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POSITIONS OPEN

The Department of Biochemistry, Duke UniversityMedical Center, invites applications for the position ofASSISTANT PROFESSOR (tenure track). The per-son will be expected to establish a strong independentresearch program and to teach both medical and graduatestudents. The field of interest is open. Send resume,summary of research interest, and three letters of refer-ence to: Dr. Robert L. Hill, Duke University MedicalCenter, Durham, NC 27710. Duke University is anEqual Opportunity/Afirmative Action Employer. The closingdate for receipt of applications is 15 April 1990.ASSISTANT PROFESSOR. Temporary position,

possibly renewable, beginning August 1990, for geneti-cist capable of teaching microbiology and introductorybiology at a mid-sized Catholic liberal arts college withsix biology faculty. Ph.D. required. Experience in under-graduate teaching desirable. Send resume, complete withtranscripts and three letters of reference, by 1 March1990 to: Gerald J. Koppes, Director of Human Re-sources, Loras College, Dubuque, IA 52004-0170.An Affirmative Action/Equal Opportunity Employer.

ASSISTANT PROFESSOROF TOXICOLOGICAL SCIENCES

The Division ofToxicological Sciences of the Depart-ment of Environmental Health Sciences, The JohnsHopkins University (JHU) School of Hygiene and Pub-lic Health, is seeking to fill tenure-track positions at theASSISTANT PROFESSOR level in the areas of envi-ronmental biochemical/molecular toxicology, neurotoxi-cology, and immunotoxicology. Candidates should havea background in toxicology and/or pharmacology and atleast 2 years of postdoctoral experience. The successfulcandidates will be expected to develop a vigorous, grant-supported research program using modern cellular, bio-chemical, and molecular approaches to studies on themechanisms of toxicity and to participate in the teachingactivities of the division. It is desirable that the researchinterests and activities of the candidates complementthose of others within the division which include: hepa-totoxicity, hepatocarcinogenesis, cancer chemopreven-tion, free radical-mediated toxicity in lung and bonemarrow, mechanisms of ototoxicity, neural receptor sig-nal transduction, toxicant effects on lymphokine produc-tion, and immune function assessment. Other areas oftoxicology would also be considered. Send curriculumvitae, the names of three references, and a brief summaryof current research activity and future research plans to:James D. Yager, Director, Division of ToxicologicalSciences, JHU School of Hygiene and Public Health,615 North Wolfe Street, Bainmore, MD 21205. TheJohns Hopkins University is an Equal Opportunity/AfirmativeAction Employer.

ASSISTANT PROFESSOR POSITIONDIVISION OF CHILD PSYCHIATRY

The Division of Child Psychiatry and Child Develop-ment, Department of Psychiatry and Behavioral Sciencesat Stanford University School of Medicine, seeks a childpsychiatrist to participate in its research, clinical, andteaching programs in pervasive developmental disorders.We are especially interested in expanding our emphasison molecular neurobiology; in particular, how genesregulate the development and function of the centralnervous system (CNS). We have an active and estab-lished program in molecular neurobiology ofCNS recep-tors and enzymes and a strong collaborative effort inmolecular genetics in severe developmental disorders.We seek a child psychiatrist with experience in molecularbiology to interact with existing academic programs andto develop research and clinicaprograms in autism andrelated developmental disorders. The position requiresan M.D. and Board eligibility/certification in child psy-chiatry. Candidates should have an advanced or equiva-lent training/experience in molecular biology, molecularneurobiology, or molecular genetics, and have a demon-strated interest in and commitment to research, teaching,and clinical service in pervasive developmental disorders.This is a tenure-track position at Stanford University atthe assistant professor level. Stanford University is committedto increasing representation of women and members of minoritygroups on its faculty and particularly encourages applicationsfrom such candidates. Applicants should forward curriculumvitae and the names of three referees within 4 weeks ofthe date of publication of this advertisement to: Dr.Roland Ciaranello, Chairman of the Search Commit-tee, c/o Departnent of Psychiatry and BehavioralSciences, Stanford Medical Center, Stanford, CA94305-1028.

POSITIONS OPEN

_~p UNIVERSITY OF MANITOBAFACULTY OF DENTISTRY

ASSISTANT/ASSOCIATE PROFESSORApplications are invited for a tenure-track position at

the rank of ASSISTANT OR ASSOCIATE PRO-FESSOR beginning 1 July 1990 in the Department ofOral Biology, Faculty of Dentistry, University of Mani-toba. The department is responsible for teaching basicbiological sciences, together with related areas in dentis-try, to undergraduate, graduate, and dental hygienestudents. Oral biology has active M.Sc. and Ph.D. pro-grams and members of the department conduct researchinto connective tissues, mechcsms of cell secretion,endocrine function, salivary physiology, microbial ecolo-gy and metabolism, and cranio-facial morphometry. Ap-plicants should be trained in biochemistry and/or cellbiology. The successful applicant will be expected toteach components of integrated courses in oral biologyand to pursue an active research program in her/his areaof expertise. Salary and academic rank commensuratewith qualifications and experience. Applicants shouldhave a Ph.D. degree.

Both women and men are encouraged to apply. In accordancewith Canadian immigration laws, priority will be given toCanadian citizens or permanent residents.

Applicants should submit their curriculum vitae and anoutline of their research goals, and arrange for threeletters of reference to be sent to: Dr. G. H. Bowden,Professor and Head, Department of Oral Biology,Faculty of Dentistry, University of Manitoba, 780Bannatyne Avenue, Winipeg, Manitoba, Canada,R3E OW2. Deadline for applications is 1 April 1990.

EAST TENNESSEE STATE UNIVERSITYASSISTANT PROFESSOR in Department of Mi-

crobiology for Ph.D. molecular biologist. Research expe-rience and applications in regulation of gene expressionrequired. Department strengths: cytokines, regulation ofcell function, regulation of viral genes, and microbialpathogenesis. Applicants must apply molecular biologytechniques to one or more of these areas, must establish/maintain independent and collaborative research pro-grams, and teach medical and graduate students. Non-tenure-track position. Competitive salary, start-up funds,location in geographically desirable area. Send curricu-lum vitae, statement of research interests, and threereference letters to: Dwight W. Lambe, Jr., Ph.D.,Chairman, Department of Microbiology, James H.Quillen College of Medicine, East Tennessee StateUniversity (ETSU), Box 19,870A, Johnson City, TN37614. ETSU is an Equal Opportunity/Afffinnative ActionEmployer.

ASSISTANT, ASSOCIATE,OR FULL PROFESSORPHYSICIAN-SCIENTIST

IN CARDIOVASCULAR RESEARCHResearch position is open on the staff of the Depart-

ment of Vascular Cell Biology and Atherosclerosis Re-search for an M.D. or M.D./Ph.D. interested in someaspect of lipoprotein metabolism, pathophysiology ofatherosclerosis, diabetes, peripheral vascular diseases, orthrombosis/hemostasis. The successful applicant will beexpected to establish an independent research programand form collaborative ties with both basic researchers inthe research institute and full-time physicians in suchclinical departments as endocrinology, pathology, hema-tology, cardiology, cardiac surgery, or vascular diseases.The extent ofinvolvement with patient care is negotiable.The available position offers a stimulating and supportiveenvironment for career growth, competitive salary, excel-lent fringe benefits, new laboratory facilities, and sub-stantial funds for relocating or establishing a researcheffort.The Cleveland Clinic Foundation employs over 700

full-time physicians with diverse expertise. The researchinstitute consists of nine departments with more than150 biomedical scientists including pre- and postdoctoraltrainees. Applications accepted immediately. Send curric-ulum vitae, statement of research interests, and names ofat least three references to: Paul E. DiCorleto, Ph.D.,Department ofVascular Cell Biology and Atheroscle-rosis Research, FF4, Cleveland Clinic Research Insti-tute, 9500 Euclid Avenue, Cleveland, OH 44195.

The Cleveland Clinic Foundation is an Equal OpportunityEmployer.

PERSONNEL PLACEMENT 5872 FEBRUARY 1990

POSITIONS OPEN

ASSISTANT PROFESSOR. Candidates must haveat least 2 years ofpostdoctoral training using neurophysi-ological techniques to study central monoamine systemsin whole brain, slice, and cell culture preparations.Expertise in pharmacology, biophysics, and the tech-niques of patch clamping, electrochemical identification,and anatomical tracing desirable. The candidate wouldbe expected to work in a collaborative setting where basicneuroscience findings are integrated with behavior, bothnormal and abnormal. Submit curriculum vitae, descrip-tion of future research program, and three letters ofreference by 15 March 1990 to: Benjamin S. Bunney,M.D., Department of Psychiatry, Yale School ofMedicine, 25 Park Street, Room 619, New Haven,CT 06519. Yale University is an Equal Opportunity/Afir-mative Action Emnployer atnd applications from women atndminority group members are specifically invited.

YALE UNIVERSITY/PETROLOGY. The Depart-ment of Geology and Geophysics invites applications foran ASSISTANT PROFESSOR position in the area ofmetamorphic/igneous petrology. We are particularly in-terested in field-based studies of regional-scale processes.Research areas may include, but are not restricted to, theevolution of orogenic belts, fluid and heat flow duringorogenesis, physico-chemical and kinetic constraints onthe history and evolution of metamorphic and igneousrocks, and the chronology of orogenic events. Theappointment will complement existing programs in sta-ble isotopic geochemistry, kinetics of geochemical reac-tions, tectonics of convergent margins, and processes ofgranitic magmatism.

Applicants should submit a letter of application, cur-riculum vitae, publications, and the names and addressesof at least three references to: Dr. Barry Saltzman,Chairman, Department of Geology and Geophysics,Yale University, P.O. Box 6666, New Haven, CT06520. Completed applications must be received by 1April 1990.

Yale University is atn Equal Opportunity/Affirmative ActionEmployer.

ASSISTANT/ASSOCIATE PROFESSORION TRANSPORT

The Hospital for Sick Children Research Institutewishes to hire an individual with research interests in iontransport. Preference will be given to applicants with aninterest in epithelial cells and/or electrophysiologic exper-tise. Applicants should submit curriculum vitae, a briefstatement of their research interests, and names of threereferences to: Dr. Hugh O'Brodovich, Director, Res-piratory Research, Hospital for Sick Children, 555University Avenue, Toronto, Ontario, Canada M5G1X8. Deadline: 15 March 1990.

The University of Chicago, Department ofAnthropol-ogyv, invites applications for a potential appointment tophysical anthropology. Specialty is open, though prefer-ence will be given to individuals whose research interestscomplement those already present within the depart-ment. Persons at an advanced ASSISTANT PROFES-SOR OR ASSOCIATE PROFESSOR level are espe-cially encouraged to apply. Individuals with active pro-grams will be viewed most favorably. Send curriculumvitae and addresses of references by 1 June 1990 to:Chair, Department of Anthropology, University ofChicago, 1126 East 59th Street, Chicago, IL 60637.Equal Opportuniity/Affirmative Action Employer.

ASSOCIATE SCIENCE ADVISERA Washington, D.C.-based national trade organiza-

tion seeks a versatile biologist or chemist with a back-ground in the medical sciences and at least 3 years ofexperience beyond the completion of a doctorate. Theideal candidate also will possess (or be willing to acquire)good skills with computers, data evaluation, informationmanagement, statistics, and verbal communication. Thework presents a significant opportunity for someone whowants to obtain experience and credentials in regulatorytoxicology and epidemiology, to make a transition fromacademia to the private sector, or to change careerdirection from laboratory research to analysis. The salarycan be as high as the mid-$50,000's with excellent fringebenefits. Send a brief cover letter, curriculum vitae, list ofpublications, and names of four references (with tele-phone numbers and addresses) to: Denise F. DcMan,President, Bench International Search, Inc., 116North Robertson Boulevard, Suite 503, Los Angeles,CA 90048.

POSITIONS OPEN

ASSISTANT PROFESSORBIOLOGY DEPARTMENTWILLIAMS COLLEGE

Tenure-track position beginning July 1990 for abroadly trained BIOLOGIST with strong interests inboth teaching and research. Development of a researchprogram capable of obtaining extramural funding andinvolving undergraduate students is expected. Normally,faculty members teach one course and two laboratory sec-tions each semester. Ability to teach in one or more of thefollowing areas is desired: molecular endocrinology, com-parative physiology, immunology, cellular physiology.

Ph.D. required, postdoctoral experience desirable.Please send curriculum vitae, statement of teaching andresearch interests, and three letters of reference by 15February 1990 to: Chairman, Search Committee, De-partment of Biology, Williams College, Williams-town, MA 01267.An Equal Opportunity/Affirmative Action Employer. Wil-

liams College especially welcomes applicationsfrom women andminority candidates.

ASSISTANT/ASSOCIATE PROFESSORMEDICAL MICROBIOLOGY

The St. Louis College ofPharmacy invites applicationsfor a full-time (9-month), tenure-track position in micro-biology starting fall of 1990. Applicants should possess aPh.D. in microbiology with special interest in medicalmicrobiology. Responsibilities include teaching coursesin microbiology and immunology for pharmacy studentsand a survey course for nursing students. Send curricu-lum vitae, graduate transcripts, and names, addresses,and telephone numbers of three references by 1 March1990 to: Dr. R. J. Cooper, Director, Division ofBiological Sciences, St. Louis College of Pharmacy,4588 Parkview Place, St. Louis,MO 63110. An EqualOpportunity Employer.

Lewis and Clark College invites applications for 1-yearsabbatical replacement position for a biochemist at thelevel of VISITING ASSISTANT PROFESSOR tobegin September 1990. A Ph.D. and commitment toteaching and under raduate research are essential. Suc-cessful teaching and research experience are preferred.Teaching responsibilities include the two-termbiochem-istry sequence, including laboratories, and a sciencecourse for nonmajors. Our ACS-approved department iswell equipped with modem biochemical instrumentationand a 300-MHz NMR.

All applicants should send a letter of application,curriculum vitae, (unofficial) undergraduate and gradu-ate transcripts, and letters from three references by 1March 1990 to: Professor James Duncan, Chair, De-partment of Chemistry, Lewis and Clark College,Portland, OR 97219. Affirmative Action/Equal Opportu-nity Employer.

CELL BIOLOGISTYALE UNIVERSITY

SCHOOL OF MEDICINEThe Department of Cell Biology, Yale University

School of Medicine, is accepting applications for tenure-track positions at the ASSISTANT, ASSOCIATEAND PROFESSORIAL levels with a flexible startingdate. The department's new laboratory facilities willenable us to expand and complement our existing strongresearch base. Candidates with an interest in develop-mental biology; regulation ofcell growth and differentia-tion; interactions between the extracellular matrix, mem-branes, and cytoskeleton; organelle biogenesis and traf-ficking; and image analysis at the light and electronmicroscopic levels are encouraged to apply. It is antici-pated that successful candidates will establish indepen-dent, externally funded research programs. The depart-ment requires teaching of cell biology and histology tomedical students and supervision o our graduate stu-dents. Candidates must hold the Ph.D. or M.D. degreesand have at least 2 years of postdoctoral experience.

Applicants should submit curriculum vitae, statementof research and teaching interests, and names of threereferences to:

Dr. James D. Jamieson, ChairmanDepartment of Cell Biology

Yale tfniversity School of Medicine333 Cedar Street

New Haven, CT 06510-0082Yale University is an Equal Opportunity/Affirmative Action

Employer.

POSITIONS OPEN

ASSISTANT/ASSOCIATE PROFESSOR. TheDepartment of Pathology and Laboratory Medicine atThe Medical College of Pennsylvania (MCP), Philadel-phia, is recruiting for three tenure-track positions towork with a multidisciplinary cancer research group. Thesuccessful candidate is expected to have or to develop anindependent research program and to collaborate withother members of the group. Candidates must have anM.D. or a Ph.D. degree. Preference will be given toindividuals whose research involves the molecular basisof tumor genes and gene products, growth factors andreceptors, or tumor cell interactions with the host matrix.Salary and rank are competitive and commensurate withrank and experience. Candidates should submit curricu-lum vitae and summary of research interests to:

Barbara F. Atkinson, M.D.Professor and Chairman

Department of Pathology and Laboratory MedicineMedical College of Pennsylvania

3300 Henry AvenuePhiladelphia, PA 19129

Three letters ofrecommendation should be sent direct-ly by the referees to the above address. MCP is anAffirmative Action/Equal Opportunity Employer.

AQUATIC ECOLOGIST, ASSISTANT OR AS-SOCIATE PROFESSOR. A tenure-track research po-sition (70% research, 20% teaching, 10% service) isavailable at the University of Oklahoma Biological Sta-tion, with academic appointment in the Department ofZoology. The successful candidate will be expected toestablish a strong research program in residence at thebiological station, to complement ongoing faculty re-search in biology/ecology of reservoir and/or streamorganisms. Completed Ph.D. is required. Postdoctoralresearch experience, quality publications, strong quanti-tative and computer skills, and demonstrated ability toattract research funding are desirable. Forward curricu-lum vitae, reprints, description of research interests, andfour letters of recommendation to: Dr. Loren G. Hill,Director, University ofOklahoma Biological Station,Kingston, OK 73439. Screening of applicants willbegin 20 February 1990 and continue until the positionis filled. The University of Oklahoma is an AffirmativeAction/Equal Opportunity Employer. Qualified women, mi-norities, and disabled persons are encouraged to apply.

BIOLOGYASSISTANT PROFESSOR, microbiology. Appli-

cations are invited for a tenure-track position in theDepartment of Biology beginning in fall of 1990. Thecandidate should have a Ph.D. in microbiology or relatedarea, be familiar with latest bio-instrumentation, have astrong commitment to undergraduate teaching, and havea desire to develop a research program with undergradu-ates. Teaching responsibilities include a course in micro-biology and one in instrumentation, involvement in theintroductory biology program, and possible involvementin human anatomy lab.

Applicants should submit a letter of application, cur-riculum vitae, description of research interests, tran-scripts, and three letters of reference by 30 March 1990to: Martha A. Farver-Apgar, Director of Personnel,Elizabethtown College, One Alpha Drive, Elizabeth-town, PA 17022. Afirmative Action/Equal OpportunityEmployer.

