Paulo Santos ppt · 2017. 2. 1. · Dyspepsia: an underestimated problem among end-stage renal...
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Dyspepsia: an underestimated problem among end-stage renal disease patients Paulo Santos Federal University of Ceará, Brazil
Transcript of Paulo Santos ppt · 2017. 2. 1. · Dyspepsia: an underestimated problem among end-stage renal...
Dyspepsia: an underestimated problem
among end-stage renal disease patients
Paulo SantosFederal University of Ceará, Brazil
Highly prevalent
Great impact on quality of life
Prevalence
In the literature:
between 50% and 70%50% 70%VanVlem et al Am J Kidney Dis 2000; 36:962
Cano et al Am J Gastroenterol 2007 102:1990
Impact on Quality of Life
50
60
70
80
90
0
10
20
30
40
50
PF RP BP GH VIT SF RE MH
Non-dyspeptics
Dyspeptics
Santos et al. Brazilian Congress of
Nephrology 2012
What is dyspepsia?
• Constellation of symptoms
– Upper abdominal pain; Nausea; Vomiting; Upper
abdominal bloating; Early satietyabdominal bloating; Early satiety
• Tack et al. Gastroenterology 2006; 130:1466
WHY?
I. Gastric emptying delay
II. Hypervolemia
WHY?
I. Gastric emptying delay
II. Hypervolemia
Clinical implications
I. It is very easy to search for symptoms of
dyspepsia, so it should be done often
II. Our finding raises the question about the
main role of prokinetics in dyspepsia cases
WHY?
I. Gastric emptying delay
II. Hypervolemia
WHY?
I. Gastric emptying delay
II. Hypervolemia
Volemic status
Clinical implications
I. Functional dyspepsia could be an alert of the
need to revise the prescribed dry-weight of
patients on HDpatients on HD
II. Dyspeptic symptoms could be another tool
to help estimate the optimal dry weight of
patients on HD
IMPACTS ON NUTRITIONAL STATUS?
Clinical implication
I. Screening of dyspeptic symptoms can be
used as a tool for identification of patients used as a tool for identification of patients
on HD who are at risk of malnutrition
