics ofmental illness, and molecular biology,to pursue genetic linkage studies inmental illness.

Requirements: M.D., BE/BC inpsychiatry, and at least fours years offellowship experience in moleculargenetics.Salary: Depends on education andexperience. Federal salary range forSenior Staff Fellowship is $32,000 to$57,650.Contact:

Carl Merril, M.D., ChiefLaboratory of Biochemical GeneticsNational Institute of Mental Health

Neuroscience Center atSt. Elizabeth's, Room 131

2700 Martin Luther King Jr, Ave., S.E.Washington, D.C. 20032Phone: (202) 373-6081

Send curriculum vitae, a descriptionof research experience and names ofthree references.NIMH is an Equal Opportunity Employer

m a

POSITIONS OPEN

RESEARCH ASSISTANT PROFESSOR AND APOSTDOCTORAL. Research positions are immedi-ately availabl to work with molecular biology ofnuclearretinoid receptors. A doctorate in an appropriate fieldwith experience in molecular biology, e.g., cloning,Northern blots, recombinant DNA techniques, charac-terization ofDNA-binding protein desirable. Location isvery desirable intermountain city. Send resume and threereferences before 15 May 1991, to: Dr. R. P. Sharma,Toxicology Program, Utah State University, Logan,UT 8432216005 Equal Opportunity/Afrlmative ActionEmployer.

RESEARCH SCIENTIST. Applicants are invitedfor a research scientist position. Candidates must haveM.D. and/or Ph.D. degree. Strong background in im-munohistopathology is required. Previous experience inhybridomas, antib research, and tissue culture tech-nologies desirable. PIecase submit curriculum vitae, pub-lications, and names of three referees to: Arie H. Bartal,M.D., D.Sc., ImmunoSciences, Inc., 160 CommunityDrive, Great Neck, NY 11021. FAX: 516-466-2666.Equal Opportunity/Affirmative Action Employer.

MEETINGS

INTERNATIONAL CONGRESS OF PYTO-THERAPY, 16 to 19 October 1991 at Shilla Hotel,Seoul, Korea. Sponsors: Aloe Research FoundationU.S.A. and Pharmaceutical Society of Korea. The con-gess will be a forum for discussions and interactions

tween individuals from academia, industry, govern-ment, and business. Basic and clinical research studies ofaloe, kampo and other plant medicinal substances asmodifiers of neurologic, aging, immunologic, inflamma-tory, anti-microbial, and tumor activities will be present-ed. Invited presentations plus free communication plat-form and poster sessions are planned. Requests forabstracts (due July 1991) and congress information: Dr.Wendell D. Winters, Congress Chairman, Depart-ment of Microbiology, University of Texas HealthScience Center, 7703 Floyd Curl Drive, San Antonio,TX 78284-7758. Telephone: 512-567-3930 or FAX:512-567-6612.

ANNOUNCEMENTSRESEARCH AWARDS

The International Life Sciences Institute ResearchFoundation (ILSI Research Foundation) announces thatone award for a basic research project in TOXICOLO-GY or ENVIRONMENTAL HEALTH (to includehuman nutrition), of up to $100,000 over 3 years, willbe made in 1992. The purpose of the award is toencourage an innovative new investigator in basic bio-medical sciences to apply modem knowledge and tech-niques to basic problems related to comparative toxicol-ogy or environmental influences on growth, develop-ment, and aging. The dosing date for applications is 3September 1991. For further information, write: AwardAdministrator, ILSI Research Foundation, 112616th Street, N.W., Suite 100, Washington, DC20036.

THE ROSENSTIEL SCHOOL OFMARINE AND ATMOSPHERIC SCIENCE

OF THEUNIVERSITY OF MIAMI

SEEKS NOMINATIONS FOR THEROSENSTIEL AWARD

The Rosenstiel Award is presented annually to recog-nize outstanding achievement and distinction in oceano-graphic science. The intent of the award is to recognizemid-career individuals who have contributed substantial-ly towards new directions or understanding in their field.This year's award (induding a prize of $5000) will bepresented for excellence in the fields of marine biology,iological oceanography, or fisheries. Nominations, i-

cluding curriculum vitae and the names of three referees,should be sent by 15 May 1991 to:

