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    DevelopmentsanD InnovatIons

    Fighti

    CanC

    int

    Developi

    Wor

    DevelopmentsanD innovation

    paCt

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    programmeof actIonfor cancer therap

    hotos credits:

    hau Doan for IAEA: pages 7, 28

    . Calma/IAEA: page 3

    . de Bode/WHO: page 20

    M. Kokic/WHO: pages 27, 29-31

    Omobono/IAEA: page 19

    Perrier-Bonnet/AMCC-INCTR: page 22. Ryan-Rappaport/IAEA: page 24, back

    . Sachetti/IAEA: cover, pages 2, 6, 8, 9, 13, 14, 23, back

    WHO: pages 4, 5, 10-12

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    DevelopmentsanD InnovatIons

    ForeWorD

    Cancer is more than a health concern; indeveloping countries it is a looming crisis.

    Cancer already kills more people globallythan tuberculosis, HIV, and malaria combined,and the number is growing quickly. Unlesswe take urgent action, by 2030 over thirteenmillion people will die from cancer every year.The majority of these deaths will occur in

    developing countries.

    Cancer is not a death sentence; there areproven ways to prevent and cure cancer. Onethird of all cancers can be prevented, and athird can be successfully cured.

    The IAEA has been working for over 40 yearsto bring radiotherapy, a highly effectivetreatment for cancer, to low and middleincome countries. The need for radiotherapy,

    which can shrink and eliminate cancertumours, is very high in developing countries,where many cancers are diagnosed too late foreffective treatment. Sadly, in the developingworld, only 20% of patients who needradiotherapy can access it today.

    This is why I decided to make the ghtagainst cancer in developing countries myrst priority when I became Director Generalin December 2009. But, developing radiation

    medicine capacity is not enough to tacklecancer; a comprehensive approach is needed.Through its Programme of Action for CancerTherapy (PACT), the IAEA is combining itsexpertise in radiation medicine with theexperience of the World Health Organizationand other international partners to delivercomprehensive cancer control to the places

    that need it most.

    I call on everyone to take action to ght thecancer crisis in developing countries. PACT isdemonstrating how we can achieve successthrough partnerships in the ght to savemillions of lives by closing the gap in cancercontrol between rich and poor countries. Let's

    work together to save lives.Yukiya Amano

    IAEA Director General

    foreworD

    IAEA Director General Calls for

    Support in the Fight Against Cancer

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    People living in developing countries deserveaccess to proven standards of cancer controland care.

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    DevelopmentsanD InnovatIons

    tableoF Contents

    The Call to Fight Cancer 6

    IAEA's Programme of Action for Cancer Therapy (PACT) 8

    Current Cancer Crisis 12

    Supporting Sustainable Solutions 14

    PACT's Global Presence 16

    Cancer Control: A Vital Investment 18

    How PACT Helps 20

    Innovations 22

    Programme Highlights 26

    Achievement Through Strategic Partnerships 29

    How You Can Help 30

    Did

    you

    know

    40% ofall cancer

    deaths can b

    prevented

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    programmeof actIonfor cancer therap

    the callto fIght cance

    72% of

    cancer cases

    occur in

    developingcountries

    the Callto Fight CanCer

    Cancer is a global problem. In2010, cancer will kill nearly eightmillion people worldwide, whileover 13 million new patients willbe diagnosed with this disease.According to the World HealthOrganization (WHO), more thantwo thirds of these new cases

    and cancer deaths will occur inthe developing world, where theincidence of cancer continues toincrease at alarming rates.

    For new cancer patients luckyenough to receive treatment,a long process of medical careawaits. For example, the average

    treatment of ovarian cancerrequires 368 hours of therapyin the rst year alone. For manypeople in developing countries,cancer treatment is unaffordableor, more commonly, unavailable.Currently, there are 30 nations thahave no radiotherapy machines,

    and most cancer cases in low andmiddle income countries will bediagnosed too late to cure thedisease.

    The failure to include cancer andother non-communicable diseasesin the Millennium DevelopmentGoals has resulted in global funds

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    DevelopmentsanD InnovatIons

    being directed away from cancer, leavingmen and women diagnosed with cancer indeveloping countries largely forgotten.

