Porosity Response of Layer-by-Layer Nanocapsules on the Basis of Ultraviolet Light
description
Transcript of Porosity Response of Layer-by-Layer Nanocapsules on the Basis of Ultraviolet Light
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Porosity Response of Layer-by-Layer Nanocapsules on the Basis of Ultraviolet LightDavid HuangUniversity of Texas at AustinDepartment of Biomedical EngineeringDr. Frank Ji, Ph.D.
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Drug Delivery via NanocapsulesNanocapsule shell of polymer nanoparticles Held together by electrostatic forcesDrug kept inside until released
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Benefits of NanocapsulesReceptors can be added without change to drug structureMinimize drug degradationIncrease drug bioavailability Dosage for drugs can be decreased by 10,000 folds
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Controlling RateLooking for a method pulsatile releaseControlling Rate of Release of the Drug via light energyEnergized Bonds causes Conformational Change
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Demonstration of ConceptWould conformational change really cause a noticeable difference in rate of release?Ultraviolet Light (355 nm) used especially just for demonstrationDrug replaced by Fluorescein dye to be detected once releasedPolymer used: Poly[1-[4-(3-carboxy-4-hydroxyphenylazo)benzenesulfonamido]-1,2-ethanediyl, sodium salt](PHES)
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Plans to test ConceptCreate two samples of the nanocapsulesFill them with dyePlace them in two environmentsAbsence of lightUV emitterMeasure the rate of release of the dye
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Creating and Filling NanocapsulesHFHFSilica ParticlePEIPHESFluorescein
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Testing Phase
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Chart1
0000.818
0000.828
0000.8
0000.878
0000.906
0000.969
0001.027
0001.102
0001.227
0001.371
0001.51
0001.714
0001.946
0002.195
0002.468
000.0782.645
00.1250.2113.122
00.2540.3683.751
00.4370.5764.484
0.0070.5360.7995.328
0.0530.9321.116.193
0.1611.3461.4337.324
0.2541.8211.8358.49
0.4022.1992.3259.818
0.622.6272.95911.35
0.8753.0963.6813.08
1.1583.5964.51115.15
1.4984.2865.47117.4
1.9275.0186.61619.62
2.4175.858.04822
2.9866.8429.63824.74
3.6087.98811.4127.61
4.329.0513.530.57
5.17410.315.6933.55
5.9811.8118.0436.34
6.94113.3520.6739.36
8.04415.123.5342.18
9.12616.7526.6745.15
10.3618.4629.9347.76
11.6720.2733.250.45
12.921.9136.5652.56
14.1423.5239.8654.81
15.3325.4943.157.3
16.6227.3146.1759.21
17.6528.9248.5660.65
18.6930.5651.2761.74
19.6732.1253.6462.84
20.3933.2555.2563.75
20.8933.56757.0764.47
21.434.26758.2364.66
21.7534.67859.0664.73
21.9435.12659.4464.64
22.0535.6159.7764.63
22.0535.23659.5564.26
22.135.159.1963.98
21.8334.12658.7263.3
21.633.6257.7762.65
21.233.29656.361.78
20.7932.0555.1461.24
20.2631.6553.5960.47
19.6831.1951.9659.53
19.1330.8350.6658.56
18.4730.1949.1357.43
17.9829.5647.3856.58
17.3728.7745.5355.85
16.6727.944.0754.98
15.9826.9242.2554.1
15.3326.0240.4953.08
14.6725.0638.8852.35
13.9924.0837.2751.58
13.423.1935.7650.88
12.7822.1434.3950.05
12.2121.2533.1549.41
11.7220.4131.948.74
11.1219.6230.5548.2
10.6418.7329.3847.69
10.2317.9228.3147.34
9.82317.1627.446.77
9.44216.4726.3346.31
9.06315.8125.4545.7
8.7915.1224.6245.21
8.5214.5223.8444.68
8.19214.0223.0544
7.90613.3722.3743.58
7.62812.8821.7542.97
7.35712.3821.0342.34
7.19511.9820.4841.67
7.03911.5519.9440.89
6.81311.1419.2340.2
6.67310.7618.6839.44
6.42310.4718.0938.73
6.1399.96217.5237.7
5.869.55916.9536.83
5.6359.35416.4335.92
5.4549.08215.6735.11
5.2428.75215.0534.12
5.0438.46814.4833.07
4.7758.19913.932.24
4.5747.88413.3531.31
4.317.54112.7830.3
4.1417.17312.1629.25
3.9446.89511.6128.11
3.7426.61711.0327.09
3.5246.35810.5326.29
3.3256.069.96525.12
3.1175.7399.36923.99
2.8975.3978.78822.8
2.7155.1778.31721.85
2.5324.8937.8520.87
2.3674.6257.37319.94
2.2214.3186.9119.01
2.054.0646.54918
1.8623.8586.13417.12
1.7343.5745.71516.32
1.5993.2935.3215.58
1.4763.0265.04614.86
1.3522.8674.70814.03
1.2212.6644.39613.33
1.0792.4484.01912.63
0.9772.2793.71611.95
0.9042.0943.47611.3
0.841.9133.24710.69
0.7571.7173.04110.18
0.7061.612.8279.662
0.6181.4762.6049.247
0.5441.3852.4348.864
0.4941.2352.2848.4
0.4221.1452.1178.044
0.4011.0391.9977.604
0.3480.961.8457.284
0.3130.8661.6936.943
0.2550.7661.5566.601
0.1930.6961.466.326
0.1630.6451.3776.104
0.1520.6231.2955.8
0.1060.5481.2285.48
0.0760.481.1525.22
0.0470.4141.0674.975
0.0230.3810.9814.708
0.0090.3080.8954.529
0.0020.2750.8164.281
Intensity after 5 min
Intensity after 10 min
Intensity after 15 min
Intensity after 20 min
Wavelength (nm)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules Energized by UV Light
Chart2
000.2360.8180.952
000.2460.8281.24
000.2510.81.235
000.2440.8781.643
000.2690.8951.782
00.1340.3120.9691.709
00.2450.3510.9951.923
00.2780.3871.1022.352
00.3460.461.2272.63
00.480.5521.3712.873
00.9340.6561.512.832
01.1450.791.7142.965
01.2580.9211.9462.987
01.451.1232.1953.012
01.3781.3742.4683.784
01.4561.6632.8583.926
01.6681.9753.3494.324
01.7682.4353.8544.567
01.8352.8854.4745.432
0.0712.5463.355.1785.632
0.2132.7683.9956.0826.125
0.3562.8754.7537.0497.432
0.522.9875.6268.2028.346
0.7453.0116.4828.5549.231
1.014.5637.6189.8489.658
1.3594.6788.7411.313.235
1.8024.8799.94613.0415.57
2.3285.32611.4814.8515.687
2.9386.43213.1516.9318.325
3.6167.45614.941919.543
4.5129.45316.620.8921.1
5.45710.23418.4321.421.25
6.53112.47520.3522.5423.54
7.69714.57222.2623.4325.71
8.93715.567224.125.4327.87
10.3517.28325.9926.32530.17
11.9218.567827.8629.4532.41
13.5820.23529.7931.2334.6
15.3122.47331.6833.25636.92
17.224.83833.2335.1238.85
18.9426.478334.5935.67840.51
20.7628.5436.137.12542.2
22.3632.56737.2639.2543.55
24.2633.567238.5440.2344.79
25.834.562739.5941.68545.82
27.2835.67840.1542.3846.76
28.4436.12540.7542.987447.51
29.5136.83741.2643.78548.04
30.2537.1241.5943.97548.53
31.0437.98741.8844.1548.69
31.4338.01242.0244.3248.91
31.9138.3742.0144.4348.63
32.138.12541.944.6148.21
32.0537.987741.7544.2348.02
31.6537.45241.2843.76547.72
31.1936.89540.9142.96247.44
30.8335.5640.6142.56346.66
30.1934.675340.0542.1246.07
29.5633.98739.4241.65745.38
28.7732.85438.7440.49844.66
27.932.36438.1640.21543.95
26.9231.59637.6939.25843.19
26.0231.27437.0739.142.53
25.0630.48636.4238.4341.68
24.0829.9835.8337.8441.1
23.1929.12535.2437.2140.53
22.1428.45834.5436.5439.96
21.2528.12534.0436.239.1
20.4127.68533.3335.4238.52
19.6227.12533.0735.2138.2
18.7326.98432.634.7537.62
17.9226.34132.2934.5636.97
17.1625.87431.8533.4536.43
16.4724.9331.2733.2536.04
15.8124.5130.8432.8435.69
15.1224.0130.5232.5135.52
14.5223.630.1532.1535.02
14.0223.1629.8431.8434.55
13.3722.7329.5731.5434.3
12.8822.2329.2431.2533.96
12.3821.8728.9730.9533.39
11.9821.4128.530.5432.97
11.5520.8128.1430.1232.6
11.1420.1827.5829.56732.08
10.7620.4127.2229.2231.74
10.4719.6226.7928.7531.17
9.96218.6226.6328.6330.43
9.55917.8226.0728.0130.05
9.35417.0925.4627.4629.57
9.08216.4824.9726.9728.9
8.75215.8424.3726.4728.2
8.46815.1823.825.76527.67
8.19914.5223.2524.78626.99
7.88413.922.824.59826.38
7.54113.3122.2324.37225.85
7.17312.5621.6223.15625.12
6.89511.8821.0722.67824.18
6.61711.2920.5522.57323.4
6.35810.6519.7622.12422.72
6.0610.2319.2321.54322.02
5.7399.82318.6221.34621.2
5.3979.44217.8220.78420.55
5.1779.06317.0919.56219.78
4.8938.7916.4819.25618.9
4.6258.5215.8418.54618.28
4.3188.19215.1817.25917.43
4.0647.90614.5216.12616.63
3.8587.62813.915.32515.85
3.5747.35713.3114.87515.19
3.2937.19512.5614.2115.01
3.0267.03911.8813.25814.285
2.8676.81311.2912.45213.483
2.6646.67310.6511.25312.235
2.4486.42310.110.87511.857
2.2796.1399.60210.25411.251
2.0945.869.17310.12910.98
1.9135.6358.6619.87410.583
1.7175.4548.2789.25110.125
1.615.2427.8438.9859.93
1.4765.0437.4158.1259.231
1.3854.7757.0427.9238.893
1.2354.5746.6567.258.251
1.1454.316.3026.8437.832
1.0394.1416.0356.5827.351
0.963.9445.7646.5216.982
0.8663.7425.4516.2016.238
0.7663.5245.1165.9836.018
0.6963.3254.8095.6215.716
0.6453.1174.5935.215.448
0.6232.8974.4764.8295.146
0.5482.7154.2654.6724.947
0.482.5324.0274.3254.733
0.4142.3673.8284.2154.429
0.3812.2213.6214.1854.239
0.3082.053.4783.8274.039
0.2751.8623.3363.7213.886
0.2511.7343.1423.6123.695
0.2081.5992.9943.3153.467
0.1711.4762.8473.2713.312
0.1361.3522.7083.1853.148
0.0921.2212.5342.853.01
Intensity after 5 min
Intensity after 10 min
Intensity after 15 min
Intensity after 20 min
Intensity after 25 min