Rosenstiel Award Search CommitteeDivision of Marine Biology and Fisheries

Rosenstiel School of Marineand Atmospheric Science

University of Miami4600 Rickenbacker Causeway

Miami, FL 33149-1098

COURSES AND TRAINING

CAREER CHANGE OPPORTUNITYThis unique program offers the candidate with an

earned doctorate in the sciences the opportunity toobtain the Doctor of Optometry (O.D.) degree in twocalendar years. Employment opportunities exist in pri-vate practice, industry, education, and research. Contact:Dr. D. Chauncey, Prgram Director, AcceleratedProgram, The New England College of Optometry,Room S 424 Beacon Street, Boston, MA 02115.

ELEANOR ROOSEVELT INSTITUTE1991 SOMATIC CELL AND MOLECULAR

GENETICS WORKSHOPThe Eleanor Roosevelt Institute will again offer a

Somatic Cell and Molecular Genetics Workshop, 15 to28 July 1991. This NCI-supported laboratory courseprovides a combined somatic cell and molecular biologyworkshop experience. The course has been designed toprovide a "hands-on" introduction to the methodologyand concepts ofcurrent molecular biology procedures forscientists who need to exploit these techniques for theircontinuing research programs. The content of this work-shop also provides the basic techniques needed forresearchers interested in initiating genome mappingstudies. Included in the curriculum are: somatic celhybridization and mutant isolation, yeast molecular biol-ogy, isolation and analysis ofDNA and RNA, prepara-tion and in vitro translation of polyadenylated mRNA,DNA-mediated gene transfer, PCR, pulse-field gel elec-trophoresis, DNA sequencing, Western, Northern, andSouthern analyses, one- and two-dimensional gel electro-phoresis, and the preparation and screening of cDNAand genomic libraries. Principal investigators whose re-search interests focus on malignancy are particularlyinvited to apply. A registration fee of $200 will becharged and a per diem stipend is provided. Applicantsshould submit a letter descnbing how the workshop willassist their current research, along with curriculum vitaewhich lists publications (no abstracts) for the past 5 yearsonly, to: Lynda Fox, J.D., Administrative Coordina-tor, Somatic Cell and Molecular Genetics Workshop,Eleanor Roosevelt Institute, 1899 Gaylord Seet,Denver, CO 80206. Please do not send registration atthis time. Application deadline has been extended to 15May 1991. The Eleanor Roosevelt Institute is an EqualOpportunity/Aflirmative Action Institution and invites andencourages applicationsfrom women and minorities. Open toU.S. citizens and permanent residents only.

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SCIENCE, VOL. 252

SORGHUM BREEDER/RESEARCH CENTERMANAGER

Duties: Develops and manages a comprehensivesorghum breeding, testing, and research programto develop and improve the varieties of sorghum tobe grown in the southern and northern plains states.Insures goals for projects are accomplished inaccordance with prescribed priorities, time limita-tions, and budgetary limitations. Establishes a per-manent breeding station. Identifies and implementsappropriate breeding strategies to develop superiorinbred and hybrid sorghum plant characteristicssuch as yield, size, quality, maturity, and resistanceto drought, disease, and insect pests utilizing princi-ples of plant breeding and genetics. Selects germ-plasm and test sites for conducting and continuingthe breeding process research. Works closely withsales, production, statistical, agronomic, biotech,and applied biology staff to coordinate activities andinsure the best available germplasm selection tech-niques and production practices for breeding andproducing products for prescribed areas. Reviewsstaffing requirements for projects, recruits, andsupervises 2-3 full-time technical staff and approxi-mately 10 part-time staff.Special Requirements: Graduate or on-the-job re-search experience with U.S. and exotic sorghumgermplasm and breeding techniques. Demonstratedability to use electronic data collection devices(Polycorders) and SAS. Specific knowledge, asevidenced by course instruction or on-the-job train-ing, of germplasm and hybrid needs for the Texaspanhandle, Kansas and Nebraska.Ph.D. in plant breeding and genetics or a relatedfield required. Annual salary $38,513.Apply at the Texas Employment Commission, Plain-view, Texas, or send resume to the Texas Employ-ment Commission, TEC Building, Austin, Texas78778, J.O. #6344360.Ad Paid by an Equal Employment OpportunityEmployer.

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