    Cancer and other non-communicable diseasescontinue to be grossly underfunded. Currently,non-communicable diseases are responsiblefor 60% of deaths globally, but only receive

    about 1% of health funding worldwide.But there are many reasons for hope.

    Effective treatment for cancer exists andcomprehensive cancer control programmeshave worked in high income countries.There, although cancer continues to affect

    the population, the rate of cancer illnessand death has steadied, and many peoplediagnosed with cancer can expect to surviveand live healthy and productive lives aftertreatment.

    New resources, in the form of medicalequipment, medicine or health workers,

    can have an immediate, positive effect.But achieving positive results requirescoordinated action, based on a strategic andsystematic approach. PACT is working to buildpartnerships and bring the resources of theglobal health community together to ghtcancer around the world.

    the callto fIght cancer

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    Iaea's programmeof actIonfor cancer therap

    In developingcountries,

    about 70% of allcancer cases arediagnosed too

    late.

    iaea's programmeoF aCtionFor

    CanCertherapy (paCt)

    The IAEA, a specialized Agencyof the United Nations, is one ofthe world's leading organizationsdedicated to the peaceful uses ofnuclear science and technology.

    A critically important applicationof nuclear science is radiationmedicine, which is often the onlyoption for the diagnosis andtreatment of cancer. Controlled

    doses of radiation can help shrink,and even eliminate, canceroustumours. Radiation medicine isalso used to help diagnose canceraccurately and reduce the pain

    and suffering associated with thedisease. Approximately 5060%of people with cancer needradiotherapy at some point duringtheir treatment.

    For the last 40 years, the IAEAhas provided radiotherapyequipment and training to cancercentres in over 115 developingMember States. Based on this

    experience on the ground, theIAEA has recognized that providingradiotherapy equipment andtraining is not sufcient to addressa country's cancer burden.

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    DevelopmentsanD InnovatIons

    Unless comprehensive national plans tocontrol cancer are put in place, rates of cancerwill not be reduced. However, countries needassistance to generate the resources andcapacity needed to implement comprehensivecancer control guidelines and provide servicesto their populations. In addition, the differentstakeholders ghting cancer need to shareinformation and fully align themselves withthe cancer control plans being developed.

    That is why the IAEA established PACT in2004. PACT is an umbrella programme forall of the IAEA's cancer related activities. Inthis role, PACT assists countries to developcomprehensive national cancer control plans,following WHO guidelines, and works tosynchronize the efforts of the IAEA, WHO andother partners, supporting cancer care andcontrol around the world.

    To ease the suffering of those who have been,and will be, touched by cancer, PACT hascontinued to be innovative in its approachto support the cancer control efforts of lowand middle income countries. This innovationcomes through PACT's core strategy, whichis designed to assist developing nations toassess their cancer burden, establish thepartnerships needed to create an effectivecancer control plan and provide the trainingnecessary to make cancer control planning a

    success.

    The global outreach of the IAEA provides theprogramme with a unique understandingof the cancer burden faced by developingnations all over the world, and offers anunmatched opportunity to make a profounddifference in the global struggle againstcancer.

    Iaea's programmeof actIonfor cancer therapy

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    why pact

    Cancer is increasingly treatable in developed countries, bu

    many developing countries lack the equipment and human

    resources to respond effectively to the growing epidemic o

    this terrible disease.

    Yukiya Amano, IAEA Director General

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    DevelopmentsanD InnovatIons

    why pact?

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    Current CanCerCrisis

    The world is facing a global cancer crisis. Often considered as a richworld disease, cancer is quickly becoming a public health catastrophe for

    countries throughout the developing world. If urgent action is not taken,84 million people will die from cancer in the next ten years.

    Every minute, fourteen people die of cancer.

    Cancer kills more people than HIV/AIDS, tuberculosis and malariacombined.

    Nearly 12.7 million new cancer cases and 7.6 million cancer deathsoccurred worldwide in 2008. Of these, more than half of the new cases,and nearly two thirds of deaths, were in developing countries.

