Peritonitis MeSentEric by dr.S.H..

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    GIS-K-24

    PeritonitisMesenteric Lymphadenitis

    Syahbuddin Harahap

    Division of Digestive Surgery

    r ur ryFaculty of Medicine

    University of North Sumatera

    Adam Malik Hospital

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    Subdivisions :

    The greater sac

    The lesser sac (or omental )two "omenta":

    1. The lesser omentum(orgastrohepatic)

    .

    o

    (orgastrocolic)

    like an apron, protective

    layer.

    Greater sac and lesser sacConnected by the epiploic foramen

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    PeritonitisInflammation of the serosal membrane that lines theabdominal cavity and the organs contained thereinoften as a result of infection.

    Peritonitis are classified as :1. Primary peritonitis2. Secondary peritonitis

    3. Tertiary peritonitis

    Peritonitis are usually divided into

    1. Generalized peritonitis2. Localized peritonitis

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    Peritonitis is often caused by:

    - Perforation hollow viscus

    Etiology

    - (blood,pancreatic/gastic juice)

    - Infected / Inflammation

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    Primary peritonitis

    No pathologic process in a visceral organ

    Via hematogenous

    ChildrenTranslocation of bacteria across the gut wall

    Ascites

    n es n o s ruc onAscending infection in female

    Gonorrhea

    Chlamydial infection

    spreads into the abdominal cavity.

    Systemic infections tuberculosis

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    Secondary peritonitis

    Related to a pathologic process in a visceral organ

    hollow viscus- Perforation- Infected

    most common cause of eritonitis erforations of :

    - the stomach

    - intestine

    - gallbladder

    - appendix

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    Tertiary peritonitis

    Persistent or recurrent infection after adequate initial therapy

    Anastomotic leakage

    Abscess with or without fistulization.

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    Diagnosis and investigations

    Based primarily on clinical grounds

    No further investigation should delay surgery

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    Clinical:

    The diagnosis of peritonitis is usually clinical.

    1. Chief complaintAcute abdominal pain

    2. Peritoneal irritation Anorexia and nausea ,vomiting.

    .

    4. Hypovolemia Hypotensive

    5. Hypothermia severe sepsis Septic shock

    Peritonitis generally represents a surgical emergency.

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    On abdominal examination of Peritonitis

    1. Position/lighting/draping

    2. InspectionAbd. Distended Ileus paralyticusKeep their hips flexed to relieve the abdominal wall tension.

    3. Palpation all four quadrantsTenderness

    e oun en erness

    Diffuse Abdominal rigidity ("washboard abdomen")Abdominal Guarding voluntary in response of the abdominalInflammatory mass.

    4.Percussion

    Tenderness all four quadrantsPercuss the liver span free air

    5. AuscultationParalytic Ileus Hypoactive-to-absent bowel sounds.

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    6 . Digital rectal exam .Generalized peritonitis

    Tenderness in all direction

    AppendicitisTenderness in the right diection

    Female patients vaginal and bimanual examinationPelvic inflammatory disease

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    Mimic certain signs and symptoms of peritonitis.

    1. Thoracic processes with diaphragmatic irritation(eg, empyema)

    2. Extraperitoneal processes(eg, pyelonephritis, cystitis, acute urinary retention)

    3. Abdominal wall processes(eg, rectus hematoma)

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    WORKUP

    Lab Studies:

    Blood test

    leukocytosis (>11,000 cells/mL)

    Blood chemistry may reveal dehydration and acidosis.

    Liver function tests if clinically indicated

    Serum electrolytes

    Renal function Amylase and lipase if pancreatitis is suspected

    Urinalysis (UA) is essential to rule out urinary tract diseases (eg,

    pyelonephritis, renal stone disease Aerobic and anaerobic blood cultures

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    Complications

    Hypovolaemia shock-Sequestration offluid and electrolytes

    -Decreased central venous pressure

    Electrolyte disturbances

    Acute renal failure

    Peritoneal abscess

    Abdominal Sepsis may develop Septic shock

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    Radiographs

    Plain films of the abdomen :

    supineupright Free air

    Imaging Studies

    Computed tomography scanDiagnosis cannot be established on clinical grounds

    Cannot be findings on abdominal plain films.

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    Mesenteric Lymphadenitis

    1. Inflammation of the mesenteric lymph nodes.2. Acute or chronic, depending on the causative agent.3. Often difficult to differentiate from acute appendicitis.

    PathophysiologyMicrobial agents are thought to gain access to the lymphnodes via the intestinal lymphatics.

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    Clinical

    Clinical features of associated organ involvement, such asenterocolitis or ileitisAbdominal pain - Often right lower quadrant (RLQ) but may

    be more diffuseFeverDiarrheaMalaise

    AnorexiaUpper respiratory tract infectionNausea and vomiting

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    Physical

    Fever (38-38.5C)RLQ tenderness - Mild, with or without rebound

    tendernessRectal tendernessRhinorrhea

    Hyperemic pharynxAssociated peripheral lymphadenopathy (usuallycervical) in 20% of cases

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    Causes

    Streptococcus beta-hemolytic,Staphylococcusspecies,Escherichia coliStreptococcus viridans,

    Mycobacterium tuberculosis,Viruses, such as coxsackieviruses, rubeola virus, andadenovirus

    Children with upper respiratory tract infection, haspopularized a theory that swallowed pathogen-laden sputummay be the primary source of infection.

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    Lab StudiesCBC countLeucocytosis exceeding 10,000/L

    Urinalysis exclude urinary tract infection.

    Stool cultures Diarrheal symptoms

    Blood culture Septicemia

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    Imaging Studies

    CT scanning

    In mesenteric adenitis: lymph nodes to be larger

    CT scanning is also important to excludeother differential diagnoses, especially acuteappendicitis.

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    Medical Care

    Hemodinamic support

    Broad-spectrum antibiotics

    Surgical Care

    Signs of peritonitis

    Appendectomy