BIOLOGY TEACHING POSMIION. The Bio-logical Sciences Interdepartmental Program and the De-partment of Microbiology at North Carolina State Uni-versity (NCSU) invite applications for a 9-month, ten-ure-track position at the ASSISTANT PROFESSORlevel. Principal duties will involve lecturing to largeclasses, student advising, and other assigned teachingduties in multisection introductory biology courses andmicrobiology classes as appropriate. Requirements in-clude a Ph.D. in microbiology, a broad background inthe biological sciences, and demonstrated effectiveness incommunicating with large classes. The person selectedwill be expected to develop a productive research pro-gram in microbiology. Send curriculum vitae, statementof research goals, statement of teaching experience andpotential to work in the described program, undergradu-ate and graduate transcripts, and three letters of recom-mendation before 28 February 1990 to: Dr. Charles F.Lytle, Coordinator, Biological Sciences Interdepart-mental Program, Box 7611, NCSU, Raleigh, NC27695-7611. NCSU is an Afirmative Action/Equal Op-portunity Employer.

SCIENCE, VOL. 247588

POSITIONS OPEN

CELLULAR AND MOLECULARPHYSIOLOGY

THE UNIVERSITY OF IOWACOLLEGE OF MEDICINE

Applications are invited for openings to be filled at theASSISTANT, ASSOCIATE, or FULL PROFES-SOR level. Applicants should have a strong record ofresearch accomplishment utilizing molecular biology, cellbiology, protein chemistry, or electrophysiology. Whilewe are particularly interested in individuals studyingmechanisms of signal transduction, stiucture and func-tion of membrane proteins, and regulation of geneexpression, quality ofresearch and ability to complementexisting strengths in molecular endocrinology, mem-brane biology, and cellular neurophysiology are of pri-mary importance. Substantial start-up funds for equip-ment, personnel support, and supplies are available.Excellent opportunities exist for participation in estab-lished thematic interdisciplinary programs. Rank andsalary will be based on academic and research record.Minimum requirements include Ph.D. or M.D. degreeand 2 years of relevant postdoctoral training. Applicantsshould send curriculum vitae, a statement of researchinterests and plans, representative publications, andnames and addresses of at least three references. Screen-ing will begin 1 March 1990.

Dr. Kevin CampbellChairman, Cellular and Molecufar Physiology Search

Department of Physiologv and BiophysicsHoward Hughes Macal Institute

The University of Iowa College of MedicineIowa City, IA 52 2

T'he Utniversity of Iowa is an Equal Opportunity/Afirma-tive Action Employer. Women and minorities are encouraged toapply.

THE UNIVERSITY OF THE WEST INDIESST. AUGUSTINE, TRINIDAD

Applications are invited for the following vacancies:ZOOLOGY: (i) CHAIR, all major disciplines will be

considered; (ii) SENIOR LECTURER/LECTURER,entomologist.CHEMISTRY: SENIOR LECTURER/LECTUR-

ER in physical chemistry with expertise in spectroscopy.Annual salary ranges: chair, TT$91,788 to 111,372;

senior lecturer, TT$69,180 to 86,352; lecturer,TT$54,708 to 77,604. Pensions, passages, housing al-lowances, study and travel grant, etc. Send applicationsnaming three referees and detailing qualifications andexperience as soon as possible to: Registrar, The Uni-versity of the West Indies, St. Augustine, Trinidad,West Indies. Further particulars sent to all applicants.The University of Queensland, Brisbane, Australia,

invites applications for the CHAIR IN ANATOMYwhich wif be made available by the retirement of Profes-sor G. S. Molyneux. Applicants must have an outstand-ing record of research in a relevant field of anatomy suchas cell biology, neurobiology, embryology and reproduc-tive anatomy, functional anatomy, and comparative anat-omy. This should be supported by a distinguished recordof teaching at the undergraduate and postgraduate level.The appointee will be expected to carry out research andto provide leadership in the scholarly activities of thedepartment, particularly in the promotion of high stan-dards and encouragement of research and postgraduatestudies. The appointee will be offered the opportunity toassume headshsp of the department with a frst term ofoffice on commencement of duty, thereafter according tothe administrative rules of the university. The depart-ment maintains a wide ranse of interactions with otherdepartrnents in the biological and health sciences andcontributes to undergraduate and postgraduate teachingin the Faculties of Science, Medicine, Dentistry, andVeterinary Science. For fiuther information, please con-tact: Professor C. J. Hawkins, Pro-Vice-Chanccllor(Biological Sciences), telephone: 07-377-2384. Thesalary or a professor is A$65,837 per annum. Super-annuation, access to special studies programs, and as-sistance with relocation costs are provided. Applicationforms and firther details may be obtained from:Appointments (37430), Association of Common-wealth Universities, 36 Gordon Square, LondonWClH OPF, England. Please forward an original pluscopies of application and r6sume to: The Director,Personnl Services, The University ofQueensland, St.Lucia 4067, Australia, by 2 March 1990. ReferenceNo. 58789. Equal Opportunity in Employment is univer-sity policy.

2 FEBRUARY I990

SmithKline Beecham Pharmaceuticals, a worldwide leader in pharmaceuticalresearch, is seeking a scientist to conduct basic and applied research programsdirected at understanding:* mechanisms of metabolism of novel therapeutic agents, in vitro* the effects of novel therapeutic agents on cytochrome P450 and other drug

metabolizing enzymes.The position offers substantial opportunity for collaboration with other scientistsinvolved in the discovery and development of novel therapeutic agents. As partof multi-disciplinary project teams, the scientist will be expected to provide thedrug metabolism perspective to fellow research scientists. Since the scientist willassume a high degree of project related responsibility, the position will also drawheavily upon individual scientific initiative, independence and innovation.Excellent interpersonal and communication skills are critical. Publication andpresentation of research findings are strongly encouraged.All positions require a Ph.D. in Biological or Chemical Sciences and a workingknowledge of state of the approaches to in vitro drug metabolism studies.Additional experimental experience with purified isozymes of cytochrome P450is preferred. Experience in bioanalytical methods development including HPLCand GC and in analysis of drugs and their metabolites in biologic fluids is required.Based in a state of the art research facility in suburban Philadelphia near ValleyForge, PA, SmithKline Beecham provides a stimulating, collegial atmosphere withextensive scientific resources available to each scientist. We offer an attractivecompensation/benefits/relocation package. For confidential review, pleaseforward your CV to Liz McKendry, L-113, SmithKline Beecham Pharmaceuticals,P.O. Box 1539, King of Prussia, PA 19406-0939. We are an Equal OpportunityEmployer, M/F/H/V.

NATIONAL UNIVERSITY OF SINGAPOREDEPARTMENT OF PHYSIOLOGYApplications are invited for teaching appointments in theDepartment of Physiology.

Candidates should have a PhD or equivalent degree and have at least two years of postdoctoral experience inone of the following areas:

(a) aspects of cellular and molecular physiology related to the regulation of cell growth and differentiation;(b) mechanism of action of hormones and hormone antagonistsThe appointee will be expected to develop an independent research programme in his own area of interestand be able to teach at undergraduate and postgraduate levels.Gross annual emoluments range as follows:

Lecturer S$50,390 - 64,200Senior Lecturer S$58,680 - 100,310Associate Professor S$88,650 - 122,870

(US$1.00 = S$1.94 approximately)The commencing salary will depend on the candidate's qualifications, experience and the level ofappointment offered. In addition, appointees with a basic medical degree and an approved higher academic/professional qualification may opt to retain consultation fees up to 60% of their annual gross salary or toreceive a fixed annual allowances as follows:

Lecturer S$6,000/9,000Senior Lecturer S$15,000Associate Professor S$2 1,000

Leave and medical benefits will be provided. Depending on the type of contract offered, other benefits mayinclude: provident fund benefits or an end-of-contract gratuity, a settling-in allowance of S$1,000 orS$2,000, subsidised housing at nominal rentals ranging from S$100 to S$216 p.m., education allowancefor up to three children subject to a maximum of S$10,000 per annum per child, passage assistance andbaggage allowance for the transportation of personal effects to Singapore.Applications forms and further information on terms and conditions of service may be obtained from:

The Director The DirectorPersonnel Department North America OfficeNational University of Singapore National University of Singapore10 Kent Ridge Crescent 55 East 59th StreetSingapore 0511 New York, N.Y. 10022, U.S.A.

Tel: (212) 751-0331

Enquiries may also be sent through BITNET to PERSDEPT @ NUSVM, or through Telefax: (65) 7783948

POSITIONS OPEN

DEAN OF SCHOOL OF GRADUATESTUDIES AND ASSOCIATE

VICE PRESIDENT FOR RESEARCHWRIGHT STATE UNIVERSITY

As the chief executive officer of the School of GraduateStudies, the dean develops and maintains quality gradu-ate education and related outreach programs for WrightState University, a metropolitan university with over17,000 students including more than 3,400 graduate andprofessional students, master's degrees in most disci-plines, and 4 doctoral degrees. The dean shares responsi-bility of appropriate standards for existing graduate-levelprograms, including new and continuing accreditation.The dean also facilitates graduate student recruitment,graduate admissions and records, and graduate fellow-ship programs. The dean, who reports to the vicepresident for academic affairs, represents the university tothe Ohio Board of Regents regarding all graduate studiesand research programs. As associate vice president forresearch, the dean represents the university to externalconstituencies on matters regarding research and eco-nomic development of the metropolitan area. WrightState now ranks third among state universities in Ohiowith over $12 million in external funding for researchand sponsored programs. The dean initiates and reviewsall policies related to the School of Graduate Studies,including the policies and compliance/assurances issuesof the Office of Research and Sponsored Programs, andleads and works closely with Graduate and ResearchCouncils in the area of policv development. Qualifica-tions include an earned doctorate; teaching, research, andservice accomplishments commensurate with a tenuredfaculty appointment at the rank of professor; a provenrecord of scholarly activity; extensive experience in gar-nering external research support; a commitment to re-search and graduate education; evidence of strong mana-gerial skills; ability to negotiate with government agen-cies, businesses, and industry; interest in applications ofresearch through technology transfer; and strong inter-personal skills to deal effectively with diverse groups.Screening begins on 1 March 1990, for position available1 Julv 1990, and continues until position is filled. Salarynegotiable. Include a statement expressing candidate'sphilosophy of graduate education and research, a resume,and the names, addresses, and telephone numbers of fivereferences. Search Committee will request letters ofreference. Send nominations and applications to: Dr.James E. Brandeberry, Chair of Search Committee,College of Engineering and Computer Science,Wright State University, Dayton, OH 45435. Wri,htState Unit'ersity is att Equal Opportntiity/Affirnative ActiottEtmployer.

@t) WRIGHT STATE UNIVERSITYDAYTON, OHIO 45435

DEPUTY DIRECTOROCEAN DRILLING PROGRAMTEXAS A&M UNIVERSITY

The Ocean Drilling Program at Texas A&M Universi-tv invites applications for the position of deputy director.Applicants should have an earned doctorate, preferablyin the field of marine geology and geophysics. In addi-tioil to distinguished research accomplishments, includ-ing seagoing experience on research vessels, the success-ful applicant should possess exceptional qualities ofleadership and interpersonal skills, as well as extensiveexperience in scientific management.The position requires interaction with senior level

scientists and engineers from the world's principal earthand ocean science institutions and government agencies,embassv personnel, and U.S. funding agencies in theconduct of a major international earth science program.The position will also present the opportunity for

strong interaction at the departmental level within one ofthe departments (Geology, Geophysics, or Oceanogra-phy) of the College of Geosciences at Texas A&MUniiversity.

Letters of application should include a resumn withthree references and be forwarded to:

Supervisor of PersonnelOcean Drilling ProgramTexas A&M University1000 Discovery Drive

College Station, TX 77843Texas A&M University is atn Equial Opportutnity/Affirna-

titve Actiotn Employer.

POSITIONS OPEN

CELL CULTURE TECHNICAL CORE DIREC-TOR. Ph.D. to supervise a cell culture core facility at theUniversity of Pennsylvania. Candidates should have atleast 5 years of experience with cell culture includinggrowth of a variety of cell lines, quality control of mediaand sera, and mycoplasma testing, as well as experience indirecting laboratory personnel and ordering of supplies.Knowledge of computers and business administrationwould be advantageous. Send resume to: Dr. RogerKennett, University of Pennsylvania, 475 ClinicalResearch Building, Philadelphia, PA 19104-6145.Equal Opportunity/Affirmative Action Employer.

ECOTOXICOLOGISTExxon Biomedical Sciences, Inc., has an immediate

opening for a qualified individual specializing in ecotoxi-cology and environmental hazard assessment. The suc-cessful candidate will have a Ph.D. in ecotoxicology or inan environmentally related field with 0 to 2 years ofpostdoctoral experience. Experience in or a knowledge ofthe application of both effects and fate data to real worldconcerns as well as knowledge ofregulatory requirements(TSCA/PMN) would be desired.Exxon Biomedical Sciences, Inc., performs both con-

sulting and laboratory toxicology for affiliates around theworld. Its resources include state-of-the-art aquatic toxi-cology, environmental chemistry, and mammalian toxi-cology laboratories. The candidate will perform as astudy monitor and internal consulting toxicologist. Cli-ent interactions are an important aspect of our work;thus, we are also seeking an individual who has excellentcommunication skills. Please forward resume to:

Christine Ramos, Human ResourcesExxon Biomedical Sciences, Inc.CN 2350, Mettlers Road

East Millstone, NJ 08875-2350Equial Opportntity Emnployer, M/F/H/V.

ENVIRONMENTAL SCIENCE. Huxley Collegeof Environmental Studies, Western Washington Univer-sity (WWU), will fill two tenure-track positions inenvironmental science, with special emphasis on PacificNorthwest watershed studies. Ph.D. required; rankopen. Position (i): half-time administrative duties asdirector, Institute of Watershed Studies; half-time teach-ing duties. Position (ii): full-time teaching position.Persons with specializations in terrestrial or aquaticecological systems encouraged to apply. Seek effectiveteachers and scholars with interdisciplinary orientation.Applicants for director position should have record ofsuccessful administration. Send letter of application;curriculum vitae; copies of representative publications;and names and telephone numbers ofthree references to:John Miles, Dean, Huxley College, Western Wash-ington University, Bellingham, WA 98225. Appli-cants should specify which position sought. Review ofapplications commences 2 March 1990, and will contin-ue until positions are filled, fall of 1990. WWU, throughAffirnative Actiotn goals, seeks catndidates to atugment diversity ofthe faculty in teachitig atid scholarship. Wometn atid mitnoritiesare encouraged to apply. WWU is atn Affirnative Actiont/EquialOpportunity Emnployer.

ENVIRONMENTAL CHEMISTExxon Biomedical Sciences, Inc., has an immnediate

opening for a qualified individual specializing in environ-mental chemistrv. The successful candidate will have aPh.D. in environmental chemistry or a related field, and1 to 3 years of practical experience in analytical methodand protocol development for analysis of environmentalsamples in water, soil/sediment, and fish tissues. Inaddition, the applicant should have a knowledge ofEPAmethodologies for conducting effluent toxicity identifica-tion and reduction evaluations and standard methods forcontaminant analysis.The successful candidate will act as a consultant to our

ecotoxicologists and to our affiliates on matters pertain-ing to the assessment of environmental hazards associat-ed with products, effluents, hazardous wastes, etc. byproviding analytical expertise to the design and interpre-tation of these programs. Client interactions are animportant aspect of our work, and thus, we are seekingan individual who has excellent communication skills.Please forward resume to:

Christine Ramos, Human ResourcesExxon Biomedical Sciences, Inc.

Mettlers Road, CN 2350East Millstone, NJ 08875-2350

Equial Opportntity Employer M/F/H/V.

POSITIONS OPEN

JOHN BARDEEN ENDOWED CHAIR INELECTRICAL AND COMPUTERENGINEERING AND PHYSICSCOLLEGE OF ENGINEERINGUNIVERSITY OF ILLINOISURBANA-CHAMPAIGN

The College of Engineering at the University ofIllinois is seeking nominations and applications for theJohn Bardeen Endowed Chair in Electrical and Comput-er Engineering and Physics sponsored by the SONYCorporation.The successful applicant must be a distinguished scien-

tist who has attained international recognition and whohas also demonstrated a commitment to excellence inteaching.The funds for the endowed chair will provide funding

for advanced research in the many fields of electrical andcomputer engineering and physics, and also cover facili-ties and specialized course development, experiment ac-quisition, and compensation for staff and assistants.The candidate seected as the holder of the chair shall

receive a joint appointment to the Department of Electri-cal and Computer Engineering and the Department ofPhysics, and will hold the chair for the length of his orher tenure at the University of Illinois. The salary isnegotiable. Proposed starting date is August 1990.Nominations or applications and requests for further

information should be directed to:Professor Jiri Jonas, Chairperson

Search Committee for the Bardeen ChairUniversity of Illinois108 Noyes Laboratory

505 South Mathews AvenueUrbana, IL 61801

Telephone: 217-333-0710Applicants should submit curriculum vitae, with a list

of publications. Nominations and applications should bereceived by 15 April 1990 in order to receive fullconsideration.

The University of Illinois is atn Afirtnative Actiotn/EquialOpportunity Emnployer.

DIRECTORCANCER RESEARCH LABORATORY

Mount Sinai Medical Center, Miami Beach, Florida,Department of Surgery, is seeking a Ph.D. level immu-nologist with a strong background in tumor immunolo-gy to direct the cancer research laboratory. Responsibil-ities include monitoring reactivity to biologic responsemodifiers as well as developing murine tumor models forthese modifiers. Candidates should have a Ph.D. inimmunology with at least 4 years of experience. Salary isnegotiable. Curriculum vitae and three letters of refer-ence should be submitted to: Marc K. Wallack, M.D.,Chairman, Department of General Surgery, MountSinai Medical Center, 4300 Alton Road, MiamiBeach, FL 33140. Ant Equial Emnploymetit Opportunity/Affirnative Actiotn Emnployer.

FACULTY POSITION. Biologist, Ph.D. Teachingresponsibilities include introductory biology, cell biolo-gy, and microbiology in a 4-year, Christian, liberal artscollege in the Presbyterian tradition. Send curriculumvitae and statement of teaching and research interests to:Dr. Gregory D. Jordan, Acting Dean of the Faculty,King College, Bristol, TN 37620. Kitig College is anEquial Opportunity Employer.

