Session 3

Peer Support Quiz

Ligands that activate a pathway are called?

Ligands that activate a pathway are called?

Agonists

Oppositely, ligands that deactivate a pathway are called antagonists

How many subunits in a G-protein?

How many subunits in a G-protein?

Three• Alpha α• Beta β• Gamma γ

Name the 3 doctor-patient relationships.

Name the 3 doctor-patient relationships.

• Paternalistic• Shared• Informed

Saliva is produced from which cells?

Saliva is produced from which cells?

Acini cells

What are the 4 main definitions of health?

What are the 4 main definitions of health?

• Health is absence of illness - -ve• Health is functional ability - -ve• Health is freedom - +ve• Health is equilibrium- +ve

Nitric oxide works with guanylate cyclase through which cyclic nucleotide?

Nitric oxide works with guanylate cyclase through which cyclic nucleotide?

cGMP

G-proteins are switched ‘ON’ when bound to GDP.True or False

G-proteins are switched ‘ON’ when bound to GDP.True or False

False G-proteins must be bound to GTP to be

active

What are the 4 roles of saliva?

What are the 4 roles of saliva?

•Solvent •Lubrication•Digestion•Protection

What are the 4 main stages in the signalling cascade for growth factors (GF)?

What are the 4 main stages in the signalling cascade for growth factors (GF)?

• Binding of GF stimulates dimerisation of receptors

• Phosphorylation of receptors• Ras and adaptor bind• Ras GDP GTP nucleotide exchange

What is the typical ion concentration of potassium K+ inside and outside the cell?

What is the typical ion concentration of potassium K+ inside and outside the cell?

Inside = 160mMOutside = 5mM

Inhibitory growth factor IGF works through which target proteins?

Inhibitory growth factor IGF works through which target proteins?

SMADs

Chronic illness can impact on a persons life in which 4 ways?

Chronic illness can impact on a persons life in which 4 ways?

• Daily living• Social relationships• Identity (how others view them)• Sense of self (how they view themselves)

Saliva excretion is controlled by which nervous system?

Saliva excretion is controlled by which nervous system?

Parasympathetic

DFLE stands for? (in the context of life expectancy)

DFLE stands for? (in the context of life expectancy)

Disease free life expectancy

Name the 3 phases of swallowing?

Name the 3 phases of swallowing?

•Oral •Pharyngeal •Oesophageal

How can you measure socio-economic status?

How can you measure socio-economic status?

•Occupation•Education•Ownership/access to assets

Name 5 originations of lay beliefs.

Name 5 originations of lay beliefs.

• Personal knowledge or experience• Previous encounters• Folk knowledge• Media/internet• Spiritual beliefs • Alternative and complementary medicine

What 3 mechanisms can change cell behaviour?

What 3 mechanisms can change cell behaviour?

• Gene transcription • Altered ion balance across the plasma

membrane• Altered activity/level of pre-existing

enzymes

Is the lower oesophageal sphincter a true sphincter or a physiological one?

Is the lower oesophageal sphincter a true sphincter or a physiological one?

Physiological

Give 3 outcomes of shared decision making.

Give 3 outcomes of shared decision making.

•Improve patient outcome•Reduction in costs•Increased patient satisfaction

PLC hydrolyses PIP2 to what?

PLC hydrolyses PIP2 to what?

IP3 and DAG

What are the 5 triggers for seeking medical help?

What are the 5 triggers for seeking medical help?

• Interpersonal crisis• Interference with social or personal

relationships• Sanctioning• Interference with vocational or physical

activity• Temporalisation of symptomatology

List the 5 types of receptor.

List the 5 types of receptor.

•Intracellular•Ion channel•Intrinsic enzyme activity •Soluble protein kinase•Linked to a G-protein

What are the concentrations of Ca2+ ions inside and outside of the cell?

What are the concentrations of Ca2+ ions inside and outside of the cell?

Inside = 0.2μMOutside = 2mM

Remember – its an increase in concentration of x10,000

For a nucleotide to be a second messenger, it must be in a cyclic form.True or false

For a nucleotide to be a second messenger, it must be in a cyclic form.True or false

True