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1 Patient Information Leaflet P1 Parathyroid Operations in Adults What are the Parathyroid glands and what do they do? Usually, you have four parathyroid glands. These are located between the thyroid gland and the windpipe, two on each side. In healthy adults, each parathyroid gland is usually 3-4 mm in size. They are responsible for the secretion of a hormone (the parathyroid hormone, PTH) which is required for the regulation of calcium in the body. Recurrent Laryngeal nerve ‘Voice nerve’ Thyroid gland Parathyroid glands Clavicle Collar boneSternum ‘Breast boneSuperior Laryngeal nerve Larynx Adam’s appleReasons why patients may need parathyroid surgery One common cause of high calcium in the body is due to an abnormal parathyroid gland which is ‘over-functioning’ and producing too much PTH. In the majority of patients, this is due to a single abnormal parathyroid gland (Primary Hyperparathyroidism). In some instances, more than one gland is involved.

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PatientInformationLeafletP1

ParathyroidOperationsinAdults

WhataretheParathyroidglandsandwhatdotheydo?Usually,youhavefourparathyroidglands.Thesearelocatedbetweenthethyroidglandandthewindpipe,twooneachside.Inhealthyadults,eachparathyroidglandisusually3-4mminsize.Theyareresponsibleforthesecretionofahormone(theparathyroidhormone,PTH)whichisrequiredfortheregulationofcalciuminthebody.

RecurrentLaryngealnerve‘Voicenerve’

Thyroidgland

Parathyroidglands

Clavicle‘Collarbone’

Sternum‘Breastbone’

SuperiorLaryngealnerve

Larynx’Adam’sapple’

ReasonswhypatientsmayneedparathyroidsurgeryOnecommoncauseofhighcalciuminthebodyisduetoanabnormalparathyroidglandwhichis‘over-functioning’andproducingtoomuchPTH.Inthemajorityofpatients,thisisduetoasingleabnormalparathyroidgland(PrimaryHyperparathyroidism).Insomeinstances,morethanoneglandisinvolved.

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PTHactsonthekidneys,boneandgastrointestinaltract(stomachandbowel)toincreasethecalciumintheblood.Althoughhighcalciummaybeassociatedwithsymptoms,manypatientshavetheirhighcalciumdetectedcoincidentallyonroutinebloodtests.Symptomsthatmaybeassociatedwithhighcalciumcaninclude:

• muscleweaknessandfatigue• changesinyourheartrate• weightloss• excessivethirst• changesinurinaryfrequency• dehydration• stomachulcers• kidneystones• fractures

Eveninpatientswhodonothavesymptomsduetohighcalcium,parathyroidsurgeryisrecommended,assurgerydecreasesthelong-termeffectsonthebonesandkidneys.Whatarethealternativestosurgery?Medicationdoesexisttocontrolthehighcalciumintheblood.Youmayalreadyhavediscussedtheseoptionswithyourendocrinologistpriortoreferraltothesurgicalclinic.Medicaltreatmentisgenerallyoftemporarybenefit,anddoesnotaddresstheunderlyingproblemoftheoveractiveparathyroidgland.WhattestswouldIexpecttohavebeforesurgery?Priortoreferraltothesurgicalclinic,bloodandurinetestsarelikelytohavebeenperformedbyyourendocrinologist.Inadditiontothis,allpatientswouldneedtohaveanultrasoundscanoftheneckandkidneys.AspecializedscancalledtheSestamibiscanwouldalsoberequiredinthemajorityofcircumstances.Fortheminorityofpatients,aCTscanoranMRIscanmayberequired.WhattypeofparathyroidoperationsshouldIexpect?Theoperationisperformedunderageneralanaestheticsoyouarecompletely‘asleep’.

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Therearegenerally2approachestoparathyroidsurgeryOpenOperationAlsocalledcervicalexplorationorbilateralneckexploration.Thesurgeonwillmakeasmallincision(5to7cmor2to3inches)inyourneckinordertoperformthesurgery.Theadvantageofthistypeofsurgerywouldbetoensurethatallfourparathyroidglandsareinspected,andthediseasedglandisremoved.FocusedOperationAlsoknownasminimallyinvasiveapproachorkeyholeapproach.Theuseofthepreoperativescanshasallowedmoreaccurateidentificationofthediseasedparathyroidglandinsomepatients.Thus,inthesepatientsasmallerscarcanbeused.Onlytheglandidentifiedtobediseasedonthescan(s)isremoved.Yoursurgeonwillexplainwhichoneyouareadvisedtoconsiderandwhy.Inbothcases,thewoundisthenstitchedwithdissolvingstitchesorremovablestitches.Itwillhealtoformascar.Whatwillhappenpriortosurgery?Ifyouareonregularmedications,youshouldcontinuetheseunlessadvisedotherwise.Somesurgeonsmayaskyoutostoptakingmedicinessuchasaspirin,dipyridamole(Persantine)orclopidogrel(Plavix)inthedaysleadinguptoyouroperation.Ifyouareonanyofthesetablets,discussthiswithyoursurgeon.Patientsonblood-thinningtablets(suchaswarfarin,rivaroxabanordabigatran)shouldinformtheirsurgeon.HowlongwillIbeinhospital?Thisdependsverymuchonwhatprocedureyouhadandthehospital’slocalpolicies.Yoursurgeonwilladviseyouaccordingly.CareofyourwoundWhenyouaredischargedfromhospitalyoucanexpecttobegivenadviceaboutcareofyourwoundfromthewardstaff.Thewoundmaybecoveredbyadressingandthiscanusuallyberemovedafter48hoursunlessyouaretold