FACULTY POSITIONSCELL AND MOLECULAR BIOLOGISTS

The Department of Surgery at the University ofConnecticut Health Center is seeking applications fortwo RESEARCH or tenure-track ASSISTANT PRO-FESSOR positions. One will be filled by a cell biologistwith cell culture experience and an interest in cell-cellcommunication and membrane-cytoskeleton interaction.The second position is for a molecular biologist withinterest in gene expression, molecular biology of signaltransduction, and transfection techniques. Positions in-clude laboratory space and start-up funds for initial yearsof program. Successful candidates will be expected toestablish independent, externally funded research pro-grams. Curriculum vitae and three letters of recommen-dation should be sent to: Ttacy K. McIntosh, Ph.D.,Department of Surgery, University of ConnecticutHealth Center, Farmington, CT 06032. The Universityof Connecticut is an Affirmative Action/Equal OpportunityEmployer, M/W/H.

SCIENCE, VOL. 247590

FACULTY POSITIONSMOLECULAR, CELLULAR ANDCLINICAL PHARMACOLOGY

The Department of Pharmacology and Experimental Therapeutics andthe Division of Clinical Pharmacology at the Medical University of SouthCarolina seek to fill up to seven positions at the assistant or associateprofessor level over the next two years. Applicants should have a Ph.D.and/or M.D. degree, successful postdoctoral experiences and the enthu-siasm and energy to develop independent research careers in anenvironment where collegiality and collaboration are important traditions.We are looking for scientists and scientists/physicians who plan to applytheir interests and capabilities in molecular genetics, protein chemistry,receptors, channels, signal transduction mechanisms or cell biology toproblems in basic and clinical pharmacology. We offer an environmentrich in senior level scientific and clinical experience, start up funds,laboratory space, a record of highly successful and continuing extramu-ral research funding and an array of important resources which include:both inpatient and outpatient NIH supported clinical research units (1000hypertensive patients); extensive analytical capabilities (e.g., 400 MHzNMR, triple quadrupole and new NSF-supported high mass, highperformance tandem mass spectrometers); and access to hybridoma,cell culture, synthetic organic chemistry, image analysis, and peptideand DNA sequencing and synthesizing facilities. We are committed to abroad spectrum of undergraduate teaching and predoctoral and post-doctoral training, with an excellent track record in the local environmentof teaching and student research awards. Send curriculum vitae, re-prints, list of references and a summary of career goals to:

Harry S. Margollus, M.D., Ph.D., ChairmanDepartment of Pharmacology and Experimental Therapeutics

orPerry V. Halushka, M.D., Ph.D., Director

Division of Clinical PharmacologyMedical University of South Carolina

171 Ashley AvenueCharleston, South Carolina 29425

An Equal Opportunity/Affirmative Action Employer.

ASSOCIATE RESEARCHSCIENTIST

Cellular Biochemistry/Molecular BiologyBristol-Myers Squibb, world headquarters for phar-maceutical research and development in Wallingford,Connecticut, is a state-of-the-art facility created for theencouragement of professional achievement and inter-disciplinary cooperation.

An excellent opportunity exists for an individual withan MS/BS in biochemistry, cell biology, molecularbiology or related area with 2 to 5 years experience inmolecular biology, biochemical, immunological andtissue culture techniques, including some/all of thefollowing: DNA and RNA isolation and characteriza-tion, chromatography, protein electrophoresis,fluorometry, ELISA and RIA. Position involves thestudy of peptide and protein growth factors, theirreceptors and signal transduction mechanisms in bothtumor cells and lymphocytes.

Bristol-Myers Squibb offers sustained growth, highlycompetitive salaries, extensive benefits and career sup-port. Our countryside location is convenient to Con-necticut cultural centers, New York andNew England.To apply, please send resume to: BRISTOL-MYERSSQUIBB COMPANY, Pharmaceutical Research &Development Division, Attn: MH299, P.O. Box 5101,5 Research Parkway, Wallingford, CI 06492-7661.An Equal Opportunity Employer MIFIH/V.

*z Bristol-Myers Squibb Company"Stronger Than Ever In Global Health Care"

NATIONAL INSTITUTES OF HEALTH

POSITIONS FOR STAFF FELLOWS(TENURE TRACK)

AND POST-DOCTORAL FELLOWS

1. TRANSGENIC MICE - Studies involving the genes ofHSV, HIV, EBV, receptors, and hormones; patho-genesis of viral infections and endocrine diseases.

II. POLYREACTIVE ANTIBODIES/CD5+ B CELLS -

Mechanism of polyreactivity; production andcharacterization of human monoclonal antibodies;biology of CD5+ B lymphocytes.

111. AUTOIMMUNE DISEASES - Cloning, expression andcharacterization of autoantigens involved in insulin-dependent diabetes mellitus, lupus erythematosus,rheumatoid arthritis, and Graves' disease.

Positions available immediately. Experience inmolecular biology desirable. Growing program withopportunity for Staff Fellows to have technical and/orpost-doctoral support. Salary commensurate withexperience (range $25,000 to $50,000 per year). SendCurriculum Vitae and names of references to Dr. LoisSalzman, Deputy Director, Intramural ResearchProgram, National Institute of Dental Research, NationalInstitutes of Health, 9000 Rockville Pike, Building 30,Room 121, Bethesda, MD 20892.

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

SENIOR CHEMISTEXPOSUREASSESSMENT

Midwest Research Institute (MRIJ isa well-established contract researchorganization with an outstanding reputation in the field ofchemistry.We are expanding our exposure assessment capability at ourheadquarter laboratories in Kansas City, Missouri, and are seeking aSenior Chemist with a broad technical base and a Ph.D. in Analyticalor Physical Biochemistry, or equivalent.Weare looking for leadershipqualities coupled with solid technical expertise in exposureassessment/human monitoring.

The successful candidate will contribute to the development anddirection ofexposureassessment research programs. Emphasiswill beon human exposure to environmertally significant contaminants, andon topics such as indoor air, consumer products, hazardous materials,and the use of experimental results to develop and validate models.Research efforts may range from the establishmentof exposure/doserelationships to the development ofmethods for quantifying exposureby specific routes, especially dermal exposure. We are seeking anexposure assessment expert to interact with clients and amultidisciplinary staff. This position will also prepare and reviewreports and proposals.

MRI offers a competitive compensation, benefits, and relocationpackage, in addition to a convenient location in an attractivemetropolitan setting. For immediate consideration, send resume toGD Ratcliff, at:

MIDWEST RESEARCH

INSTITUTEMRI@ ~~~~~425Wblker Blvd.Kansa Cty, Missouri 64110

_816} 753-7600

For more information see our recruiter at the Pittsburgh Conferencein New York City, March 5-8, 1990.

An Equal Opportunity Employer MIFIHIV

POSITIONS OPEN

BIOLOGY FACULTY. Colby-Sawyer College, asmall independent four year college located in the beauti-ful Dartmouth-Lake Sunapee area ofNew Hampshire, isseeking a faculty member whose primary responsibilitywill be in cell biology and genetics. Expertise in develop-mental biology and anatomy and physiology is desirable.Near completion of an advanced degree is required, as isthe demonstrated ability to teach elfectively. Position isopen August of 1990. Please send a letter of application,resume, and names of five references to: Director ofHuman Resources, Colby-Sawyer College, New Lon-don, NH 03257.

Equal Opportunity Employer.UNIVERSITY OF BRITISH COLUMBIADEPARTMENT OF ORAL BIOLOGY

BIOMATERIALSApplications are invited for a position at the level of

either ASSISTANT OR ASSOCIATE PROFESSORin the area of biomaterials. A tenure-track position willbe available on 1 January 1991, and is subject to finalbudgetary approval. Salary will be commensurate withexperience. Applicants must have a Ph.D. and the abilityto teach courses in dental materials. The ideal individualwould have an excellent research record and the ability toattract grant support. The opportunity exists for anhonorary appointment in either the Faculty of Science orEngineering. Applications should be received by 31 May1990. Applicants should send curriculum vitae, a sum-mary of research nterests, and the names and addressesof three references to: Dr. D. M. Brunette, Departmentof Oral Biology, Faculty of Dentistry, The Universityof British Columbia, 2199 Wesbrook Mall, Vancou-ver, BC, Canada V6T 1Z7. In accordance with Canadianimmigration requirements, preference will be given to Canadiancitizens and permanent residents of Canada. The University ofBritish Columbia is committed to the federal government'sEmployment Equity program and encourages applications fromall qualified individuals.

FACULTY OPENING IN PHYSICS(NUCLEAR PHYSICS)

UNIVERSITY OF CALIFORNIAAT BERKELEY

The Department of Physics at the University of Cali-fornia, Berkeley, and the Lawrence Berkeley Laboratory(LBL) expect to make a joint appointment in nuclearphysics at the ASSISTANT, the tenured ASSOCIATE,or the FULL PROFESSOR level, effective 1 July 1990;candidates in either theoretical or experimental nuclearphysics are encouraged to apply. The appointee willteach in the Physics Department and have researchfacilities in the Nuclear Science Division at LBL. Sum-mer research salary will be provided by LBL.

Applicants should send curriculum vitae, bibliography,statement of research interests, and list of references to:Professor P. Buford Price, Chairman, Department ofPhysics, University of California, Berkeley, CA94720, before 10 March 1990. The University of Califor-nia is an Equal Opportunity/Afirmative Action Employer.

The Department of Pathobiology, College of Veteri-nary Medicine, University of Tennessee, has a tenure-track FACULTY POSITION available for an EX-PERIMENTAL PATHOLOGIST. The successfulcandidate will be expected to emphasize the developmentof a strong independent and collaborative research pro-gram in the area of cellular and molecular pathobiotogyand the pathogenesis of disease. Abundant collaborativeresearch opportunities are available. The successful candi-date will also be expected to assist in the department'sprofessional and graduate teaching programs as well asgraduste research training. Time commitments to resi-dency training and departmental service responsibilitiesare expected to be minimal. D.V.M., Ph.D., or equiva-lent degrees with appropriate research training and expe-rience are essential.Academic rank and salary will be commensurate with

background and experieince, but we particularly encour-age application from junior candidates. Applications willbe reviewed beginning 15 March 1990. Informal inquir-ies are invited. Applicants should send curriculum vitae,three or more letters of reference, and a statement ofresearch and career goals to: Dr. Erby Wilkinson,Chairman of Search Committee, Departnent ofPathobiology, College of Veterinary Medicine, P.O.Box 1071, University of Tennessee, Knoxville, TN37901-1071. Telephone: 615-546-9230. The Univer-sity of Tennessee is an Equal Opportunity/Afirmative Action/Title IX/Section 504 Employer.

POSITIONS OPEN

FACULTY POSMON. A 12-month, tenure-trackappointment requiring research and teaching expertise isopen to individuals holding a Ph.D. in toxicology,pharmacology, or related discipline. Candidates with aD.V.M. degree and expertise in cellular and/or molecularlevel studies are desirable. Send curriculum vitae and astatement of research interests to: Dr. E. M. Bailey,Department of Veterinary Physiology and Pharma-cology, Texas A&M University, Coflege Station, TX77843-4466. Texas A&M University is an AfirmativeAction/Equal Opportunity Employer.

FACULTY POSITION: TRANSPLANTATION,BIOLOGY, AND IMMUNOLOGY. Permanent trackposition for persons with Ph.D. and/or M.D. degrees.Involves conducting an independent research programon some aspect of transplantation, biology (such asphysiology), and/or immunology with a focus towardtransplantation. Candidate expected to be competent inbasic immunology, to conduct an independent researchprogram, and be willing to participate with cliniciansinvolved in a large multi-organ transplantation program(liver, renal, pancreas, heart, lung, bone marrow). Willreceive academic appointment commensurate with his/her qualifications. Start-up funds for establishment of thelaboratory are available. Send curriculum vitae, a descrip-tion of research interests, and names of three referencesto: Dr. Keith Kelly, Chairman, Departnent of Sur-gery, Mayo Clinic, Rochester, MN 55905. An EqualOpportunity/Afirmative Action Institution.

TENURE-TRACK FACULTY POSITIONENVIRONMENTAL POLICY

The new School of Public Policy at the GeorgiaInstitute of Technology announces an anticipated posi-tion in environmental policy, beginning September1990. Rank is open.The school is searching for specialists in the analysis

and evaluation of environmental policies at the state,regional, national, or international levels. Specific areasof concentration may include environmental regulatorypolicy, contingent valuation/survey research, impactanalysis, environmental decision-making, or resourceanalysis in a substantive policy area. We would beespecially interested in applicants with expertise in multi-media effects of technological developments. Candidateswith strong skills in quantitative and qualitative researchmethodologies will be given special attention.The Ph.D. or equivalent degree is required at the time

of appointment. Send applications, curriculum vitae, andthree letters of reference to: Dr. Thomas N. Debo,Chair, Environmental Policy Search Committee, CityPlanning Program, Georgia Institute of Technology,Atlanta, GA 303320155. Closing date is 15 April1990.

Georgia Tech is a unit of the University System of Georgiaand an Equal Opportunity/Afirmative Action Employer.Women and minorities are especially encouraged to apply.

COLUMBIA UNIVERSITYDEPARTMENT OF BIOCHEMISTRYAND MOLECULAR BIOPHYSICS

The department is embarking on a program of hiringnew FACULTYMEMBERS and intends to fill tenuredand tenure-track positions.

Applications are invited from candidates with thePh.D. degree or its equivalent and appropriate postdoc-toral for positions in biochemistry and molecular bio-physics. In the area of biochemistry we are seekingcandidates with research interests in several disciplinesincluding: developmental biology, neurobiology, andregulation of gene expression in both eukaryotes andprokaryotes. We are particularly interested in personswhose research in these areas focuses on nucleic acid-protein interactions. In molecular biophysics, the areas ofparticular interest are three-dimensional structural analy-sis, protein folding, and RNA conformation.

Preference will be given to candidates with a strongrecord of research accomplishments. Interested candi-dates should submit curriculum vitae, bibliography, re-prints, and summary of current research and fiureresearch goals as wehl as three letters of reference. Thedepartment is especially interested in women and minoritycandidates. All applications should be addressed to:Chairman, Department ofBiochemistry and Molecu-lar Biophysics, Columbia University, Health Sciences,630 West 168th Street, New York, NY 10032.

Columbia University is an Equal Opportunity/AfirmativeAction Employer.

POSITIONS OPEN

MICROBIOLOGY/IMMUNOLOGYFACULTY POSMONS

Applications are invited for two full-time, tenure-trackfaculty positions at the ASSISTANT OR ASSO-CIATE PROFESSOR level in the Department ofMicrobiology and Immunology at the University ofColorado School of Medicine:MOLECULAR/CELLULARIMMUNOLOGIST:

Applicants should have training, interests, and skills inthe use of current molecular and cellular techniques forstudying the function and/or development of the im-mune system.MOLECULAR MICROBIOLOGIST: Applicants

should have training, interests, and skills in molecularapproaches to the study of bacterial pathogenesis.

Successful applicants will be expected to initiate andmaintain an active, independent research program; par-ticipate in the teaching of microbiology or immunologyto medical students; and become an active member in anestablished graduate training program. Laboratory spaceand start-up funds will be provided by the department.Candidates with a commitment to excellence in researchand teaching are encouraged to send curriculun vitae, astatement of research and teaching interests, and thenames of three references by 1 June 1990 to: Lewis I.Pizer, Ph.D., Professor and Chairman, Departmentof Microbiology/Immunology, Box B-175, Universi-ty of Colorado Health Sciences Center (UCHSC),Denver, CO 80262.UCHSC is an Equal Opportunity/Afirmative Action Em-

ployer. Women and minorities are encouraged to apply.FACULTY POSITION: MOLECULAR VIROL-

OGY. The Division of Molecular Virology at BaylorCollege of Medicine invites applications for a tenure-track position at the ASSISTANT OR ASSOCIATEPROFESSOR level. An innovative scientist is soughtwith research interest in replication or pathogenesis ofviral infections; appropriate topics include the molecularbiology of replication, chronic or persistent infections,and antivirals. Applicants should have a Ph.D. orM.D./Ph.D. with at least 2 years of postdoctoral experi-ence in molecular virology. The successful applicant isexpected to establish an independent research programand to participate in graduate training. This appointmentoffers an excellent opportunity to join an expandingacademic department with newly renovated laboratoriesand well-equipped support facilities. Current facultyresearch activities focus on the molecular basis of viralreplication, viral and cellular oncogenes, viral pathogene-sis, and modern approaches to viral vaccines. Sendcurriculum vitae, names and addresses of at least threereferences, a statement of current research activities, anda description of future plans by 1 April 1990, to: Dr.Janet S. Butel, Head, Division ofMolecular Virology,Baylor College of Medicine, Houston, Texas 77030.An Equal Opportunity/Affirmative Action Employer.

PHYSICS FACULTY POSITIONSThe Smith College Physics Department invites appli-

cation for two positions available in the fall 1990. Thefirst is a tenure-track position in experimental physics atthe ASSOCIATE OR ASSISTANT PROFESSORlevel. The candidate should have a Ph.D., an interest inteaching, and research interests amenable to collabora-tion with undergraduates. Preference will be given topersons with an established experimental program.Funds are available to start or extend a research project.The second position is a 1-year appointment at the rankof entry-level ASSISTANT PROFESSOR. Qualifica-tions are the same, except that the applicant need not bean experimentalist. Women and minorities are encouraged toapply. Located in western Massachusetts, Smnith Collegeis a leader in the education of women and has anoutstanding record in the number of professional womenphysicists who are alumnae. The Five College Consor-tium, comprised of Smith, Amherst, Mt. Holyoke, andHampshire Colleges and the University of Massachu-setts, provides a rich intellectual and cultural life forfaculty and students as well as additional collegial oppor-tunities in teaching and research. Curriculum vitae, state-ment of teaching and research interests and experience,and three letters of reference should be sent to: Profes-sor Bruce Hawkins, Chair, Department of Physics,Clark Science Center, Smith College, Northampton,MA 01063. Preference will be given to applicationsreceived before 15 February 1990. Smith College is anEqual Opportunity/Affirmative Action Institution.

SCIENCE, VOL. 247592

POSITIONS OPEN

FACULTY POSITION in the Biology Division ofthe California Institute of Technology (Caltech).