Wavelength (nm)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules in the Absence of Light
Chart3
32.122.1
38.3735.61
42.0259.77
44.6164.73
48.9164.23
45.3263.32
39.1458.72
26.8755.28
26.2147.68
26.0827.63
Nanocapsules under the absence of light
Nanocapsules energized by UV light
Time (min)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules over Time
Chart4
32.122.1
38.3735.61
42.0259.77
44.6164.73
48.9120
In the Absence of Light
Energized by UV Light
Time (min)
Fluorescent Intensity
Increasing Fluorescent Intensity Released by Nanocapsules over Time
Sheet1
DK1UV1TimePeaks
Data PointsData PointsDKUVDKUV
nmDataDataDataDataDataDataDatanmDataDataDataDataDataData032.122.122.9824.12
460000.2360.8180.9520.8530.3715.4575.1644.6854600000.8180.8010.7940.3610.3510.3710.236538.3735.6126.6929.31
461000.2460.8281.240.9340.3995.3595.1614.4894610000.8280.8670.8120.3790.3670.3990.2461042.0259.7727.729.6
462000.2510.81.2350.9520.3554.7494.7284.0284620000.80.8430.8250.3930.3870.3550.2511544.6164.7329.632.19
463000.2440.8781.6431.1560.3564.0224.0453.4224630000.8780.8310.8340.4260.4150.3560.2442048.9164.2330.447.75
464000.2690.8951.7821.2560.3553.4083.3822.8714640000.9060.8920.8660.4820.4260.3550.2692545.3263.3234.640.32
46500.1340.3120.9691.7091.3560.3532.8632.8432.3854650000.9690.9350.9120.570.4860.3530.3123039.1458.7227.833.21
46600.2450.3510.9951.9231.5720.3762.4882.4582.074660001.0270.9750.9430.6690.5830.3760.3516026.8755.2823.6227.67
46700.2780.3871.1022.3521.6920.4282.3222.2241.9224670001.1021.0480.9650.7580.7230.4280.38712026.2147.6820.4524.68
46800.3460.461.2272.631.9280.4972.2242.1151.8714680001.2271.1531.2560.8540.7930.4970.4624026.0827.6319.2319.16
46900.480.5521.3712.8732.0510.5522.1692.0791.8944690001.3711.2251.3460.9860.8950.5520.552
47000.9340.6561.512.8322.1560.6182.1081.9951.8444700001.511.361.8671.1591.0450.6180.656
47101.1450.791.7142.9652.2560.7412.0511.9731.7634710001.7141.511.6731.3521.2450.7410.79
47201.2580.9211.9462.9872.4160.8652.061.9281.7994720001.9461.7541.6921.5681.3560.8650.921
47301.451.1232.1953.0122.7121.0432.1281.9781.8734730002.1951.9761.8761.8441.5861.0431.123
47401.3781.3742.4683.7842.8361.2432.1532.0131.9574740002.4682.2472.1252.2391.6791.2431.374032.122.1
47501.4561.6632.8583.9263.2361.5342.1972.0552.012475000.0782.6452.6332.5462.8582.5981.5341.663538.3735.61
47601.6681.9753.3494.3243.5671.8212.2812.1222.12347600.1250.2113.1223.2363.1253.3493.0631.8211.9751042.0259.77
47701.7682.4353.8544.5673.6322.1992.4762.3162.2947700.2540.3683.7513.5673.2353.8543.5612.1992.4351544.6164.73
47801.8352.8854.4745.4323.7352.6272.6762.5222.50947800.4370.5764.4844.3264.1294.4744.0962.6272.8852048.91
4790.0712.5463.355.1785.6324.2163.0962.9322.7392.7754790.0070.5360.7995.3285.2314.685.1784.7343.0963.5625
4800.2132.7683.9956.0826.1254.4563.5963.2943.1043.1974800.0530.9321.116.1936.2375.436.0825.4693.5963.96
4810.3562.8754.7537.0497.4325.2364.2863.7643.5273.6584810.1611.3461.4337.3247.2126.977.0496.4194.2864.097
4820.522.9875.6268.2028.3465.6325.0184.2563.9844.174820.2541.8211.8358.498.3627.348.2027.4375.0184.526
4830.7453.0116.4828.5549.2316.3255.854.7694.5414.7164830.4022.1992.3259.8189.7238.459.4458.5545.855.141
4841.014.5637.6189.8489.6586.8926.8425.3765.1525.3934840.622.6272.95911.3510.3269.23410.839.8486.8425.728
4851.3594.6788.7411.313.2358.3467.9886.1025.8166.1224850.8753.0963.6813.0811.23510.2312.3911.37.7626.394
4861.8024.8799.94613.0415.579.2369.056.8126.5346.9054861.1583.5964.51115.1515.23614.2314.1813.048.6687.16
4872.3285.32611.4814.8515.68710.23610.37.6057.3597.7624871.4984.2865.47117.416.23615.23616.2214.8511.428.014
4882.9386.43213.1516.9318.32512.36211.818.4748.3118.6684881.9275.0186.61619.6218.23616.2318.2816.9313.258.936
4893.6167.45614.941919.54315.23613.359.4429.2199.6284892.4175.858.0482221.2520.4320.531915.949.855
4904.5129.45316.620.8921.115.89215.110.5110.2810.734902.9866.8429.63824.7424.53623.6522.8521.0818.35210.99
4915.45710.23418.4321.421.2518.32616.7511.5911.3611.914913.6087.98811.4127.6126.23525.3425.4823.2519.5412.18
4926.53112.47520.3522.5423.5421.23618.4612.8112.5913.124924.329.0513.530.5729.12628.5628.0225.8121.5313.35
4937.69714.57222.2623.4325.7121.32620.2713.9813.7714.244935.17410.315.6933.5531.23630.6530.728.3524.3514.6
4948.93715.567224.125.4327.8722.56121.9115.1314.8915.414945.9811.8118.0436.3432.36231.2533.3230.9128.43515.71
49510.3517.28325.9926.32530.1724.26123.5216.2515.9916.644956.94113.3520.6739.3635.235.6435.7733.2329.3216.95
49611.9218.567827.8629.4532.4125.98625.4917.4917.1517.764968.04415.123.5342.1839.12538.4538.4535.7731.2518.14
49713.5820.23529.7931.2334.627.89327.3118.5718.3319.064979.12616.7526.6745.1542.12541.2341.0338.2534.2519.24
49815.3122.47331.6833.25636.9230.2628.9219.619.4420.0749810.3618.4629.9347.7645.23642.6543.5340.5135.4220.35
49917.224.83833.2335.1238.8535.21630.5620.5720.4421.0849911.6720.2733.250.4549.23648.2345.7542.7236.3321.4
50018.9426.478334.5935.67840.5138.26132.1221.4321.2721.9850012.921.9136.5652.5651.2651.6747.9344.6437.122.33
50120.7628.5436.137.12542.240.63733.2522.3222.0422.9950114.1423.5239.8654.8153.23652.6849.846.5737.8423.27
50222.3632.56737.2639.2543.5540.98234.2923.2322.8323.7350215.3325.4943.157.358.43655.3251.7348.1838.3224.29
50324.2633.567238.5440.2344.7941.26935.4223.9723.6524.4650316.6227.3146.1759.2159.23656.5453.2349.8638.6525.02
50425.834.562739.5941.68545.8241.64836.3324.5724.1925.1350417.6528.9248.5660.6560.76558.7854.651.0741.9225.72
50527.2835.67840.1542.3846.7642.69437.125.1724.7125.6150518.6930.5651.2761.7461.32659.2355.8852.1742.5626.26
50628.4436.12540.7542.987447.5143.99737.8425.4525.0926.1650619.6732.1253.6462.8462.36560.3456.7753.0143.6726.66
50729.5136.83741.2643.78548.0444.02538.3225.6425.426.450720.3933.2555.2563.7563.67861.2457.3553.7844.5327.06
50830.2537.1241.5943.97548.5344.72138.6525.9525.8426.7250820.8933.56757.0764.4763.98661.4957.8754.3846.4327.25
50931.0437.98741.8844.1548.6945.02139.0426.1426.0826.8250921.434.26758.2364.6664.12562.4558.3354.7846.9827.43
51031.4338.01242.0244.3248.9145.3239.1426.8726.2126.8451021.7534.67859.0664.7364.21962.7858.4455.1847.2627.49
51131.9138.3742.0144.4348.6345.20639.1126.0326.126.0851121.9435.12659.4464.6464.2363.3258.6755.2847.6827.63
51232.138.12541.944.6148.2144.21638.9325.9925.9926.7651222.0535.6159.7764.6363.26162.3458.5655.1746.9427.66
51332.0537.987741.7544.2348.0243.65738.6126.0225.8826.751322.0535.23659.5564.2663.12962.1958.2654.845.6827.42
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51928.7732.85438.7440.49844.6640.87536.1324.3624.5125.0451920.2631.6553.5960.4759.23658.7554.4951.4741.125.9
52027.932.36438.1640.21543.9540.67235.4823.8223.9424.6152019.6831.1951.9659.5359.126658.2353.6750.6940.4625.53
52126.9231.59637.6939.25843.1940.51834.8323.3623.5824.4152119.1330.8350.6658.5658.32857.3452.9949.9139.5125.1
52226.0231.27437.0739.142.5339.7434.3123.0423.3123.8552218.4730.1949.1357.4357.65456.4652.0949.2638.3524.64
52325.0630.48636.4238.4341.6839.47133.8422.6722.8723.4452317.9829.5647.3856.5856.23856.2451.1948.4837.2624.18
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52820.4127.68533.3335.4238.5234.32831.2421.0621.3721.8452814.6725.0638.8852.3551.23651.9647.6344.8632.9622.4
52919.6227.12533.0735.2138.234.12830.7920.8821.0621.4852913.9924.0837.2751.5850.23649.2646.7644.1932.7522.17
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53117.9226.34132.2934.5636.9733.72630.0220.3620.4121.0453112.7822.1434.3950.0549.3248.1545.5242.9830.2721.51
53217.1625.87431.8533.4536.4333.46129.6620.0320.1820.8853212.2121.2533.1549.4148.9647.2344.8442.3730.4621.23
53316.4724.9331.2733.2536.0432.15629.1819.7719.9220.5753311.7220.4131.948.7448.1247.7844.4241.9329.5721.14
53415.8124.5130.8432.8435.6932.01228.7519.4819.7720.2853411.1219.6230.5548.247.1346.7843.9441.4129.3420.81
53515.1224.0130.5232.5135.5231.87628.4719.1919.5720.1353510.6418.7329.3847.6946.8946.2443.5340.9428.4520.55
53614.5223.630.1532.1535.0231.73228.1419.1119.2319.8453610.2317.9228.3147.3446.5745.6842.8840.628.1420.29
53714.0223.1629.8431.8434.5531.57227.6818.8518.9519.45379.82317.1627.446.7745.2145.3642.4940.227.5620.15
53813.3722.7329.5731.5434.330.57127.418.7518.7619.245389.44216.4726.3346.3145.1244.1241.8139.7527.4319.85
53912.8822.2329.2431.2533.9630.25127.0618.518.6619.155399.06315.8125.4545.744.6743.2641.3339.1426.5819.69
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54111.9821.4128.530.5432.9728.5626.3817.9318.2418.685418.5214.5223.8444.6843.1242.6740.5138.2425.3819.21
54211.5520.8128.1430.1232.628.45626.0817.7817.8718.475428.19214.0223.054442.6742.3639.9237.7525.118.94
