Over Testing in Cancer Staging

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Jon Tilburt, MD General Internal Medicine Mayo Clinic Over Testing in Cancer Staging

Transcript of Over Testing in Cancer Staging

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Jon Tilburt, MD General Internal Medicine

Mayo Clinic

“Over Testing in Cancer Staging”

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Too Big, Too Little Too Hot, Too Cold Too Soft, Too Firm

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“Just & Right Cancer Care”

Fair, sustainable and focused on individual needs

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Desire Hope

Fear

Suffering Progress

Technology

Disappointment

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Moral Danger of Cancer Care

“care” ≈ consumer goods Genuine concern ≈ more testing

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Objectives l  What is cancer staging l  Why is it important l  What does it involve l  Can “too much” ever be bad l  What do the guidelines say for specific cancers

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Cancer Staging

l  How far is it spread l  What treatments are likely to work l  State (0), 1, 2, 3, 4 l  “T” – Tumor l  “N” l  “M” l  “X”

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Staging Importance

l  How do we balance ALL risks & benefits l  Knowing approximate extent – always

important l  If cancer is spread to other parts of body,

surgery may not benefit (harm>help) l  Knowing exact extent varies (dynamics)

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Knowing Exactly Depends On

A.  “Dynamics” B.  How fast growing the tumor is C.  How good our drugs are D.  How toxic cutting would be to get them out

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Factors Influencing Doctors

l  “Would it change my management?” l  How well do doctors deal with uncertainty? l  “What are my incentives?” l  “What are my fears?”

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Staging: What does it involve?

l  History & Physical l  Blood tests l  Biopsy review l  Basic X-Rays/ CT scans l  What else?

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PET Scan

Positron Emission Tomography •  A type of imaging test •  Uses a radioactive substance called a “tracer” to look for

disease in the body •  Shows how organs and tissues use energy •  A more precise test to find tumors

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Can Too Much Staging Be Bad?

l  Little direct individual harm (from test) l  Can cause timing delays l  Can lead to “over-reacting,” but… l  Can help avoid any unnecessary treatment

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What You Need to Know Exactly

l  Likely an aggressive tumor has spread l  Drugs are less effective l  High risk surgery

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Lung Cancer

l  Aggressive tumor l  Drugs aren’t as effective l  Surgery pretty rough l …need to know exact intent of spread

(Stages I-III)

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Breast Cancer

l  Cancer aggressiveness, variable l  Drugs are typically more effective, more

options for recurrences l  Risk of surgery lower l …PET reserved for high risk

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Prostate Cancer

l  Drugs can control & not cure l  Risks of surgery are intermediate l  Typically slower growing l …PET reserved for high risk

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Colon Cancer

l  Drugs are pretty effective l  Risks of surgery are intermediate l  Metastatic disease curable l …PET not routinely needed

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The Data

l  Minimal data on influence of intensity of staging on long term outcomes

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The Guidelines

l  NCCN l  Choosing Wisely

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Disparities & Overtesting

l  “Haves” & “have nots” dynamic l  Temptation for more l  Fear l  Consequence #1: Less aggressive treatment l  Consequence #2: Overly aggressive,

outdated treatments

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Patient-Centered Cancer Care

l  Help patients know they are “worth it” l  Without counterproductive testing

Arthur Frank. Patient-Centered care as a Response to Medification. Wake Forest Law Review. Nov. 2010, p. 1453-1459

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Thank You

[email protected]

@DrJonTilburt