Since the founding of the Johns HopkinsHospital in 1889 and the Medical School

four years later, the history and accomplish-ments of the Department of Pathology havebeen impressive. The first Professor andDirector of Pathology was Dr. William We l c h

• Sanfilippo Portrait

• Continuing Education Courses

• New Graduate Students

• 3rd Annual Young Investigator’s Day

• The Tecan is Coming!

• Dorothy Reed Mendenhall

• Funding our Future

• New House Staff

• New Professorship in Urologic Path

• Faculty Changes

• New Grants and Contract Aw a r d s

• On the Web

• Pathology Calendar

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Inside...whose influence on the School of Medicine,the School of Hygiene, and the Hospitalremains unsurpassed. The tradition of con-ducting outstanding research, teaching, andservice started by Dr. Welch have hadtremendous national and internationalimpact on the diagnosis, treatment, andunderstanding of the pathogenesis of anumber of diseases. This tradition has beenmaintained and strengthened by successiveDirectors: William G. MacCallum 1917-1944, Arnold R. Rich (1947-1958), Ivan L.Bennett, Jr (1958-1969), Robert H.Heptinstall (1969-1988), John H. Ya r d l e y(1988-1992), and Fred Sanfilippo (1993-2000). I am greatly honored and privilegedto have been appointed the 8th BaxleyProfessor and Director of Pathology as of

Director’s CornerJ. Brooks Jackson, M.D., M.B.A.

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In the fall of 2000 the Directors of the CoreLaboratory and the Pathology Administrators,

in an effort to respond to the limited staff avail-ability and the institutional financial pressures,identified similarities between the CoreLaboratory and the outreach laboratories suchas Express Testing and Green Spring Station.These synergies offered an opportunity to createan integrated Core Laboratory that includesoutreach services.

The first step was to create a managementstructure under a single Assistant Administrator.Al Valentine was selected to oversee the newlystructured operation. Working with a team ofsupervisors, they developed an organizationalstrategy that grouped the new operational divi-sion into three areas: Pre/Post Analytical,Analytical, and Technical Support.

Headed by Mike Huppenthal the Pre/PostAnalytical area encompasses Inpatient

P h l e b o t o m y, Internal and ExternalTransportation (Lois Tissue), SpecimenProcessing (Denise Gingher), Customer Service(Bill Hartlove), Green Spring Station, WhiteMarsh (Ellen Dumer), Johns HopkinsCommunity Physicians, Johns Hopkins HomeCare, Baltimore Medical System, and KennedyKrieger (LaVerne Farrar).

Greg Gerhardt (Chemistry), Mary Jo Bill(Special Chemistry), Inge Hobbs (Hematology),Lydia Nelson (Evening Shift), and ScottRatchford (Overnight Shift) supervise theAnalytic areas. This team oversees the clinicaloperations in Core Chemistry, Core Hematology,Special Chemistry, To x i c o l o g y, EmergencyRoom Lab, Critical Care Lab, Weinberg Lab,Special Coagulation, Flow Cytometry, andMolecular Hematology.

The Technical Support group monitorsand assists with functions such as Chemistry

Path WaysThe Johns Hopkins Medical Institutions Department of Pathology Volume 5, Issue 2, Fall, 2001

Division in Highlight: The New “Non” Core LaboratoryQC, Hematology QC, Divisional QA, Education,Staff Development, Safety, and Near PatientTesting (Waived and Non-waived). SandyHumbertson oversees a staff of specialists whoassist with these responsibilities.

The Core Laboratory is a multi-disciplinelaboratory located in several areas with many ofthe laboratories open 24/7. Leadership realizedthat there was no one major project whichcould bring efficiencies and stress relief to itsstaff. Therefore, the management team focusedon individual opportunities in each of the areas.

Twenty-four hour phlebotomy was trans-ferred from the Department of Nursing toPathology in December 2000. The current serv-ice as viewed by Nursing and Physicians hasimproved greatly. Phlebotomy supervisors areworking with nurse managers to identify pat-terns of redundant ordering. A program is cur-rently in place to facilitate licensure of the

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Dr. J. Brooks Jackson

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Hopkins is a place where the past isimportant. And in boardrooms, lec-

ture halls and administrative officesthroughout the campus, the past staresdown at us in the form of portraits ofour leaders of earlier eras. With thedeparture or retirement of each director,departments traditionally commission aportrait to add to the Hopkins collection.This year, we commemorated the tenureof Dr. Fred Sanfilippo with such a por-trait, so that it joins those of previousBaxley Professors and Directors ofPathology dating back to WilliamWe l c h .

D r. Sanfilippo’s portrait was paint-ed by Peter Egeli, a native of SouthernMaryland, and a renowned painter ofportraits, landscapes, and marine sub-jects. He has had the opportunity to paint por-traits of notable individuals from all sectors ofi n d u s t r y, government and academia. He has aparticular gift for making his subjects revealthemselves to him so he can capture theiressence in a lifelike portrait. He has had nearlytwo dozen portraits commissioned by JohnsHopkins, including those of WilliamRichardson, Daniel Nathans, Morris Offit,Harvey Meyerhoff, Patrick Walsh and DonaldC o f f e y.

was preceded by a short presentation by afaculty colleague describing the honoree’scareer at Hopkins; in Dr. Jackson’s absenceI had the honor of making this presenta-tion for Dr. Sanfilippo. Frankly, I foundthe task of recounting Fred’s numerousaccomplishments for the department aneasy and pleasurable one. Dr. Sanfilippoand his wife Janet were able to make thetrip from Columbus for the unveiling, andI know both were thrilled with Mr. Egeli’swork, and honored by the ceremony. Itwas the consensus of everyone I spoke withthat Dr. Sanfilippo’s was the best portraitthere (of course everyone I spoke with wasfrom pathology).Although the painting was officiallyunveiled at the biennial, many received a

sneak preview of the painting when it waspresented to the Department at the annual resi-dent and fellow awards dinner on June 1st. Forthose who haven’t yet had the opportunity to seeit, it will be displayed prominently in theadministrative offices in Carnegie Bldg. 417.Come by and have a look and see what a greatjob Mr. Egeli did capturing Dr. Sanfilippo forp o s t e r i t y.

Michael J. Borowitz, M.D., Ph.D.

The portrait was officially unveiled onJune 8, at the biennial meeting of the HopkinsMedical Alumni. The unveiling ceremony waspresided over by Dr. William Brody, President ofJohns Hopkins University, and also featured thepresentation of portraits of Drs. Edward Benz ofMedicine, Charles Cummings ofO t o l a r y n g o l o g y, Daniel Drachman ofN e u r o l o g y, Donnell Long of Neurosurgery, PaulMcHugh of Psychiatry, and Edward Miller ofA n e s t h e s i o l o g y. The unveiling of each portrait

Sanfilippo Portrait

left to right, Janet Sanfilippo, Dr. Fred Sanfilippo, and Dr. Michael Borowitz

September 1, 2001. It is especially gratifyingto know that I have such strong supportfrom so many of the faculty and staff whomI admire and respect within and outside theDepartment. I thank you for your support.