54311.1420.1827.5829.56732.0827.34525.7417.5917.6218.235437.90613.3722.3743.5842.1241.6739.3237.2624.7318.6
54410.7620.4127.2229.2231.7427.12925.3317.3417.5117.935447.62812.8821.7542.9741.8641.2938.9436.6324.1618.38
54510.4719.6226.7928.7531.1726.89524.9317.0817.2917.75457.35712.3821.0342.3441.5640.2638.2936.0623.4718.19
5469.96218.6226.6328.6330.4326.78424.5116.781717.45467.19511.9820.4841.6740.6939.2637.6335.4922.4917.91
5479.55917.8226.0728.0130.0526.34624.0116.5916.6916.915477.03911.5519.9440.8939.1239.6837.0734.9421.5817.69
5489.35417.0925.4627.4629.5725.36823.616.2716.416.615486.81311.1419.2340.237.2338.2536.3934.4921.3817.26
5499.08216.4824.9726.9728.925.123.1615.9416.1116.425496.67310.7618.6839.4436.5435.2635.923420.1516.97
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5528.19914.5223.2524.78626.9924.21221.8714.9915.0115.285525.869.55916.9536.8335.2334.2633.3931.8328.5615.85
5537.88413.922.824.59826.3823.68121.4114.6614.715.045535.6359.35416.4335.9235.1234.2632.6130.9218.4515.5
5547.54113.3122.2324.37225.8522.98320.8114.2114.314.715545.4549.08215.6735.1134.2633.1631.6330.1418.2315.11
5557.17312.5621.6223.15625.1222.57620.1813.7613.9514.35555.2428.75215.0534.1234.1232.1731.0529.2817.9814.73
5566.89511.8821.0722.67824.1822.12919.6713.4113.5113.825565.0438.46814.4833.0733.6832.1930.1828.4817.4614.36
5576.61711.2920.5522.57323.421.68319.1412.9713.1213.45574.7758.19913.932.2433.5631.8529.2927.716.8413.89
5586.35810.6519.7622.12422.7221.36118.512.6412.6513.045584.5747.88413.3531.3132.4531.2728.4226.9816.3713.43
5596.0610.2319.2321.54322.0220.12617.8212.2512.3112.725594.317.54112.7830.331.2130.5827.5326.115.3713.07
5605.7399.82318.6221.34621.219.98217.1911.711.9312.35604.1417.17312.1629.2530.6730.2626.6525.2515.2612.72
5615.3979.44217.8220.78420.5519.57216.6311.2911.511.85613.9446.89511.6128.1128.4527.8725.5524.2214.9512.25
5625.1779.06317.0919.56219.7819.2115.9510.9111.0511.285623.7426.61711.0327.0928.1227.6324.5523.214.2511.71
5634.8938.7916.4819.25618.918.3215.3710.4810.5510.785633.5246.35810.5326.2927.65426.4723.5322.5513.5711.23
5644.6258.5215.8418.54618.2817.93614.79.93510.1910.45643.3256.069.96525.1226.4325.3722.6321.712.5710.83
5654.3188.19215.1817.25917.4317.26114.099.4819.7099.9635653.1175.7399.36923.9922.5421.8921.7220.8812.3910.43
5664.0647.90614.5216.12616.6316.113.499.0779.3319.4785662.8975.3978.78822.821.6820.9720.8219.9411.469.961
5673.8587.62813.915.32515.8515.4212.88.7548.9379.025672.7155.1778.31721.8520.12520.0519.819.0210.269.492
5683.5747.35713.3114.87515.1914.23512.268.4388.5518.6195682.5324.8937.8520.8719.4319.2619.0318.059.868.997
5693.2937.19512.5614.2115.0113.58611.698.0278.1258.3085692.3674.6257.37319.9419.3418.7818.1317.299.568.602
5703.0267.03911.8813.25814.28512.52411.097.5547.7237.8795702.2214.3186.9119.0118.6917.9617.2316.459.468.248
5712.8676.81311.2912.45213.48311.5910.517.2427.3847.4475712.054.0646.5491818.3217.3616.3815.718.957.873
5722.6646.67310.6511.25312.23511.419.9826.8716.9577.135721.8623.8586.13417.1217.3416.4915.5914.848.367.449
5732.4486.42310.110.87511.85710.2359.4976.5176.5696.8055731.7343.5745.71516.3217.2316.0214.7514.18.166.995
5742.2796.1399.60210.25411.2519.8569.036.1386.286.4975741.5993.2935.3215.5815.7815.2314.0713.527.346.727
5752.0945.869.17310.12910.989.5328.5525.8795.9936.1295751.4763.0265.04614.8615.2314.9613.412.867.146.405
5761.9135.6358.6619.87410.5839.1258.1515.585.6595.7865761.3522.8674.70814.0314.6813.4812.7512.16.976.061
5771.7175.4548.2789.25110.1258.7347.6795.2755.3395.4775771.2212.6644.39613.3313.2313.0412.1111.456.875.756
5781.615.2427.8438.9859.938.2317.3075.0045.1645.2245781.0792.4484.01912.6313.1212.9511.4210.896.7345.423
5791.4765.0437.4158.1259.2318.16.9124.7824.8524.9675790.9772.2793.71611.9510.2310.2810.8610.346.635.178
5801.3854.7757.0427.9238.8937.8566.6254.5694.6024.7085800.9042.0943.47611.310.110.0410.359.8926.454.904
5811.2354.5746.6567.258.2517.2356.2434.2734.3794.4375810.841.9133.24710.699.459.659.8399.3536.214.668
5821.1454.316.3026.8437.8326.8745.9444.0914.1034.1875820.7571.7173.04110.189.219.019.2718.8695.984.395
5831.0394.1416.0356.5827.3516.3475.6373.8163.9323.9255830.7061.612.8279.6628.658.688.8728.5045.864.212
5840.963.9445.7646.5216.9826.2365.3033.6633.7083.755840.6181.4762.6049.2478.238.678.5618.095.724.008
5850.8663.7425.4516.2016.2385.8655.0583.4673.5423.6025850.5441.3852.4348.8648.548.468.1597.7685.633.802
5860.7663.5245.1165.9836.0185.3464.7643.2813.3223.4095860.4941.2352.2848.47.237.947.7597.3785.123.601
5870.6963.3254.8095.6215.7165.1254.4953.1253.1583.2315870.4221.1452.1178.0447.547.457.3686.9784.823.415
5880.6453.1174.5935.215.4484.7454.3072.9953.0073.0615880.4011.0391.9977.6047.127.26.9886.6854.763.267
5890.6232.8974.4764.8295.1464.4774.1072.8322.8292.9395890.3480.961.8457.2847.646.976.6666.2944.653.075
5900.5482.7154.2654.6724.9474.1263.8952.7192.7452.7885900.3130.8661.6936.9436.436.876.3456.0524.522.905
5910.482.5324.0274.3254.7333.9823.6672.552.6652.6155910.2550.7661.5566.6016.126.496.0745.7854.422.778
5920.4142.3673.8284.2154.4293.5473.5152.3892.5372.4775920.1930.6961.466.3266.345.865.8155.494.322.635
5930.3812.2213.6214.1854.2393.4563.4062.2942.4042.3285930.1630.6451.3776.1045.985.365.5515.2523.972.521
5940.3082.053.4783.8274.0393.4213.2062.1862.2462.2235940.1520.6231.2955.85.765.2915.3315.0053.862.392
5950.2751.8623.3363.7213.8863.13.0252.1082.1662.1435950.1060.5481.2285.485.235.125.0574.7483.752.266
5960.2511.7343.1423.6123.6952.9152.8761.9752.042.0465960.0760.481.1525.224.764.964.8054.5333.692.177
5970.2081.5992.9943.3153.4672.8652.7411.8471.9041.9615970.0470.4141.0674.9754.654.764.5524.3193.572.042
5980.1711.4762.8473.2713.3122.7362.5631.7461.81.8325980.0230.3810.9814.7084.124.264.3144.0693.451.939
5990.1361.3522.7083.1853.1482.6352.4111.7031.6771.7285990.0090.3080.8954.5293.983.924.1173.8863.271.835
6000.0921.2212.5342.853.012.5192.3031.5821.6021.656000.0020.2750.8164.2813.763.653.8633.6792.851.775
Sheet2
Sheet3
-
Fluorescent Intensity Released by Nanocapsules Energized by UV Light
Chart1
0000.818
0000.828
0000.8
0000.878
0000.906
0000.969
0001.027
0001.102
0001.227
0001.371
0001.51
0001.714
0001.946
0002.195
0002.468
000.0782.645
00.1250.2113.122
00.2540.3683.751
00.4370.5764.484
0.0070.5360.7995.328
0.0530.9321.116.193
0.1611.3461.4337.324
0.2541.8211.8358.49
0.4022.1992.3259.818
0.622.6272.95911.35
0.8753.0963.6813.08
1.1583.5964.51115.15
1.4984.2865.47117.4
1.9275.0186.61619.62
2.4175.858.04822
2.9866.8429.63824.74
3.6087.98811.4127.61
4.329.0513.530.57
5.17410.315.6933.55
5.9811.8118.0436.34
6.94113.3520.6739.36
8.04415.123.5342.18
9.12616.7526.6745.15
10.3618.4629.9347.76
11.6720.2733.250.45
12.921.9136.5652.56
14.1423.5239.8654.81
15.3325.4943.157.3
16.6227.3146.1759.21
17.6528.9248.5660.65
18.6930.5651.2761.74
19.6732.1253.6462.84
20.3933.2555.2563.75
20.8933.56757.0764.47
21.434.26758.2364.66
21.7534.67859.0664.73
21.9435.12659.4464.64
22.0535.6159.7764.63
22.0535.23659.5564.26
22.135.159.1963.98
21.8334.12658.7263.3
21.633.6257.7762.65
21.233.29656.361.78
20.7932.0555.1461.24
20.2631.6553.5960.47
19.6831.1951.9659.53
19.1330.8350.6658.56
18.4730.1949.1357.43
17.9829.5647.3856.58
17.3728.7745.5355.85
16.6727.944.0754.98
15.9826.9242.2554.1
15.3326.0240.4953.08
14.6725.0638.8852.35
13.9924.0837.2751.58
13.423.1935.7650.88
12.7822.1434.3950.05
12.2121.2533.1549.41
11.7220.4131.948.74
11.1219.6230.5548.2
10.6418.7329.3847.69
10.2317.9228.3147.34
9.82317.1627.446.77
9.44216.4726.3346.31
9.06315.8125.4545.7
8.7915.1224.6245.21
8.5214.5223.8444.68
8.19214.0223.0544
7.90613.3722.3743.58
7.62812.8821.7542.97
7.35712.3821.0342.34
7.19511.9820.4841.67
7.03911.5519.9440.89
6.81311.1419.2340.2
6.67310.7618.6839.44
6.42310.4718.0938.73
6.1399.96217.5237.7
5.869.55916.9536.83
5.6359.35416.4335.92
5.4549.08215.6735.11
5.2428.75215.0534.12
5.0438.46814.4833.07
4.7758.19913.932.24
4.5747.88413.3531.31
4.317.54112.7830.3
4.1417.17312.1629.25
3.9446.89511.6128.11
3.7426.61711.0327.09
3.5246.35810.5326.29
3.3256.069.96525.12
3.1175.7399.36923.99
2.8975.3978.78822.8
2.7155.1778.31721.85
2.5324.8937.8520.87
2.3674.6257.37319.94
2.2214.3186.9119.01
2.054.0646.54918
1.8623.8586.13417.12
1.7343.5745.71516.32
1.5993.2935.3215.58
1.4763.0265.04614.86
1.3522.8674.70814.03
1.2212.6644.39613.33
1.0792.4484.01912.63
0.9772.2793.71611.95
0.9042.0943.47611.3
0.841.9133.24710.69
0.7571.7173.04110.18
0.7061.612.8279.662
0.6181.4762.6049.247
0.5441.3852.4348.864
0.4941.2352.2848.4
0.4221.1452.1178.044
0.4011.0391.9977.604
0.3480.961.8457.284
0.3130.8661.6936.943