Caltech seeks a new faculty member in the BiologyDivision with research interests in biotechnology and itsapplication to current biological problems. Researchprograms might include the development and applica-tion of new theoretical treatments, techniques, or instru-ments to the study of macromolecules, chromosomes,genomic structure, genetic information, or genome evo-lution. The appointment may be at the ASSISTANT,ASSOCIATE, OR FULL PROFESSOR ranks, de-pending on experience. The appointment will initially befor 4 years and will be either tenure track or tenured,depending on experience. Send curriculum vitae and namesand addresses of three references to: Barbara Wold,Chair, Biotechnology Search Committee, Biology Divi-sion, California Institute of Technology, Pasadena, CA91125. Caltech is an Equal Opportunity Employer andwelcomes applications from minorities and women.

FACULTY POSITIONSMEMORIAL SLOAN-KETTERING

CANCER CENTERCELL BIOLOGY AND GENETICS

PROGRAMThe Memorial Sloan-Kettering Cancer Center invites

applications for several tenure-track junior and seniorfaculty positions in the Cell Biology and Genetics Pro-gram. This research program is one of four in theinstitute, and is expanding in the areas of cell cyclecontrol, differentiation, cell structure, intercellular recog-nition, and morphogenesis. The Cell Biology and Genet-ics Program is located in a new research building whichalso houses advanced facilities for protein and nucleicacid microchemistry, transgenic mice, and automatedmammalian cell micromanipulation. The members of theCell Biology and Genetics Program faculty are affiliatedwith the Cell Biology Graduate Program at CornellUniversity Medical College. The positions offered arehighly competitive with regard to start-up funds, labora-tory space, salary, and housing.

Eligible candidates should have a doctoral degree,postdoctoral experience, and demonstrate potential andability to develop an independent, imaginative researchprogram. Formal applications are invited from junior aswell as established investigators. Applications shouldinclude curriculum vitae, a list of publications, a summa-ry of research activities and research plan, and threeletters of recommendation. Applications should be ad-dressed to: Dr. Joan Massague, c/o Christine Brohme,Box #135, Memorial Sloan-Kettering Cancer Center,1275 York Avenue, New York, NY 10021.

Equal Opportunity/Afirmnative Action Employer.

UNIVERSITY OF MINNESOTACOLLEGE OF PHARMACY

FACULTY POSITION IN PHARMACEUTICSApplications are invited from persons holding a Ph.D.

in pharmaceutics/biopharmaceutics or other relevant dis-ciplines, or M.D. with research experience, for a 12-month, tenure-track position at the ASSISTANT PRO-FESSOR level. A professional degree in pharmacy is nota specific requirement. Preference will be given to indi-viduals with research interests broadly in the area ofdrugdelivery systems. The individual selected will be expectedto develop an active independent research programwhich attracts extramural funding, and to supervise theresearch activities and contribute to the instruction ofstudents in the graduate and undergraduate programs ofthe college. Postdoctoral experience is desirable. Theposition is available 1 July 1990.

Applicants should send, by 30 April 1990, curriculumvitae, a statement ofresearch interests, and the names andaddresses of three persons who can provide letters ofreference to:

David J. W. Grant, D.Phil.Department of Pharmaceutics

College of PharmacyUniversity of Minnesota

308 Harvard Street, S.E., 9-105 HSUFMinneapolis, MN 55455Telephone: 612-624-3956

Applicants with less than 5 years of experience sincethe award of the doctoral degree are required to submittranscripts of collegiate academic record.

The University of Minnesota is an Equal OpportunityEducator and Employer and specifically invites and encouragesapplicationsfrom women and minorities.

2 FEBRUARY 1990

Postdoctoral ResearchersGenentech, Inc., a leader in the field of biotechnology, has several Postdoctoralopportunities for research and taining available in the areas of:

* Cell Genetics* Molecular Biology* Protein Chemistry

* Developmental Biology* Cardiovascular Biology* Immunobiology

We expect Genentech postdoctoral fellows to conduct independent research inthe areas of our scientific interests, publish in the leading scientific journals,attend and present their work at scientific conferences and maintain closeties with the academic community.

Genentech, Inc. offers an attractive salary and benefits package coupled withthe opportunity to make a significant contribution to our organization. Forconsideraton, please send your resume to: Genentech, Inc., Attn: YvonneDavino, Dept. PD, 460 Point San Bruno Blvd., South San Francisco, CA94080. We actively support and promote affirmative action and equal em-ployment opportunity. Women and minorities are encouraged to apply.

Genenech,In&Geneneh Ina

Join A Well Respected Industry Leader.The Medical Research Division of American Cyanamid Company is recognized internationallyas a leader in the research and development of therapeutic compounds. The MolecularNeurobiologyGroup of the CNS Research Department has research projects focusing on the areas of CNSDegenerative Diseases, and Voltage and Ligand Gated Ion Channels. Our current expansion re-quires three Research Scientists (with at least two years' postdoctoral work) and three Postdoc-toral Scientists with the following qualifications:

RESEARCH SCIENTIST having strong molecular and cellular biology backgrounds to work witha team applying molecular techniques to the study of Alzheimer's Disease and other dementias.Respond to department MV.

RESEARCH SCIENTIST with a strong background in at least two areas including molecular biology,biochemistry or electrophysiology to work with a team applying protein biochemistry, molecularbiology and electrophysiological techniques to clone, express and study various K+ channels.Respond to department RZ.

RESEARCH SCIENTIST with a strongbackground in molecularbiology, biochemical pharmnacologyand/or electrophysiology to work with a team on our ongoing efforts to clone, express and studyvarious subtypes of the GabaA receptor/benzodiazepine/ Cl- channel complex. Respond to depart-ment MA.

POSTDOCTORAL SCIENTISTS (3) with strong background in moleculargenetics/biology andbiochemistry to work in ourAlzheimer's Disease program. Part of this program focuses on transcrip-tional regulation and post-translational processing of the amyloid gene [see e.g., PNAS 86:7606(1989)1. Respond to department SJ.Lederle is located in Rockland County on a 580 acre campus-like setting only 25 miles north ofNew York City. Starting salaries are very competitive and include comprehensive benefits. Forconsideration, send resume/c.v. with appropriate department code and the names and telephonenumbers of 3 references, to: Professional Employment Representative, Medical Research Divi-sion, Lederle Laboratories, Pearl River, NY 10965. An Equal Opportunity Employer M/F.

.l

POSITIONS OPEN

FACULTY POSITIONSLABORATORY OF TOXICOLOGY

HARVARD SCHOOL OF PUBLIC HEALTHThe Laboratory of Toxicology is searching for junior

faculty members at either the ASSISTANT PROFES-SOR OR ASSOCIATE PROFESSOR rank. Success-ful candidates will be expected to establish outstandingindependent research programs and to participate ingraduate student teaching and the training of postdoc-toral fellows. Candidates s-hould have research interests inthe molecular, genetic, or cellular mechanisms of toxicity,and complement the existing faculty whose activitiesfocus on the molecular mechanisms of mutagenesis,DNA repair genes, receptor-mediated toxicity, chemicalcarcmogenesis and tumor promotion, cell cycle regula-tion, and physiological and genetic responses to oxidativestress and other DNA-damaging agents. Excellent start-uF and support funds are available from the LaboratoryToxicoloyo.Send currnculum vitae, a statement ofresearch interests

and future plans, up to four representative reprints, andthe names of three evaluators to:

Associate Professor Leona SamsonLaboratory of Toxicology

Harvard School of Public Health665 Huntington Avenue

Boston, MA 02115Harvard University is committed to increasing representation

of women and minority members among its faculty and particu-larly encourages applications from such candidates.

The Duke University School of Forestry and Environ-mental Studies invites applications for the followingEverglades research management positions:

FIELD SITE MANAGERThis full-time research management position begins 1

March 1990. Candidates shoufd have an M.S. or Ph.D.with experience preferred in directing wetlands research.Person will work from West Palm Beach, Florida, labora-tory. Manager will be responsible for day-to-day projectoversight and monitoring of water q,uality, so, andhydrology research. Opportunities exist for individualresearch.

ASSISTANT FIELD MANAGERThis full-time position begins 1 March 1990. Candi-

dates should have a B.S. or M.S. in ecology or relatedfield. Person will work from West Palm Beach, Florida,laboratory. Assistant will be responsible for day-to-daymonitoring of water quality, soils, and hydrology re-search.

PREDOCTORAL FELLOWSHIPSThese are two fully funded positions, one available

immediately and one in June 1990, in wetlands ecology.Candidates should have an M.S. in ecology or relatedfield. The students will participate in Everades researchspecifically nitrogen and phosphorus cycling and cattailcompetition.Duke University offers highly competitive salaries and

benefits. Please send curriculum vitae and at least threeletters of recommendation to: Dr. Curtis J. Richard-son, Director, Wetland Centcr, School of Forestryand Environmental Studies, Duke University, Dur-ham, NC 27706. Applications from minorities and womenare encouraged.Duke University is an Equal Opportunity/Afirmative Ac-

tion Employer.GEOTECHNICAL ENGINEER

Manage hazardous waste projects which typically in-clude preparation of work plan, quality assurance projectplan, sampling and analysis plan, remedial investigation,and feasibility study. Assist other projects in such areas aslandfill design and construction and geotechnical aspectsofhazardous waste projects. Use computer programs andexisting software and computer techniques such as FiniteElement and other numerical analysis methods in solvinggeotechnical engineering and groundwater problems. Asneeded, work on hazardous waste sites including Level Bsites using self-contained breathing apparatus. Requiresan M.S. in civil engineenng with a major in geotechnicalengineering and 2½ years of direct experience in the jobbeing offered and as described. Salary offered: $38,000per year; 40 hours per week, 8 a.m. to 5 p.m., Monday toFriday. Send resume to: Illinois Department of Em-ployment Securty, 401 South State Street, 3 South,Chicago, IL 60605, Attention: Connie M. Evans,Ref. #V-IL-9868-E. An employer-paid ad.

FACULTY OPENINGIN EXPERIMENTAL SPACE PHYSICS

UNIVERSITY OF CALIFORNIAAT BERKELEY

The Physics Department of the University of Califor-nia at Berkeley expects to make an appointment at theASSISTANT, the tenured ASSOCIATE, or the FULLPROFESSOR level, effective 1 July 1991. If it isdesirable for the successful appointee to begin research atBerkeley prior to the appointment date, means to arrangean interim research appointment at the Space SciencesLaboratory will be explored.

Please send curriculum vitae, bibliography, statementof research interests, and list of references to: ProfessorP. Buford Price, Chairman, Physics Department,University of California, Berkeley, CA 94720, before10 March 1990. The University of Califonia is an EqualOpportunity/Afirmative Action Employer.

IMMUNOLOGIST, FACULTY POSITION. Afull-time, tenure-track position in the Pathology Depart-ment at the rank of ASSISTANT OR ASSOCIATEPROFESSOR. M.D. or Ph.D. with demonstrated lead-ership in teaching and research. Position includes Partici-pation in educational programs in department an hospi-tal service responsibility in immunopathology labora-tory. Successful candidate should be able to transferresearch activities and funding to Medical College ofGeorgia. Send curriculum vitae and references to: C.Robert Baisden, Chief, Section ofClinical Pathology,Medical College of Georgia, Augusta, GA 30912.Equal Opportunity Employer, M/F. Females and minorities areencouraged to apply.

IMMUNOLOGISTSThe Veterinary Infectious Disease Organization

(VIDO) at the University of Saskatchewan is expandingits immunology group and therefore has a number ofpositions vacant. These positions will be filled at variouslevels ranging from postdoctoral fellow to research scien-tists commensurate with qualifications and experience.The selected applicant should be able to demonstrate astrong background in areas such as molecular immunolo-gy, cellular immunology, vaccine development, or cellu-lar biology as they relate to the study of immunemechanisms of protection and pathogenesis of respira-tory and enteric diseases and mastitis.The applicants will be part ofa team ofimmunologists,

molecular biologists, and veterinarians investigatingmechanisms of pathogenesis of viruses and bacteria aswell as enhancing immunity and resistance to infections.Applicants should have a degree in microbiology, veteri-nary medicine, or immunology, together with a Ph.D. inimmunology. A strong interest in the application ofmodem immunologica and molecular biological tech-niques to the solutions ofproblems related to elucidationand control of infectious diseases of animals is essential.Inquiries and applications should be directed to:Dr. L. A. Babiuk, Associate Director (Research)

orDr. Manuel Campos, Program Manager

(Immunology)VIDO

124 Veterinary RoadSaskatoon, Saskatchewan, Canada S7N OWO

MAGNETOENCEPHALOGRAPHY (MEG)NEUROSCIENTIST

Albuquerque Veterans Affairs Medical Center(VAMC), University ofNew Mexico School ofMedicine(UNM), and Los Alamos National Laboratories(LANL) are seeking a neuroscientist to become a re-search scientist for the VAMC/LANL/UNM Center forMagnetoencephalography. The facility at VAMC in-cudes a seven-channel magnetometer in a magneticallyshielded room for human studies and a four-channelhigh-resolution microSQUID system for animal studies.Applicant must have a Ph.D. or M.D. with expertise insome area of neuroscience, including clinical neurophysi-ology. Applicant must be willing to work with a team toexp ore clinical and scientific applications ofMEG. Salarydependent upon applicant's experience. University ofNew Mexico academic title possible. Send resume andnames of three references to: Douglas Rose, M.D.,Medical Director, MEG Center, or Yoshio Okada,Ph.D., Scientific Director, MEG Center, Albuquer-queVA Medical Center, 2100 Ridgecrest Drive, S.E.,Albuquerque, NM 87108. An Ajirmative Acion/EqualOpportunity Employer.

HUMAN ENVIRONMENTAL PHYSIOLOGISTA faculty position is open at the ASSISTANT OR

ASSOCIATE PROFESSOR level for candidates witha solid publication record and experience working withhuman subjects. Opportunities are available to develop astrong research program in environmental physiology incollaboration with the Divisions ofPulmonary Medicine,Occupational Health, and Physiology. Please send curric-ulum vitae and statement of present and future researchplans to: Dr. Wayne Mitzner, Division of PhysioloDepartment of Environmental Health Sciences, theJohns Hopkins University School of Hygiene andPublic Health, 615 North Wolfe Street, Baltimore,MD 21205. Telephone: 301-955-3612. FAX: 301-955-0299. TheJohns Hopkins University is an AffirmativeAction/Equal Opportunity Employer.

MICROBIOLOGIST/VIROLOGISTAND MICROBIAL PHYSIOLOGIST

The Department of Biological Sciences of State Uni-versityofNew York (SUNY) Plattsburgh invites applica-tions for two tenure-track ASSISTANT PROFESSORpositions beginning fall of 1990. MICROBIOLO-GIST/VIROLOGIST (Box A): Ph.D. with broad back-round in microbiology, expertise in virology, molecularbiology, medical micro iology. MICROBIA PHYSI-OLOGIST (Box B): Ph.D. with broad background inmicrobiology, expertise in microbial ecology, toxicology,and/or plant microbe interactions. Underrepresented minor-ity scientists are highly encouraged to apply. SUNY Platts-burgh is located on Lake Champlain with easy access toMontreal and Burlington, Vermont. Closing dates forapplications is 1 March 1990 or until positions are filled.Applicants should send resume to appropriate box num-ber noted above, three letters of recommendation, andsummary of proposed research to: Chair, Search Com-mittee, c/o Office of Personnel/Affirmative Action,SUNY Plattsburgh, Box 1649-246, Plattsburgh, NY12901. SUNY Plattsburgh is an Equal Opportunity/Affirma-tive Aaion Employer.

MOLECULAR BIOLOGY OF HEMATOPOI-ETIC CELL DIFFERENTILATION. POSTDOC-TORAL research on the isolation and characterizationof genes expressed during the differentiation and loss oftumorigenicity of leukemic cells. Experience in cDNAcloning/subtractive screening/sequencing useful. Startwithin 9 months. Please send curriculum vitae to: Dr.Ruth Craig, Department of Physiology, Johns Hop-kins Univcrsity School of Medicine, Baltimorc,21205.

MOLECULAR BIOLOGIST AND BIOTECH-NOLOGIST. The National Research Council (NRC) isseeking a SENIOR STAFF OFFICER for its Board onBiology. Will develop and manage projects in basic andapplied biology and science policy. Requires a Ph.D. orequivalent in molecular biology, biological sciences, bio-technology or a related field and at least 4 years ofgovernment, industrial, or academic research and/or ad-ministrative experience. Science policy experience andworking knowledge of federal government highly desir-able. Demonstrated effective commnunication skills, re-port preparation skills, project and budget management,and committee interacnons required. We offer a salarycommensurate with experience and an exceptional bene-fits package. Please send resume in confidence to:NRC:/Board on Biology, HA 258 (OZ), 2101 Consti-tution Avenue, N.W., Washington, DC 20418. EqualOpportunity Employer.

MOLECULAR IMMUNOLOGY

Applications are sought for a tenure-track appoint-ment as ASSISTANT PROFESSOR in the Division ofTransplantation, Department of Surgery, at The OhioState University. Applicants should have intensive post-doctoral experience in a wide range of molecular biologytechniques. They should expect to work with interdisci-plinary research team to apply these molecular biologytechniques to current problems in experimental andclinical transplantation. Prior experience in transplanta-tion or immunology not necessary. Salary negotiabledepending on experience. Send curriculum vitae andstatement of research and career goals by 1 March 1990to: Charles G. Orosz, Ph.D., The Ohio State Univer-sity College of Medicine, Room 265, Means Hall,1655 Upham Drive, Columbus, OH 43210.

SCIENCE, VOL. 247S94

POSITIONS OPEN POSITIONS OPEN

MOLECULAR/CELL BIOLOGIST. Birning-ham-Southern College seeks to fill a 1-year sabbaticalreplacement position beginning 25 August 1990. Bir-mmgham-Southern College is a small, private liberal artscollege with a student enrollment of 1935. Teachingresponsibilities will include genetics, cell biology, intro-ductory biology for nonmajors, and a course in theapplicant's fieldaor related area. Ph.D. preferred. Individ-uals who will complete their Ph.D. byl September 1990will be considered. Send curriculum vitae, transcripts ofundergraduate and graduate education, and three ettersof recommcndation to: Dr. Irvin Penfield, Box A-1,Birmingham-Southern College, Birmin , AL35254. Applications accepted through 1 Apr 1990.Equal Opportunity Employer.