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otherwise.Youwillusuallybeabletotakeabathorshower48hoursafteryouroperation.Gentlypatyourwounddryratherthanrubit.Yourwoundmaybeslightlyraisedandpinkorredinthedaysfollowingsurgery.Thiswillsettleovertimeasitheals.Eventuallythewoundshouldbecomeflatandpalebutthismaytakeseveralmonths.Unlesssuggestedbyyourmedicalteam,itisnotadvisabletorubanyointmentsorbio-oilsontothewoundimmediatelyafteryoursurgerybeforethewoundhashadchancetoheal.Itisbesttowaituntilyouhavebeenseeninthepost-operativeclinicanddiscusswithyoursurgeonifyouwishtousesuchproducts.WhatcanIexpectaftertheoperation,andhowsoonwillIrecover?Itisnormaltofeeltiredfollowingparathyroidsurgery.Thesymptomsoftirednessthatyoumayhavehadpre-operativelymaytakeafewweekstoresolve.Insomecases,followingparathyroidsurgery,thelevelsofcalciuminyourbloodcanfalltoolow.Thisiswhilethebodyregainscontrolofcalciumbalanceinyourbloodstream.Yoursurgicalteamwillcheckforthisonpostoperativebloodtestsandyoumaybeprescribedcalciumtabletsshouldtheselevelsfalltoolow.Ifyoufeeltinglingorspasmsinyourlips,fingersortoes,contactyourGPasthiscanbeasignthatyourbloodcalciummayhavefallentoolow.Followinganeckexploration,youshouldbeabletoeatanddrinknormally,butsomepatientsfeelasthoughthereisalumpintheirthroatastheyswallow.Thisiscommonandwilldisappearintime.Beforeresumingdrivingyouneedtoensurethatyoucanmakeanemergencystopwithouthurtingyourneck.Youalsoneedtobeabletocomfortablyturnyournecktolookaroundasyoudrive,forexample,whenyouchangelanes.Youshouldinformyourcarinsurancecompanythatyouhavehadaparathyroidoperationasdifferentinsurersmayhavetheirownrulesabouthowlongyoushouldwaitafteranoperationbeforeyoureturntodriving.Yourreturntoworkdependsonthetypeofworkyoudoandtheoperationyouhavehad.Youmaybeabletoreturntooffice-basedworkaftertwotothreeweeksandheavierworkafterfourweeks.Yoursurgicalteamwilladviseyou.

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Whatarethepossiblecomplicationsofparathyroidsurgery?Complicationsofparathyroidsurgeryareuncommon.Thevastmajorityofpatientshavestraightforwardsurgeryandaredischargedthefollowingdaywithoutanycomplications.Yoursurgeonwilldiscussthebenefitsandpotentialcomplicationsofsurgerywithyouindetail.Pleasefeelfreetoaskanyquestionsthatareonyourmind.BAETShaveproducedapatientinformationleaflet,PotentialConsequencesofParathyroidSurgery,whichcanbefoundonourwebsite(www.baets.org.uk).

BAETSwishestoacknowledgetheadviceandsupportofHypoparaUK,apatient

supportgroupthatsupportspatientswhohavepostoperativeparathyroid

problems.

ForfurtherinformationandsupportpleasevisitHypoparaUKat

www.hypopara.org.ukorcall01342316315/01623750330

Disclaimer

Theadviceinthisleafletisbelievedtobetrueandaccurateatthetimeofgoingtopress.

Ultimately,theresponsibilityforobtaininginformedconsentfromyouforasurgicalprocedure

lieswithyoursurgicalteamandnotwiththeBritishAssociationofEndocrine&Thyroid

Surgeons(BAETS).

BAETScannotacceptanylegalresponsibilityforthecontentsofthisleafletwhichisproducedin

goodfaith.