0.2550.7661.5566.601
0.1930.6961.466.326
0.1630.6451.3776.104
0.1520.6231.2955.8
0.1060.5481.2285.48
0.0760.481.1525.22
0.0470.4141.0674.975
0.0230.3810.9814.708
0.0090.3080.8954.529
0.0020.2750.8164.281
Intensity after 5 min
Intensity after 10 min
Intensity after 15 min
Intensity after 20 min
Wavelength (nm)
Fluorescent Intensity
Chart2
000.2360.8180.952
000.2460.8281.24
000.2510.81.235
000.2440.8781.643
000.2690.8951.782
00.1340.3120.9691.709
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00.2780.3871.1022.352
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00.480.5521.3712.873
00.9340.6561.512.832
01.1450.791.7142.965
01.2580.9211.9462.987
01.451.1232.1953.012
01.3781.3742.4683.784
01.4561.6632.8583.926
01.6681.9753.3494.324
01.7682.4353.8544.567
01.8352.8854.4745.432
0.0712.5463.355.1785.632
0.2132.7683.9956.0826.125
0.3562.8754.7537.0497.432
0.522.9875.6268.2028.346
0.7453.0116.4828.5549.231
1.014.5637.6189.8489.658
1.3594.6788.7411.313.235
1.8024.8799.94613.0415.57
2.3285.32611.4814.8515.687
2.9386.43213.1516.9318.325
3.6167.45614.941919.543
4.5129.45316.620.8921.1
5.45710.23418.4321.421.25
6.53112.47520.3522.5423.54
7.69714.57222.2623.4325.71
8.93715.567224.125.4327.87
10.3517.28325.9926.32530.17
11.9218.567827.8629.4532.41
13.5820.23529.7931.2334.6
15.3122.47331.6833.25636.92
17.224.83833.2335.1238.85
18.9426.478334.5935.67840.51
20.7628.5436.137.12542.2
22.3632.56737.2639.2543.55
24.2633.567238.5440.2344.79
25.834.562739.5941.68545.82
27.2835.67840.1542.3846.76
28.4436.12540.7542.987447.51
29.5136.83741.2643.78548.04
30.2537.1241.5943.97548.53
31.0437.98741.8844.1548.69
31.4338.01242.0244.3248.91
31.9138.3742.0144.4348.63
32.138.12541.944.6148.21
32.0537.987741.7544.2348.02
31.6537.45241.2843.76547.72
31.1936.89540.9142.96247.44
30.8335.5640.6142.56346.66
30.1934.675340.0542.1246.07
29.5633.98739.4241.65745.38
28.7732.85438.7440.49844.66
27.932.36438.1640.21543.95
26.9231.59637.6939.25843.19
26.0231.27437.0739.142.53
25.0630.48636.4238.4341.68
24.0829.9835.8337.8441.1
23.1929.12535.2437.2140.53
22.1428.45834.5436.5439.96
21.2528.12534.0436.239.1
20.4127.68533.3335.4238.52
19.6227.12533.0735.2138.2
18.7326.98432.634.7537.62
17.9226.34132.2934.5636.97
17.1625.87431.8533.4536.43
16.4724.9331.2733.2536.04
15.8124.5130.8432.8435.69
15.1224.0130.5232.5135.52
14.5223.630.1532.1535.02
14.0223.1629.8431.8434.55
13.3722.7329.5731.5434.3
12.8822.2329.2431.2533.96
12.3821.8728.9730.9533.39
11.9821.4128.530.5432.97
11.5520.8128.1430.1232.6
11.1420.1827.5829.56732.08
10.7620.4127.2229.2231.74
10.4719.6226.7928.7531.17
9.96218.6226.6328.6330.43
9.55917.8226.0728.0130.05
9.35417.0925.4627.4629.57
9.08216.4824.9726.9728.9
8.75215.8424.3726.4728.2
8.46815.1823.825.76527.67
8.19914.5223.2524.78626.99
7.88413.922.824.59826.38
7.54113.3122.2324.37225.85
7.17312.5621.6223.15625.12
6.89511.8821.0722.67824.18
6.61711.2920.5522.57323.4
6.35810.6519.7622.12422.72
6.0610.2319.2321.54322.02
5.7399.82318.6221.34621.2
5.3979.44217.8220.78420.55
5.1779.06317.0919.56219.78
4.8938.7916.4819.25618.9
4.6258.5215.8418.54618.28
4.3188.19215.1817.25917.43
4.0647.90614.5216.12616.63
3.8587.62813.915.32515.85
3.5747.35713.3114.87515.19
3.2937.19512.5614.2115.01
3.0267.03911.8813.25814.285
2.8676.81311.2912.45213.483
2.6646.67310.6511.25312.235
2.4486.42310.110.87511.857
2.2796.1399.60210.25411.251
2.0945.869.17310.12910.98
1.9135.6358.6619.87410.583
1.7175.4548.2789.25110.125
1.615.2427.8438.9859.93
1.4765.0437.4158.1259.231
1.3854.7757.0427.9238.893
1.2354.5746.6567.258.251
1.1454.316.3026.8437.832
1.0394.1416.0356.5827.351
0.963.9445.7646.5216.982
0.8663.7425.4516.2016.238
0.7663.5245.1165.9836.018
0.6963.3254.8095.6215.716
0.6453.1174.5935.215.448
0.6232.8974.4764.8295.146
0.5482.7154.2654.6724.947
0.482.5324.0274.3254.733
0.4142.3673.8284.2154.429
0.3812.2213.6214.1854.239
0.3082.053.4783.8274.039
0.2751.8623.3363.7213.886
0.2511.7343.1423.6123.695
0.2081.5992.9943.3153.467
0.1711.4762.8473.2713.312
0.1361.3522.7083.1853.148
0.0921.2212.5342.853.01
Intensity after 5 min
Intensity after 10 min
Intensity after 15 min
Intensity after 20 min
Intensity after 25 min
Wavelength (nm)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules in the Absence of Light
Chart3
32.122.1
38.3735.61
42.0259.77
44.6164.73
48.9164.23
45.3263.32
39.1458.72
26.8755.28
26.2147.68
26.0827.63
Nanocapsules under the absence of light
Nanocapsules energized by UV light
Time (min)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules over Time
Chart4
32.122.1
38.3735.61
42.0259.77
44.6164.73
48.9120
In the Absence of Light
Energized by UV Light
Time (min)
Fluorescent Intensity
Increasing Fluorescent Intensity Released by Nanocapsules over Time
Sheet1
DK1UV1TimePeaks
Data PointsData PointsDKUVDKUV
nmDataDataDataDataDataDataDatanmDataDataDataDataDataData032.122.122.9824.12
460000.2360.8180.9520.8530.3715.4575.1644.6854600000.8180.8010.7940.3610.3510.3710.236538.3735.6126.6929.31
461000.2460.8281.240.9340.3995.3595.1614.4894610000.8280.8670.8120.3790.3670.3990.2461042.0259.7727.729.6
462000.2510.81.2350.9520.3554.7494.7284.0284620000.80.8430.8250.3930.3870.3550.2511544.6164.7329.632.19
463000.2440.8781.6431.1560.3564.0224.0453.4224630000.8780.8310.8340.4260.4150.3560.2442048.9164.2330.447.75
464000.2690.8951.7821.2560.3553.4083.3822.8714640000.9060.8920.8660.4820.4260.3550.2692545.3263.3234.640.32
46500.1340.3120.9691.7091.3560.3532.8632.8432.3854650000.9690.9350.9120.570.4860.3530.3123039.1458.7227.833.21
46600.2450.3510.9951.9231.5720.3762.4882.4582.074660001.0270.9750.9430.6690.5830.3760.3516026.8755.2823.6227.67
46700.2780.3871.1022.3521.6920.4282.3222.2241.9224670001.1021.0480.9650.7580.7230.4280.38712026.2147.6820.4524.68
46800.3460.461.2272.631.9280.4972.2242.1151.8714680001.2271.1531.2560.8540.7930.4970.4624026.0827.6319.2319.16
46900.480.5521.3712.8732.0510.5522.1692.0791.8944690001.3711.2251.3460.9860.8950.5520.552
47000.9340.6561.512.8322.1560.6182.1081.9951.8444700001.511.361.8671.1591.0450.6180.656
47101.1450.791.7142.9652.2560.7412.0511.9731.7634710001.7141.511.6731.3521.2450.7410.79
47201.2580.9211.9462.9872.4160.8652.061.9281.7994720001.9461.7541.6921.5681.3560.8650.921
47301.451.1232.1953.0122.7121.0432.1281.9781.8734730002.1951.9761.8761.8441.5861.0431.123
47401.3781.3742.4683.7842.8361.2432.1532.0131.9574740002.4682.2472.1252.2391.6791.2431.374032.122.1
47501.4561.6632.8583.9263.2361.5342.1972.0552.012475000.0782.6452.6332.5462.8582.5981.5341.663538.3735.61
47601.6681.9753.3494.3243.5671.8212.2812.1222.12347600.1250.2113.1223.2363.1253.3493.0631.8211.9751042.0259.77
47701.7682.4353.8544.5673.6322.1992.4762.3162.2947700.2540.3683.7513.5673.2353.8543.5612.1992.4351544.6164.73
47801.8352.8854.4745.4323.7352.6272.6762.5222.50947800.4370.5764.4844.3264.1294.4744.0962.6272.8852048.91
4790.0712.5463.355.1785.6324.2163.0962.9322.7392.7754790.0070.5360.7995.3285.2314.685.1784.7343.0963.5625
4800.2132.7683.9956.0826.1254.4563.5963.2943.1043.1974800.0530.9321.116.1936.2375.436.0825.4693.5963.96
4810.3562.8754.7537.0497.4325.2364.2863.7643.5273.6584810.1611.3461.4337.3247.2126.977.0496.4194.2864.097
4820.522.9875.6268.2028.3465.6325.0184.2563.9844.174820.2541.8211.8358.498.3627.348.2027.4375.0184.526
4830.7453.0116.4828.5549.2316.3255.854.7694.5414.7164830.4022.1992.3259.8189.7238.459.4458.5545.855.141
4841.014.5637.6189.8489.6586.8926.8425.3765.1525.3934840.622.6272.95911.3510.3269.23410.839.8486.8425.728
4851.3594.6788.7411.313.2358.3467.9886.1025.8166.1224850.8753.0963.6813.0811.23510.2312.3911.37.7626.394
4861.8024.8799.94613.0415.579.2369.056.8126.5346.9054861.1583.5964.51115.1515.23614.2314.1813.048.6687.16
4872.3285.32611.4814.8515.68710.23610.37.6057.3597.7624871.4984.2865.47117.416.23615.23616.2214.8511.428.014
4882.9386.43213.1516.9318.32512.36211.818.4748.3118.6684881.9275.0186.61619.6218.23616.2318.2816.9313.258.936
4893.6167.45614.941919.54315.23613.359.4429.2199.6284892.4175.858.0482221.2520.4320.531915.949.855
4904.5129.45316.620.8921.115.89215.110.5110.2810.734902.9866.8429.63824.7424.53623.6522.8521.0818.35210.99
4915.45710.23418.4321.421.2518.32616.7511.5911.3611.914913.6087.98811.4127.6126.23525.3425.4823.2519.5412.18
4926.53112.47520.3522.5423.5421.23618.4612.8112.5913.124924.329.0513.530.5729.12628.5628.0225.8121.5313.35
4937.69714.57222.2623.4325.7121.32620.2713.9813.7714.244935.17410.315.6933.5531.23630.6530.728.3524.3514.6
4948.93715.567224.125.4327.8722.56121.9115.1314.8915.414945.9811.8118.0436.3432.36231.2533.3230.9128.43515.71
49510.3517.28325.9926.32530.1724.26123.5216.2515.9916.644956.94113.3520.6739.3635.235.6435.7733.2329.3216.95