PESTICIDE OR ENVIRONMENTAL BIO-CHEMIST/ENTOMOLOGIST. The Department ofEntomology, Washington State University (WSU), in-vites applications and nominations for a research, tenure-track, assistant/associate entomologist position located atPuyallup, Washington. Conduct research on the behav-ior of insecticides and other pesticides in agroecosystemsofwestern Washington (additional information availableupon request). Ph.D. required in a biological science.Candidates should have experience or an active interest inpractical entomology and systems ecology. Applicationsaccepted through 31 March 1990. Send two copies ofyour entire application including: letter of application,statement of professional goals and research plan, curric-ulum vitae induding reprints of fivc relevant publica-tions, descriptions of research expericnce, and a listincluding phone numbers of five referees to: John J.Brown, Chair, Search Committee, Department ofEntomology, Washington State University, Pullman,WA 99164-6432. WSU is an Equal Opportunity/Afirma-tive Action Employer. Protected group members are encouragedto apply.

PROFESSOR OF MEDICINAI/BIOLOGICALCHEMISTRY AND CHAIRMAN OF PHARMA-CEUTICS (DRUG DELIVERY). An individual withmajor prior academic or equivalent experience commen-suratc with appointment at the professor level in theDcpartment of Medicinal and Biological Chemistry issought by the University of Toledo, Collee of Pharma-cy. An individual with interests in drug design and in thechemistry of novel, preferably modern, biotcchnological-ly derived drug-delivery systems is desired. Some addi-tional leadership skills are preferred, as there is anopportunity to help lead the activities of the newlyestablished Center for Drug Design and Developmentand, secondly, to establish a new department, underwhich additional growth is expected. Examination ofapplicants began 1 February 1990, but applications willbe accepted after that date and the position will remainopen until it is filled by a successful applicant. Send letterof interest, curriculum vitae, and names of three refer-ences to: Dr. Richard A. Hudson, Chairman, Depart-ment of Medicinal and Biological Chemistry, TheUniversity of Toledo, Collegc of Pharmacy, ToledoOH 43606. The University of Toledo is an AffirmativeAction/Equal Opportunity Employer.

Somatogen is a rapidly growing biotechnology com-pany invohred in the development ofrecombinant hemo-globin-based blood substitute products. We are locateddose to both the University of Colorado-Boulder andthe University of Colorado Health Sciences Center inDenver.PROTEIN CHEMIST. This position requires a

Ph.D. and at least 2 years of postdoctoral experience.Preference will be given to candidates who have a strongbackground in organic chemistry as well as in proteinstructure and function.MOLECULAR BIOLOGIST. This position re-

quires a Ph.D. and at least 2 years of postdoctoralexperience in the field of yeast molecular biology orgenetics. Preference will be given to candidates withexperience in the expression of heterologous proteins inyeast.

Please send curriculum vitae, and the names of threereferences by 15 March 1990 to:

Personnel Director, Departmcnt SSomatogen, Inc.

350 Interlocken Parkway, Suite 100Broomfield, CO 80021

NEUROPATHOLOGISTASSISTANT PROFESSOR, tenure-track position

available 1 July 1991. Board certification or eliglibility inanatomic pathology and neuropathology is required. Theposition includes diagnostic, teaching, and research re-sponsibilities. Send curriculum vitae and names of threereferences to: Pierluigi Gambetti, M.D., Division ofNeuropathology, Institute of Pathology, Case West-ern Rcserve University, 2085 Adelbert Road, Cleve-land, OH 44106.

PLANT COMMUNITY ECOLOGISTThe Department of Botany, University of Georgia,

invites applications and nominations for a tenure-trackposition beginning as early as September 1990. Theappointment will probably be made at the ASSISTANTPROFESSOR level, but appropriately alificd appli-cants can be considered at the ASSOCIATE PROFES-SOR level. Candidates are expected to conduct indepen-dent research in community ecology and to teach appro-priate courses in ecology. Applicants should submitcurriculum vitae, statements of research and teachinginterests, and reprints, and arrange for four letters ofreference to be sent directly to: Dr. Robert Wyatt,Department of Botany, University of Georgia, Ath-ens, GA 30602 by 15 March 1990.

An Equal Opportunity/Afirmative Action Employer.POSTDOCTORAL POSION. Molecular mecha-

nisms ofmcmbrane fusion: liposomes, viruscs, intra- andintcrcellular. Expericncc in physical biochemistry and cellbiology preferred. Scnd curriculum vitae, relevant re-pints, and threc letters of recommendation to: Dr. JoeBentz, Dcpartment of Bioscience, Drexel University,32nd and Chestnut Streets, Philadelphia, PA 19104.Equal Opportunity/Afirmative Action Employer.POSTDOCTORAL POSMIION. Available to study

enzyme regulation and amino acid metabolism. Expen-cnce in protein purification/characterization, HPLC,protein phosphorylation, and/or post-translational pro-tein modification desirable. Send curriculum vitae, state-ment of research interest, and three letters ofrecommen-dation to: Dr. Ralph Paxton, Dcpartment ofPhysiolo-gy and Pharmacology, Collge of Veterinary Medi-one, Auburn University, AL 36849. Aubunm Universityis an Affirmative Action/Equal Opportunity Employer. Minor-ities and women are encouraged to apply.

POSTDOCTORAL POSMONS. Two positionsavailable: (i) effects of ACIH and other factors onhuman adrenal steroidogenesis and LDL processing; (ii)human liver lipoprotein production. Research experiencewith some ofthe following required: RIA, cell culture,Western/Northern blot, and chromatography. Ph.D. orequivalent. Send curriculum vitae, research interests, andnames of three references to: C. Richard Parker, Jr.,Ph.D., Department of Obstetrics and Gynecolog,vUniversity of Alabama at Birngham (UAB), UAiStation, Birmingh AL 35294. UAB is an EqualOpportunity Employer.POSTDOCTORAL POSMONS. Available to

conduct research on RFLP analysis of ccreal crops.Applicants should have experience with standard molecu-lar biology techniques including doning and DNA se-quencing. Candidates with a Ph.D. in molecular biology,genetics, or plant breeding are encouraged to agply.Please send resume to: Sybi Paul, Deawrtment ofCropand Soil Environmental Scienecs Virginia Polytech-nic Institute and State University (VPI&SU), Blacks-burg, VA 24061. Telephonc: 703-231-6300.VPI&SU is an Equal Opportunity/Affirmative ActionEmployer.POSTDOCTORAL OPPORTUNITIES. In the

Los Angeles Area to join a multidisciplinary researchteam in the development of a liposome-encapsulatedhemoglobin (LEH) product to be used as a bloodrep,lacement fluid. One position, available immediately at

00 per year is for a Ph.D. with a background inLIPID BIOCHEMISTRY who will be involved withthe formulation and testing of the LEH product. Asecond postdoctoral slot will be for a Ph.D. in SYN-THETIC MEDICINAL CHEMISTRY to be in-volved in analog development of pharmaccutical agentscapable of modulating ule oxygen bind propertles ofhemoglobin. Send curriculum vitae and three names orletters of references to: Dr. Thomas G. Burke, City ofHope National Medical Centcr, Duarte, CA 91010.Tcelphonc: 818-359-8111, ext. 4501. City ofHope isan Equal Opportunity/Affirmative Action Employer.

2 FEBRUARY I990

POSTDOCTORALPOSITION

Applications are invited for a postdoc-toral position in the Department ofImmunology to study mechanisms of

antigen processing and presentation.This position will provide an excellentopportunity for interdisciplinaryresearch involving the departments ofmolecular cell biology and biophysics.A suitable candidate should have a

strong background in immunologyand/or biochemistry, cell biology,molecular biology. The postdoctoralappointment will be for two years.Candidates may have one or two yearsprevious postdoctoral experience.

Merck Sharp & Dohme ResearchLaboratories is located in Rahway,New Jersey approximately 25 milesfrom New York City. Our salaries, ben-efits and growth potential are excellent.Interested individuals should send theirresume and the names of three refer-ences to Ms. Susan F. Glinka, P.O.Box 2000, Merck & Co., Rahway,NJ 07065. An equal opportunityemployer in/f/v/h.

POSITIONS OPEN

RESEARCH ASSOCIATEThe Mineral Metabolism Section, National Instituteof Diabetes and Digestive and Kidney Diseases,National Institutes of Health, seeks an outstandingcandidate (M.D. and/or Ph.D.) with at least 4 yearspost-doctoral experience to participate in studieson cell biology of signal transduction by v-ERB-Arelated receptors. This is a position in aninnovative group with interests in basic and clinicalresearch. Applicant should have broad familiaritywith normal and abnormal human medicalphysiology. Preference will be given to acandidate with hands-on experience witheukaryotic tissue culture, radioligand assays ofsteroids and cyclic nucleotides, immunocytology,video microscopy, computerized image-processing(preferably UNIX-based systems), HPLCseparation, and molecular biology. Should beexperienced with use of microcomputer andmainframe computer system, includingapplications for statistics and graphics. Thecandidate should have experience in directingother post-doctoral scientists and in formulatingand carrying out original research, proven by asubstantial record of original publications incritically reviewed jourrals. Starting salary is$41,500 or may be negotiable commensurate withqualifications and background. Interested personsshould send their curriculum vitae, severalreprints, statement of goals, and names of threereferences to:

Dr. Stephen Marx '06 /L /q5Bldg. 10, Room 9C101 QNational Institutes of Health9000 Rockville PikeBethesda, MD 20892 9PEtVFor further information telephone Dr. Marx at(301) 496-5052.

NIH IS AN EQUAL OPPORTUNITY EMPLOYER

POSITIONS OPEN

POSITIONS OPEN

POSTDOCTORAL ASSOCIATEA challenging postdoctoral position is available to

study the molecular biology and regulation of geneexpression in yeast [Progr. Nudeic Acid Res. Mol. Biol. 37,284 (1989)]. We seek a motivated individual who canwork independently. Experience with cloning, sequenc-ing, DNA footprinting, mutagenesis, PCR, and proteinchemistry is desirable. Ph.D. in biochemistry or molecu-lar biology required. The position is available immediate-ly and salary is determined by NIH guidelines. Sendcurriculum vitae, a statement of research experience, abibliography, and names, addresses, and telephone num-bers of three references to: Dr. Julius Marmur or Dr.Paul Sollitti, Albert Einstein Collegc of Medicine,Department ofBiochemistry, 1300 Morris Park Avc-nue, Bronx, NY 10461. Telephone: 212-430-3024 or212430-2080. Affirmative Action/Equal Opportunity Em-ployer.

MOLECULAR BIOLOGIST/PROTEIN CHEMIST

CALIFORNIA INSTITUTE OFTECHNOLOGY

POSTDOCTORAL POSITION in protein engin-eering/protein chemistry. Design of novd protein cata-lrsts. Experience in protein characterization and Ph.D. inchemistry or biochemistry preferred. Send curriculumvitae and names of three references to: Dr. F. Arnold,Chemistry and Chemical Engneer', 210,41, Cali-fornia Institute ofTechnology, Pasadena, CA 91125.Caltech ia an Affirmative Action/Equal Opportunity Employer.Women and minorities are encouraged to apply.

POSTDOCTORAL POSMONS IN CELLU-LARANDMOLECULARNUTRMON. Two posi-tions are available to study the regulation of folate andone carbon metabolism. Projects include cloning, expres-sion, and site-directed mutagenesis of genes tor folate-dependent enxzymes; studies on the mecfianism of cataly-sis and substrate binding of folate enzymes; and studieson the regulation of folate and antifolate metabolism incultured mammalian cells. Ph.D. degree or equivalent inbiochemistry, nutrition, or related field, and experiencein recombinant DNA, protein chemistry, enzymology,and/or tissue culture techniques advantageous.Send curriculum vitae and names and addresses of

three references to: Dr. Barry Shane, Department ofNutritional Sciences, University of California, 329Morgan Hall, Berkdey, CA 94720. Telephone: 415-642-0750. An Affinnative Action/Equal OpportunityEmployer.

University of California, Irvine (UCI), POSTDOC-TORAL POSITIONS are available immediately tostudy the molecular biology of the epidermal growthfactor receptor in pancreatic cancer and signal transduc-tion mechanisms triggered by cytokines. Candidatesmust have recently obtained a Ph.D. or equivalent andshould have a strong background in molecular biology,gene doning, and/or signal transduction. Please sendcurriculum vitae and names and addresses of three refer-ences to: Dr. Murray Korc, Departments ofMedicineand Biochemistry, C-240, Med Sci I, University ofCalifornia, Irvine, CA 92717. UCI is an Equal Opportu-nity/Afirmative Action Employer.

NEUROBEHAVIORAL POSTDOCTORALPOSMONS

The positions are available for an interdisciplinaryneuropsychobiological research training program. Theprogram objectives are to facilitate the development ofmvestigators who are familiar with the integrated con-cepts of neuropsychobiology as well as their individualanatomical, biochemical, physiological, or clinical re-search specialties. Rapidly developing technological areasthat relate to the nervous system are periodically incorpo-rated into the program; for example, molecular genetics,neuropsychoimmunology, CNS virology (includingAIDS), and in vivo metabolic imaging. In addition to theintensive research experience in one or more laboratorydisciplines, the conceptual basis of neurosciences as itrelates to an understanding of the normal and maladapt-ive development ofhuman neurobiology and behavior isemphasized in seminars.

or a catalog of opprnties and application forms,contact: Dr. Everett W. Ellinwood, Duke UniversityMedical Center, Box 3870, Durham, NC 27710.Duke University is an Equal Opportunity/Afirmative ActionEmployer.

POSTDOCTORAL POSMONS. One to studycellular/molecular biology of nerve regeneration and oneto study mechanismns of synaptic plasticities (presynapticinhibition, long-term potentiation) via intracellular pene-trations of identified nerve terminals. Send curriculumvitae and three letters of reference to: Dr. George D.Bittner, Professor of Zoology, The University ofTexas, Austin, TX 78712. Telephone: 512-471-5454.FAX: 512-471-9651. An Equal Opportunity/AffirmativeAction Employer.

POSTDOCTORAL POSMONSOne position will be in the area of bacterial chemotaxis

and motility. Another position will be in the area ofregulation of expression of flagella and chemotaxis genes.Experience in biochemistry and/or molecular genetics isdesirable. One position is available in spring 1990 andthe second position will be available in fall 1990. Sendcurriculum vitae and names of three references to: Dr.Philip Matsumura, Laboratory ofMolecular Biolog,University of Illinois at Chicago, P.O. Box 4348,m/c-067, Chicago IL 60680. An Equal OpportunityEmployer.

POSTDOCTORAL. A position is available to workon the pathogenesis of human papillomaviruses (HPV)in cervical cancer; in particular, to investigate the role ofHPV genes in the immortalization and inhibition ofdifferentiation of human epithelial cells. Skills in tissueculture, DNA doning, site-directed mutagenesis, orRNA analysis would be an advantage. Please send curric-ulum vitae and names ofthree references to: Dr. DennisJ. McCance, Departmnent ofMicrobiology and Immu-nology, University of Rochester, 601 Elmwood Ave-nue, Box 672, Rochester, NY 14642. The University ofRochester is an Affirmative Acion/Equal OpportunityEmployer.

POSTDOCTORAL POSMON. To study the mo-lecular biology of plant mitochondria substrate trans-porters. Experience in the determination or modeling ofprotein structures, membrane biochemistry, and/or mo-lecular biology desired. Available for 3 years with a salaryto $25,000 per year plus benefits. Send curriculum vitaeand three references to: Dr. David J. Oliver, Depart-ment of Biochemistry, University of Idaho, Moscow,ID 83843.

POSTDOCTORAL POSMON, PHYCOLOGY.Available 1 July 1990, for 1 year, renewable for a secondyear. Applicants should have a strong background inphycology with emphasis in aquatic ecology/water quali-ty or cell biology/physiology. Experience in laboratoryculture of micro- and macroalgae desired. Review ofapplications will begin 1 March 1990 and continue at 7-day intervals until appointment is made. Send curriculumvitae, statement ofresearch interests, and three referencesto: Milton R. Sommerfeld, Department of Botany,Arizona State University, Tempe, AZ 85287-1601.Equal Opportunity/Affirmative Action Employer.

POSTDOCTORAL POSITIONAvailable July 1990 for an NIH-funded study on gene

regulation durng sea urchin development. Applicantswith Ph.D. shourd have experience in molecular biologyand preferably in embryology as well. Salary is commen-surate with experience. Send curriculum vitae and namesof three references to: Dr. Francesco Ramirez, Box1128A, Department of Molecular Biology, TheMount Sinai Medical Center, One Gustavc L. LevyPlace, New York, NY 10029-6574. An Equal Opportu-nity Employer.

POSTDOCTORAL POSITIONPosition available for an individual with a Ph.D. and

experience in molecular biology. The successful applicantwllbe engaged in research on the biochemical andmolecular mechanisms by which angiotensin peptidesand other hormonal and pharmacological stimuli medi-ate cardiac muscle cell growth. There will also be theopportunity to engage in research defining the role of alocalized intracardiac renin-angiotensin system in medi-ating cardiac muscle cell growth, with an emphasis on thereguation of the precursor genes for this system. Com-petitive salary and fringe benefits are available. Pleasesend curriculum vitae and three names or letters ofreference to: Dr. Kenneth M. Baker, Weis Center forResearch, Geisinger Clinic, Danville, PA 17822. EqualOpportunity Employer.

POSTDOCTORAL POSITIONMOLECULAR EVOLUTIONARY GENETICSAvailable to examine aspects of gene and genome

evolution in microorganisms and eukaryotes. Please sendcurriculum vitae to: Howard Ochiman, Department ofGcnetics, Box 8232, Washington University Schoolof Medicine, St. Louis, MO 63110. Tclephone: 314-362-2728. Equal Opportunity/Afirmative Action Employer,M/F/H/V.

POSTDOCTORAL POSITION. Wanted: one re-cent Ph.D. with research experience in molecular phylo-genetic techniques, and one with experience in teratologyor exercise physiology. Funded for 2 years. Begin May1990. For details, write: Postdoc, Department ofZool-ogy, Brigham Young University, Provo, UT 84602.

SYLVESTER COMPREHENSIVECANCER CENTER

UNIVERSITY OF MIAMISCHOOL OF MEDICINE

POSTDOCTORAL ASSOCIATEPosition available for a postdoctoral associate with a

Ph.D. degree in biochemistry or biochemical pharmacol-ogy. Individual should have experience in enzyme assays,tssue culture, nucleosides, biochemistry, HPLC, andother bioanalytical techniques. Send curriculum vitaewith names ofthree references to: Susan Martin, Assist-ant Director for Administration, Sylvester Compre-hensive Cancer Center, University of Miami, P.O.Box (016960) (R-71), Miami, FL 33101. AffirmativeAction/Equal Opportunity Employer.

