PATHOLOGY OF THE

FEMALE GENITAL TRACT II,

PATHOLOGY OF BREAST

X. practical training

3rd year General Medicine

Cervical polyp

Condyloma accuminatum of the vulva

Transformation zone

Cervical squamous neoplasia

Cervical

carcinoma

Poorly differentiated (nonkeratinizing)

squamous cell carcinoma of the cervix

Poorly differentiated (nonkeratinizing)

squamous cell carcinoma of the cervix

Endometrium, cyclus

1 2 3 4 1 early

proliferation

2 late

proliferation

3 early secretion

4 late secretion

Hyperplastic endometrium

1 Hyperplastic endometrium

2 Polypous endometrial hyperplasia

1 1

2

Dysfunctional hyperplastic proliferative

endometrium

Leiomyoma of the uterus

2

1

3

2

1 Subserous myoma

2 Intramural myoma

3 Submucous myoma

4 „born“ submucous myoma

4

Leiomyoma of the uterus copy

Leiomyoma of the uterus

Leiomyoma Leiomyosarcoma

1 1

1

Mitosis copy

Uterine corpus

carcinoma

Uterine corpus

carcinoma

Adenokarcinom (endometroidní) těla děložního

Residua post abortum

Hydatidiform mole

Hydatidiform mole

1

2

1 Edematózní bezcévné klky

2 Povrchová část klků

Hydatidiform mole

Chorionepithelioma (choriocarcinoma)

Ectopic (tubal) pregnancy

1

2

3

4

5

6

7

1 Serosis of tube

2 Wall of tube -

muscularis propria

3 Mucosal villi

4 Columnar epithelium

of tube

5 Coagulated haematoma

6 Hydropic degenera

tion of chorionic villi

7 Cytotrofoblastic cells

Abnormalities in

breast

development

Fibrocystic

disease

Fibrocystic disease

Fibrocystic disease

Histologic grading of mammary carcinomas

Body

1 Duct formation > 75% of the tumour 1

10 – 75% of the tumour 2

< 10% of the tumour 3

2 Nuclear atypia uniforme nuclei 1

small variability 2

large nuclei, marked atypia 3

3 Mitotic activity 0 - 8 MF 1

(2,5 mm2, 5 HPF) 9 – 17 MF 2

18 and more MF 3

score 3-5 = grade 1, score 6-7 = grade 2, score 8-9 = grade 3

Breast fibroadenoma

Breast

carcinoma

Commedocarcinoma (IDC)