49611.9218.567827.8629.4532.4125.98625.4917.4917.1517.764968.04415.123.5342.1839.12538.4538.4535.7731.2518.14
49713.5820.23529.7931.2334.627.89327.3118.5718.3319.064979.12616.7526.6745.1542.12541.2341.0338.2534.2519.24
49815.3122.47331.6833.25636.9230.2628.9219.619.4420.0749810.3618.4629.9347.7645.23642.6543.5340.5135.4220.35
49917.224.83833.2335.1238.8535.21630.5620.5720.4421.0849911.6720.2733.250.4549.23648.2345.7542.7236.3321.4
50018.9426.478334.5935.67840.5138.26132.1221.4321.2721.9850012.921.9136.5652.5651.2651.6747.9344.6437.122.33
50120.7628.5436.137.12542.240.63733.2522.3222.0422.9950114.1423.5239.8654.8153.23652.6849.846.5737.8423.27
50222.3632.56737.2639.2543.5540.98234.2923.2322.8323.7350215.3325.4943.157.358.43655.3251.7348.1838.3224.29
50324.2633.567238.5440.2344.7941.26935.4223.9723.6524.4650316.6227.3146.1759.2159.23656.5453.2349.8638.6525.02
50425.834.562739.5941.68545.8241.64836.3324.5724.1925.1350417.6528.9248.5660.6560.76558.7854.651.0741.9225.72
50527.2835.67840.1542.3846.7642.69437.125.1724.7125.6150518.6930.5651.2761.7461.32659.2355.8852.1742.5626.26
50628.4436.12540.7542.987447.5143.99737.8425.4525.0926.1650619.6732.1253.6462.8462.36560.3456.7753.0143.6726.66
50729.5136.83741.2643.78548.0444.02538.3225.6425.426.450720.3933.2555.2563.7563.67861.2457.3553.7844.5327.06
50830.2537.1241.5943.97548.5344.72138.6525.9525.8426.7250820.8933.56757.0764.4763.98661.4957.8754.3846.4327.25
50931.0437.98741.8844.1548.6945.02139.0426.1426.0826.8250921.434.26758.2364.6664.12562.4558.3354.7846.9827.43
51031.4338.01242.0244.3248.9145.3239.1426.8726.2126.8451021.7534.67859.0664.7364.21962.7858.4455.1847.2627.49
51131.9138.3742.0144.4348.6345.20639.1126.0326.126.0851121.9435.12659.4464.6464.2363.3258.6755.2847.6827.63
51232.138.12541.944.6148.2144.21638.9325.9925.9926.7651222.0535.6159.7764.6363.26162.3458.5655.1746.9427.66
51332.0537.987741.7544.2348.0243.65738.6126.0225.8826.751322.0535.23659.5564.2663.12962.1958.2654.845.6827.42
51431.6537.45241.2843.76547.7243.19538.2525.9125.7326.4851422.135.159.1963.9862.31261.2357.6354.5445.2327.18
51531.1936.89540.9142.96247.4442.17537.9125.5525.5226.2951521.8334.12658.7263.360.23160.1657.2553.8744.7527.03
51630.8335.5640.6142.56346.6641.92437.6825.3125.2625.9551621.633.6257.7762.6561.23959.5656.5753.243.2626.95
51730.1934.675340.0542.1246.0741.82737.3124.9224.9425.6151721.233.29656.361.7860.98259.2355.9252.6842.6926.61
51829.5633.98739.4241.65745.3841.79536.5824.7124.7525.2851820.7932.0555.1461.2460.84358.9655.2152.0941.2826.28
51928.7732.85438.7440.49844.6640.87536.1324.3624.5125.0451920.2631.6553.5960.4759.23658.7554.4951.4741.125.9
52027.932.36438.1640.21543.9540.67235.4823.8223.9424.6152019.6831.1951.9659.5359.126658.2353.6750.6940.4625.53
52126.9231.59637.6939.25843.1940.51834.8323.3623.5824.4152119.1330.8350.6658.5658.32857.3452.9949.9139.5125.1
52226.0231.27437.0739.142.5339.7434.3123.0423.3123.8552218.4730.1949.1357.4357.65456.4652.0949.2638.3524.64
52325.0630.48636.4238.4341.6839.47133.8422.6722.8723.4452317.9829.5647.3856.5856.23856.2451.1948.4837.2624.18
52424.0829.9835.8337.8441.137.57233.322.422.623.1452417.3728.7745.5355.8555.12655.6750.4447.5736.5823.66
52523.1929.12535.2437.2140.5337.19232.7722.0222.2322.6952516.6727.944.0754.9853.68254.2349.8746.935.4123.26
52622.1428.45834.5436.5439.9636.38332.221.6721.922.4152615.9826.9242.2554.154.86753.1649.1146.1634.3822.99
52721.2528.12534.0436.239.135.47231.7521.3421.5622.1452715.3326.0240.4953.0852.12852.3548.3945.5833.2722.65
52820.4127.68533.3335.4238.5234.32831.2421.0621.3721.8452814.6725.0638.8852.3551.23651.9647.6344.8632.9622.4
52919.6227.12533.0735.2138.234.12830.7920.8821.0621.4852913.9924.0837.2751.5850.23649.2646.7644.1932.7522.17
53018.7326.98432.634.7537.6233.82530.3620.5820.7321.1753013.423.1935.7650.8849.23648.2345.9843.5631.5721.89
53117.9226.34132.2934.5636.9733.72630.0220.3620.4121.0453112.7822.1434.3950.0549.3248.1545.5242.9830.2721.51
53217.1625.87431.8533.4536.4333.46129.6620.0320.1820.8853212.2121.2533.1549.4148.9647.2344.8442.3730.4621.23
53316.4724.9331.2733.2536.0432.15629.1819.7719.9220.5753311.7220.4131.948.7448.1247.7844.4241.9329.5721.14
53415.8124.5130.8432.8435.6932.01228.7519.4819.7720.2853411.1219.6230.5548.247.1346.7843.9441.4129.3420.81
53515.1224.0130.5232.5135.5231.87628.4719.1919.5720.1353510.6418.7329.3847.6946.8946.2443.5340.9428.4520.55
53614.5223.630.1532.1535.0231.73228.1419.1119.2319.8453610.2317.9228.3147.3446.5745.6842.8840.628.1420.29
53714.0223.1629.8431.8434.5531.57227.6818.8518.9519.45379.82317.1627.446.7745.2145.3642.4940.227.5620.15
53813.3722.7329.5731.5434.330.57127.418.7518.7619.245389.44216.4726.3346.3145.1244.1241.8139.7527.4319.85
53912.8822.2329.2431.2533.9630.25127.0618.518.6619.155399.06315.8125.4545.744.6743.2641.3339.1426.5819.69
54012.3821.8728.9730.9533.3929.78526.6718.1918.3718.925408.7915.1224.6245.2144.2343.1640.9838.6626.3619.46
54111.9821.4128.530.5432.9728.5626.3817.9318.2418.685418.5214.5223.8444.6843.1242.6740.5138.2425.3819.21
54211.5520.8128.1430.1232.628.45626.0817.7817.8718.475428.19214.0223.054442.6742.3639.9237.7525.118.94
54311.1420.1827.5829.56732.0827.34525.7417.5917.6218.235437.90613.3722.3743.5842.1241.6739.3237.2624.7318.6
54410.7620.4127.2229.2231.7427.12925.3317.3417.5117.935447.62812.8821.7542.9741.8641.2938.9436.6324.1618.38
54510.4719.6226.7928.7531.1726.89524.9317.0817.2917.75457.35712.3821.0342.3441.5640.2638.2936.0623.4718.19
5469.96218.6226.6328.6330.4326.78424.5116.781717.45467.19511.9820.4841.6740.6939.2637.6335.4922.4917.91
5479.55917.8226.0728.0130.0526.34624.0116.5916.6916.915477.03911.5519.9440.8939.1239.6837.0734.9421.5817.69
5489.35417.0925.4627.4629.5725.36823.616.2716.416.615486.81311.1419.2340.237.2338.2536.3934.4921.3817.26
5499.08216.4824.9726.9728.925.123.1615.9416.1116.425496.67310.7618.6839.4436.5435.2635.923420.1516.97
5508.75215.8424.3726.4728.224.98722.7315.5515.816.095506.42310.4718.0938.7336.4535.1935.0233.4119.2416.61
5518.46815.1823.825.76527.6724.76522.2315.2415.4615.75516.1399.96217.5237.736.2335.0234.2932.719.5416.23
5528.19914.5223.2524.78626.9924.21221.8714.9915.0115.285525.869.55916.9536.8335.2334.2633.3931.8328.5615.85
5537.88413.922.824.59826.3823.68121.4114.6614.715.045535.6359.35416.4335.9235.1234.2632.6130.9218.4515.5
5547.54113.3122.2324.37225.8522.98320.8114.2114.314.715545.4549.08215.6735.1134.2633.1631.6330.1418.2315.11
5557.17312.5621.6223.15625.1222.57620.1813.7613.9514.35555.2428.75215.0534.1234.1232.1731.0529.2817.9814.73
5566.89511.8821.0722.67824.1822.12919.6713.4113.5113.825565.0438.46814.4833.0733.6832.1930.1828.4817.4614.36
5576.61711.2920.5522.57323.421.68319.1412.9713.1213.45574.7758.19913.932.2433.5631.8529.2927.716.8413.89
5586.35810.6519.7622.12422.7221.36118.512.6412.6513.045584.5747.88413.3531.3132.4531.2728.4226.9816.3713.43
5596.0610.2319.2321.54322.0220.12617.8212.2512.3112.725594.317.54112.7830.331.2130.5827.5326.115.3713.07
5605.7399.82318.6221.34621.219.98217.1911.711.9312.35604.1417.17312.1629.2530.6730.2626.6525.2515.2612.72
5615.3979.44217.8220.78420.5519.57216.6311.2911.511.85613.9446.89511.6128.1128.4527.8725.5524.2214.9512.25
5625.1779.06317.0919.56219.7819.2115.9510.9111.0511.285623.7426.61711.0327.0928.1227.6324.5523.214.2511.71
5634.8938.7916.4819.25618.918.3215.3710.4810.5510.785633.5246.35810.5326.2927.65426.4723.5322.5513.5711.23
5644.6258.5215.8418.54618.2817.93614.79.93510.1910.45643.3256.069.96525.1226.4325.3722.6321.712.5710.83
5654.3188.19215.1817.25917.4317.26114.099.4819.7099.9635653.1175.7399.36923.9922.5421.8921.7220.8812.3910.43
5664.0647.90614.5216.12616.6316.113.499.0779.3319.4785662.8975.3978.78822.821.6820.9720.8219.9411.469.961
5673.8587.62813.915.32515.8515.4212.88.7548.9379.025672.7155.1778.31721.8520.12520.0519.819.0210.269.492
5683.5747.35713.3114.87515.1914.23512.268.4388.5518.6195682.5324.8937.8520.8719.4319.2619.0318.059.868.997
5693.2937.19512.5614.2115.0113.58611.698.0278.1258.3085692.3674.6257.37319.9419.3418.7818.1317.299.568.602
5703.0267.03911.8813.25814.28512.52411.097.5547.7237.8795702.2214.3186.9119.0118.6917.9617.2316.459.468.248
5712.8676.81311.2912.45213.48311.5910.517.2427.3847.4475712.054.0646.5491818.3217.3616.3815.718.957.873
5722.6646.67310.6511.25312.23511.419.9826.8716.9577.135721.8623.8586.13417.1217.3416.4915.5914.848.367.449
5732.4486.42310.110.87511.85710.2359.4976.5176.5696.8055731.7343.5745.71516.3217.2316.0214.7514.18.166.995
5742.2796.1399.60210.25411.2519.8569.036.1386.286.4975741.5993.2935.3215.5815.7815.2314.0713.527.346.727