POSTDOCTORAL POSMIION. We have a posi-tion open in the Division of Urology, University ofPennsylvania School of Medicine. The successful candi-date will study the molecular properties and pharmacolo-gy of potassium and calcium channel modulators invascular and non-vascular smooth muscles. Experiencewith tracer flux measurement technicues is required.Although this is an academic position within the Univer-sity ofPennsylvania, the research will be conducted in thelaboratory of a nearby pharmaceutical company. Thesalary range for this unique academic-pharmaccuticalpostdoctoral position is $25,000 to $34,000. Funds areavailable for relocation. All interested individuals shouldsend their r6sume and the names and addresses of threereferences to: Dr. Robert M. Levin, Director of BasicResearch, Division of Urology, University of Penn-sylvania Hospital, 3006 Ravdin Courtyard, 3400Spruce Street, Philadelphia, PA 19104.

POSTDOCTORAL POSITION in plant physiolo-gy to study the joint effects of air pollutants and c imaticstresses on photosynthesis and other physiological pro-cesses. Qualifications include Ph.D. in plant physiologyor related field and experience relevant to the researchtopic. Position is available now for a rninimum of2 years.Salary negotiable, commensurate with experience. Sendcurriculumn vitae and names ofthree references to: Dr. D.C. MacLean, Boyce Thompson Institute, TowerRoad, Ithaca, NY 14853. Boyce Thompson Institute is anAfirmative Action/Equal Opportunity Employer.

POSTDOCTORAL POSITION. Available imme-diately, to study molecular regulation of liver collagenand cytokine gene expression utilizing in vivo modelsand liver cell isolation and culture techniques. Experiencein cell and/or molecular biology desirable. Send curricu-lum vitae and names of three references to: Dr. BernardH. Davis, Department ofMedicine, Box 400, Univer-sity of Chicago Medical Center, 5841 South Mary-land Avenue, Chicago, IL 60637. Telephone: 312-702-1467.

POSTDOCTORAL POSITION IN MOLECU-LAR BIOLOGY. Available immediately to study theexpression of genes controlling mevalonate metabolismin rat liver. Experience in standard molecular biologytechniques required. Send curriculum vitae and names ofthree references by 1 March 1990 to: Dr. R. KennedyKeller, University of South Florida Collcge of Medi-cine, Department of Biochemistry and MolecularBiology, 12901 Bruce B. Downs Boulevard, MDCBox 7, Tampa, FL 33612-4799. The University ofSouth Florida is an Affirmative Action/Equal OpportunityEmployer.

SCIENCE, VOL. 247596

POSITIONS OPEN POSITIONS OPEN

Al.90op-

RESEARCH SCIENTISTAMMALLIN

EXPRESSION SYSTEMSAmgen is a recognized leader in the discovery and devel-opment of human pharmaceutical and diagnostic prod-ucts through applied biotechnology. Our continuedgrowth has created an immediate need for a ResearchScientist in our diagnostics group in Boulder, Colorado.

Candidates for this position must have a Ph.D. in anappropriate discipline and greater than 2 years' experi-ence in cloning and expression of proteins in mammalianexpression systems, development of mammalian expres-sion vectors, and host cell culturing and development. Astrong background in cell biology is highly desirable.

Amgen offers an excellent compensation and benefitspackage as well as the unique opportunity to contribute tosignificant research programs on the leading edge ofbiotechnology. If you have the necessary skills andqualifications and would like to be a part of a company thatplaces a high priority on its human resources, please senda resume or C.V., in confidence, to:

AMGEN BOULDER, INC.Personnel Dept.2045 32nd StreetBoulderCO 80301EqualOpportunityEmployer

FACULTY POSITIONASSOCIATE DEAN

FOR STUDENTS AND INSTRUCTION

The University of Florida, College of Veterinary Medicine invites applica-tions and nominations for a tenure/tenure track position with full-timeadministrative activity as an Associate Dean. Letters of applicationshould include a curriculum vitae outlining academic training, teachingand administrative experience and present professional activities. Alsorequested is a list of publications, a statement of professional goals andthe names of three or more persons who can provide letters of reference.Salary will be commensurate with training, experience and academicrank of the successful applicant.The mission of the College is to provide excellent teaching, research,service and extension programs based on current and future strengths ofits faculty and staff. The College has identified a series of areas,including creation of a more flexible curriculum, through a strategicplanning process, that it intends to spend considerable time implement-ing in the immediate future. The successful applicant will be expected toplay a key role in catalyzing those efforts. In addition to addressingpotential changes in the professional curriculum, the College will alsoemphasize expansion of graduate and post-professional programs. Asone of six colleges in the University's Health Sciences Center, forcollaborative programs in many aspects of biomedical research. TheCollege's affiliation with the University's Institute for Food and Agricultur-al Sciences also places it in a strong position for the full development offood animal, wildlife, equine, zoological, aquatic animal and relatedprograms. The College's semi tropical location also provides uniqueopportunities for it to develop strong programs in tropical medicine.Qualifications for the position include a DVM degree with advanceddegrees (MS and/or Ph.D) or a Ph.D in higher education administrationor similar field. Candidates with either terminal degree must have hadeducational and managerial experience in a veterinary college or otherhealth related professional colleges.Other qualifications include demonstrated administrative skills, a com-mitment to excellence in professional education and a teaching meth-ods. Applicatnts or nominees should be eligible for appointment to therank of Associate Professor or Full Professor. A detailed positiondescription is available upon request. Application deadline is March 15,1990. Position VM-8908. Dr. Ronald Gronwall, Search Committee,Chairperson, College of Veterinary Medicine, University of Florida, BoxJ-125, JHMHSC, Gainesville, FL 32610-0125. The University of Floridais an Equal Opportunity/Affirmative Action Employer.

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SCIENCE MAGAZINENEW LAB SERVICE DEPT.1515 BROADWAYNEW YORK, N.Y. 10036

PELTIDE CHEMISTm offmann-La Roche, one of the world's fore-

most pharmaceutical companies, is seekinga Senior Scientist-Peptide Chemist to con-

tribute to our efforts to ensure a healthier tomorrow.You will be responsible for peptide synthesis using

classical and solid phase technologies; and purification in-cluding HPLC and characterization of biologically relevantpeptides. Qualifications include a PhD in Organic,Bioorganic or Medicinal Chemistry (or a related field); 1-2years of postdoctoral experience preferred. A thoroughknowledge of both solution and solid phase synthesis ofpeptides, and experience in the purification andcharacterization of peptides are essential. Experience withstructure-activity relationships and a working knowledge ofconformational aspects of peptides are required to assist inthe design of biologically active peptides. Knowledge ofpeptide mimetics is highly desirable.

We offer a comprehensive compensation packageincluding an extremely generous benefits program. Forconsideration, please send your resume with present salary(those without this information wil not be acknowledged),to: Mrs. Eleanor M. Malone, Senior Professional StaffingSpecialist, Department AF, Hoffmann-La Roche Inc.,Nutley, New Jersey 07110. We are an equal opportunityemployer

Q Hoffmann-La RocheWorking Today For A Healthier Tomorrow

(A

POSITIONS OPEN

Advanced POSTDOCTORAL POSMIION for anindividual with interests in integrating contemporarybiophysics with current techniques in molecular biology/protein expression for the microbial polymerization ofbiologically relevant repeating peptide sequences.Recombinant DNA techniques have been utilized toconstruct a synthetic elastin polypentamer gene suitablefor expression in prokaryotic systems designed for highyield production. Please have resume and references sentto: Dr. Dan W. Urry, Director, Laboratory ofMolec-ular Biophysics, The University of Alabama at Bir-mingham, P.O. Box 300/Umversity Station, Bir-mingham, AL 35294. Telephone: 205-934-4177 or -4178. An Equal Opportunity/Affirmative Action Employer.

CENTER FOR INSECT SCIENCETHE UNIVERSITY OF ARIZONA

POSTDOCTORAL ANDGRADUATE STUDENT POSMONS

The Center for Insect Science is a multi-campus inter-disciplinary research program funded by the NationalScience Foundation (Biological Centers Award), theMacArthur Foundation (Vector Biology) and the Du-Pont and Monsanto Corporations. Participants includeover 50 research laboratories in the Departments ofBiochemistry, Ecology and Evolutionary Biology, Ento-mology, Molecular and Cellular Biology, Neurobiology,Pharmaceutical Sciences, and Veterinary Sciences at theUniversity of Arizona in Tucson, the Carl Hayden BeeResearch Center in Tucson, and the Zoology Depart-ment at Arizona State University in Tempe.

In addition to a stipend, postdoctoraf and graudatestudents receive funds to support research and are expect-ed to develop independent, collaborative projects. We areespecially interested in projects involving molecular andphysiological studies of msect vectors of parasites. Poten-tial applicants should contact: Dr. Henry Hagedorn,Director, Center for Insect Science, 430 ForbesBuilding, University of Arizona, Tucson, AZ 85721.The deadline for applications is 1 March 1990. Applica-tions from women and minority groups are encouraged. TheUniversity ofArizona is an Affirmative Acion/Equal Opportu-nity Employer.POSTDOCTORAL POSMON. Available July of

1990 to study (i) in vivo, pulmonary deposition/clear-ance of inhaled particles and (ii) in vitro particle dissolu-tion in lung lavage cells. Candidates should have experi-ence in at feast two of the following areas: the produc-tion/characterization of aerosols, in vitro techniq,ues fordeterminig solubility of particles in cells, and m vivoparticle inhalatio techniques to measure deposition/clear-ance of aerosols. Experience in use of radioisotopesdesired. Doctoral or equivalent degree in any associatedfield will be considerecf. To apply, send curriculum vitaeand three references by 1 Aprnl 1990 to: Dr. William D.Bennett, Center for Environmental Medicine andLung Biology, CB #7310, Medical Research Build-ingC, University ofNorth Carolina, Chapel Hill,NC27599. Affirmative Action/Equal Opportunity Employer.POSTDOCTORAL RESEARCH ASSOCIATE.

A position is available immediately to study the regula-tion of phospholipid metabolism and its relationship tosignal transduction and the cell cycle. Candidates with aPh.D. degree should submit their curriculum vitae, re-prints, and names of three references to: Dr. Charles 0.Rock, St. Jude Children's Research Hospital, 332North Lauderdale, Memphis, TN 38101. An EqualOpportunity/Afirmative-Action Employer.RESEARCH ASSOCIATE OR ASSISTANT RE-

SEARCH SCIENTIST to aid in landscape level spatialsimulation modeling of coastal systms7Skils and experi-ence in ecological modeling, remote sensing, and GIS aredesired along with the abdity to work in an interdisci-plinary group. Minimum requirement is a Ph.D. Salary iscommensurate with qualifications. Send a resume andnames of three references by 28 February 1990 to: Dr.Robert Costanza, Chesapeake Biological LaboratoryUniversity of Mrland (UM), Solomons, MD20688-0038. Telephone: 301-3264281. UM is anAffirmative Action/Equal Opportunity Employer.

POSTDOCTORAL POSMIION. A position isavailable for a recent Ph.D. or M.D. to investigate therole of retinoids in the immune response to bacterialantigens. In vivo and in vitro systems will be used toinvestigate regulation of antibody production and natu-ral killer cell function. Expenence in basic or clinicalimmunology, cellular and molecular biology, or nutri-tional biochemistry is required. Salary begins at $22,000per year, depending on experience. Please send curricu-lum vitae, a letter d7escribing experience and professionalgoals, and names of three referees to: Dr. A. CatharineRoss, Professor of Biochemistry, Deprtment ofPhysiology and Biochetry, Medical Coilege ofPennsylvania, 3300 Henry Avenue, Philadelphia, PA19129. An Equal Opportunity Employer.

CARNEGIE MELLON. POSTDOCTORAL RE-SEARCH appointment to work on chemical engineer-ing issues related to chemical weapon conventions.Should have a solid base in chemistry and understandingin the design of chemical plants. Involves strong interac-tions with the chemical industry and the negotiationprocess towards a chemical weapon convention. Sendresume to: Benoit Morl, Engineerinc and PublicPolicy, Camegie Melion University, Pittsburg, PA15213.

UNIVERSITY OF PENNSYLVANIAPOSTDOCTORAL POSITION/RESEARCH SCIENTIST

The Department of Dermatology is offering an out-standing opportunity to investigate the immunomodula-tory effects ofnovel antineoplastic therapies. The Univer-sity of Pennsylvania is a leading center m the use ofnewimmunotherapies in the treatment of autoimmune dis-ease and cancer. Collaboration with other major universi-ty centers is currently ongoing. Studies would focus onthe correction of abnormal immunoregulation and theinduction of heightened antitumor immunity producedby these therapies. Previous experience in cellular immu-nology, immunochemistry, and Northern blotting neces-sary. Substantial interaction with senior scientists inmolecular biology, immunodermatology, and photobiol-ogy possible.

Salary negotiable and duration of appointment flexi-ble. Reply to:

Alain H. Rook, M.D.Department of Dermatology

Hospital of the University of Pennsylvania2 Maloney Building

36th and Spruce StreetsPhiladelphia, PA 19104

The University of Pennsylvania is an Equal Opportuni-ty/Affirmative Action Employer.

U.S. DEPARTMENT OF AGRICULTUREAGRICULTURAL RESEARCH SERVICE

(USDA/ARS)POSTDOCTORAL RESEARCH ASSOCIATE

position is available immediately to study the mecha-nisms and regulation of nitrogen transport and metabo-lism in developing maize kernels. Approaches includeenzymology, immunology, 14C and "5N (liquid and solidNMR) incorporation, and in vitro kernel and endospermtissue culture. Candidates must have received a Ph.D.within the past 3 years in plant physiology/biochemistryor related areas. Starting salary is $29,891 (GS-11) peryear and 3 years of funding is available. Send a resume,marked 9N034, and the names of three references to:Michael J. Muhitch, Seed Biosynthesis ResearchUnit, USDA/ARS, Northern Rcgional Research Ccn-ter, 1815 North University Street, Peoria, IL 61604.Telephone: 309-6854011 (ext. 368). The AgriculturalResearch Service is an Affirmative Action/Equal OpportunityEmployer.

POSTDOCTORAL RESEARCH ASSOCIATEGENE EXPRESSION

Position available to study the elements controllingglobin gene activity at the molecular level using expres-sion vectors. Candidates must have Ph.D. with experi-ence in recombinant DNA technolopy. Salary to$30,000. Send resume to: Dr. R. F. Rieder, Depart-ment of Medicine, State University of New YorkHealth Science Center At Brooklyn, 450 ClarksonAvenue, Box #20, Brooklyn, NY 11203. Equal Oppor-tunity/Affirmative Action Employer. DMC #CR0284.

POSTDOCTORAI'RESEARCH ASSOCIATEIN GENE EXPRESSION

The named position is available immediately or by thefail to study muscle gene expression in Drosophila. We arestudying promoter and splicing function of contractileprotein genes in transgenic flies and protein bindingstudies in in vitro cell-free systems. Applicants must havea Ph.D. and experience in recombinant DNA methods isdesirable. Starting salary is competitive. Send curriculumvitae and names of threc references to: Dr. Robert V.Storti, Deprtment of Biochemistry, University ofIllinois Colege of Medicine, 1853 West Polk Street,Chicago, IL 60612. The University ofIllinos is an Affinna-tive Action/Equal Opportunity Employer.POSTDOCTORAL AND GRADUATE RE-

SEARCH POSITIONS IN THEORETICAL BIOL-OGY. To work on problems in population geneticsinvolving the evolution of cooperation, recombination,and mating systems, available 1 May 1990 or after.Postdoctoral salary range: $17,000 to $25,000, depend-ing on experience, plus fringe benefit package. Graduatestudent salary range (half-time, fiscal year): $9,923 to$11,071. Send curriculum vitae, statement of researchinterests, and three letters ofreference by 16 March 1990to: Dr. Richard Michod, Department ofEcology andEvolutionary Biology, University ofArizona, Tucson,AZ 85721.

The University of Arizona is an Equal Opportunity!Afirmative Acion Employer.POSTDOCTORALIRESEARCH ASSOCIATEPosition available immediately in retroviral research

group (multiyear NIH funded). Training in molecularbiology desired. Candidate will participate in ongoingstudies aimed at the detection and characterization ofknown and unknown retroviruses. Faculty position pos-sible. Salary commensurate with level of experience.Forward letters of interest including complete curricu-lum vitae to: Bernard J. Poiesz, M.D., Head, Divisionof Hcmatology/Oncology, Department of Medicine,750 East Adams Street, Syracuse, NY 13210. AnAfirmative Action/Equal Opportunity Employer. Applica-tions will be accepted until the position is filled.RESEARCH ASSOCIATE POSITION, PENN-

SYLVANIA STATE UNIVERSITY: Position avail-able to study pituitary cell structure and function; prolac-tin and estrogen involvement in immune modulation.Candidate must have experience in ELISA, intracellularand cell surface immunofluorescence, bioassays, lympho-kine receptor assays, and gel electrophorosis. Ph.D. inimmunology and knowledge of endocrinology required.A minimum of 1 year of postdoctoral experience re-quired. Salary range: $22,000 to $26,000 per year.Standard university benefits package. To apply, sendcurriculum vitae and names of three references by 9March 1990 to: Dr. W. C. Hymer, 401 Althouse,Molecualar and Cell Biology, The Pennsylvania StateUniversity, University Park PA 16802. An AffirmativeAction/Equal Opportunity Employer. Women and minoritiesare encouraged to apply.

PHARMACOLOGY RESEARCH ASSOCIATE.Conduct research to identify and characterize the neuro-nal binding sites for potent toxins, such as botulinumtoxin and tetanus toxin. Ph.D. in pharmacology or M.D.plus 5 years of expenrence in receptor pharmacology.mxperence/research in: molecular pharmacology or blo-logical chemistry; handling toxins, isotopes, cells inculture and microorganisms; radiolabelling toxins andbinding experiments; receptor isolation and characteriza-tion. History ofscholarly publications. $32,000 per year;40 hours per week. Apply to: Dr. Lance Simpson,Thomas Jefferson University (JAH), 1020 LocustStreet, Philadelphia, PA 19107.