My goal over the next 5 years is to con-tinue this tradition of excellence and expandthe scope of our research, teaching, andservice activities within Johns HopkinsMedicine at home and abroad. In terms ofservice, we must be able to support theexpanding patient care activities of JohnsHopkins Medicine locally and international-l y. Priorities will include the integration ofpathology services across Johns HopkinsMedicine and the expansion of the outsidediagnostic consult service, our test menu(with an emphasis on the continued devel-opment of molecular diagnostic assays), and

the number of laboratories locally andabroad. As in the past, it will be important tocollaborate and support clinical programs inorder to provide the best in diagnostic servic-es that our clinicians and patients havecome to expect from our institution. Thisincrease in the scope and volume of activi-ties will require more space for faculty andstaff. The Hospital has committed substan-tial space in the planned Critical Care To w e rthat will allow the consolidation and expan-sion of pathology services currently inCarnegie, Meyer basement, and Pathology.In the meantime, expansion of pathologyservices will continue at our Hopkins proj-ects located in Kuala Lumpur, Uganda,China, and no doubt several new interna-tional sites.

Education priorities will include theexpansion of our web based educationalprograms, CME courses, pathobiology grad-uate student program, and our residency

and fellowship programs. I am pleased toreport that the Hospital has agreed to fundtwo more resident positions starting nexty e a r. A major initiative will be the submis-sion of new training grant proposals forgraduate students, fellows, and allied healthstudents.

With the substantial increase in NIHand other sources of funding, it will beessential that we take advantage of the fund-ing opportunities to strengthen our existingresearch programs and invest in new areasthat complement and support institutionalinitiatives such as the breast cancer programto name just one. Dean Miller shares thisview and has agreed to initially fund newfaculty positions and allocate up to 20,000sq ft of additional research space toPathology over a 5 year period. Two thirds ofthis new space will be available to Pathologyin 2003. In the meantime, space will contin-

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Director’s Corner

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Director’s Corner

A re you looking for intensive education intwo areas that pathologists encounter on a

daily basis? Are you in a busy group that makesslipping away for mid-week CME venues diffi-cult? Johns Hopkins might have the right con-tinuing education opportunity for you!

From November 2-5, 2001, the Divisionsof Gynecologic Pathology and GastrointestinalPathology teamed together to offer four days ofCME from Friday morning through Mondayafternoon at the Renaissance Harborplace Hotelin Downtown Baltimore. Drs. Robert Kurmanand Brigitte Ronnett directed the Gynecologiccomponent of the course and Drs. ElizabethMontgomery and Susan Abraham the gastroin-testinal segment. The first two days built on anexisting popular course devoted to gynecologicpathology and covered a wide range of topicsconcerning diseases of the ovary, cervix, vulva,uterus, and gestational trophoblastic disease.Hopkins faculty included Drs. Kurman,Ronnett, Pizer, and Perlman. Guest speakersincluded Drs. Jeffrey Seidman from Wa s h i n g t o n

Hospital Center and Robert H Young fromMassachusetts General Hospital. The two finaldays were a new Johns Hopkins offering devotedto gastrointestinal pathology coveringesophageal, gastric, pancreaticobiliary, liver,and colonic diseases. Dr. Borowitz from the divi-sion of Hematopathology discussed gastroin-testinal lymphomas and Dr. Thomas Hendrixfrom the Gastroenterology Service was also fea-tured. Drs. Abraham, Argani, Bhagavan,Eshleman, Hruban, Iacobuzio-Donahue,Maitra, Montgomery, Torbenson, Wilentz, andYardley from the Division of GastointestinalPathology contributed to the program. An excit-ing set of outside speakers included Drs. JoelGreenson from the University of Michigan,Zachary Goodman from the Armed ForcesInstitute of Pathology, and Cyril Fisher from theRoyal Marsden Hospital in London.

Mark your calendars for next year -combined Gynecology and GastrointestinalPathology CME Course will be held November8-11, 2002. n

Combined Johns Hopkins Continuing Medical EducationCourse in Gynecology and Gastrointestinal Pathology

ue to be tight so faculty will need to plannew initiatives carefully when it comes tospace requirements for additional equip-ment, staff, storage, and bench space.

The success of these ambitious initia-tives will mostly depend on our faculty andstaff. Making the discovery and dissemina-tion of new knowledge a priority of our aca-demic efforts has been what has kept JohnsHopkins at the medical forefront. Applyingthis newly found knowledge to diagnosticand treatment advances in patient care isone of the major reasons we continue to beranked the number one hospital in theUnited States. It is essential that each of ourfaculty be engaged in each of these activitiesto maximize the productivity of these efforts.Hospital and University staff will be equallyimportant in the implementation and con-tinued success in our ability to conductresearch and provide outstanding pathologyservices for patient care. n

phlebotomy staff. Later this year the entire staffwill participate in Customer Service Tr a i n i n g .The outcome of the efforts will be monitored onthe Hospital’s ongoing Patient SatisfactionS u r v e y.

With 80% of the hospital’s 5,000 dailytransactions originating or ending in one of theCore Laboratory areas, the daily performance ofthe pneumatic tube system has a dramaticimpact on Core Laboratory workflow and turn-around times. The Processing Area monitorspneumatic tube performance on an hourlybasis. The short term feedback has been used tomake minor adjustments in the system.A d d i t i o n a l l y, long-term volume projections havebeen submitted to restructure and fix majorb o t t l e n e c k s .

C u r r e n t l y, Specimen Processing handlesup to 500 samples per hour manually. Afterreviewing several options, management selectedthe Tecan FE 500 (see article page 6). Later thisFall the Tecan will arrive introducing automa-tion to specimen processing. The outcome ofthis project is to normalize the turnaround

The New “Non” Core Laboratory

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times of sample handling and improve theaccuracy of specimen aliquoting.

Customer Service will continue to expandits role internally. Customer Service is assist-ing Specimen Processing with communication,sample add-on’s, and urgent call backs. TheTecan will also have a positive impact inCustomer Service by lending automation to thecurrent manual specimen processing system.

One of the earliest areas to be evaluatedwas JHOC’s Express Testing Laboratory. Buildingon the successes in the Department’s OutreachProgram, chemistry testing was transferred fromExpress Testing to the Core Laboratory in April.After four months of smooth operations,Hematology and Urinalysis were transferred tothe Weinberg and Core Laboratory respectively.This operational change has had limited impactto the Department’s customers, but a net savingsof 5.0 FTE’s (through attrition). Express Te s t i n gPhlebotomy remains in place under JHOCAdministration serving up to 400 patients eachd a y.

Main Chemistry has had one of the largestworkload increases (+25%) this year withoutany increase in staff. Under the close watch ofJane Tolentino, turnaround times and result

integrity have been maintained. Other systemchanges such as consolidating ammonia’s onthe multichannel analyzers and evaluating syn-ergies between osmolalities and urinalysis are planned for this fall.