5752.0945.869.17310.12910.989.5328.5525.8795.9936.1295751.4763.0265.04614.8615.2314.9613.412.867.146.405
5761.9135.6358.6619.87410.5839.1258.1515.585.6595.7865761.3522.8674.70814.0314.6813.4812.7512.16.976.061
5771.7175.4548.2789.25110.1258.7347.6795.2755.3395.4775771.2212.6644.39613.3313.2313.0412.1111.456.875.756
5781.615.2427.8438.9859.938.2317.3075.0045.1645.2245781.0792.4484.01912.6313.1212.9511.4210.896.7345.423
5791.4765.0437.4158.1259.2318.16.9124.7824.8524.9675790.9772.2793.71611.9510.2310.2810.8610.346.635.178
5801.3854.7757.0427.9238.8937.8566.6254.5694.6024.7085800.9042.0943.47611.310.110.0410.359.8926.454.904
5811.2354.5746.6567.258.2517.2356.2434.2734.3794.4375810.841.9133.24710.699.459.659.8399.3536.214.668
5821.1454.316.3026.8437.8326.8745.9444.0914.1034.1875820.7571.7173.04110.189.219.019.2718.8695.984.395
5831.0394.1416.0356.5827.3516.3475.6373.8163.9323.9255830.7061.612.8279.6628.658.688.8728.5045.864.212
5840.963.9445.7646.5216.9826.2365.3033.6633.7083.755840.6181.4762.6049.2478.238.678.5618.095.724.008
5850.8663.7425.4516.2016.2385.8655.0583.4673.5423.6025850.5441.3852.4348.8648.548.468.1597.7685.633.802
5860.7663.5245.1165.9836.0185.3464.7643.2813.3223.4095860.4941.2352.2848.47.237.947.7597.3785.123.601
5870.6963.3254.8095.6215.7165.1254.4953.1253.1583.2315870.4221.1452.1178.0447.547.457.3686.9784.823.415
5880.6453.1174.5935.215.4484.7454.3072.9953.0073.0615880.4011.0391.9977.6047.127.26.9886.6854.763.267
5890.6232.8974.4764.8295.1464.4774.1072.8322.8292.9395890.3480.961.8457.2847.646.976.6666.2944.653.075
5900.5482.7154.2654.6724.9474.1263.8952.7192.7452.7885900.3130.8661.6936.9436.436.876.3456.0524.522.905
5910.482.5324.0274.3254.7333.9823.6672.552.6652.6155910.2550.7661.5566.6016.126.496.0745.7854.422.778
5920.4142.3673.8284.2154.4293.5473.5152.3892.5372.4775920.1930.6961.466.3266.345.865.8155.494.322.635
5930.3812.2213.6214.1854.2393.4563.4062.2942.4042.3285930.1630.6451.3776.1045.985.365.5515.2523.972.521
5940.3082.053.4783.8274.0393.4213.2062.1862.2462.2235940.1520.6231.2955.85.765.2915.3315.0053.862.392
5950.2751.8623.3363.7213.8863.13.0252.1082.1662.1435950.1060.5481.2285.485.235.125.0574.7483.752.266
5960.2511.7343.1423.6123.6952.9152.8761.9752.042.0465960.0760.481.1525.224.764.964.8054.5333.692.177
5970.2081.5992.9943.3153.4672.8652.7411.8471.9041.9615970.0470.4141.0674.9754.654.764.5524.3193.572.042
5980.1711.4762.8473.2713.3122.7362.5631.7461.81.8325980.0230.3810.9814.7084.124.264.3144.0693.451.939
5990.1361.3522.7083.1853.1482.6352.4111.7031.6771.7285990.0090.3080.8954.5293.983.924.1173.8863.271.835
6000.0921.2212.5342.853.012.5192.3031.5821.6021.656000.0020.2750.8164.2813.763.653.8633.6792.851.775
Sheet2
Sheet3
-
Fluorescent Intensity Released by Nanocapsules in the Absence of Light
Chart1
0000.818
0000.828
0000.8
0000.878
0000.906
0000.969
0001.027
0001.102
0001.227
0001.371
0001.51
0001.714
0001.946
0002.195
0002.468
000.0782.645
00.1250.2113.122
00.2540.3683.751
00.4370.5764.484
0.0070.5360.7995.328
0.0530.9321.116.193
0.1611.3461.4337.324
0.2541.8211.8358.49
0.4022.1992.3259.818
0.622.6272.95911.35
0.8753.0963.6813.08
1.1583.5964.51115.15
1.4984.2865.47117.4
1.9275.0186.61619.62
2.4175.858.04822
2.9866.8429.63824.74
3.6087.98811.4127.61
4.329.0513.530.57
5.17410.315.6933.55
5.9811.8118.0436.34
6.94113.3520.6739.36
8.04415.123.5342.18
9.12616.7526.6745.15
10.3618.4629.9347.76
11.6720.2733.250.45
12.921.9136.5652.56
14.1423.5239.8654.81
15.3325.4943.157.3
16.6227.3146.1759.21
17.6528.9248.5660.65
18.6930.5651.2761.74
19.6732.1253.6462.84
20.3933.2555.2563.75
20.8933.56757.0764.47
21.434.26758.2364.66
21.7534.67859.0664.73
21.9435.12659.4464.64
22.0535.6159.7764.63
22.0535.23659.5564.26
22.135.159.1963.98
21.8334.12658.7263.3
21.633.6257.7762.65
21.233.29656.361.78
20.7932.0555.1461.24
20.2631.6553.5960.47
19.6831.1951.9659.53
19.1330.8350.6658.56
18.4730.1949.1357.43
17.9829.5647.3856.58
17.3728.7745.5355.85
16.6727.944.0754.98
15.9826.9242.2554.1
15.3326.0240.4953.08
14.6725.0638.8852.35
13.9924.0837.2751.58
13.423.1935.7650.88
12.7822.1434.3950.05
12.2121.2533.1549.41
11.7220.4131.948.74
11.1219.6230.5548.2
10.6418.7329.3847.69
10.2317.9228.3147.34
9.82317.1627.446.77
9.44216.4726.3346.31
9.06315.8125.4545.7
8.7915.1224.6245.21
8.5214.5223.8444.68
8.19214.0223.0544
7.90613.3722.3743.58
7.62812.8821.7542.97
7.35712.3821.0342.34
7.19511.9820.4841.67
7.03911.5519.9440.89
6.81311.1419.2340.2
6.67310.7618.6839.44
6.42310.4718.0938.73
6.1399.96217.5237.7
5.869.55916.9536.83
5.6359.35416.4335.92
5.4549.08215.6735.11
5.2428.75215.0534.12
5.0438.46814.4833.07
4.7758.19913.932.24
4.5747.88413.3531.31
4.317.54112.7830.3
4.1417.17312.1629.25
3.9446.89511.6128.11
3.7426.61711.0327.09
3.5246.35810.5326.29
3.3256.069.96525.12
3.1175.7399.36923.99
2.8975.3978.78822.8
2.7155.1778.31721.85
2.5324.8937.8520.87
2.3674.6257.37319.94
2.2214.3186.9119.01
2.054.0646.54918
1.8623.8586.13417.12
1.7343.5745.71516.32
1.5993.2935.3215.58
1.4763.0265.04614.86
1.3522.8674.70814.03
1.2212.6644.39613.33
1.0792.4484.01912.63
0.9772.2793.71611.95
0.9042.0943.47611.3
0.841.9133.24710.69
0.7571.7173.04110.18
0.7061.612.8279.662
0.6181.4762.6049.247
0.5441.3852.4348.864
0.4941.2352.2848.4
0.4221.1452.1178.044
0.4011.0391.9977.604
0.3480.961.8457.284
0.3130.8661.6936.943
0.2550.7661.5566.601
0.1930.6961.466.326
0.1630.6451.3776.104
0.1520.6231.2955.8
0.1060.5481.2285.48
0.0760.481.1525.22
0.0470.4141.0674.975
0.0230.3810.9814.708
0.0090.3080.8954.529
0.0020.2750.8164.281
Intensity after 5 min
Intensity after 10 min
Intensity after 15 min
Intensity after 20 min
Wavelength (nm)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules Energized by UV Light
Chart2
000.2360.8180.952
000.2460.8281.24
000.2510.81.235
000.2440.8781.643
000.2690.8951.782
00.1340.3120.9691.709
00.2450.3510.9951.923
00.2780.3871.1022.352
00.3460.461.2272.63
00.480.5521.3712.873
00.9340.6561.512.832
01.1450.791.7142.965
01.2580.9211.9462.987
01.451.1232.1953.012
01.3781.3742.4683.784
01.4561.6632.8583.926
01.6681.9753.3494.324
01.7682.4353.8544.567
01.8352.8854.4745.432
0.0712.5463.355.1785.632
0.2132.7683.9956.0826.125
0.3562.8754.7537.0497.432
0.522.9875.6268.2028.346
0.7453.0116.4828.5549.231
1.014.5637.6189.8489.658
1.3594.6788.7411.313.235
1.8024.8799.94613.0415.57
2.3285.32611.4814.8515.687
2.9386.43213.1516.9318.325
3.6167.45614.941919.543
4.5129.45316.620.8921.1
5.45710.23418.4321.421.25
6.53112.47520.3522.5423.54
7.69714.57222.2623.4325.71
8.93715.567224.125.4327.87
10.3517.28325.9926.32530.17
11.9218.567827.8629.4532.41
13.5820.23529.7931.2334.6
15.3122.47331.6833.25636.92
17.224.83833.2335.1238.85
18.9426.478334.5935.67840.51
20.7628.5436.137.12542.2
22.3632.56737.2639.2543.55
24.2633.567238.5440.2344.79
25.834.562739.5941.68545.82
27.2835.67840.1542.3846.76
28.4436.12540.7542.987447.51
29.5136.83741.2643.78548.04
30.2537.1241.5943.97548.53
31.0437.98741.8844.1548.69
31.4338.01242.0244.3248.91
31.9138.3742.0144.4348.63
32.138.12541.944.6148.21
32.0537.987741.7544.2348.02
31.6537.45241.2843.76547.72
31.1936.89540.9142.96247.44
30.8335.5640.6142.56346.66
30.1934.675340.0542.1246.07
29.5633.98739.4241.65745.38
28.7732.85438.7440.49844.66
27.932.36438.1640.21543.95
26.9231.59637.6939.25843.19
26.0231.27437.0739.142.53
25.0630.48636.4238.4341.68
24.0829.9835.8337.8441.1
23.1929.12535.2437.2140.53
22.1428.45834.5436.5439.96
21.2528.12534.0436.239.1
20.4127.68533.3335.4238.52
19.6227.12533.0735.2138.2
18.7326.98432.634.7537.62
17.9226.34132.2934.5636.97
17.1625.87431.8533.4536.43
16.4724.9331.2733.2536.04
15.8124.5130.8432.8435.69
15.1224.0130.5232.5135.52
14.5223.630.1532.1535.02
14.0223.1629.8431.8434.55
13.3722.7329.5731.5434.3
12.8822.2329.2431.2533.96
12.3821.8728.9730.9533.39
11.9821.4128.530.5432.97
11.5520.8128.1430.1232.6
11.1420.1827.5829.56732.08
10.7620.4127.2229.2231.74
10.4719.6226.7928.7531.17
9.96218.6226.6328.6330.43
9.55917.8226.0728.0130.05
9.35417.0925.4627.4629.57
9.08216.4824.9726.9728.9
8.75215.8424.3726.4728.2
8.46815.1823.825.76527.67
8.19914.5223.2524.78626.99
7.88413.922.824.59826.38
7.54113.3122.2324.37225.85
7.17312.5621.6223.15625.12
6.89511.8821.0722.67824.18
6.61711.2920.5522.57323.4
6.35810.6519.7622.12422.72
6.0610.2319.2321.54322.02
5.7399.82318.6221.34621.2
5.3979.44217.8220.78420.55
5.1779.06317.0919.56219.78
4.8938.7916.4819.25618.9
4.6258.5215.8418.54618.28
4.3188.19215.1817.25917.43
4.0647.90614.5216.12616.63
3.8587.62813.915.32515.85
3.5747.35713.3114.87515.19
3.2937.19512.5614.2115.01
3.0267.03911.8813.25814.285
2.8676.81311.2912.45213.483
2.6646.67310.6511.25312.235