    More than a third of cancers can be prevented and a third can be cured

    if detected early and treated properly. In developing countries, 70% of cancer cases are diagnosed too late to

    be successfully treated.

    current cancer crIsI

    84 millionpeople, mostof them in

    developing

    countries, willdie of cancer

    in the next

    10 years

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    DevelopmentsanD InnovatIons

    Meeting Muzne

    Muzne Abubakar Haibar, a 40year old mother of four, comesfrom Zanzibar, a picturesquegem of an island known for itsbeautiful beaches and stony citycenter. About three years ago,

    Muzne discovered a lump in herbreast, and quickly sought medicatreatment. She was rst diagnosedwith breast cancer at Ocean RoadCancer Institute in 2008, and had apartial mastectomy, performed atthe time. Muzne soon followed upthis treatment with chemotherapyand immediately showed positivesigns that doctors had removed a

    cancerous tissue.Unfortunately, the cancer returnedmonths later, as Muzne began toexperience deep pain within herchest. Her doctors then opted fora full mastectomy and a furtherregimen of chemotherapy.

    I thought I was OK then,she explained, recounting theexperience of losing a breast tosurgery. Muzne described the tollthat her cancer had taken, notjust on her body but on her familyas well. Since Zanzibar is a threehour ferry ride to Dar es Salaam,she needed to be away fromher family for weeks at a timefor surgery, chemotherapy andrecovery.

    Her ght took yet anotherunfortunate turn for the worsewhen doctors discovered thather cancer had metastasized, orspread, to her spine. She nowreceives radiotherapy and remainshopeful that she will pull through.

    current cancer crIsIs

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    current cancer crIsI

    supporting sustainable solutions

    PACT is more than just a programme addressing a vital,

    critical global health need [PACT] focuses on cost

    effectiveness and on building sustainable relationships

    between recipient countries and donors.

    His Excellency, Mr. Glyn T. Davies, Ambassador, Permanent Mission of the United

    tates of America to the IAEA, World Cancer Day, 4 February 2010

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    DevelopmentsanD InnovatIons

    Country OwnershipCommitment from Member States isessential for success. While PACT offersits assistance, governments must takeownership and responsibility for theirefforts to control cancer. To reinforce thisidea, PACT promotes WHO's approachof National Cancer Control Programmes(NCCP) as the most efcient way to controlcancer locally. NCCPs are comprehensivenational programmes that employstrategies that are both cost effective anduniversally benecial. They are developedjointly with, and implemented by,governments working to establish a planfor long term action against cancer.

    Transfer of Knowledge and TrainingEquipment itself is insufcient to addressthe cancer crisis and many countriesrecognize that lack of human resourcesis the greatest obstacle to advancingcancer control capacity. To furtherthe capabilities of developing cancerprogrammes, PACT facilitates access tonumerous training opportunities and is

    working to establish regional training andeducational mentoring networks, bringingother organizations to the country. Thesewill serve to increase the availability ofcancer treatment, the number of cancercare professionals and, eventually, improvecancer survival rates in developingcountries.

    Building RelationshipsLasting partnerships between developingcountries and potential donors or mentorsmerge resources and offer support andfunding beyond what the IAEA is able tooffer on its own. Through establishingregional networks, PACT also providesMember States with the potential to

    support one another in building cancercontrol programmes.

    supportIng sustaInable solutIons

    Saving lives and improvingcancer outcomes indeveloping countries requian immense, long termcommitment to promoting

    long lasting cancer controlsolutions. PACT workscontinuously to supportthese sustainable solutions

    Country ownership

    Transfer of knowledge antraining

    Building relationships

    Source: WHO

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    programmeof actIonfor cancer therapmPACT conducted:

    Afghanistan

    Burkina Faso

    Cte d'Ivoire

    Dominican Republic

    El Salvador

    Georgia

    Guatemala

    Kenya

    MadagascarMalawi

    Mauritania

    Montenegro

    Morocco

    Niger

    Peru

    Republic of Moldova

    Senegal

    Serbia

    Syrian Arab Republic

    UgandaZambia

    ACT Model

    Demonstration Sites:

    Albania

    Ghana

    Mongolia

    Nicaragua

    Sri Lanka

    United Republic of

    TanzaniaVietnam

    Yemen

    Major donor

    ountries*:

    Canada

    Croatia

    Czech Republic

    France

    Hungary

    India

    Korea, Republic of

    Monaco

    New Zealand

    Norway

    Poland

    Spain

    Switzerland

    United States of

    America

    paCt's glob

    * Donor countries to PACT includes countries that have contributed $10 000 or more to PACT Programme, excluding thecash contributions given by the 58 Member States from the 2004 cash surplus, and other donors, such as OPEC Fund forInternational Development, F. Hoffmann-La Roche Ltd, UN Women's Guild and UN Federal Credit Union.

    Country is not yet a full IAEA Member State.

    The boundaries shown on this map do not imply ofcial endorsement or acceptance by the IAEA..

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    DevelopmentsanD InnovatIons

    imPACT reque Algeria Angola Armenia Azerbaijan Benin Bolivia Bosnia and

    Herzegovina Botswana

    Cambodia Cameroon Cape Verde

    Central AfricRepublic

    Chad Colombia Costa Rica Ecuador Eritrea Ethiopia Gabon

    Gambia Haiti Honduras Indonesia Iraq Kazakhstan Kyrgyzstan Lebanon Lesotho Liberia Libyan Arab

    Jamahiriya

    Malaysia Mali Mauritius Mozambique Myanmar Namibia Nepal Nigeria Pakistan Panama Papua New G Paraguay

    Philippines Romania Sierra Leone Sudan Tajikistan Tunisia Uruguay Uzbekistan Venezuela Zimbabwe

    Palestinian

    Authority

    presenCe

    PACT Model Demonstration Site (PMDS) [8]

    Already received a preliminary or full imPACT review [21]

    Planned to receive an imPACT review [53]

    Major donor countries* to PACT

    82 countries have requested assistance to date.

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    programmeof actIonfor cancer therap

    CanCerControl:

    a vital investment

    n developingcountries

    almost 70%

    of women

    with cervical

    cancer will

    not survive

    cancer control: a vItal Investmen

    Cancer causes poverty. Itdecimates savings and robsfamilies of income earners.Already, over 85% of health costs

    in low income countries are paidout of pocket and more than 100million people are pushed intopoverty every year because theyhave to pay for health care. Insome Asian countries, the averagecost of one hospital stay for canceris greater than a farmer's yearlywage.

    Comprehensive cancer controlis the process through whichall areas of cancer control, fromprevention to palliative care, are

    coordinated to reduce the impactof cancer in the community.For comprehensive cancercontrol to be successful, severalcancer components must besynchronized, providing for astrong and unied approach tocancer care.

    P D & u

    Preventionontrolling ancer

    isk Factors

    arly Detectionarly Diagnosis

    and Screening

    Diagnosis & reatmentFollow-p and ehabilitation

    (Pathology, Radiology and

    Nuclear Medicine, Radiotherapy,

    Chemotherapy, Surgery, Other)

    Palliative areSymptom ontrol & Manage

    (Opiates and adiotherap

    Psychosocial and spirital s

    Bereavement spport for fa

    and caregivers

    Mltidisciplinary dcation, ancer raining and esearch(dvocacy, Pblic dcation, Policy, egislation and esorce Mobilization)

    ancer pidemiology and Srveillance System

    ancer Knowledge ransfer and echnology valations

    dministrative, Financial and echnical apacity to Manage the Programme

    Poplation based ancer ontrol Programmes(WHO Gidelines on Planning, Management and valation)

    Integrated System for Comprehensive Cancer ControlMaximize the Impact of Interventions inclding

    adiotherapy throgh Balanced Investments across the System

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    DevelopmentsanD InnovatIons

    cancer control: a vItal Investment

    On a larger scale, the sheer numberof cancer cases and deaths impact thenational economy. The World Bank notesthat the cost of chronic diseases, such ascancer, ranges from 0.02 to 6.77% of GDP.Another estimate found that a 1% increasein the rate of chronic disease correspondsto a 0.05% decline in economic growth.