RESEARCH SCIENTIST/GENETICENGINEERING OF FLOWER COLOR

DNA Plant Technologies, Inc., is the world's largestindependent agribiotech company. Position is availablefor a Ph.D. molecular biologist in our floriculture re-search program.The objective of this exciting program includes the

manipulation of flower colors and other traits of impor-tance to the flower industry. Please send resume withthree re&frences to: DNA Plant Technologies, Inc.,Richard Jorgensen, Ph.D., Director of FloricultureResearch, 6701 San Pablo Avenue, Oakland, CA94608-1239. An Equal Opportunity Employer.

SCIENCE, VOL. 247598

POSITIONS OPEN POSITIONS OPEN

FACULTY POSITIONS INMUSCULOSKELETALDISEASES RESEARCHMAYO CLINIC SCOTTSDALE

MAYO FOUNDATION

Faculty positions are open for career investigators (M.D., Ph.D.,or comparable degree) in musculoskeletal diseases research atMayo Clinic Scottsdale. Candidates must be U.S. citizens or per-manent residents, and should have advanced training and expe-rience in basic sciences related to biology of bone, cartilage, mus-cle, or connective tissues. Pertinent research areas might includemembrane function, G-proteins, protein kinases andphosphorylation, peptide control of gene expression, or controlof cellular differentiation.

Laboratories are under construction at Mayo Clinic Scottsdale,and a long-term program of planned research development isunderway. Available in support of the research effort will be amplemodern research space and equipment, start-up and continu-ing support, and the entire research, educational, and clinicalresources of the Mayo Clinic, Mayo Medical School, Mayo Grad-uate School, and the Graduate School of Medicine.

Qualified candidates should submit detailed curriculum vitae,bibliographies, and names of three references to:

Hunter Heath Ill, M.D. maDirector for ResearchMayo Clinic Scottsdale

13400 E. Shea Blvd.Scottsdale, AZ 85259(Telephone 602-391-8004 or507-285-6515)

DEANCollege of Computer, Mathematical,

and Physical SciencesUNIVERSITY OF MARYLAND,

COLLEGE PARKApplications and nominations are invited for the position of Dean of the

College of Computer, Mathematical, and Physical Sciences at the Universityof Maryland, College Park campus. The Dean provides both academic andadministrative leadership for the College and reports directly to the ViceChancellor for Academic Affairs and Provost.

The College consists of the departments of Computer Science, Geology,Mathematics, Meteorology, and Physics and Astronomy, as well as theApplied Mathematics Program, the Center for Automation Research, theChemical Physics Program, the Institute for Physical Science and Technolo-gy, the Institute for Advanced Computer Studies, and the Laboratory forPlasma Research. The College employs 472 faculty members and approxi-mately 800 support personnel. Presently about 2300 undergraduate studentsand 800 graduate students are enrolled in degree programs within theCollege. In 1988-89, researchers in the College were awarded approximately$34 million in external grants and contracts. The state-supported budget wasabout $28 million.

A candidate should have an earned doctorate, be eligible for appointmentin a department of the College at the rank of Professor with tenure, havesuccessful experience as a teacher and a distinguished record of scholarlyresearch, and have demonstrated leadership ability and management skills.

Applications should include a curriculum vitae and the names andaddresses of at least four references. For best consideration, all applicationsshould be submitted before March 1, 1990 to:

Patrick F. CunniffOffice of Graduate Studie & Research

2125 Lee BuildingUniversity of Maryland

College Park, Maryland 20742

The University of Maryland is an equal opportunity, affirmative action employ-er. Women and minority candidates are encouraged to apply.

CLINICAL RESEARCHPHARMACOK[NETICIST

Genentech, Inc., a leader in the field ofbiotechnology, has animmediate opening for a scientist in the PharmacokineticSecdon ofour Safety Evaluation Division. This individual willinteractwith scientific personnel fiom all depaments oftheCompany and will partidpate in the development ofdinicalpharmakinetic strtgies and clinical study activities.

We require a Ph.D. in Pharnaceutics, Pharmacoldnetics orPharmcologcl Sciens with 2-4 years' preclinical and clinicalADME industrial eperience or a Pharm.D. with 3-5 yearsof clinical pamaokinetic experience and publications.Clinical pharmacokinetic fellowship and maaromoleculeADMEexrence preferreiGenentech, Inc. offers an excellent salary and benefits packagcoupled with the opportunity to make a sigificnt contributionto our orgnizatn. For consideration, please send your C.V. toHuman Reurces DepartnentJM, Genentech, Inc., 460 PointSan Bruno BML, South San Francisco, CA 94080. We activelysupport and promote affimadtve action and equal employmentopportunity. Women and minorities are encourged to apply.

(C OW

DNX is an advanced biotechnology company whose main focus is theuse of transgenics to develop enhanced biological systems for drugdiscovery, safety testing, and livestock improvement. DNX hasattained a position of leadership in the transgenics industry, enjoyingclose ties to academic and government laboratories as well asbusiness partnerships with world leaders in the pharmaceutical andlivestock industries.

MOLECULAR BIOLOGY - PRINCETON, NEW JERSEYAn opening is available in our new Molecular Biology Center inPrinceton, New Jersey for an expert in the physiological and geneticaspects of spermatogenesis. Applicants for this position should holdthe Ph.D. degree and have a record of relevant independent research.Experience in molecular genetics and gene expression would bebeneficial. In addition, positions are available for MS/BS levelscientists with experience in recombinant DNA technology andmolecular genetics. Applicants should send a curriculum vitae,description of research accomplishments and the names, addressesand telephone numbers of three references to: J. Eugene LeClerc,Ph.D., DNX, 303B College Road East, Princeton, NJ 08540.

ANIMAL BIOLOGY - ATHENS, OHIOIn our Animal Biology Research Center in Athens, Ohio, there areopenings for BS/MS level scientists experienced in mammalian genetransfer and microinjection technology. Please send a curriculumvitae and the names, addresses and telephone numbers of threereferences to: Carl Pinkert, Ph.D., DNX, One President Street,Athens, OH 45701.

POSITIONS OPEN

RESEARCH ASSOCIATEThe Department of Biochemistry announces the avail-

ability of a research associate position in the area ofmetaloprotein structure and function. Previous experi-ence in one of the following areas is desirable: purifica-tion and/or characterization of membrane-bound en-zymes, mitochondrial electron transport proteins, bio-physical techniques (especially epr). Interested individ-uals should send a complete resume, together with thenames of three people who are willing to provide refer-ences for the applicant.

All information should be sent immediately to: G.Palmer, Biochemistry Department, Rice University,P.O. Box 1892, Houston, TX 77251. Rice University isan Equal Opportunity Employer.

RESEARCH ASSOCIATE. Position available forstudies in developmental neuroendocrinology. Ph.D. inphysiology, pharmacology, molecular biology, or relateddiscipline required. Experience including cei culture andradioimmunoassay preferred. Competitive salary. Pleasesend resume and names of references to: ResearchAssociate Position, c/o Dr. L. Cuttler, Rainbow Ba-bies and Childrens Hospital, Room 790, Case West-ern Reserve University, 2101 Adelbert Road, Cleve-land, OH 44106.

RESEARCH ASSOCIATE, 40 hours per week, 8a.m. to 5 p.m., $36,000 per year. Must have a Ph.D. inphysics. Will perform research on the development ofoptical monitoring schemes in fabrication of submicro-meter holographic structures for use in integrated cir-cuits. Will perform research on the characterization ofmetal films deposited on integrated circuits. Also willperform research on the development ofa new alignmentscheme based on the technique of multiple-holographicexposure. Must have 2 years of experience in the joboffered. Submit r6sumes to: New Mexico Departmentof Labor, 501 Mountain Road, N.E., Albuquerque,NM 87102. CC#1001. Job Order #276215f.RESEARCH ASSOCIATE IN POLYMER RHE-

OLOGY. Responsible for: (i) examining structural-property relationships in thermoplastic elastomers (TPE)and liquid crystalline polymers (LCP); (ii) evaluating theprocessing window of TPEs and LCPs; (iii) designingnew molecular structure of TPEs; and (iv) testing me-chanical properties of TPEs and LCPs. Requirements:Ph.D. in polymer science or chemical engineering and 2years of experience in job offered or as a researchassociate or assistant in polymer science. Must havedemonstrated knowledge in chemical structure and rhe-ology and mechanical properties of TPEs and LCPs;demonstrated ability in designing new molecular struc-ture of TPEs; demonstrated expertise in polymer pro-cessing; demonstrated expertise in operating infraredspectrometer, gel permeation chromatograph, tensilemachine and rheometer, and differential scanning calo-rimeter. Monday to Friday, 9 a.m. to 5 p.m.; $25,000per year. Send two r6sumes to: MASS DET, SpecialPrograms Unit, CF Hurley Buildinp, 19 StanifordStreet, Boston, MA 02114, Attention: Job Order#00199.RESEARCH ASSOCIATE IN POLYMER SCI-

ENCE. Responsible for: (i) investing and developingthermoplastic elastomers (TPEs) as binders for ammuni-tion and propellants; (ii) designing new molecular struc-ture of TPEs; (iii) synthesis of TPEs and liquid crystal-line polymers (LCPs); (iv) testing liquid crystal proper-ties of LCPs; and (v) examining structural-propertyrelationship in TPEs and LCPs. Requirements: B.Sc. inpolymer science or chemical engineering and 6 years ofexperience in job offered or 6 years of experience as aresearcher or professor of polymer science. Must have:demonstrated knowledge in organic synthesis, polymer-ization, and copolymerization; demonstrated knowledgein chemical structure and property of TPEs and LCPs;demonstrated expertise inorganic synthesis and polymer-ization; demonstrate expertise in separation and purifica-tion of monomers and polymers; demonstrate ability inoperating infrared spectrometer, thin-layer chromato-graph, nuclear megnatic resonance, gel permeation chro-matograph, vavoup pressure osmometer, differentialscanning calorimeter, and thermogravimetric analyzer;demonstrated expertise in polymer science as evidencedby published research. Forty hours per week, 9 a.m. to 5p.m. $25,000 per year. Send two resumes only to:MASS DET, Special Programs Unit, CF HurleyBuilding, 19 Staniford Street, Boston, MA 02114,Attention: Job Order #00213.

RESEARCH SCIENTIST. To perform scientificresearch, design, implement, oversee, and direct experi-ments to develop high-performance liquid chromatogra-phy (HPLC), enzyme-linked enzyme immunoassays(EIAs), or radioimmunoassay (RIA) as suitable alterna-tives to replace bioassay procedures used for stabilityindicating potency predication of salmon calcitonin-formulated products. Ph.D. in chemistry plus 1 year asassociate research chemist required. Previous experiencemust include 1 year of hands-on experience performingchemical research utilizing HPLC (reverse phase, size-exclusion, ion exchange afnity column), immunoassays(antibody production, purification, analyte modificationand conjugation, development of rapid flow injectionsandwich and competitive enzyme immunoassays, radio-immunoassays), ion-selective electrodes, and develop-ment offlow-through polymeric membrane ion selectiveelectrodes. Forty hours per week, 8:00 a.m. to 4:30 p.m.,Monday to Friday; $35,700 per year. Please send re-sumes to: L. Stewart, Manager of Personnel, Depart-ment 90R-JIJIN, Rorer Central Research, 640 Al-lendale Drive, King of Prussia, PA 19406. EqualOpportunity Employer.

VASCULAR RESEARCHAkron City Hospital is recruiting an independent

investigator with expertise in the cell and molecularbiology of vascular cells. Successful applicants would beexpected to establish an independent research program intheir field of specific interest as well as collaborative tieswith existing Faboratories involved in diverse aspects ofvascular research. Candidates should have a Ph.D. orM.D. with appropriate postdoctoral experience. Physi-cian-scientists are encouraged to apply.Akron City Hospital is a major teaching hospital for

the Northeastern Ohio Universities College of Medicine(NEOUCOM) with a strong commitment to clinical andapplied biomedical research. A competitive salary andfringe benefit package is available. Academic appoint-ments may be availa6le through NEOUCOM, the Uni-versity of Akron, and/or Kent State University. Sendcurriculum vitae, statement of research interests, salary/equipment/space requirements, and the names of at leastthree references to: Steven P. Schmidt, Ph.D., VascularResearch Laboratory, Akron City Hospital, 525 EastMarket Street, Akron, OH 44309.

Akron City Hospital is an Affirmative Action/Equal Oppor-tunity Employer.SILVICULTURE POSITION: Department ofFor-

estry and Natural Resources, Purdue Umversity. AS-SISTANT PROFESSOR, tenure-track. Twelve-monthappointment divided between research (70%) and teach-ing (30%). Research activities directed toward quantita-tive analysis of natural and human-induced environmen-tal, particularly climatic change on forest productivityand biodiversity. Teaching actsvities include teaching anundergraduate silviculture course and developing andteaching a graduate silviculture course. Applicant musthave a Ph.D. degree in forestry, forest ecology, silvicul-ture, or a closely related field and have extensive graduatetraining in silviculture. Applications accepted through 30April 1990 or until a satisfactory candidate is identified.For fur-ther information contact: Dr. Phillip E. Pope,Chair, Search Committee, Department of Forestryand Natural Resources, urd University, WestLafayette, IN 47907. Telephone: 317-494-3590. Pur-due University is an Equal Opportunity/Affirmative ActionEmployer.

SUPERVISORY METEOROLOGIST OR SU-PERVISORY PHYSICAL SCIENTIST, GM-14.Salary: $50,342. Department of Commnerce, Air Re-sources Laboratory, Atmospheric Sciences Modeling Di-vision, Research Triangle Park, North Carolina. Objec-tive is to initiate, supervise, and conduct research in airquality modeling to attain and define a detailed under-standing of the atmospheric and chemical processesaffecting the structure of the planetary boundary layerand the dispersion of air pollutants on all spatial andtemporal scales. Represents the government at scientificmeetings and seminars as an expert in the field of airpollution modeling. A college degree in meteorology orphysical science is required plus three years of profession-al experience of which 1 year is equivalent to the GS-13level in federal service. Related semester hours andprofessional experience may be subsituted for full collegedegree. U.S. citizenship is required. For information,cal: Ms. Beedie, telephone: 804 441-6548. The De-partment of Commerce is an Equal Opportunity Employer.

RESEARCH ASSISTANT, full-time, to operate andmaintain an Applied Biosystem 475 Protein Sequencer,431 Peptide Synthesizer, and Beckman System GoldAmino Acid Analyzer. B.S./M.S. required with experi-ence in protein sequencing, peptide synthesis, and/oramino acid analysis preferred. Send letter of interest,curriculum vitae, and three letters of references to: Dr.Russel Meints, Center for Gene Research and Bio-technology, Oregon State University (OSU), Corval-lis, OR 97331-2906. Telephone: 503-737-3413. Ap-plication closing date is 1 March 1990. Starting date is 1April 1990. OSU is an Affirmative Action/Equal Opportuni-ty Employer and complies with Seaion 504 ofthe RehabilitationAct of 1973. OSU has a policy ofbeing responsive to the needsofdual-career couples.SENIOR PRINCIPAL BIOMEDICAL ENGI-

NEER. Coordinate renal therapy research focusing onthe conception, construction, and clinical testing ofworking prototypes which demonstrate the feasibility ofmonitoring blood pressure and blood volume duringhemodialysis procedure in order to prevent symptomatichypotension; assume responsibility for on-line monitor-ing and signal processing of mammalian cardiovascularresponses including blood pressure, blood velocity, andblood density; direct, design, and fabrication of electricalcircuits and prototypes; prepare reports on cardiovascu-lar monitoring, control, and expert systems. Eight yearsof college, Ph.D. in electrical engineering; must haveM.S. degree in biomedical engineering; graduate levelcoursework must include at least one course in each ofthe following areas: artificial intelligence and robotics;fizzy sets/expert systems; adaptive and nonlinear con-trol; human physiological systems. Graduate level re-search work must include research in area ofcardiovascu-lar monitoring, control, and expert systems. Forty hoursper week; 9:00 a.m. to 5:00 p.m.; $47,500 per year.Send resumes to: Illinois Job Service, 401 South

State Street, 3 South, Chicago, IL 60605. Attention:Mary Millea. Reference #99'81-M. An employer-paid ad.

FELLOWSHIPS

POSTDOCTORAL FELLOWSHIPS for M.D.'sor Ph.D.'s to study the molecular genetics and pathogen-esis of neurodegenerative disorders, especially Alzheimer's disease. Preference given to individuals withbackground in molecular biology or protein chemistry.U.S. citizenship not required. Reply with curriculumvitae and names of references to: Drs. E. A. Schon or J.Herbert, Department of Neurology, College of Physi-cians of Columbia Univcrsity, 630 West 168th Street,New York, NY 10032. Columbia University is an EqualOpportunity Employer.

STAFF FELLOW POSTDOCTORALPOSITIONS AVAILABLE

IN BEHAVIORAL PHARMACOLOGYThe NIDA Addiction Research Center is the intramu-

ral research program of the National Institute on DrugAbuse. Staff felowship positions are available in thePreclinical Pharmacology Branch that involve research inthe behavioral pharmacology of drugs of abuse. Currentresearch projects are directed at, but are not limited to,stimulants, opioids, and benzodiazepines. Duties includeconducting experiments, supervising technical staff, andwriting manuscripts and reports. A Ph.D. is required,preferably in pharmacology or the experimental analysisof behavior. Candidates should be able to contributeintellectually to a broad-based program of research in thebehavioral pharmacology of drugs of abuse. Experiencewith intravenous drug self-administration and/or drugdiscrimination procedures, computers, and primates isdesirable but not essential. Salary ranges from $24,000to $43,345 depending on experience. The NIDA Addic-tion Research Center is an Equal Opportunity Employer andspecifically invites and encourages applications from women,minorities, and the handicapped.

If interested, please send a copy of your curriculumvitae to either:

Jonathan L. Katz, Ph.D. orSteven R. Goldberg, Ph.D.

NIDA Addiction Research CenterPreclinical Pharmacology Branch

P.O. Box 5180Baltimore, MD 21224

The Alcohol, Drug Abuse, and Mental Health Adminis-tration is an Equal Opportunity Employer. ADAMHA issmoke-free.