In Hematology, the major focus was toopen up the area and allow for better sampleflow in Coagulation and Urinalysis. With thetransfer of over a 100 urines per day from JHOC,work in urinalysis is currently overwhelming.Relief is on the way with the Bayer Atlas urinal-ysis analyzer planned to be implemented bymid November. After considerable review Dr.Kickler and Dana Anderson hope to develop analgorithm to reduce the number of urinemicroscopics performed by 50%.

Special Chemistry will also be implement-ing changes in the near term. On November1st, acid phosphatase was consolidated on theTOSOH. The staff is also considering expand-ing immunoassay testing to 12 hours each day.This would normally provide next day resultsincluding Thyroid Function tests to physiciansordering multidisciplinary tests. Longer term,D r. Chan and Dr. Sokoll are evaluating thedirection of immunoassay testing. Every oppor-

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Onikepe Adegbola, M.B.B.S.

Onikepe is originally from Nigeria. Shereceived her M.B.B.S. from the College of

Medicine, University of Lagos, in Nigeria in1995. After completion of her medical degree,Onikepe did a one-yearrotating internship inMedicine, Pediatrics,S u r g e r y, Obstetrics andGynecology at the EKOHospital in Lagos,Nigeria. The followingyear she became aVisiting Physician inthe Department of Hematology at AlbertEinstein College of Medicine in New York. In1998, she began a residency in Pathology atColumbia University College of Physicians andSurgeons in New York in order to develop asolid foundation for the study of disease.Onikepe just recently completed a year in thelaboratory of Nina Agabian at UCSF, where sheworked on Candida genetics, specifically a novelgene family postulated to have a role inCandida pathogenesis. As a student in thePathobiology Program, Onikepe hopes to pur-sue her ultimate goal of becoming an inde-pendent investigator with her own laboratoryworking on the pathogenesis of disease.

Stina M. Fangmark

Stina is originally from Sweden. She receivedher B.A. degree in Biology/Philosophy from

the College of NotreDame of MD in May of2001 where she gradu-ated Summa CumLaude. It was duringher senior year of theI n t e r n a t i o n a lBaccalaureate that shechose to research the hereditary disease FA P(Familial Amyloidotic Polyneuropathy Ty p e 1 )as her extended essay. Her passion for researchgrew as she became more aware of the toolsavailable to help individuals suffering from thisdisease through research. After completion ofher essay, she was asked by a Swedish supportorganization of families of FAP patients to haveher review article “Suggested Causes of FamilialAmyloidotic Polyneuropathy Type 1, and LiverTransplantation as a Plausible Method of

Therapy” appear on their web page. Stinahopes to be able to continue research in thefield of disease mechanisms, especially focusingon diseases of late and unknown onset.

Craig N. Morrell, D.V. M .

Craig is originally from Ontario, Canada.He received his undergraduate degree in

Biology from Brown University in 1995.T h e r e a f t e r, he earned a D.V.M. from Tu f t sU n i v e r s i t y, School of Veterinary Medicine in2000. While anundergraduate stu-dent at Brown, Craigco-authored two pub-lications in highlyregarded scientificjournals includingN a t u r e. This produc-tive research led himto pursue postdoctoraltraining inComparative Pathology at Johns Hopkins, tofurther his understanding of the pathophysiolo-gy of disease. Craig has chosen to continue hisstudies in the Pathobiology Program to achievehis goal of gaining a great appreciation of themorphologic aspects of various human andanimal diseases.

Colleen R. Mulvey

Colleen was born in Atlanta, Florida. Shereceived her B.S. in Biochemistry from

Florida State University in April of 2001.Colleen was a part-time Research LaboratoryTechnician at theNational HighMagnetic FieldLaboratory inTallahassee fromAugust of 1999through April of 2001.While at the NationalHigh Magnetic Lab,she was selected to doresearch under anREU-NSF training grant. The focus of theresearch was the physiological process of mus-cle contraction. During this time, she alsowrote an honors thesis on the “OrientationalChanges of ELC in Skeletal Muscle Fibers”.Colleen has chosen the Pathobiology Program

to continue to develop her research skills in thestudy of infectious disease in humans.

Eric B. Kuchner, M. H. S.

Eric is originally from Montreal, Canada. Hereceived a B.A. degree in Political Science,

with a minor in Trumpet Performance Studies,from Johns Hopkins University in May of 1998.In May of 2001, hereceived a M.H.S. fromthe School of Hygieneand Public Health ofJohns HopkinsU n i v e r s i t y. While com-pleting his MastersDegree, Eric worked inthe lab of John Laterra,M.D., Ph.D. at the Kennedy Krieger Institute inthe Department of Neurology. There he playeda key role in designing and cloning novelchimeric U1/ribozymes to inhibit PTEN geneexpression in human glioblastoma cell lines.Eric is pursuing a Ph.D. in Pathobiology so thathe will be equipped to help fight neurologicald i s e a s e s .

Bruce K. Huang

Bruce was born in Washington, D.C. Hereceived his B.A. in May of 1999 from The

Johns Hopkins University where he graduatedwith general and departmental honors. Bruceis currently working in the lab of GaryPasternack where hedeveloped a phage-based genetic library ofPC3 prostate cancercell line for use in yeasttwo-hybrid systemassay to elucidate pro-teins interacting withpp32 tumor suppressorprotein. He is also aiding in the investigation oft u m o r-reducing potential of pp32 whenexpressed in tumors derived from prostate andbreast cancer cell lines using athymic murinemodel. Bruce is committed to a career in bio-medical research. He has developed a keeninterest in the applications of molecular biologyand genetic engineering towards the treatmentof human diseases and he feels that the study ofPathobiology will better equip him for a careerin this field.

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Department of Pathology New Pathobiology Graduate Students, 2001-2002

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The Core Laboratory will soon introduce lab-oratory automation into the specimen pro-

cessing area. Automated instrumentation hasbeen in the Core Laboratory Chemistry andHematology sections for years. The installationof a Tecan Genesis FE500 is the first step towardintroducing automation into the specimen pro-cessing area. If everything proceeds as planned,the instrument should be operational before theclose of the calendar year.

The instrument has an expanded through-put of 500 tubes per hour. Individual barcodedvacutainer tubes are loaded into specimen racksand placed on the instrument entry tray. Theinstrument handles one specimen at a time andperforms the function of sorting, centrifugation,decapping, secondary barcode label printing,aliquot labeling, aliquot pipeting, and rackinginto actual instrument carriers for the Hitachi,Sysmex, BCS, and the TOSOH instruments. Theinstrument will be bi-directionally interfaced tothe Pathology Data System. Each specimen willbe individually queried to determine potentialprocessing, aliquoting, and racking status.

The instrument will work in parallel withPDS event queue software. Each specimen will

be updated with the date and time that the spec-imen was read at the Tecan entry point andagain when the specimen is racked into the dis-charge platform. The instrument itself runs ona windows based PC application and uses intu-itive software and built in intelligence to providetotal system management. Each step of a speci-m e n ’s automation process is graphically dis-played on screen, providing the operator withreal-time feedback on every function. Theinstrument requires minimal maintenance andvirtually eliminates the risk of manual samplealiquoting errors. This is hopefully the first step toward futureplans to introduce Total Laboratory Automation(TLA) into the Core Laboratory. This first phaseinstrument will establish the groundwork forfuture systems with expanded capabilities anddirect links to the laboratory analytical systems.The introduction of this system will create awave of change in the way we handle andprocess all of our patient specimens both oncampus and at our outreach facilities. The nextfew months should be both an exciting andchallenging period in the pre-analytical area ofthe Core Laboratory. n

The Tecan is Coming! The Tecan is Coming!

