Pathway Sepsis

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Faktor Mikrobiologi Bakteri Masuk kedalam tubuh Infasi Bakteri dan kontaminasi sistemik Infeksi Bakteremia dan Septikemia Pelepasan Endotoksin Leukosit Resiko Infeksi Kegagalan mikrosirkulasi ke otot Jantung Disfungsi Mikrosirkulasi Meransang Sintesa dan Pelepasan zat pirogen oleh leukosit Sepsis Sistem Kardiovaskuler Zat Pirogen Beredar dalam darah Iskemia Otot Ekstrasi O2 Ke jaringan Hipoksia Sel Faktor Host

description

sepsis

Transcript of Pathway Sepsis

Page 1: Pathway Sepsis

Faktor Mikrobiologi

Bakteri Masuk kedalam tubuh

Infasi Bakteri dan kontaminasi sistemik

Infeksi

Bakteremia dan Septikemia

Pelepasan Endotoksin

Leukosit Resiko Infeksi

Kegagalan mikrosirkulasi ke otot Jantung

Disfungsi Mikrosirkulasi

Meransang Sintesa dan Pelepasan zat pirogen oleh leukosit

Sepsis

Sistem Kardiovaskuler

Zat Pirogen Beredar dalam darahIskemia Otot

Ekstrasi O2 Ke jaringan

Terjadi mekanisme kompensasi tubuh untuk meningkatkan intake O2 dengan Frekuensi Napas

Pompa jantung tidak adekuat Aktivasi ProstaglandinKegagalan respon terhadap kebutuhan O2

Hipoksia Sel

Faktor Host

Page 2: Pathway Sepsis

Kegagalan kontrol aliran darah lokal

Saturasi oksigen

Pelepasan nitrit oksida

Vasodilatasi kapiler

Mendistribusi volume darah

Hipoperfusi jaringan

Respiration Rate

Ketidak efektifan pola nafas

Limfosit T mengeluarkan substansi Th1 dan Th2

Adhesi neutrofil dengan endotel

Dinding endotel lisis

Kerusakan endotel pembuluh darah

Cairan intravaskuler keluar ke interstitial

Penurunan volume darah intravaskuler

Prostaglandin mempengaruhi pusat thermoregulasi di hipotalamus

Hipotalamus set poin suhu

Suhu tubuh diatas kisaran normal

Hipertermi

Penurunan curah jantung

Hipoperfusi perifer

Resiko syok


 · MOAcc. um. C , JM. in J pathway ... pathway) enter sepsis pathway : CBC w/diff. CMP. LacticAcid. acx2. cxR. Consider other cultures and studies (LP, viral assays ...

 · MOAcc. um. C , JM. in J pathway ... pathway) enter sepsis pathway : CBC w/diff. CMP. LacticAcid. acx2. cxR. Consider other cultures and studies (LP, viral assays ...

Sepsis Recognition & Response - Sepsis Pathway Education

Sepsis Recognition & Response - Sepsis Pathway Education

Adult Sepsis Pathway - WSLHD

Adult Sepsis Pathway - WSLHD

LVHN Sepsis Quality Improvement ProjectThe Sepsis Pathway Severe Sepsis Non-Invasive Protocol SIRS + confirmed infection + one organ system dysfunction 2 LB IV 30 cc/kg NSS over 1

LVHN Sepsis Quality Improvement ProjectThe Sepsis Pathway Severe Sepsis Non-Invasive Protocol SIRS + confirmed infection + one organ system dysfunction 2 LB IV 30 cc/kg NSS over 1

Sepsis: developing a regional pathway and a standardised ... · From confusion to consensus: The Oxford AHSN Sepsis Pathway Andrew Brent Sepsis Clinical Lead, Oxford AHSN & Oxford

Sepsis: developing a regional pathway and a standardised ... · From confusion to consensus: The Oxford AHSN Sepsis Pathway Andrew Brent Sepsis Clinical Lead, Oxford AHSN & Oxford

Maternal Sepsis - sepsiscoordinatornetwork.org · •The normal physiological changes may mask early signs of sepsis ... Postpartum • Retained ... Maternal Sepsis Pathway Screen

Maternal Sepsis - sepsiscoordinatornetwork.org · •The normal physiological changes may mask early signs of sepsis ... Postpartum • Retained ... Maternal Sepsis Pathway Screen

Sepsis Overview - SMLC · Typical Sepsis Care Pathway -70% Patient presents at point of entry Initial triage indicates possible infection (ED) CBC-Diff BMP UA ordered Sepsis evaluation

Sepsis Overview - SMLC · Typical Sepsis Care Pathway -70% Patient presents at point of entry Initial triage indicates possible infection (ED) CBC-Diff BMP UA ordered Sepsis evaluation

