PMB = p-methoxybenzyl =

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Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep. First asymmetric total synthesis of aspinolide A. Tetrahedron Letters (2009), 50(50), 7018-7020.

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Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep. First asymmetric total synthesis of aspinolide A. Tetrahedron Letters (2009), 50(50), 7018-7020. PMB = p-methoxybenzyl =. DDQ =. Dichlorodicyanoquinone. Removal of p-methoxybenzyl protecting group. - PowerPoint PPT Presentation

Transcript of PMB = p-methoxybenzyl =

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Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep. First asymmetric total synthesis of aspinolide A. Tetrahedron Letters (2009), 50(50), 7018-7020.

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PMB = p-methoxybenzyl =

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DDQ =

Dichlorodicyanoquinone

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Removal of p-methoxybenzyl protecting group

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Removal of p-methoxybenzyl protecting group

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IBX = 2-iodoxybenzoic acid =

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IBX Mechanism

IBX is less soluble than the Dess-Martin Periodinane

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EDCI = Ethyl(dimethylaminopropyl)carbodiimide

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Carbodiimide Coupling Mechanism

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