Personalized therapy for cardiovascular disease
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Transcript of Personalized therapy for cardiovascular disease
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Mariana Velásquez CanoMedicine Student
Third semester
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Dalcetapib provides benefits for those who are suceptible to have heart attacks, strokes, unstable
angina, coronary revascularizations, cardiovascular deaths and curbing ateriosclerosis.
This study have determinated how the somiking of tobacco and consuming high fat food, will
induced a mutation that can promote cancer.
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Patients had to be with a genetic background to seek the correct
gene that promotes the desease.
The study showed that Dalcetrapib
will be a perzonalized
cardiovasculary medicine.
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The 39% represents the reduction of the risk factors to own in the future
one of this desease.
The study aims to the Most common heart illneses that cause
death in the world.
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Placebo was used to verified the efficiency of
dalcetrapib in any kind of patient, because placebo doesn’ t have any
chemist.
The investigators found the gene
(ADCY9 (adenylate cyclase
9) on chromosome 16,
through the result of the
medicament.
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Must people that suffers from
cardiovascular desease is
predisposed to have
aterosclerosis, the first cause of mortality in the
world. With dalcetrapib , the probably to get
it is lower.
This study will lead to a
genetics-guided clinical study in
patients with cardiovasculaty
desease.
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Smoking could lead to a damaged
on the DNA, causing a
mutacion, as cancer.
This type of genetic mutation
involves chemical
changes in the structure of
DNA.
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Adducts are types of DNA that result from exposure to carcinogens.
In this case, the people who are
exposed to tobacco and consuming
foods such as cured meats will have a damaged in DNA,
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.This study is an advange
of a possibility to expand DNA
sequencing including adducts.
The procedure of finding out where the
genetic code has been
altered into an adduct is
difficult and it has not been
possible.
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They made a negative copy of the genetic
material as a analogous to study
how DNA is replicated in naturally
cells.They produced
artificial derivatives of the basic DNA building blocks to
tested them as potential
counterparts to the alkylguanine.
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We can use DNA
investigations, to prevent, act, trate and cure.
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Is a base of a new
generation of discoveries
that will saved lives.
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Have a tratement for any disease exactly where
patients need it.
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Now that we know the cause and where is the
gene, we will know how to trate cancer and prevent it.
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• ·Montreal Heart Institute. Personalized therapy for cardiovascular disease. ScienceDaily [Internet] 2015 Jan [Fecha de acceso 22 enero de 2015]. Disponible en: www.sciencedaily.com/releases/2015/01/1500112181327,htm
• ETH Zurich. Damaged DNA amplified by activities such as smoking. ScienceDaily [Internet] 2015 Jan [Fecha de acceso 22 enero de 2015]. Disponible en: www.sciencedaily.com/releases/2015/01/150115102833.htm
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