Medical students peer into their microscopesto see a pair of owl eyes staring back at

them and excitedly realize they have identifiedthe Reed-Sternberg cell nucleus characterizingH o d g k i n ’s disease. Dorothy Reed Mendenhalldiscovered this cell in 1902 and provided someof the earliest and most detailed descriptions ofH o d g k i n ’s disease. Though she encounteredmany challenges as a woman in medicine, shesuccessfully combined marriage and a familylife with a career, a feat that continues to chal-lenge female physicians a century later. Unableto find suitable positions in Pathology becauseof her gender, Reed spent the majority of hercareer in pediatrics and made significant con-tributions to the field of maternal and childhealth. (1)

Born in 1874, into a mid-western manu-facturing family of Columbus, Ohio, DorothyReed was the youngest of two daughters. She

was educated at home until the age of 13 andeventually matriculated to Smith College in1891. During a second year biology classtaught by Professor Harris Wilder she realizedher potential as a physician. At the conclusionof one of his lectures, she recalls thinking,“This is it, this makes sense-this is what I havebeen waiting for all these years.” Her family’sresponse to her subsequent decision to attendmedical school was less than enthusiastic. Hermother was “upset” and other family memberswere “aghast.” One relative even wrote toD o r o t h y ’s mother and stated that Dorothy wasno longer welcome in New York and impliedthat her career choice would interfere withsocial relationships. Nonetheless, Dorothyentered Johns Hopkins in 1896 and her relativesreferred to her during this time as being “Southfor the winter.”

From her first days at Johns Hopkins, Reed

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DOROTHY REED MENDENHALL (1874-1964) JHU SOM CLASS OF 1900

Dorothy Reed Mendenhall (1874-1964)

Congratulations to 3rd Annual Pathology

Young Investigators’ DayAwardees

For Excellence in Basic ResearchMarina G. Afanasyeva, M.D.Wen-Fang Cheng, M.D.Chih-Ling ChouDavid ElliottZiya Kaya, M.D.Laura K. Richman, D.V. M .Anne K. Vehmas, M.D.

For Excellence in Clinical ResearchElizabeth A. Allen, M.D.Theresa T-Y Chan, M.D.Magdalena B. Czader, M.D., Ph.D.Denis M. McCarthy, M.D.Dwight H. Oliver, M.D.Anil V. Parwani, M.D.Monica Srodon, M.D.David M. Steinberg, M.D.Warren S. Tanz, M.D.Michael S. Torbenson, M.D.Keith E. Vo l m a r, M.D.

FUNDING OUR FUTURE

W ith your wonderful and generoussupport, we have made significant

progress in our campaigns to honor Drs.Ya r d l e y, Eggleston, Erozan, andHeptinstall through the creation ofnamed funds and fellowships that sup-port the careers of young pathologists.Please consider supporting one or moreFellowships again this year.

The Joseph C. Eggleston Fund in Surgical Pathology

The Joseph C. Eggleston Fund in SurgicalPathology honors Joseph C. Eggleston, M.D.,

’62, formerDirector ofS u r g i c a lPathology andProfessor ofP a t h o l o g y. Dr.Eggleston touchedmany of our liveswith his dedicationto excellence inS u r g i c a l

Pathology and his outstanding teaching. Theincome from this endowed fund will be allocat-ed each year to a surgical pathology resident orjunior faculty member in the Division ofSurgical Pathology for projects that supporttheir career development in surgical pathology.We are pleased to announce that Dr. ChristineIacobuzio-Donahue is the first recipient of anaward from the Joseph C. Eggleston Fund. Dr.Iacobuzio-Donahue received the award for herwork developing new markers of pancreaticc a n c e r.

The Yener S. Erozan Fellowship inC y t o p a t h o l o g y

The Yener S. Erozan Fellowship inCytopathology pathology honors Yener S.Erozan, M.D., Director of Emeritus of theCytopathology Institute and past President ofthe American Society of Cytopathology. Dr.Erozan is a much loved teacher and diag-nostician who continues to have a wonder-ful influence on the Division ofCytopathology and on the Department.Income generated from this endowment willbe allocated to a fellow in Cytopathology tosupport the development of their career.

The Robert H. Heptinstall FellowshipThe Robert H. Heptinstall Fellowship hon-

ors Robert H. Heptinstall, M.D., former BaxleyProfessor and Director of Pathology. Dr.Heptinstall is well known to all of us for his textbook, his scientific accomplishments and forhis wonderful personality - his impatience withpretension, his wit and humor, and his vividstorytelling. The Robert H. HeptinstallFellowship will promote research activities andclinical training of outstanding young patholo-gists pursuing careers in research.

The John H. Yardley Fellowship inGastrointestinal Pathology

Thanks to your generous support, we arepleased to announce that The John H. Ya r d l e yFellowship in Gastrointestinal Pathology is nowfully endowed! As of October 16, 2001, over$850,000 has been raised or pledged. ThisFellowship will promote the research activitiesand/or clinical training of promising patholo-

gists pursuing advanced training in the study ofgastrointestinal disease in the Department.

The recipient of the John H. Ya r d l e yFellowship for the Academic Year 2001-2002 isD r. Anirban Maitra. Dr. Maitra received his resi-dency training at the University of Te x a sSouthwestern. Dr. Maitra’s research, under thementorship of Drs. Aravinda Chakravarti andRalph Hruban, will focus on the application ofsingle nucleotide polymorphism technology(HuSNP chip) to the study of familial pancreat-ic cancer. The John H. Yardley Fellowship is awonderful example of how private giving canboth honor our treasured faculty and, at thesame time, support the careers of young pathol-o g i s t s .

We ask that you make supporting thesefunds and fellowships an annual event. What awonderful way to honor these great physicians.We are enclosing a self-addressed return enve-lope to facilitate your contribution this year.Please contact Dr. Ralph Hruban at 410-955-2163 or rhruban@jhmi.edu for additionalinformation. If you would like to use a separateenvelope, you may send your tax-deductiblecontribution payable to The Johns HopkinsUniversity to:

Attn: Mabel P. Smith, Department of Pathology,Johns Hopkins Hospital,

Carnegie 428, 600 North Wolfe Street,

Baltimore, MD 21287-6417

Thanks to all of you that have made this support a reality for our young pathologists. n

Joseph C. Eggleston

Dr. Maitra and Dr. Yardley

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Ty Abel

T y received his Bachelors degree inPsychology from Boise State University. He

then attended the University of Arizona, wherehe earned his Masters and MD/PhD. He hasconsiderable hospitalwork experience,including positions inphlebotomy andm i c r o b i o l o g y. Hisresearch focused on theeffects of aging andgonadal steroid with-drawal on the humanhypothalamus. He isoriginally from Boise, Idaho and enjoys skiing,fishing, and biking. He will be joining us onthe accelerated AP/NP track.