    Much of this cost is avoidable. Investmentsin comprehensive cancer control canreduce the cost to both individuals and

    governments. Currently, in developingcountries, more than two thirds of cancerpatients are diagnosed very late, makingthem complex and expensive to treat.Taking action in cancer prevention willreduce the number of cancer cases, andearly detection programmes can ensurethat cancers are found earlier and treatedat a lower cost. Of course, some of thereturns on investment in cancer control arepriceless they relieve suffering and savelives.

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    hoW paCt helps

    To lessen the burden of cancerin the developing world, PACTemploys several different strategiesand approaches, each with specicmethods and objectives.

    how pact help

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    DevelopmentsanD InnovatIons

    Fighting Cancer with Understanding

    To better understand the cancer issues facingthe developing regions of the world, PACTand its partners have developed innovativeassessment tools to enable Member Statesto analyse their cancer burden. Through theintegrated missions of PACT (imPACT) reviews,

    the status of policies, plans and infrastructurerelated to all areas of cancer control areexamined by a multidisciplinary team, in orderto develop intervention packages that respondto each country's specic needs.

    To ensure long term success, imPACT reviewmissions are carried out by experts fromIAEA/PACT, WHO and other internationalpartners, only in Member States that requestassistance and are committed to advancing

    their nation's ght against cancer. In the pastsix years, PACT has performed cancer controlassessments in almost 30 countries in Europe,Asia, Africa and Latin America, with about 50additional countries requesting cancer needsassessments.

    Fighting Cancer with Partnerships

    To illustrate the benets of collaboration onnational cancer control programmes, PACT has

    established global models for action, calledPACT Model Demonstration Sites (PMDS).PMDS receive assistance in the design,implementation and evaluation of nationalcancer control plans and are given support inresource mobilization, to advance all aspectsof cancer control in a timely and balancedmanner.

    These sites demonstrate the potential that alldeveloping nations have to achieve greater

    success in the struggle to control cancer. Thisprovides low and middle income countrieswith not only a solid example from which tolearn, but also hope in knowing that othernations overcame difcult circumstancesto achieve improving cancer standards andoutcomes. PACT currently maintains eightPMDS, located in Africa, Asia, Latin America

    and Europe. Four additional PMDS arebeing considered to make a total of 12 pilotcountries.

    Fighting Cancer with Training forHealth Professionals

    One of the most commonly overlooked

    aspects of effective cancer control is thetraining of individuals capable of providing themedical care needed in developing areas. InAfrica alone, there is a shortage of nearly 3000cancer care workers. To reduce this shortage,PACT and its partners have launched theVUCCnet initiative. This initiative establishesa Virtual University for Cancer Control and asupport networkof recognized regional cancetraining and mentoring centres.

    The aim of this programme is to increase thenumber and capacity of cancer professionalsby providing low cost distance learningopportunities for prospective healthprofessionals in participating countries. Theseeducational efforts are provided in additionto practical training and regional certication.The VUCCnet, nancially supported by theUSA, the IAEA and the private sector, iscurrently in its pilot phase in Africa, with futureplans to expand the programme throughoutthe developing world.

    how pact helps

    Source: Globocan 2008

    developing countries

    developed countries

    BREAST

    268 879 189 488 241 969 33 159

    CERVIX

    deaths annually

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    InnovatIon

    PACT established the AdvisoryGroup on increasing access toRadiotherapy Technologies indeveloping countries (AGaRT)in 2009. AGaRT brings togetherradiotherapy users in low and

    middle income countries,international organizations andexperts, and major radiotherapyequipment manufacturers toensure that developing countries'radiation medicine requirementsare met by the diagnosticand therapy equipment beingproduced.

    The Advisory Group providesan unprecedented platformthrough which all partiescan voice their concerns andrequirements, establishing amutual understanding between

    radiotherapy users and suppliers.It addresses issues of cost, safety,availability and complexity toprovide the developing worldwith machines that are affordable,reliable, safer and easier to use,making the spread of radiationmedicine as wide as possible.

    Some of themost commoncancer typesave high cure

    rates whenetected earlyand treatedaccording tobest practice

    innovationsPACT prides itself on not only utilizing the latest advances incomprehensive cancer control expertise, but also on generating its ownapproaches to further extend the reach of cancer control efforts.

