Photon Counting Detectors for X-ray Imaging and Radiation ...

15
Photon Counting Detectors for X-ray Imaging and Radiation Therapy Joonas Tikkanen ab) , Teemu Siiskonen a) , Erik Brücken b) , Akiko Gädda b) , Vladyslav Litichevskyi b) , Stefanie Kirschenmann b) , Panja Luukka b) , Jennifer Ott b) , Alexander Winkler c) , Henri Petrow d) a) Radiation and Nuclear Safety Authority (STUK) b) Helsinki Institute of Physics (HIP) d) Detection Technology d) LUT University IDOS 2019 1821 June 2019, Vienna, Austria

Transcript of Photon Counting Detectors for X-ray Imaging and Radiation ...

Page 1: Photon Counting Detectors for X-ray Imaging and Radiation ...

Photon Counting Detectors for X-ray Imaging

and Radiation Therapy

Joonas Tikkanenab), Teemu Siiskonena), Erik Brückenb), Akiko Gäddab),

Vladyslav Litichevskyib), Stefanie Kirschenmannb), Panja Luukkab), Jennifer Ottb),

Alexander Winklerc), Henri Petrowd)

a) Radiation and Nuclear Safety Authority (STUK)b) Helsinki Institute of Physics (HIP) d) Detection Technologyd) LUT University

IDOS 201918–21 June 2019, Vienna, Austria

Page 2: Photon Counting Detectors for X-ray Imaging and Radiation ...

Background

• Currently, X-ray imaging detectors integrate

the dose in each pixel

– Photon energies not recorded

• Attenuation in the patient depends on the

photon energy

→ Better tissue separation with information of

energy spectrum

• For example: Dual energy computed

tomography (DECT)

– CT scans with two different tube voltages or

– Layered detectors

21.6.20192

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

https://doi.org/10.1016/j.nima.2017.04.014

Page 3: Photon Counting Detectors for X-ray Imaging and Radiation ...

Background

What if we could record the photon

energies in every pixel of an imaging

detector (photon counting detectors)?

• Attenuation of photons in multiple

energy regions

→ More information of the material

• Lower energy resolution, closer to

detection of mono-energetic photons

• Spectral information, “coloured” X-ray

images

• Higher contrast-to-noise ratio

→ Lower dose to patient

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

3

Page 4: Photon Counting Detectors for X-ray Imaging and Radiation ...

Background

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

4

Information from one pixelWhat if we could record the photon

energies in every pixel of an imaging

detector (photon counting detectors)?

• Attenuation of photons in multiple

energy regions

→ More information of the material

• Lower energy resolution, closer to

detection of mono-energetic photons

• Spectral information, “coloured” X-ray

images

• Higher contrast-to-noise ratio

→ Lower dose to patient

Page 5: Photon Counting Detectors for X-ray Imaging and Radiation ...

Background

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

5

What if we could record the photon

energies in every pixel of an imaging

detector (photon counting detectors)?

• Attenuation of photons in multiple

energy regions

→ More information of the material

• Lower energy resolution, closer to

detection of mono-energetic photons

• Spectral information, “coloured” X-ray

images

• Higher contrast-to-noise ratio

→ Lower dose to patient

Information from one pixel

Page 6: Photon Counting Detectors for X-ray Imaging and Radiation ...

Background

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

6

What if we could record the photon

energies in every pixel of an imaging

detector (photon counting detectors)?

• Attenuation of photons in multiple

energy regions

→ More information of the material

• Lower energy resolution, closer to

detection of mono-energetic photons

• Spectral information, “coloured” X-ray

images

• Higher contrast-to-noise ratio

→ Lower dose to patient

Information from one pixel

Page 7: Photon Counting Detectors for X-ray Imaging and Radiation ...

Background

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

7

What if we could record the photon

energies in every pixel of an imaging

detector (photon counting detectors)?

• Attenuation of photons in multiple

energy regions

→ More information of the material

• Lower energy resolution, closer to

detection of mono-energetic photons

• Spectral information, “coloured” X-ray

images

• Higher contrast-to-noise ratio

→ Lower dose to patient

Information from one pixel

Page 8: Photon Counting Detectors for X-ray Imaging and Radiation ...

Background

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

8

https://www.frontiersin.org/10.3389/conf.fbioe.2016.01.00902/event_abstract

What if we could record the photon

energies in every pixel of an imaging

detector (photon counting detectors)?

• Attenuation of photons in multiple

energy regions

→ More information of the material

• Lower energy resolution, closer to

detection of mono-energetic photons

• Spectral information, “coloured” X-ray

images

• Higher contrast-to-noise ratio

→ Lower dose to patient

Page 9: Photon Counting Detectors for X-ray Imaging and Radiation ...

Photon counting detector development

• Pixelated photon counting detectors being developed in

collaboration between Helsinki Institute of Physics, LUT

University, Aalto University and STUK

• Technologies based on a read out chip (ROC) developed for

the CMS experiment at CERN

– Pulse processing integrated into every pixel

– Spectral information

– Bump bonding to semiconductor wafer

• 100 x 150 µm2 pixel size

• CdTe (or CdZnTe) the main detector material under

investigation

• Other materials: thick silicon and combination of scintillator

and silicon

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

9

Page 10: Photon Counting Detectors for X-ray Imaging and Radiation ...

Cadmium Telluride

• Effective atomic number Zeff = 50: high absorption,

little scattering

– 84% of 60 keV photons are absorbed in 0.5 mm of

CdTe

– Electron range less than 50 µm at 100 keV

• 1.44 eV band gap

– Can be operated at room temperature

– Good energy resolution

• Disadvantages

– Brittle material, difficult to process

– Detector response variations due to material

inhomogeneity

– Limited availability

• Detector material QA with infrared spectrometry

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

10

https://www.5nplus.com/cadmium-telluride.html

CdTe defects

Page 11: Photon Counting Detectors for X-ray Imaging and Radiation ...

Measurements with CdTe

• Measurements with a 0.5 mm thick CdTe chip

at secondary standard dosimetry laboratory

of STUK

• A Cs-137 source was used

• 4160 pixels (52 x 80)

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

11

Page 12: Photon Counting Detectors for X-ray Imaging and Radiation ...

Measurements with CdTe

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

12

• 662 keV peak energy resolution approximately 2%

• Even response over the detector area

Page 13: Photon Counting Detectors for X-ray Imaging and Radiation ...

Scintillator enhanced silicon (SiS)

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

13

• Scintillator material on top of silicon pixel detector

• Silicon works both as a photodiode and detector

material

• Challenge: Pulses originating from scintillator slow

compared to Si induced pulses

• Plastic scintillators are faster but have a low atomic

number

• R&D in early stages

Page 14: Photon Counting Detectors for X-ray Imaging and Radiation ...

Radiation therapy dose profile measurements

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

14

• Thin silicon pixel detectors for dose profile measurements

• Application to high gradient dose profiles

– For example flattening filter free beams, IMRT, VMAT, small fields

• 3D dose distribution in a phantom by moving the detector

• Possible use of spectral information in correcting the detector response

Page 15: Photon Counting Detectors for X-ray Imaging and Radiation ...

Plans for the future

21.6.2019

Photon Counting Detectors for X-ray Imaging and Radiation Therapy, Joonas Tikkanen

15

• New CdTe detectors under characterization

• Tests in radiation beams

• Larger arrays (multiple chips and ROCs in one detector)

• Development of image processing algorithms

• Application to CT imaging

• Further development of SiS and silicon detectors

Picture of array here