Maryam Armin Farinola

Maryam was born in the New York City area.She briefly attended Michigan State

U n i v e r s i t y, before completing her B.S. in Biologyat Wayne State University in Michigan. Shecontinued at Wayne State for her M.D. degreeand volunteered hertime to Habitat forHumanity and healtheducation for middleschool students.M a r y a m ’s researchactivities have includedwork with MUC1 andMUC2 in the differenti-ation of oncocytoma and chromophobe renalcell carcinoma. In her spare time she enjoysscuba diving and foreign travel; she is fluent inFarsi. Maryam will pursue AP/CP training.

Jennifer Broussard

Jennifer is from Manhattan, Kansas. Sheearned her

Bachelors degree inBiology from theUniversity of Missouri-Columbia, and herM.D. degree from theUniversity ofMichigan. While inmedical school, shespent time working in

a medical clinic for the homeless. Jennifer alsoparticipated in the Howard Hughes MentorshipProgram, during which she studied the effectsof retinoic acid on the differentiation of intestin-al goblet cells. She enjoys rock climbing, gui-t a r, and ballet, and she has been both a balletand ballroom dance instructor. Jennifer will beon the AP/CP track.

Dengfeng Cao

Dengfeng is origi-nally from

Hunan, China. He didhis under- g r a d u a t ework in Premedicineat Beijing Universityand earned his M.D.from Peking UnionMedical College. During Medical school, hewas involved in hypertension screening andblood donation campaigns. After moving to theUnited States in 1996, he earned a Ph.D. at theUniversity at Pittsburgh. His work focused oninvestigating recognition specificity betweenproteins and DNA. His hobbies include travel,swimming, and fine cuisine. Dengfeng willalso be training in AP/CP.

Marc Halushka

Marc is originallyfrom Atlanta. He

earned a B.S. inBiochemistry fromIndiana University,before moving toCleveland for hisMD/PhD at Case We s t e r nReserve University. His research involved a proj-ect that characterized single nucleotide poly-morphisms in hypertension candidate genesusing microarray technology. Marc will betraining in AP only.

Gregory Hosler

Greg was born in Washington, D.C. He com-pleted his B.S.E. at Princeton and his

MD/PhD at Southwestern in Texas. Hisresearch activities have included studying mini-mal residual disease evaluation as a prognosticindicator in T-Cell Acute Ly m p h o b l a s t i cLeukemia. He was an instructor for the Dallas

County HealthDepartment and edu-cated rural health careworkers about labora-tory diagnosis of sexu-ally transmitted dis-eases. His interestsinclude baseball, golf,and basketball, and he is fluent in Spanish.Greg is interested in AP/CP training.

Claudio Mosse

Claudio is originallyfrom Santiago, Chile.

At Cornell, he double-majored in Chemistryand Biology. He thenearned an MD/PhD atthe University at Vi r g i n i aand studied mechanismsof MHC Class I antigen generation inmelanoma. His extra-curricular experiencesincluded Judo instruction and HIV education formiddle school students. Claudio is trilingual,with proficiency in Spanish, English, andGerman. His hobbies include Judo, mountainbiking, hiking, cooking, and fishing. Claudio isinterested in AP/CP training.

Min Wa n g

Min is originally fromAnhui, China where

he earned his M.D. fromBengbu Medical College.He continued his educationat Tianjin MedicalUniversity where he earnedhis M.S. while completing aresidency in Ophthalmology, followed by hisPh.D. from Peking Union Medical College inBeijing, China. Min has completed anOphthalmic Pathology Fellowship at theUniversity of Illinois before continuing on as aResearch Scientist at Celtrix Pharmaceuticals,as well as spending time as a Senior ResearchAssociate at the University of Kentucky. Hisresearch activities include cDNA micro-arraystudies of Alzheimer’s Disease, and neuronalcell damage and degeneration in the retina.Min will be joining us as a first year NP fellowfrom the University of Kentucky where he hascompleted a residency in Anatomic Pathology.

Department of Pathology Incoming House Staff, 2001-2002

Page 8

Primary Faculty Changes - 2001

New FacultyZhen Zhang Associate Professor C h e m i s t r yJohn Ti c e h u r s t Assistant Professor Clinical Labs, BayviewCharles Eberhart I n s t r u c t o r N e u r o p a t h o l o g yDavid Berman I n s t r u c t o r Molecular PathologyTheresa Chan I n s t r u c t o r Urologic PathologyAnirban Maitra I n s t r u c t o r G.I./Liver PathologyKathleen Murphy I n s t r u c t o r Molecular Diagnostic Path.Nicole Parrish I n s t r u c t o r M i c r o b i o l o g yRobb Wilentz I n s t r u c t o r G.I./Liver Pathology

D e p a r t u r e sJoel H. Saltz Director and Chair Dept. of Biomedical Infomatics

Associate V. P. and CIO Ohio State University Health SciencesRaymond E. Lund Associate Professor R e t i r e dMark Sherman Associate Professor NCI, NIHLaura Mamounas Assistant Professor N I HT. T. Wu Assistant Professor M. D. Anderson Cancer CenterTahsin Kurc I n s t r u c t o r Ohio State UniversityUmit Catalyurek Research Associate Ohio State University

P r o m o t i o n sBrooks Jackson Baxley Professor & Director Department of PathologyLorraine C. Racusen P r o f e s s o r Kidney/Urologic PathologyJonathan Schneck P r o f e s s o r I m m u n o l o g yIe Ming Shih Assistant Professor Gyn PathologyGloria Su Assistant Professor G.I./Liver PathologyEdward We i r Assistant Professor H e m a t o p a t h o l o g yJining Bai I n s t r u c t o r Molecular PathologyAbdel Hamad I n s t r u c t o r I m m u n o l o g yChien-Fu Hung I n s t r u c t o r Gyn Pathology

On November 2, 2001, Dr. Jonathan Epsteinwas named the first Rose-Lee and Keith

R e i n h a r dProfessor inU r o l o g i cP a t h o l o g y. Dr.Epstein recentlyhad the opportu-nity to meet KeithReinhard alongwith Dr. PatrickWalsh in NewYork. Mr.Reinhard is chair-man of the largest advertising agency networkin the United States and the third largest agencynetwork in the world with 206 offices in 99countries. In the United States, his advertisingcompany manages the McDonalds andBudweiser accounts. He is responsible for theMcDonalds slogan, “You deserve a break today. ”K e i t h ’s background is on the creative side of theadvertising business and his company has won252 Cannes Lions awards for advertising, whichis 68 more than its nearest competitor.

Keith Reinhard was treated by Dr. Wa l s hfor prostate cancer and is actively involved inraising funds for the study of prostate cancer.In addition to providing funds for the UrologicPathology Professorship, Keith and Rose LeeReinhard provided an additional $1 Million giftto be placed in a fund for urological pathologyresearch. This fund will generate approximate-ly $40 to $50 thousand dollars per year, provid-ing a continual source of funds to further thestudy of prostate cancer pathology.