SCIENCE, VOL. 247600

POSITIONS OPEN POSITIONS OPEN

FELLOWSHIPS

POSTDOCTORAL FELLOWSHIPSIN THE DEPARTMENT OF ANATOMY

AND NEUROBIOLOGYUNIVERSITY OF CALIFORNIA, IRVINESeveral positions for research in individual laboratories

in the department are available for candidates who havedemonstrated research promise at the predoctoral orpostdoctoral level. The emphasis of research in thedepartment is in the neurosciences with special expertisein neuromorphology, sensory physiology, and molecularneurobiology. The faculty of the department and theirresearch interests are:Dr. Robert Blanks: Eye movement control, physiolo-

gy of upper airway.Dr. James Fallon: Chemical neuroanatomy, transmit-

ters, and growth factors.Dr. Christine Gall: Limbic/olfactory anatomy, neuro-

peptides, neurochemical plasticity.Dr. Roland Giolli: Visuomotor system.Dr. Stewart Hendry: Primate visual system.Dr. Paul Isackson: Molecular neurobiology.Dr. Edward Jones: Sensory-motor anatomy and

physiology.Dr. Glenn Kageyama: Oxidative metabolic develop-

ment and plastcity.Dr. Leonard Kitzes: Auditory system anatomy and

physiology.Dr. Sandra Loughlin: Monamines, peptides, and

growth factors and their receptors.Dr. Diane O'Dowd: Function and regulation of ion

channels in Drosophila.Dr. Charles Ribak: Epilepsy, neurotransmitters, and

circuits.Dr. Richard Robertson: Thalamocortical develop-

ment.Dr. Malcolm Semple: Auditory processing.Dr. Martin Smith: Cellular and molecular aspects of

synaptogenesis.Dr. John Swett: Spinal cord and peripheral nervous

system.Dr. Yasuhiro Torigoe: Peripheral nervous system and

oculomotor control.Applications or inquiries for additional information

should be sent to:Dr. Edward Jones, Professor and ChairmanDepartment ofAnatomy and Neurobiology

University of California, IrvineMed Surge II, Room 364

Irvine, CA 92717An Affirmative Action/Equal Opportunity Employer.

RESEARCH STAFF FELLOW or SENIORSTAFF FELLOW. Position available now to investi-gate genetic variation and molecular mechanisms con-trolling expression of genes involved in serotoninergicneurotransmission. Salary range: $24,000 to $52,825,depending upon qualifications and experience. Appli-cants should have a Ph.D. or M.D. and training inmolecular biology, recombinant DNA technology, orneurobiology. Send curriculum vitae and three referencesor letters of reference to: Dr. David Goldman, Sectionon Genetic Studies, Laboratory on Clinical Studies,National Institute on Alcohol Abuse and Alcoholism(NIAAA), Building 10, Room 3C103, 9000 Rock-vile Pike, Bethesda, MD 20892.

NIAAA is an Equal Opportunity Employer.POSTDOCTORAL FELLOWSHIP

RENAL CELL PHYSIOLOGY/BIOCHEMISTRYSeveral postdoctoral positions are available in a multi-

disciplinary hypertension program project, "VasoactiveHormones: Receptor and Signaling Mechanisms,"which indudes the Departments ofMedicine, Physiologyand Biophysics, Pharmacology, Genetics, and Environ-mental Health Sciences. Primary focus is on cell cultureof primary and transformed renal epithelial cells, regula-tion of transport in cell monolayers, and biochemistry ofintracellular signaling pathways. The positions providetraining opportunities m cell culture, transformation ofcells, epitheial electrolyte transport, biochemistry of P-450 enzymes, molecular biology, and video- and com-puter-enhanced light microscopy. Interested personsshould send curriculum vitae and two letters of recom-mendation to: Ulrich Hopfer, M.D., Ph.D., Depart-ment of Physiology and Biophysics, Case WesternReserve University (CWRU) School of Medicine,2119 Abington Road, Cleveland, OH 44106. Tele-phone: 216-368-2878. CWRU is an Equal OpportunityEmployer.

2 FEBRUARY 1990

POSTDOCTORAL FELLOW. Position availablefor an NIH-funded project to elucidate functions of thesteroid hormone 1,25-dihydroxyvitamin D in new tar-gets. Tissues/cells emphasized are heart, testis, and lung.Prior experience in biochemical endocrinology, tissueculture, and/or intracellular calcium homeostasis wouldbe helpful. Send curriculum vitae and three letters ofrecommendation to: Marian R. Walters, Ph.D., De-partment of Physiology, Tulane Medical School, NewOrlcans, LA 70112.

POSTDOCTORAL FELLOW. Research regula-tion of gene expression, specific focus on mammalianribosomal DNA genes; sequencing) subcloning, muta-genesis, and in vitro transcription. Ph.D. (or completionof all requirements for Ph.D. except defense of thesis) inmolecular biology or biochemistry. Six months of re-search experience in sequencing, subcloning, mutagene-sis, and in vitro transcription; 8:30 a.m. to 5:30 p.m.;$22,000 per year. Job Order Number: 4244902. Sendresumes to: Job Center, 941 West Arch Street, P.O.Box 548, Shamokin, PA 17872-0548.

POSTDOCTORAL FELLOWSHIPSIN NEW DRUG DEVELOPMENT

Pfizer Pharmaceuticals is offering fellowships in theareas ofmicrobiology, infectious diseases, pharmacology,pharmacokinetics, and toxicology, to provide trainingand management experience in the clinical and nonclini-cal development of anti-allergic, cardiovascular, CNS/analgesic, and anti-infective drugs. Two awards will begiven annually. Applicants must have a Ph.D., M.D., orPharm.D., and no more than 1 year of non-industrypostdoctoral experience as of 1 July 1990. The applica-tion deadline is 1 May 1990. For further information andapplication materials contact:

Fellowship Program in New Drug DevelopmentDepartment of Clinical and Scientific Affairs

Pfizer Pharmaceuticals235 East 42nd StreetNew York, NY 10017

Attention: Evan A. Stringer, Ph.D.Telephone: 212-573-7984

RESEARCH FELLOWA research fellow position starting June 1990 is avail-

able for 1 to 2 years in the field ofvascular physiologyand applied laser technology. Supervised independentlaboratory research availabe for M.D. or Ph.D. levelexperience. Salary range: $27,934 to $41,912. Applica-tions must be received no later than 30 April 1990.

Please forward resume, cover letter, and references to:Associate Director, Human Resources

Charlotte Memorial Hospital Medical CenterP.O. Box 32861

Charlotte, NC 28232Equal Opportunity Employer, MIF.

POSTDOCTORAL FELLOWSHIPSThe Science Alliance Center of Excellence invites

applications for two postdoctoral positions available inthe following areas: Chronic Virus Infection of theGastroenteric Tract-D. A. Brian, coronavirus; L. N. D.Potgieter, flavivirus; N. K. Clapp, marmoset research;Molecular Biology of Pathogenic Fungi-J. M. Becker,pheromones and transport; W. S. Riggsby, dimorphismand epidemiology; R. N. Moore, immunobiology; Mo-lecular Evolutionary Genetics-G. F. McCracken, DNAvariation in natural populations; potential collaborationwith C. R. B. Boake, A. C. Echternacht, D. A. Etnier, J.L. Gittleman, S. E. Riechert; Phytoplankton Ecology-W. 0. Smith; Immunobiology of Viral Infections-B. T.Rouse, herpesvirus; S. Kennel, antiviral immunity; Pro-tein Engineering-D. M. Roberts, calcium regulatoryproteins; E. Howell, dihydrofolate reductase; Metal Bio-chemistry-J. G. Joshi, ferritin; J. C. Churchich, pyri-doxal phosphate kinase; S. Georghiou, stopped-flowfluorometry; W. R. Farkas, metal toxicity; K. B. Jacob-son, metal toxicity. Interested individuals should writefor an application acket by 15 March 1990. Positionsare availa6le immeiately at a starting salary of $25,000per annum with the possibility of renewal. Write to:Science Alliance Postdoctoral Fellowship, BiologyConsortium, M303 Walters Life Science Building,The University of Tennessee, Knoxville, TN 37996.The University of Tennessee is an Equal Opportunity/Af-firnative Action/Title IX/Section 504 Employer.

POSTDOCIORAL FELLOWSHIPS INPRE-CUNICAL ANTI-CANCER RESEARCHDepartment of Molecular and Cellular BiologyThe Department of Molecular and Cellular Biology of Bristol-MyersSquibb Pharmaceutical Research and Development Division, currentlyhas positions available for postdoctoral fellows to study the regulatoryelements for growth factor gene expression or the mechanisms andregulation ofDNA replication. Qualified candidates will join an inter-disciplinary group working on growth factor gene regulation, autocrinegrowth factor production and the mechanisms of gene amplificationand drug resistance in human colon carcinoma cell lines.A Ph.D. in a relevant biological discipline and a strong background incellular and molecular biology or protein chemistry are required. Can-didates should demonstrate independent research skills and creativityas well as the ability to work well in a collaborative environment. Theappointments are or one year with an option for renewal at a highlycompetitive salary. The department maintains numerous academic col-laborations in our efforts toward basic anti-cancer research and noveldrug discovery; publication in peer reviewed scientific journals isstrongly encouraged.Please send resume to: BRISTOL-MYERS SQUIBB COMPANY,Pharmaceutical Research and Development Division, Attn: MH177,P.O. Box 5101, 5 Research Parkway, Wallingford, Cr 06492-7661. AnEqual Opportunity Employer M/F/H/V.

*ffi Bristol-Myers Squibb Company"Stronger Than Ever In Global Health Care"

FELLOWSHIPS FELLOWSHIPS

FELLOWSHIPS

ONCOLOGY RESEARCH FELLOWSHIPMEDICAL AND RADIATIONONCOLOGY RESEARCHSTARTING 1 JULY 1990

CLINICAL AND LABORATORY RESEARCHFELLOWS required to work in a multidisciplinarycancer center. Potential areas for clinical study includepain and symptom control, clinical pharmacology, clini-cal trials in breast cancer, molecular monitoring oflymphomas, immunotherapy, gynecologic malignancies,and other aspects of clinical epidemiology related tocancer. Laboratory research in the areas of immunology,

radiobiology, or molecular biology can be undertaken. A2-year commitment would be preferred, particularly inthe laboratory area, but 1-year posts will be considered.Please apply with curriculum vitae and three letters ofreference to:

Dr. Kathleen I. PritchardHead, Division of Medical Oncology

orDr. Alon J. Dembo

Head, Division of Radiation OncologyToronto-Bayview ReFional Cancer Centre

2075 Bayview AvenueToronto, Ontario, Canada M4N 3M5

SITUATIONS WANTED

CHEMIST, Ph.D. Solid credentials, 19 years. Seeksmoonlighting job in New York City/southern Connecti-cut area. Salary requirements very reasonable. Tele-phone: 919-929-3229.

GEOLOGIST, Ph.D. Six years of experience, radio-active waste; training in mechanics of detachment faults.Seeks entry-level hydrogeologist or mid-level geologistposition. Box 6, SCIENCE.

INFORMATION SCIENCE. Ph.D., medicinalchemistry. Background in spectroscopy, chromatogra-phy, synthesis, biochemistry. Library and teaching expe-ience. Familiar with on-line services. Carl P. Bergstrom,P.O. Box 417365, Chicago, IL 60641-7365.

NEUROSCIENTIST seeks career change. Ph.D.,M.S.; neurophysiology, 19 years. Skiliful writer, teacher,speaker to technical, legal, lay audiences. Interpersonaladroitness. Box 3, SCIENCE.

SEMI-RETIRED CHEMICAL ENGINEER.Seeks teaching post, or responsible charge of statisticalQC, model simulation, productivity enhancement, prof-itability analysis. P.O. Box 16925, San Diego, CA92116.

COURSES AND TRAINING

The Basic Science Departments (Cell Biology andNeuroanatomy, Biochemistry, Microbiology, Pathology,Pharmacology, Physiology), Medical School, Universityof Minnesota, periodically have openings for POST-DOCTORAL TRAINING.For information about possible openings in these

programs, write, specifying department of interest, to:

University of Minnesota Medical SchoolBox 293 UMHC

420 Delaware Street, S.E.Minneapolis, MN 55455

Attention: James C. NelsonThe University of Minnesota is an Equal Opportunity

Educator and Employer and specifically invites and encourages

applicationsfrom women and minorities.

Ph.D. TRAINING PROGRAM IN MOLECU-LARAND CELLULAR PHARMACOLOGY. Areasof research training include: Structure and function ofmembrane receptor and transporter proteins; platelet andvascular thromboxane and prostagiandin receptors; thetissue kallikrein-kinin system; hormonal and tissue con-trol of gene expression; mechanisms of arterial pressurecontrol; vascular endothelium; molecular toxicology;drug metabolism and pharmacokinetics. Graduate stu-dent stipends/fellowships up to $15,000 per year. Con-tact: Dr. George E. Lindenmayer, Department ofPharmacology and Experimcntal Therapeutics, Medi-cal University ofSouth Carolina, 171 Ashley Avenue,Charleston, SC 29425. An Equal Opportunity/AfirmativeAction Employer.

COURSES AND TRAINING

MEDICAL UNIVERSITY OF SOUTH CARO-LINA (MUSC) offers programs leading to Ph.D. andM.D./Ph.D. degrees in each of the basic biomedicalsciences (anatomy, biochemistry, microbiology/immuno-logy, pathology, pharmacology, physiology), biometry,pharmaceutical sciences, and molecular and cellular biol-ogy/medicine; $9000 assistantships available to qualifiedstudents. Contact: College of Graduate Studies,MUSC, 171 Ashley Avenue, Charleston, SC 29425.

CAREER CHANGE OPPORTUNITYThis unique program offers the candidate with an

earned doctorate in the sciences the opportunity toobtain the Doctor of Optometry (O.D.) degree in twocalendar years. Employment opportunities exist in pri-

vate practice, industry, education, and research. Contact:Dr. D. Chauncey, Program Director, AcceleratedProgram, The New Engand College of Optometry,Room S, 424 Beacon Street, Boston, MA 02115.

RESEARCH PROGRAMS FOR POSTGRADU-ATES, FACULTY, AND STUDENTS AT DE-PARTMENT OF HEALTH AND HUMAN SER-VICES laboratories including the Agency for ToxicSubstances and Disease Registry (Atlanta), Center forDevices and Radiological Health (Rockville, Maryland),and National Center for Toxicological Research (nearLittle Rock). U.S. citizenship or PRA status required. Forinformation (please indicate postgraduate, faculty, and/or student program), contact: Research ParticipationPrograms/DHHS, Attention: M. Mayton, Science/Engineering Education Division, Oak Ridge Associ-ated Universities, Box 117, Oak Ridge, TN 37831-0117. Telephone: 615-576-3190.

TRAINING PROGRAMIN CANCER BIOLOGY

AT WASHINGTON UNIVERSITYSCHOOL OF MEDICINEST. LOUIS, MISSOURI

Postdoctoral positions are available in a training pro-gram covering diverse cellular and molecular aspects ofcell biology. The program is eclectic and geared to thosewith an M.D. or Ph.D. in biological sciences. Traineesare expected to spend 2 to 3 years in the laboratory.The different laboratories are conducting research in

oncogenes, cellular immunology, growth factors, cyto-kines, molecular biology, T cell differentiation, generegulation, antigen processing and presentation, kinasesand phosphatases and their role m cell growth, andreceptor-mediated endocytosis.The training faculty includes: Dr. Paul M. Allen, Dr.

Jacques Baenziger, Dr. Thomas Braciale, Dr. ThomasDeuel, Dr. Stanley Korsmeyer, Dr. Dennis Loh, Dr.Jeffrey Milbrandt, Dr. Robert Schreiber, Dr. PhilipStahl, Dr. MatthewThomas, and Dr. Emil R. Unanue.For information, please directly contact any member

of the training faculty or Mrs. Charlotte Hanson,Washington niversity School of Medicine, Depart-ment ofPathology, St. Louis,MO 63110. Telephone:314-362-7440. Washington University is an Equal Oppor-tunity Employer. We are particularly interested in minorityapplicants.

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SCIENCE, VOL. 247

INTERNATIONAL MEETING

BIOINFORMATICS, INTEGRATIONOF ORGANISMIC AND MOLECULARDATA BASES, AND USE OF EXPERT

SYSTEMS IN BIOLOGY

July 9-11, 1990GEORGE MASON UNIVERSITY,

FAIRFAX, VIRGINIA, USA(Located 15 miles from Washington, DC)

The meeting will consist of invitedpapers, poster sessions, and work-shops to advance understanding,foster communication, and explorethe organization of a society dealingwith those fields of research thathave come to be summarized in theterm BIOMATRIX. Some travel sup-

port will be available for presenters.

For information write to:

Professor Harold Morowitz207 East BuildingGeorge Mason UniversityFairfax, VA 22030, USA

hmorewtz@gmuvax.bitnet. (NW4679)M

ELEANOR ROOSEVELT

1990 SOMATIC CELL ANDMOLECULAR GENETICS

LABORATORY WORKSHOPThe Eleanor Roosevelt Institute will again offer aSomatic Cell and Molecular Genetics Workshop,July 15-30, 1990. This NCI sponsored labora-tory course provides a combined somatic celland molecular biology workshop experience.The course has been designed to provide a"hands-on" introduction to the methodology andconcepts of current molecular biology proce-dures for scientists who need to exploit thesetechniques for their continuing research pro-grams. The content of this workshop also pro-vides the basic techniques needed for research-ers interested in initiating genome mapping stud-ies. Included in the curriculum are: somatic cellhybridization and mutant isolation, yeast molec-ular biology, isolation and analysis of DNA andRNA, preparation and in vitro translation ofpolyadenylated mRNA, DNA-mediated genetransfer, PCR, pulse-field gel electrophoresis,DNA sequencing, Western, Northern, andSouthern analyses, one and two-dimensionalgel electrophoresis, and the preparation andscreening of cDNA and genomic libraries. Princi-pal investigators whose research interests focuson malignancy are particularly invited to apply.No registration fees are charged and a per diemstipend is provided. Interested individuals shouldrequest an application form by postcard from:Lawrence A. Beck, Ph.D., Program Director,Somatic Cell and Molecular Genetics Work-shop, Eleanor Roosevelt Institute, 1899 Gay-lord Street, Denver, CO 80206.Completed applications must be received by

April 1, 1990. U.S. citizens orGreen Card holders only.L i

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