2.4486.42310.110.87511.857
2.2796.1399.60210.25411.251
2.0945.869.17310.12910.98
1.9135.6358.6619.87410.583
1.7175.4548.2789.25110.125
1.615.2427.8438.9859.93
1.4765.0437.4158.1259.231
1.3854.7757.0427.9238.893
1.2354.5746.6567.258.251
1.1454.316.3026.8437.832
1.0394.1416.0356.5827.351
0.963.9445.7646.5216.982
0.8663.7425.4516.2016.238
0.7663.5245.1165.9836.018
0.6963.3254.8095.6215.716
0.6453.1174.5935.215.448
0.6232.8974.4764.8295.146
0.5482.7154.2654.6724.947
0.482.5324.0274.3254.733
0.4142.3673.8284.2154.429
0.3812.2213.6214.1854.239
0.3082.053.4783.8274.039
0.2751.8623.3363.7213.886
0.2511.7343.1423.6123.695
0.2081.5992.9943.3153.467
0.1711.4762.8473.2713.312
0.1361.3522.7083.1853.148
0.0921.2212.5342.853.01
Intensity after 5 min
Intensity after 10 min
Intensity after 15 min
Intensity after 20 min
Intensity after 25 min
Wavelength (nm)
Fluorescent Intensity
Chart3
32.122.1
38.3735.61
42.0259.77
44.6164.73
48.9164.23
45.3263.32
39.1458.72
26.8755.28
26.2147.68
26.0827.63
Nanocapsules under the absence of light
Nanocapsules energized by UV light
Time (min)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules over Time
Chart4
32.122.1
38.3735.61
42.0259.77
44.6164.73
48.9120
In the Absence of Light
Energized by UV Light
Time (min)
Fluorescent Intensity
Increasing Fluorescent Intensity Released by Nanocapsules over Time
Sheet1
DK1UV1TimePeaks
Data PointsData PointsDKUVDKUV
nmDataDataDataDataDataDataDatanmDataDataDataDataDataData032.122.122.9824.12
460000.2360.8180.9520.8530.3715.4575.1644.6854600000.8180.8010.7940.3610.3510.3710.236538.3735.6126.6929.31
461000.2460.8281.240.9340.3995.3595.1614.4894610000.8280.8670.8120.3790.3670.3990.2461042.0259.7727.729.6
462000.2510.81.2350.9520.3554.7494.7284.0284620000.80.8430.8250.3930.3870.3550.2511544.6164.7329.632.19
463000.2440.8781.6431.1560.3564.0224.0453.4224630000.8780.8310.8340.4260.4150.3560.2442048.9164.2330.447.75
464000.2690.8951.7821.2560.3553.4083.3822.8714640000.9060.8920.8660.4820.4260.3550.2692545.3263.3234.640.32
46500.1340.3120.9691.7091.3560.3532.8632.8432.3854650000.9690.9350.9120.570.4860.3530.3123039.1458.7227.833.21
46600.2450.3510.9951.9231.5720.3762.4882.4582.074660001.0270.9750.9430.6690.5830.3760.3516026.8755.2823.6227.67
46700.2780.3871.1022.3521.6920.4282.3222.2241.9224670001.1021.0480.9650.7580.7230.4280.38712026.2147.6820.4524.68
46800.3460.461.2272.631.9280.4972.2242.1151.8714680001.2271.1531.2560.8540.7930.4970.4624026.0827.6319.2319.16
46900.480.5521.3712.8732.0510.5522.1692.0791.8944690001.3711.2251.3460.9860.8950.5520.552
47000.9340.6561.512.8322.1560.6182.1081.9951.8444700001.511.361.8671.1591.0450.6180.656
47101.1450.791.7142.9652.2560.7412.0511.9731.7634710001.7141.511.6731.3521.2450.7410.79
47201.2580.9211.9462.9872.4160.8652.061.9281.7994720001.9461.7541.6921.5681.3560.8650.921
47301.451.1232.1953.0122.7121.0432.1281.9781.8734730002.1951.9761.8761.8441.5861.0431.123
47401.3781.3742.4683.7842.8361.2432.1532.0131.9574740002.4682.2472.1252.2391.6791.2431.374032.122.1
47501.4561.6632.8583.9263.2361.5342.1972.0552.012475000.0782.6452.6332.5462.8582.5981.5341.663538.3735.61
47601.6681.9753.3494.3243.5671.8212.2812.1222.12347600.1250.2113.1223.2363.1253.3493.0631.8211.9751042.0259.77
47701.7682.4353.8544.5673.6322.1992.4762.3162.2947700.2540.3683.7513.5673.2353.8543.5612.1992.4351544.6164.73
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4926.53112.47520.3522.5423.5421.23618.4612.8112.5913.124924.329.0513.530.5729.12628.5628.0225.8121.5313.35
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5537.88413.922.824.59826.3823.68121.4114.6614.715.045535.6359.35416.4335.9235.1234.2632.6130.9218.4515.5
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5557.17312.5621.6223.15625.1222.57620.1813.7613.9514.35555.2428.75215.0534.1234.1232.1731.0529.2817.9814.73
5566.89511.8821.0722.67824.1822.12919.6713.4113.5113.825565.0438.46814.4833.0733.6832.1930.1828.4817.4614.36
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5664.0647.90614.5216.12616.6316.113.499.0779.3319.4785662.8975.3978.78822.821.6820.9720.8219.9411.469.961
5673.8587.62813.915.32515.8515.4212.88.7548.9379.025672.7155.1778.31721.8520.12520.0519.819.0210.269.492
5683.5747.35713.3114.87515.1914.23512.268.4388.5518.6195682.5324.8937.8520.8719.4319.2619.0318.059.868.997
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5712.8676.81311.2912.45213.48311.5910.517.2427.3847.4475712.054.0646.5491818.3217.3616.3815.718.957.873
5722.6646.67310.6511.25312.23511.419.9826.8716.9577.135721.8623.8586.13417.1217.3416.4915.5914.848.367.449
5732.4486.42310.110.87511.85710.2359.4976.5176.5696.8055731.7343.5745.71516.3217.2316.0214.7514.18.166.995
5742.2796.1399.60210.25411.2519.8569.036.1386.286.4975741.5993.2935.3215.5815.7815.2314.0713.527.346.727
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5781.615.2427.8438.9859.938.2317.3075.0045.1645.2245781.0792.4484.01912.6313.1212.9511.4210.896.7345.423
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5821.1454.316.3026.8437.8326.8745.9444.0914.1034.1875820.7571.7173.04110.189.219.019.2718.8695.984.395
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5840.963.9445.7646.5216.9826.2365.3033.6633.7083.755840.6181.4762.6049.2478.238.678.5618.095.724.008
5850.8663.7425.4516.2016.2385.8655.0583.4673.5423.6025850.5441.3852.4348.8648.548.468.1597.7685.633.802
5860.7663.5245.1165.9836.0185.3464.7643.2813.3223.4095860.4941.2352.2848.47.237.947.7597.3785.123.601
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5910.482.5324.0274.3254.7333.9823.6672.552.6652.6155910.2550.7661.5566.6016.126.496.0745.7854.422.778
5920.4142.3673.8284.2154.4293.5473.5152.3892.5372.4775920.1930.6961.466.3266.345.865.8155.494.322.635
5930.3812.2213.6214.1854.2393.4563.4062.2942.4042.3285930.1630.6451.3776.1045.985.365.5515.2523.972.521
5940.3082.053.4783.8274.0393.4213.2062.1862.2462.2235940.1520.6231.2955.85.765.2915.3315.0053.862.392
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6000.0921.2212.5342.853.012.5192.3031.5821.6021.656000.0020.2750.8164.2813.763.653.8633.6792.851.775
Sheet2
Sheet3
-
Increasing Fluorescent Intensity Released by Nanocapsules over Time
Chart1
0000.818
0000.828
0000.8
0000.878
0000.906
0000.969
0001.027
0001.102
0001.227
0001.371
0001.51
0001.714
0001.946
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0002.468
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00.1250.2113.122
00.2540.3683.751
00.4370.5764.484
0.0070.5360.7995.328
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0.1611.3461.4337.324
0.2541.8211.8358.49
0.4022.1992.3259.818
0.622.6272.95911.35
0.8753.0963.6813.08
1.1583.5964.51115.15
1.4984.2865.47117.4
1.9275.0186.61619.62
2.4175.858.04822
2.9866.8429.63824.74
3.6087.98811.4127.61
4.329.0513.530.57
5.17410.315.6933.55
5.9811.8118.0436.34
6.94113.3520.6739.36
8.04415.123.5342.18
9.12616.7526.6745.15
10.3618.4629.9347.76
11.6720.2733.250.45
12.921.9136.5652.56
14.1423.5239.8654.81
15.3325.4943.157.3
16.6227.3146.1759.21
17.6528.9248.5660.65
18.6930.5651.2761.74
19.6732.1253.6462.84
20.3933.2555.2563.75
20.8933.56757.0764.47
21.434.26758.2364.66
21.7534.67859.0664.73
21.9435.12659.4464.64
22.0535.6159.7764.63
22.0535.23659.5564.26
22.135.159.1963.98
21.8334.12658.7263.3
21.633.6257.7762.65
21.233.29656.361.78
20.7932.0555.1461.24
20.2631.6553.5960.47
19.6831.1951.9659.53
19.1330.8350.6658.56
18.4730.1949.1357.43
17.9829.5647.3856.58
17.3728.7745.5355.85
16.6727.944.0754.98
15.9826.9242.2554.1
15.3326.0240.4953.08
14.6725.0638.8852.35
13.9924.0837.2751.58
13.423.1935.7650.88
12.7822.1434.3950.05
12.2121.2533.1549.41
11.7220.4131.948.74
11.1219.6230.5548.2
10.6418.7329.3847.69
10.2317.9228.3147.34
9.82317.1627.446.77
9.44216.4726.3346.31
9.06315.8125.4545.7
8.7915.1224.6245.21
8.5214.5223.8444.68
8.19214.0223.0544
7.90613.3722.3743.58
7.62812.8821.7542.97
7.35712.3821.0342.34
7.19511.9820.4841.67
7.03911.5519.9440.89
6.81311.1419.2340.2
6.67310.7618.6839.44
6.42310.4718.0938.73
6.1399.96217.5237.7
5.869.55916.9536.83
5.6359.35416.4335.92
5.4549.08215.6735.11
5.2428.75215.0534.12
5.0438.46814.4833.07
4.7758.19913.932.24
4.5747.88413.3531.31
4.317.54112.7830.3
4.1417.17312.1629.25
3.9446.89511.6128.11
3.7426.61711.0327.09
3.5246.35810.5326.29
3.3256.069.96525.12
3.1175.7399.36923.99
2.8975.3978.78822.8
2.7155.1778.31721.85
2.5324.8937.8520.87
2.3674.6257.37319.94
2.2214.3186.9119.01
2.054.0646.54918
1.8623.8586.13417.12
1.7343.5745.71516.32
1.5993.2935.3215.58
1.4763.0265.04614.86
1.3522.8674.70814.03
1.2212.6644.39613.33
1.0792.4484.01912.63
0.9772.2793.71611.95
0.9042.0943.47611.3