This award recognizes the importance ofclinically related research. The Department ofPathology is very grateful to Dr. Walsh. For aclinical department head to raise money for aProfessorship for someone whose primaryappointment is in another department is trulyremarkable. Dr. Walsh also has the vision torecognize the importance of Pathology in themanagement of patients with prostate cancer.This Professorship in Urologic Pathology is thefirst of its kind in the world. n

Dr. Jonathan Epstein

New Professorship inUrologic Pathology

tunity to consolidate and systemize this testingwill be considered.

The Weinberg Clinical Laboratories con-tinue to be challenged as the acuity levels ofpatients in the operating rooms and the inten-sive care units continue to rise. Two hundredfifty additional Hematology profiles each dayfrom JHOC have also added to the complexity ofthe laboratory. Special Coagulation is project-ing four new assays by the end of the calendary e a r. Molecular Hematology will be switchingto a more automated and specific HbA1C assayin December. Flow Cytometry volumes and testmenu continue to expand each year.

The New “Non” Core LaboratoryContinued from page 3

The Emergency Room Laboratory nowutilizes the same technologies for chemistry andhematology as the Main Laboratory. This tran-sition reduced multiple inventories and easedcross training. Dr. Palmer- Toy and GregGerhardt are working on a PerformanceImprovement initiative with ER Nursing toreduce hemolysis rates to industry standardrates of less than 5%.

The Critical Care Laboratory has seenimprovements in the communication of data tohospital result reporting systems. This summer,Mike Enlgestad working with nurse managersfrom each of the Intensive Care Units was ableto convert from the dependency of phone/paperreporting to electronic communication. Inaddition to ensuring the accurate communica-

Continued on page 9

The New “Non” Core LaboratoryContinued from page 8

Page 9

New Grants and Contracts Awarded to Pathology FacultyFA C U LTY MEMBER AWARD TYPE A G E N C Y D AT E S T O TAL FUNDINGBai, Jining Inst. Grant J H U / I R G 0 5 / 0 1 / 0 1 - 0 4 / 3 0 / 0 2 20,000 Bai, Jining G r a n t Dept. of Defense 0 5 / 1 5 / 0 1 - 0 6 / 1 4 / 0 4 490,499 Bai, Jining G r a n t Dept. of Defense 0 5 / 1 5 / 0 1 - 0 6 / 1 4 / 0 2 81,750 Barasoni, Laura G r a n t National Kidney Foundation 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 2 14,273 Berman, David K08 Grant N I H / N I D D K 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 6 630,450 Borowitz, Michael R01 Grant N I H / N C I 0 4 / 0 1 / 0 0 - 0 3 / 3 1 / 0 5 1,640,377 Bova, Steve R01 Grant N I H / N C I 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 6 1,201,725 Caturegli, Patrizio G r a n t American Thyroid Assoc. 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 2 25,000 Chan, Daniel C o n t r a c t Roche, Diagnostics 0 1 / 0 2 / 0 1 - 0 1 / 0 1 / 0 2 90,000 Demarzo, Angelo R01 Grant N I H / N C I 0 6 / 0 1 / 0 1 - 0 4 / 3 0 / 0 4 869,744 Demarzo, Angelo G r a n t C a p C u r e 0 6 / 0 1 / 0 1 - 0 5 / 3 1 / 0 2 68,880 Eberhart, Charles G r a n t Burroughs Wellcome Fund 0 9 / 0 1 / 0 1 - 0 8 / 3 1 / 0 6 508,000 Gabrielson, Edward G r a n t Dept. of Defense 0 7 / 1 5 / 0 1 - 0 7 / 1 4 / 0 4 490,499 Goggins, Michael G r a n t Lustgarten Foundation 0 1 / 0 1 / 0 1 - 1 2 / 3 1 / 0 2 250,000 Goggins, Michael R03 Grant N I H / N C I 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 3 163,500 Goggins, Michael R03 Grant N I H / N C I 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 3 163,500 G u a y, Laura S u b c o n t r a c t Family Health International 0 2 / 1 6 / 0 1 - 0 8 / 3 1 / 0 1 8 2 , 6 1 5G u a y, Laura G r a n t Glaser Pediatric AIDS Fdtn. 0 3 / 0 1 / 0 1 - 0 2 / 2 8 / 0 3 286,974 Hatanpaa, Kimmo G r a n t American Fdtn. for Aging Research 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 2 25,000 Jackson, Brooks S u b c o n t r a c t Family Health International 0 2 / 1 6 / 0 1 - 0 8 / 3 1 / 0 1 4 4 8 , 7 9 7Jackson, Brooks G r a n t Doris Duke Foundation 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 2 3 2 5 , 0 0 0J a n k o w s k y, Joanna G r a n t French Alzheimers Fdtn. 0 9 / 0 1 / 0 1 - 0 8 / 3 1 / 0 2 35,000 J a n k o w s k y, Joanna G r a n t American Health Asst. Fdtn. 0 4 / 0 1 / 0 1 - 0 3 / 3 1 / 0 3 100,000 Merz, William C o n t r a c t Merck & Co. 0 6 / 0 1 / 0 1 - 0 5 / 3 1 / 0 2 52,635 M o n t g o m e r y, Elizabeth G r a n t Crohns & Colitis Foundation 0 6 / 0 1 / 0 1 - 0 4 / 3 0 / 0 2 15,955 Perlman, Elizabeth U01 Grant N I H / N C I 0 4 / 0 1 / 0 1 - 0 3 / 3 1 / 0 6 1,924,231 Racusen, Lorraine R13 Grant N I H / N I A I D 0 4 / 2 1 / 0 1 - 0 4 / 2 0 / 0 2 2,000 Racusen, Lorraine G r a n t National Kidney Foundation 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 2 2,410 Roden, Richard G r a n t Stewart Tr u s t 0 5 / 0 1 / 0 1 - 0 4 / 3 0 / 0 2 32,100 Roden, Richard R21 Grant N I H / N C I 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 3 327,000 Shih, Ie-Ming G r a n t Stewart Tr u s t 0 5 / 0 1 / 0 1 - 0 4 / 3 0 / 0 2 32,100 Sokoll, Lori C o n t r a c t Dade Behring 0 4 / 1 6 / 0 1 - 0 8 / 3 1 / 0 1 30,400 Sokoll, Lori C o n t r a c t Eichrom Te c h n o l o g i e s 0 4 / 1 5 / 0 1 - 1 2 / 3 1 / 0 1 30,000 Su, Gloria Inst. Grant JHU/Bernstein Aw a r d 0 4 / 0 1 / 0 1 - 0 3 / 3 1 / 0 2 15,000 Su, Gloria G r a n t Lustgarten Foundation 0 1 / 0 1 / 0 1 - 1 2 / 3 1 / 0 2 250,000 Su, Gloria R03 Grant N I H / N C I 0 7 / 0 1 / 0 1 - 0 6 / 3 0 / 0 3 163,500 Troncoso, Juan C o n t r a c t Neurologic, Inc. 1 1 / 0 1 / 0 0 - 1 0 / 3 1 / 0 3 185,000 Troncoso, Juan G r a n t Alzheimer's Association 0 9 / 0 1 / 0 1 - 0 8 / 3 1 / 0 4 240,000 Tu d e r, Rubin R01 Grant N I H / N H L B I 0 4 / 0 1 / 0 1 - 0 8 / 3 1 / 0 1 263,307 Tu d e r, Rubin R01 Grant N I H / N H L B I 0 4 / 0 1 / 0 1 - 0 8 / 3 1 / 0 4 1,046,503 Wong, Phil G r a n t American Health Asst. Fdtn. 0 4 / 0 1 / 0 1 - 0 3 / 3 1 / 0 3 200,000 To t a l $12,823,724

tion of data, it has provided a more sysmaticapproach to blood gas and electrolyte testing.