Infants and Children: Acute Management of Altered ... · Paediatric Sepsis Pathway . 3. If bacterial meningitis rather than sepsis is the likely diagnosis, refer to . Infants and

Infants and Children: Acute Management of Altered ... · Paediatric Sepsis Pathway . 3. If bacterial meningitis rather than sepsis is the likely diagnosis, refer to . Infants and

Emergency Department Adult Sepsis Clinical Pathway · Web viewEmergency Department, Sepsis, clinical pathway, Disclaimer This document has been developed by ACT Health, Canberra Hospital

Emergency Department Adult Sepsis Clinical Pathway · Web viewEmergency Department, Sepsis, clinical pathway, Disclaimer This document has been developed by ACT Health, Canberra Hospital

Newborn Antibiotic Guideline for Early and Late Onset of ...€¦ · Newborn meets sepsis pathway criteria Further management: The newborn with presumed or suspected sepsis must be

Newborn Antibiotic Guideline for Early and Late Onset of ...€¦ · Newborn meets sepsis pathway criteria Further management: The newborn with presumed or suspected sepsis must be

Sexing up the Sepsis Six - Acute Medicine - sexing... · Sexing up the Sepsis Six ... Sepsis Six Pathway EWS greater than 3 OR clinical suspicion of infection? ... SpO 2 less than

Sexing up the Sepsis Six - Acute Medicine - sexing... · Sexing up the Sepsis Six ... Sepsis Six Pathway EWS greater than 3 OR clinical suspicion of infection? ... SpO 2 less than

Sepsis ACP 2019 · • Often difficult to identify sepsis patients early; disease may be indistinguishable from many other conditions. Therefore, many patients are place in this pathway

Sepsis ACP 2019 · • Often difficult to identify sepsis patients early; disease may be indistinguishable from many other conditions. Therefore, many patients are place in this pathway

Implementation of an Inpatient Pediatric Sepsis Identification Pathway · Implementation of an Inpatient Pediatric Sepsis Identification Pathway Chanda Bradshaw, MD, Ilyssa Goodman,

Implementation of an Inpatient Pediatric Sepsis Identification Pathway · Implementation of an Inpatient Pediatric Sepsis Identification Pathway Chanda Bradshaw, MD, Ilyssa Goodman,

Sepsis-associated Pathways Segregate Cancer Groups · Keywords: Sepsis, Septic shock, Cancer, KEGG Pathway, TCGA, GEO Background Sepsis is a potentially life-threatening complication

Sepsis-associated Pathways Segregate Cancer Groups · Keywords: Sepsis, Septic shock, Cancer, KEGG Pathway, TCGA, GEO Background Sepsis is a potentially life-threatening complication

Sepsis Pathway 12515

Sepsis Pathway 12515

Untitled-13.html - safetyandquality.gov.au  · Web viewAdult sepsis pathway. Sydney. ACI, 2011. Used in the NSW CEC Sepsis Kills program.c ... hernia repair. burns, extensive skin

Untitled-13.html - safetyandquality.gov.au  · Web viewAdult sepsis pathway. Sydney. ACI, 2011. Used in the NSW CEC Sepsis Kills program.c ... hernia repair. burns, extensive skin

I Screen, You Screen, We All Screen for Sepsis! 020917_508.pdfIf ≥5, initiate Sepsis Pathway If ≥5, initiate Severe Sepsis Protocol. PROCESS 24 Sepsis Flowchart ER Primary Screen

I Screen, You Screen, We All Screen for Sepsis! 020917_508.pdfIf ≥5, initiate Sepsis Pathway If ≥5, initiate Severe Sepsis Protocol. PROCESS 24 Sepsis Flowchart ER Primary Screen

sepsis sepsis sepsis sepsis

sepsis sepsis sepsis sepsis

Admit Sepsis Plan - Begin Immediately - Lubbock, Texasapps.umchealthsystem.com/forphysicians/medicalorders/pathway... · Admit Sepsis Plan - Begin Immediately ... Empty the contents

Admit Sepsis Plan - Begin Immediately - Lubbock, Texasapps.umchealthsystem.com/forphysicians/medicalorders/pathway... · Admit Sepsis Plan - Begin Immediately ... Empty the contents

Influence of roflumilast on sepsis mice through the JAK ... · tissue morphology of sepsis mice by inhibiting the JAK/STAT signaling pathway. Key Words Sepsis, Inflammation, Roflumilast,

Influence of roflumilast on sepsis mice through the JAK ... · tissue morphology of sepsis mice by inhibiting the JAK/STAT signaling pathway. Key Words Sepsis, Inflammation, Roflumilast,