0.841.9133.24710.69
0.7571.7173.04110.18
0.7061.612.8279.662
0.6181.4762.6049.247
0.5441.3852.4348.864
0.4941.2352.2848.4
0.4221.1452.1178.044
0.4011.0391.9977.604
0.3480.961.8457.284
0.3130.8661.6936.943
0.2550.7661.5566.601
0.1930.6961.466.326
0.1630.6451.3776.104
0.1520.6231.2955.8
0.1060.5481.2285.48
0.0760.481.1525.22
0.0470.4141.0674.975
0.0230.3810.9814.708
0.0090.3080.8954.529
0.0020.2750.8164.281
Intensity after 5 min
Intensity after 10 min
Intensity after 15 min
Intensity after 20 min
Wavelength (nm)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules Energized by UV Light
Chart2
000.2360.8180.952
000.2460.8281.24
000.2510.81.235
000.2440.8781.643
000.2690.8951.782
00.1340.3120.9691.709
00.2450.3510.9951.923
00.2780.3871.1022.352
00.3460.461.2272.63
00.480.5521.3712.873
00.9340.6561.512.832
01.1450.791.7142.965
01.2580.9211.9462.987
01.451.1232.1953.012
01.3781.3742.4683.784
01.4561.6632.8583.926
01.6681.9753.3494.324
01.7682.4353.8544.567
01.8352.8854.4745.432
0.0712.5463.355.1785.632
0.2132.7683.9956.0826.125
0.3562.8754.7537.0497.432
0.522.9875.6268.2028.346
0.7453.0116.4828.5549.231
1.014.5637.6189.8489.658
1.3594.6788.7411.313.235
1.8024.8799.94613.0415.57
2.3285.32611.4814.8515.687
2.9386.43213.1516.9318.325
3.6167.45614.941919.543
4.5129.45316.620.8921.1
5.45710.23418.4321.421.25
6.53112.47520.3522.5423.54
7.69714.57222.2623.4325.71
8.93715.567224.125.4327.87
10.3517.28325.9926.32530.17
11.9218.567827.8629.4532.41
13.5820.23529.7931.2334.6
15.3122.47331.6833.25636.92
17.224.83833.2335.1238.85
18.9426.478334.5935.67840.51
20.7628.5436.137.12542.2
22.3632.56737.2639.2543.55
24.2633.567238.5440.2344.79
25.834.562739.5941.68545.82
27.2835.67840.1542.3846.76
28.4436.12540.7542.987447.51
29.5136.83741.2643.78548.04
30.2537.1241.5943.97548.53
31.0437.98741.8844.1548.69
31.4338.01242.0244.3248.91
31.9138.3742.0144.4348.63
32.138.12541.944.6148.21
32.0537.987741.7544.2348.02
31.6537.45241.2843.76547.72
31.1936.89540.9142.96247.44
30.8335.5640.6142.56346.66
30.1934.675340.0542.1246.07
29.5633.98739.4241.65745.38
28.7732.85438.7440.49844.66
27.932.36438.1640.21543.95
26.9231.59637.6939.25843.19
26.0231.27437.0739.142.53
25.0630.48636.4238.4341.68
24.0829.9835.8337.8441.1
23.1929.12535.2437.2140.53
22.1428.45834.5436.5439.96
21.2528.12534.0436.239.1
20.4127.68533.3335.4238.52
19.6227.12533.0735.2138.2
18.7326.98432.634.7537.62
17.9226.34132.2934.5636.97
17.1625.87431.8533.4536.43
16.4724.9331.2733.2536.04
15.8124.5130.8432.8435.69
15.1224.0130.5232.5135.52
14.5223.630.1532.1535.02
14.0223.1629.8431.8434.55
13.3722.7329.5731.5434.3
12.8822.2329.2431.2533.96
12.3821.8728.9730.9533.39
11.9821.4128.530.5432.97
11.5520.8128.1430.1232.6
11.1420.1827.5829.56732.08
10.7620.4127.2229.2231.74
10.4719.6226.7928.7531.17
9.96218.6226.6328.6330.43
9.55917.8226.0728.0130.05
9.35417.0925.4627.4629.57
9.08216.4824.9726.9728.9
8.75215.8424.3726.4728.2
8.46815.1823.825.76527.67
8.19914.5223.2524.78626.99
7.88413.922.824.59826.38
7.54113.3122.2324.37225.85
7.17312.5621.6223.15625.12
6.89511.8821.0722.67824.18
6.61711.2920.5522.57323.4
6.35810.6519.7622.12422.72
6.0610.2319.2321.54322.02
5.7399.82318.6221.34621.2
5.3979.44217.8220.78420.55
5.1779.06317.0919.56219.78
4.8938.7916.4819.25618.9
4.6258.5215.8418.54618.28
4.3188.19215.1817.25917.43
4.0647.90614.5216.12616.63
3.8587.62813.915.32515.85
3.5747.35713.3114.87515.19
3.2937.19512.5614.2115.01
3.0267.03911.8813.25814.285
2.8676.81311.2912.45213.483
2.6646.67310.6511.25312.235
2.4486.42310.110.87511.857
2.2796.1399.60210.25411.251
2.0945.869.17310.12910.98
1.9135.6358.6619.87410.583
1.7175.4548.2789.25110.125
1.615.2427.8438.9859.93
1.4765.0437.4158.1259.231
1.3854.7757.0427.9238.893
1.2354.5746.6567.258.251
1.1454.316.3026.8437.832
1.0394.1416.0356.5827.351
0.963.9445.7646.5216.982
0.8663.7425.4516.2016.238
0.7663.5245.1165.9836.018
0.6963.3254.8095.6215.716
0.6453.1174.5935.215.448
0.6232.8974.4764.8295.146
0.5482.7154.2654.6724.947
0.482.5324.0274.3254.733
0.4142.3673.8284.2154.429
0.3812.2213.6214.1854.239
0.3082.053.4783.8274.039
0.2751.8623.3363.7213.886
0.2511.7343.1423.6123.695
0.2081.5992.9943.3153.467
0.1711.4762.8473.2713.312
0.1361.3522.7083.1853.148
0.0921.2212.5342.853.01
Intensity after 5 min
Intensity after 10 min
Intensity after 15 min
Intensity after 20 min
Intensity after 25 min
Wavelength (nm)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules in the Absence of Light
Chart3
32.122.1
38.3735.61
42.0259.77
44.6164.73
48.9164.23
45.3263.32
39.1458.72
26.8755.28
26.2147.68
26.0827.63
Nanocapsules under the absence of light
Nanocapsules energized by UV light
Time (min)
Fluorescent Intensity
Fluorescent Intensity Released by Nanocapsules over Time
Chart4
32.122.1
38.3735.61
42.0259.77
44.6164.73
48.9120
In the Absence of Light
Energized by UV Light
Time (min)
Fluorescent Intensity
Sheet1
DK1UV1TimePeaks
Data PointsData PointsDKUVDKUV
nmDataDataDataDataDataDataDatanmDataDataDataDataDataData032.122.122.9824.12
460000.2360.8180.9520.8530.3715.4575.1644.6854600000.8180.8010.7940.3610.3510.3710.236538.3735.6126.6929.31
461000.2460.8281.240.9340.3995.3595.1614.4894610000.8280.8670.8120.3790.3670.3990.2461042.0259.7727.729.6
462000.2510.81.2350.9520.3554.7494.7284.0284620000.80.8430.8250.3930.3870.3550.2511544.6164.7329.632.19
463000.2440.8781.6431.1560.3564.0224.0453.4224630000.8780.8310.8340.4260.4150.3560.2442048.9164.2330.447.75
464000.2690.8951.7821.2560.3553.4083.3822.8714640000.9060.8920.8660.4820.4260.3550.2692545.3263.3234.640.32
46500.1340.3120.9691.7091.3560.3532.8632.8432.3854650000.9690.9350.9120.570.4860.3530.3123039.1458.7227.833.21
46600.2450.3510.9951.9231.5720.3762.4882.4582.074660001.0270.9750.9430.6690.5830.3760.3516026.8755.2823.6227.67
46700.2780.3871.1022.3521.6920.4282.3222.2241.9224670001.1021.0480.9650.7580.7230.4280.38712026.2147.6820.4524.68
46800.3460.461.2272.631.9280.4972.2242.1151.8714680001.2271.1531.2560.8540.7930.4970.4624026.0827.6319.2319.16
46900.480.5521.3712.8732.0510.5522.1692.0791.8944690001.3711.2251.3460.9860.8950.5520.552
47000.9340.6561.512.8322.1560.6182.1081.9951.8444700001.511.361.8671.1591.0450.6180.656
47101.1450.791.7142.9652.2560.7412.0511.9731.7634710001.7141.511.6731.3521.2450.7410.79
47201.2580.9211.9462.9872.4160.8652.061.9281.7994720001.9461.7541.6921.5681.3560.8650.921
47301.451.1232.1953.0122.7121.0432.1281.9781.8734730002.1951.9761.8761.8441.5861.0431.123
47401.3781.3742.4683.7842.8361.2432.1532.0131.9574740002.4682.2472.1252.2391.6791.2431.374032.122.1
47501.4561.6632.8583.9263.2361.5342.1972.0552.012475000.0782.6452.6332.5462.8582.5981.5341.663538.3735.61
47601.6681.9753.3494.3243.5671.8212.2812.1222.12347600.1250.2113.1223.2363.1253.3493.0631.8211.9751042.0259.77
47701.7682.4353.8544.5673.6322.1992.4762.3162.2947700.2540.3683.7513.5673.2353.8543.5612.1992.4351544.6164.73
47801.8352.8854.4745.4323.7352.6272.6762.5222.50947800.4370.5764.4844.3264.1294.4744.0962.6272.8852048.91
4790.0712.5463.355.1785.6324.2163.0962.9322.7392.7754790.0070.5360.7995.3285.2314.685.1784.7343.0963.5625
4800.2132.7683.9956.0826.1254.4563.5963.2943.1043.1974800.0530.9321.116.1936.2375.436.0825.4693.5963.96
4810.3562.8754.7537.0497.4325.2364.2863.7643.5273.6584810.1611.3461.4337.3247.2126.977.0496.4194.2864.097
4820.522.9875.6268.2028.3465.6325.0184.2563.9844.174820.2541.8211.8358.498.3627.348.2027.4375.0184.526
4830.7453.0116.4828.5549.2316.3255.854.7694.5414.7164830.4022.1992.3259.8189.7238.459.4458.5545.855.141
4841.014.5637.6189.8489.6586.8926.8425.3765.1525.3934840.622.6272.95911.3510.3269.23410.839.8486.8425.728
4851.3594.6788.7411.313.2358.3467.9886.1025.8166.1224850.8753.0963.6813.0811.23510.2312.3911.37.7626.394
4861.8024.8799.94613.0415.579.2369.056.8126.5346.9054861.1583.5964.51115.1515.23614.2314.1813.048.6687.16
4872.3285.32611.4814.8515.68710.23610.37.6057.3597.7624871.4984.2865.47117.416.23615.23616.2214.8511.428.014
4882.9386.43213.1516.9318.32512.36211.818.4748.3118.6684881.9275.0186.61619.6218.23616.2318.2816.9313.258.936
4893.6167.45614.941919.54315.23613.359.4429.2199.6284892.4175.858.0482221.2520.4320.531915.949.855
4904.5129.45316.620.8921.115.89215.110.5110.2810.734902.9866.8429.63824.7424.53623.6522.8521.0818.35210.99
4915.45710.23418.4321.421.2518.32616.7511.5911.3611.914913.6087.98811.4127.6126.23525.3425.4823.2519.5412.18
4926.53112.47520.3522.5423.5421.23618.4612.8112.5913.124924.329.0513.530.5729.12628.5628.0225.8121.5313.35
4937.69714.57222.2623.4325.7121.32620.2713.9813.7714.244935.17410.315.6933.5531.23630.6530.728.3524.3514.6
4948.93715.567224.125.4327.8722.56