In May, the GreenSpring laboratory trans-ferred its chemistry testing to the JHH C o r eL a b o r a t o r y. Green Spring will continue to per-form hematology and reproductive endocrine

tests onsite but in a new laboratory in PavillionII sometime this winter. A pneumatic tube willconnect the Oncology Suite with the laboratoryfacilitating 15 minute turnaround times onHematology profiles.

Staffing, particularly on off shifts andweekends, continues to be a challenge acrossthe Core Laboratory. Management is currentlyexperimenting with creative shifts such as 12

hour days, weekend only programs, and target-ed technical training programs to supplementexperienced staff.

The Core Laboratory team has been so cre-ative and enthused about changes that it has beena challenge to keep up with the evaluation andimplemtation of these ideas. The Core Laboratorylooks forward to the challenges presented by anever changing healthcare system. n

Page 10

experienced bias because of her gender.Dorothy Reed and a second female medical stu-dent, Florence Sabin, graduated fourth and sec-ond in the class, respectively. These rankingswould normally guarantee both students aplace on the house staff. However, Dr. We l c hexplained to Reed that two women medicalinterns was a “serious embarrassment” andsuggested that she consider other specialtiessuch as surgery or gynecology. Reed declined,and both graduates were given appointments inmedicine. She faced yet another controversy,h o w e v e r, when the faculty questioned whether awhite woman could serve on the black maleward. Dr. Reed spoke personally to Dr. Hurd,Superintendent of the Hospital, and insisted thatshe had proved herself having served as a med-ical student on the “colored wards, male andfemale, surgical and medical.” She won overthe faculty, and both students completed theirmedical internships. Reed then accepted a fel-lowship in pathology with Dr. Welch and wrotewhat would become her classic paper ofH o d g k i n ’s disease, based on the autopsies ofeight cases. Publishing her findings in theJohns Hopkins Hospital Reports in 1902, shedescribed a large binucleated cell characteristicof the disease, made a distinction between thedisease and tuberculosis, and suggested that itwas a chronic inflammatory illness due to anunknown pathologic agent. (2) Hodgkin’s dis-ease was later recognized as a malignant lym-phoma, and only recently have investigatorsbeen able to isolate Reed-Sternberg cells andprove that they are clonal proliferations of Blymphocytes.

Following her fellowship, Dr. Reed pon-dered her prospects for a future in pathologystating, “Pathology was the work I had likedbest in medicine, and the one I felt a real inter-est in following.” Dr. Welch had offered heranother year as a fellow but the stipend wasinadequate, particularly since Reed was sup-porting herself and her mother. When she fur-ther inquired about hopes for faculty promo-tion, Dr. Welch explained that “No woman hadever held a teaching position in the school andthat he knew there would be great opposition toit”. Although he attempted to find Reed otherpathology positions, she became discouraged byher inability to find work, gave up pathology,and in June 1902 she accepted a position as a

resident in pediatrics at the New York Infirmaryfor Women and Children. Leaving Hopkins, shesaid “It was one of the saddest periods of mylife…, Baltimore…. had always had a specialsignificance for me. On that day I turned myback on all I wanted most and started to makea new life for myself”. She continued her train-ing as a resident at Babies Hospital in New Yo r kfrom 1903 to 1906.

At the age of 32, Reed married Charles E.Mendenhall, a physicist she had met inBaltimore. For the next nine years, she retiredfrom medicine, devoting her time to her homeand family. Her first child, Margaret, diedshortly after birth of a cerebral hemorrhage dueto poor obstetrical care, but Reed went on tohave three more children. Shortly after thebirth of her last child, Dorothy was offered aposition as a lecturer in the Department ofHome Economics at the University ofWisconsin, where her husband was Professor. Atthe University of Wisconsin, she performed epi-demiologic studies on maternal and childhealth and also developed correspondencecourses for new mothers.

In 1917 when war duty took her husbandto Washington, D.C., she began working for theUnited States Children’s Bureau to reduce infantand maternal mortality. Reed studied childbirthpractices in Denmark and determined that theuse of midwives and a decreased rate of surgicalintervention were responsible for the country’slow infant morality. She published a paperadvocating greater use of midwives in 1929 thatcaused the revision of many delivery practicesin the United States. She also extended herinterest in child health to the war orphans ofFrance, Belgium and England. Clearly, herinterest in the field was a reflection on her ownobstetrical experiences. She wrote, “I had con-siderable to do with putting the emphasis backon the way life began, on the care of the moth-e r, and its great influence on life and health ofthe child, and of starting the work to improveconditions surrounding childbirth in our coun-try”… “As I look back on these years and myinterests (in delivery practices) the tragic deathof my first child …was the dominant factor…All the writing and teaching on safe maternity Ihave thought of as a memorial to Margaret, myfirst child and only girl.”

Reed continued to work in the field ofmaternal and child health until the age of 60when her husband’s illness forced her to give upher professional activities. Several of her chil-

dren followed in her illustrious footsteps. Herfirst son became President of Smith College andher second son, graduated from HarvardMedical School in 1939 and studied a year ofpathology at Johns Hopkins. Reflecting on herprofessional career, particularly after marriage,she wrote:

“When I look back over the last 60 yearsof my life, it seems as if my end was shapedslowly but surely…In the years of my familyr e s p o n s i b i l i t y, research, obstetrical training andpediatrics, all of which enabled me to go backto work after my children were born and tomake a worthwhile contribution to the city, thestate, and the nation.”

Dorothy Reed Mendenhall died in 1964 atthe age of 89. Her contributions to medicinecontinue to be recognized decades after herHopkins graduation. In a 1976 supplement toThe Johns Hopkins Medical Journal e n t i t l e d“Adventures in Medical Research” Dr. A.McGehee Harvey, former Physician-in-Chief ofThe Johns Hopkins Hospital, wrote:

“At a time when women were shunned bythe medical profession, Dorothy ReedMendenhall had the strength of character andintellectual power to successfully complete hermedical training, to make a significant contri-bution to the body of knowledge about disease,and to materially aid other women by her con-tributions to child and maternal welfare.”

Risa B. Mann, M.D.