    Making Radiotherapy Affordable

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    DevelopmentsanD InnovatIons

    Connecting Regional Stakeholders

    As a means to connect Member Statesworking towards the common goal ofcomprehensive cancer care and control,PACT has developed regional cancer trainingand mentoring networks. Through thesenetworks, countries developing cancer control

    programmes can work together with MemberStates in the region who have strong cancerprogrammes, to share relevant knowledge,best practices and positive experiences. Thisprovides Member States with a vehicle to aidin the improvement of cancer care and controlthroughout their region and establishes aforum through which all participating nationscan improve their cancer control capabilities.These networks also provide Member States

    with the power to develop on their own,and become acquainted with strategies thathave worked for other nations sharing similarsettings.

    Providing Cost Effective Training

    Without an adequate number of cancercontrol professionals, there is no hope ofproperly preventing and curing cancer, even ifall the drugs or equipment were available. Theonline learning tool to be developed throughVUCC will facilitate access to cancer control

    education for people in low and middleincome countries that do not have access tothe facilities needed to obtain the trainingnecessary to work in cancer control. Utilizingonline education combined with adequatepractical training helps reduce costs, allowingmore people to be trained; it also combatsbrain drain, by permitting those being trainedto remain in their native country. This costeffective training will help increase the numbe

    of health care professionals in participatingMember States and ease the cancer burdenaround the world.

    InnovatIons

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    programmeof actIonfor cancer therap

    why pact

    Cancer is increasingly treatable in developed countries, bu

    many developing countries lack the equipment and human

    resources to respond effectively to the growing epidemic o

    this terrible disease.

    Yukiya Amano, IAEA Director General

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    DevelopmentsanD InnovatIons

    why pact?

    The increase in cancer in low and middle income countri

    could be described as a misfortune. If we fail to do anythin

    about this situation, which is already upon us, then that

    would be a calamity... It is time to do something. I think th

    PACT programme at the IAEA is an inspiration.

    Dr. Peter Boyle, President, International Prevention Research Institute and formDirector, International Agency for Research on Cancer (2004-2008)

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    programmeof actIonfor cancer therap

    programme hIghlIght

    2004

    IAEA Board of Governors and Member States endorse the creation of

    PACT.

    2005

    World Health Assembly welcomes the PACT initiative and asks theDirector General of WHO to explore the development of a jointprogramme with the IAEA on cancer prevention, control, treatment andresearch.

    Nobel Peace Prize is awarded to the IAEA. A portion of the prize moneyis contributed to PACT.

    2006 African Nobel Laureates Nelson Mandela and Archbishop Desmond Tutu

    voice support for PACT.

    First major meeting of PACT international partners is held.

    PMDS are established in Albania, Nicaragua, Sri Lanka, the UnitedRepublic of Tanzania, Vietnam and Yemen.

    2007

    Over 70 health professionals from developing countries are supportedby PACT to attend international training courses on cancer control.

    Albania, Nicaragua, Sri Lanka, and Yemen hold their rst nationalmeetings on cancer control. The United Republic of Tanzania andVietnam establish national steering committees and working groupsbegin to plan cancer control implementation priorities.

    OPEC Fund for International Development (OFID) donates $500 000 tosupport PMDS, bringing total PMDS pledges and in-kind contributionsto over $2.4 million.

    The Republic of Korea runs a unique fundraising campaign for PACT,contributed to by thousands of individual Korean citizens.

    2008

    PACT mobilizes $13.5 million in long term development loans for cancercontrol in Ghana, funded by OFID and the Arab Bank for EconomicDevelopment in Africa (BADEA).

    All PMDS work on national cancer control planning.

    programme highlights

    Tobacco

    causes

    8090%of all lung

    cancer

    deaths,

    and about

    30% of

    all cancerdeaths in

    developing

    countries

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    DevelopmentsanD InnovatIons

    2009

    A joint Programme for Cancer Control is formally signed between WHO and the IAEA. The rst

    WHOIAEA Steering Committee was held in Vienna in July. PACT organizes a side event at the rst International Conference on Advances in Radiation

    Oncology, which becomes the basis for AGaRT.