R e f e r e n c e s1. Conway, Jill Ker, Editor . Written By Herself.Autobiographies of American Women : AnAnthology p 171 - 199.Vintage Books A divisionof Random House, Inc. New York 19922. Mendenhall DR. Diary, Folder 25, Page 51.Typed manuscript. [1894-1900] Located at :Dorothy Reed Mendenhall Papers, SophiaSmith Collection, Smith College, Northampton,Massachusetts. In Three Women at JohnsHopkins: Private Perspectives on MedicalCoeducation in the 1890s Joseph B. Shrager,MD. Annals of Internal Medicien. Vol 115; No.7, 1 October 1991.3. Reed, Dorothy M. On the pathologicalchanges in Hodgkin’s disease, with especial ref-erence to its relation to tuberculosis. JohnsHopkins Hospital Reports 10:133-196, 1902.

Acknowledgement: Mr. Gerard Shorb, ResearchAssociate, The Alan Chesney Medical Archives,and Rebecca Ashkenazy, M.D. n

MENDENHALLContinued from page 5

Page 11

On the Web…

The last six months have brought exciting developments to theDepartment's Web presence. We

are: • beginning to incorporate

streaming video and audio into our sites

• continuing to build upon our online professional education materials, and

• successfully using the web to increase private donations to support our research

We invite you to visit the web sitesbelow and continue to visit themain department site ( http://pathology.jhu.edu )Department members interested in devel-

oping new departmental web sites are

invited to attend the Web Development Group open meetings held alternating Mondays

at 10:00 A.M. (Carnegie489A). Please contact Coreen Byam at 410-614-3589 if you are

interested in attending a meeting.

Streaming Video of Grand Rounds h t t p : / / p a t h o l o g y 2 . j h u . e d u / d e p a r t m e n t / g r a n d r o u n d s . c f mContributing Faculty: Bill Westra and Norman Barker

New Division / Laboratory Web SitesDivision of Gastrointestinal Pathologyh t t p : / / p a t h o l o g y. j h u . e d u / g i p a t hContributing Faculty: Robb Wilentz, M.D.

The Cervical Cancer Research Lab of Dr. T.-C. Wuh t t p : / / p a t h o l o g y 2 . j h u . e d u / t c l a b /Developed by T.-C. Wu, M.D. and undergraduate students Richard Dzeng and Alan Wu

Professional Education Web SitesPancreas Cancer: From Genes to Tr e a t m e n th t t p : / / p a t h o l o g y. j h u . e d u / l u s t g a r t e nStreaming video by Pathology Photography & DoIt Interactive

On June 13 and 14, 2001, the Pathology Department hosted the 3rdannual meeting of the Lustgarten Foundation for PancreaticCancer Research. Watch and listen to the presentations throughstreaming video. Presenters include Johns Hopkins' own; MartyAbeloff, M.D., Ross Abrams, M.D., John Cameron, M.D., RalphHruban, M.D., Elizabeth Jaffee, M.D., Scott Kern, M.D., Steve Leach,M.D., and Burt Vogelstein, M.D.

Clinico-Pathologic Conferenceh t t p : / / o a c . m e d . j h m i . e d u / c p c / l i n k s . h t m lCoordinated by : Dr. Pedram Argani, Assistant Professor of Pathology; Dr. Charles Ye o ,

Professor of Surgery; Dr. Charles M. We i n e r, Associate Professor of Pulmonary Medicine

Each month an expert clinician is presented with the clinical course,radiological findings, and relevant laboratory results for a particu-lar patient. The clinical expert then puts a case together in a waythat is educational to all members of the Hopkins medical commu-n i t y, from medical student to senior clinician. The clinical expertpresents his or her discussion in Hurd Hall on the last Tuesday ofevery month, from 12 to 1 pm. Two weeks before every case presentation, details of the case, includ-ing images and other material (when available), are posted on theCPC web site. After the CPC has occurred, we post the clinician's andthe pathologist's presentations on the Web, as an ongoing medicaleducation exercise.

Disease-Specific Web SitesAlzheimer's Disease Research Centerh t t p : / / w w w. a l z r e s e a r c h . o r gContributing Faculty : David Borchelt, Ph.D., Jason Brandt, Ph.D., Donald Price,

M.D, Juan Troncoso, M.D.

The Alzheimer'sDisease ResearchCenter (ADRC) is aresearch programsupported by amajor grant fromthe National Instituteon Aging. The ADRCweb site providesinformation on the lat-est research, clinical studies & trials, and treatment programs at JohnsHopkins. It also features a section on the biological basis of the diseasethat is tailored to a non-scientific audience, primarily caregivers ofAlzheimer's patients.

Autoimmune Disease Research Centerh t t p : / / a u t o i m m u n i t y. p a t h o l o g y. j h m i . e d uContributing Faculty : Patrizio Caturegli, M.D., Noel R. Rose, M.D., Ph.D.

The John Hopkins Autoimmune Disease Research Center, formed in1999, provides the opportunity for basic scientists, clinicians, epi-demiologists and geneticists to come together in advancing the battleagainst autoimmune diseases through research, education and bet-ter communication, resulting, eventually, in improved clinical care.

Web Team: (L-R) Standing:Jennifer Brumbaugh, Amanda Lietman

Seated: Coreen Byam

http://www.alzresearch.org

Department of PathologyJohns Hopkins Medical Institutions600 North Wolfe Street, Carnegie 417Baltimore, MD 21287-6417

(410) 955-9790

J. Brooks Jackson, M.D., M.B.A.Baxley Professor and Director

E d i t o r :Ralph Hruban, M.D.

Managing Editors: Mabel Smith and Jennifer Galford

Technical Advisor:Mitch Heinz

P h o t o g r a p h e r :Pathology Photography Staff

Department of Pathology Web Site:w w w. p a t h o l o g y. j h u . e d u

CalendarOctober 2-5, 2002 Diagnostic Surgical Pathology and Cytopathology

Course, Milan, Italy

November 8-9, 2002 5th Annual Gynecologic Pathology CME Course:

Approaches to Common Problems with Emphasis

on New Entities and Techniques, Baltimore, MD

N o v e m b e r10 -11, 200 2 2nd Annual Current Topics in Gastrointestinal

Pathology CME Course, Baltimore, MD

December 14, 2001 Department of Pathology Holiday Party –

Turner Concourse 2-4pm

February 25, 2002 Johns Hopkins Pathology Alumni Reception

5:30 pm-7:30 pm Michigan A Room

Sheraton Chicago Hotel

April 14-20, 2002 National Laboratory We e k

April 22, 2002 Pathology Young Investigators’ Day

May 9-11, 2002 Mastering the Challenges of Cytopathology

May 17, 2002 Pathology Awards Dinner

May 19, 2002 Employee Appreciation Event at the

Baltimore Zoo

You are invited to join us at the Johns Hopkins Pathology Alumni Reception

February 25, 2002 - 5:30 pm - 7:30 pm Sheraton Chicago Hotel, Michigan A Room

301 East North Water Street Chicago, IL 60611 (312) 464-1000

Diagnostic SurgicalPathology and

Cytopathology Course,

Milan, ItalyOctober 2-5, 2002

For more information, please contact jepstein@jhmi.edu

h t t p : / / p a t h o l o g y 2 . j h u . e d u / c o n f e r-e n c e s / m i l a n . h t m