    PACT adds Ghana as PMDS.

    2010

    PACT receives a pledge of $4 million from F. Hoffmann-La Roche Ltd and the Roche AfricanResearch Foundation to help launch the pilot phase of the VUCCnet initiative in Ghana, theUnited Republic of Tanzania, Uganda and Zambia.

    PACT has coordinated comprehensive imPACT reviews in 29 countries throughout the world. AGaRT holds its rst meeting in Vienna, paving the way for international collaboration to

    increase the availability of radiotherapy machines worldwide.

    PACT adds Mongolia as PMDS, bringing the total number of model sites to eight.

    programme hIghlIghts

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    programmeof actIonfor cancer therap

    programme hIghlIght

    The PACT programme was built on the principle of taking whatwe have learned, and applying it where we can.

    Ambassador Nancy Goodman Brinkerormer US Ambassador and WHO Goodwill Ambassador for Cancer Control

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    DevelopmentsanD InnovatIons

    achIevement through strategIc partnershIp

    aChievement through

    strategiC partnership

    One of the most unique aspects of the PACT programme is its focus on partnership to achieve thebest possible results in furthering the global campaign to control cancer in the developing world.Since its inception, PACT has been devoted to forging partnerships with all organizations workingto ght cancer, from WHO to private sector corporations.

    PACT believes in the strength and effectiveness of a partnership approach, as the global cancercrisis demands coordinated action. PACT is proud to have shaped strong partnerships with:

    WHO and its regional and country ofces, including a WHOIAEA Joint Programme onCancer Control.

    International Agency for Research on Cancer (IARC). International Union Against Cancer (UICC) and International Network for Cancer Treatment

    and Research (INCTR).

    National cancer institutes in Brazil, Egypt, France and the USA, and Tata Memorial Centre(India).

    NGOs, including the American Cancer Society (ACS), Breast Health Global Initiative (BHGI),PATH, National Foundation for Cancer Research and the Lance Armstrong Foundation.

    Private sector, including the Roche African Research Foundation and Best MedicalInternational, Inc.

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    programmeof actIonfor cancer therap

    how you can hel

    Small investments can make a big difference. Donating to cancer control indeveloping countries delivers real results to the people that need it most.Every dollar counts.

    Less than $1 is needed to pay for one outpatient visit for chemotherapy.

    $3 covers the cost of a PAP smear, helping to detect cervical cancer early

    $10 will provide for one complete HPV examination in low incomecountries, preventing cervical cancer.

    $100 can relieve pain for a month by providing a 30 day supply ofmorphine.

    $350 pays for the complete costs of breast cancer treatment in Asiancountries.

    $1500 is the total cost per life saved with radiation therapy in Nigeria.

    $5000 covers the cost of training a radiotherapist.

    $50 000 covers the cost of one imPACT mission.

    $450 000 is the cost of one basic radiotherapy machine.

    $500 000 extends the VUCCnet distance learning apparatus to fouradditional African Member States.

    $5 000 000 covers one cancer centre, including all necessary equipmentand staff, capable of treating hundreds of patients per year.

    hoW you Can help

    Only 3.1% of

    the$285 billion

    spent annuallyon global

    cancer caregoes to

    developingcountries

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    DevelopmentsanD InnovatIons

    Didyou

    know

    veryinteresti

    cancer

    factoid

    blank

    This page is intentionally left blank.

    Cancer is a serious problem in developing countries; it shouldbe recognized as a vital part of the global health agenda.

    Yukiya AmanoIAEA Director General

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    programmeof actIonfor cancer therap

    For more information about PACT or to ndout more about becoming a PACT partneror donor, please contact:

    Massoud SamieiPACT Programme DirectorInternational Atomic Energy AgencyVienna International Centre

    P.O. Box 1001400 Vienna, Austria

    Tel.: (+43 1) 2600 22327/22328Fax: (+43 1) 2600 7 22328

    Printed by the IAEA in AustriaSeptember 201010-3859

    United

    Against

    Cancer