Otics & Flushes Shampoos, Sprays & Wipes...3 Kirk’s Current Veterinary Therapy XV. John D....
Transcript of Otics & Flushes Shampoos, Sprays & Wipes...3 Kirk’s Current Veterinary Therapy XV. John D....
DERMALLAY™ Oatmeal Shampoo 12 oz, GallonDERMALLAY™ Oatmeal Spray 8 oz, 12 oz, Gallonhydrolyzed oat protein, safflower oil (linoleic acid), ceramidesMild pruritus; Itchy, Dry, Sensitive skin
DERMALYTE™ Shampoo 1 oz (60 ct case), 12 oz, Gallonnatural coconut oil, safflower oil (linoleic acid), sodium lactate, glycerine, ceramidesFor normal, sensitive or dry skin; Frequent bathing, Hypoallergenic
HYPOALLERGENIC Cream Rinse 8 ozglycerine, safflower oil (linoleic acid), ceramides For sensitive or dry skin, Frequent bathing, Hypoallergenic
MALACETIC® Shampoo 12 oz, 16 oz, GallonMALACETIC® Spray Conditioner 8 oz, 16 ozMALACETIC® Wet Wipes 25 ct, 100 ct2% acetic acid & 2% boric acidMild fungal & Bacterial infections; Mild pyoderma & Malassezia
DERMABENSs™ Shampoo 12 oz, Gallon2.5% benzoyl peroxide, 1% sulfur, 1% salicylic acid, ceramidesDeep pyoderma & seborrhea oleosa, complements Demodex therapy
MALACETIC® ULTRA Shampoo 8 ozMALACETIC® ULTRA Spray 8 oz1% acetic acid, 2% boric acid, 1% hydrocortisone, 0.15% ketoconazole, ceramidesFungal & bacterial infections, Pyoderma & Malassezia, Inflammation, Pruritus
MALACETIC® HC Wipes 25 ct1% hydrocortisone, 1% acetic acid, 1% boric acid, ceramidesModerate to severe pruritus, Inflammation
MICONAHEX+Triz™ Shampoo 8 oz, 16 oz, GallonMICONAHEX+Triz™ Spray 8 oz, 16 oz, 32 ozMICONAHEX+Triz™ Wipes 50 ct2% miconazole, 2% chlorhexidine gluconate in USP tris-EDTA, ceramidesMild, moderate, and/or severe fungal & bacterial infections, Recurrent infections secondary to atopy and barrier defects
MAL-A-KET™ Shampoo 8 oz, GallonMAL-A-KET™ Wipes 50 ct2% chlorhexidine gluconate, 1% ketoconazole, 2% acetic acidSevere fungal & bacterial infections
MAL-A-KET™ Plus TrizEDTA Spray Conditioner 8 oz2% chlorhexidine gluconate, 1% ketoconazole in USP tris-EDTAFungal & bacterial infections
TrizCHLOR™ 4 Shampoo 8 oz, GallonTrizCHLOR™ 4 Spray 8 oz, 16 ozTrizCHLOR™ 4 Wipes 50 ct4% chlorhexidine gluconate in USP tris-EDTAFungal & bacterial infections; Pyoderma
TrizCHLOR™ 4 HC Shampoo 8 ozTrizCHLOR™ 4 HC Spray 8 oz4% chlorhexidine gluconate, 1% hydrocortisone in USP tris-EDTA Fungal & bacterial infections, Pyoderma, Pruritus, Inflammation
Active
IngredientsAnti-
BacterialAnti-
FungalAnti-
PruriticDewaxing Drying,
DegreasingKeratolytic/
KeratoplasticSkin Repair
Therapy
Acetic Acid x x x x
Boric Acid x x x x
Ceramides x x
Chlorhexidine x x*
Hydrocortisone x
Ketoconazole x
Propylene Glycol
x x x
Salicylic Acid x x
Squalane x
TrizEDTA x
Active
IngredientsAnti-
PruriticAnti-
BacterialAnti-
FungalAnti-Seborrheic/
Keratolytic/Keratoplastic
Drying, Degreasing
Follicular Flushing
Skin Repair Therapy
Acetic Acid x x x
Boric Acid x x x
Benzoyl Peroxide
x x x x x
Ceramides x x
Chlorhexidine x x*
Hydrolyzed Oat Protein
x
EFAs x x
Hydrocortisone x
Ketoconazole x
Miconazole x x
Salicylic Acid x x
Sulfur x x x x
TrizEDTA x
TrizEDTA™ Aqueous and Crystals Flush 4 oz, 16 oztromethamine (tris) USP, edetate disodium dihydrate (EDTA) USPOtitis externa, Bacterial otitis, Pseudomonas
KLEAROTIC™ Ear Cleanser 4 oz22% squalaneRoutine cleansing, Ceruminolytic
EPIKLEAN™ Ear Cleanser 8 oz, 12 oz, 32 oz propylene glycol, salicylic acidRoutine cleansing, Drying, Swimmer’s ear
TrizULTRA™ + KETO Flush 4 oz, 12 oz0.15% ketoconazole in USP tris-EDTAFungal & Bacterial infections
TrizCHLOR™ Flush 4 oz0.15% chlorhexidine in USP tris-EDTABacterial infections
MAL-A-KET™ Plus TrizEDTA Flush 4 oz, 12 oz0.15% ketoconazole, 0.15% chlorhexidine gluconate in USP tris-EDTAFungal & Bacterial infections
MALACETIC® Otic Cleanser 4 oz, 8 oz, 16 oz2% acetic acid, 2% boric acidOtitis externa, Malassezia otitis, Bacterial otitis
MALACETIC® ULTRA Otic Cleanser 2 oz, 8 oz1% acetic acid, 2% boric acid, 1% hydrocortisone, 0.15% ketoconazole, ceramidesPruritus, Inflammation, Otitis externa, Malassezia otitis, Bacterial otitis
Otics & Flushes Shampoos, Sprays & Wipes
Shampoos, Sprays & WipesTo aid in the treatment of conditions listed with each product.
DERMATOLOGY PRODUCT GUIDE DERMATOLOGY PRODUCT GUIDE
Otics & FlushesTo aid in the treatment of conditions listed with each product.
Supplements EICOSA3FFTM SnipCaps Omega 3 Free SMALL <60lb 60 ct, 120 ct Fatty Acid Capsules LARGE >30lb 60ct, 120 ctEPA 262 mg, DHA 172 mg per SMALL SnipCapEPA 515mg, DHA 338 mg per LARGE SnipCapOmega-3 Fatty Acids as free fatty acid form and in a convenient SnipCapAtopic dermatitis, Dry skin or coat, Allergies, Inflammation, Organ health
EICOSACAPS™ Omega 3 & 6 Capsules <40 lbs, 60 ctEICOSACAPS™ L Omega 3 & 6 Capsules 41-70 lbs, 60 ctDry skin or coat
EICOSADERM™ Omega 3 Liquid 8 oz, 32 ozEPA 360 mg, DHA 240 mg per 2 mL Atopic dermatitis, Dry skin or coat, Allergies, Inflammation, Organ health
EPITREATS™ Healthy Canine Snacks 8 ozdried potato product, hydrolyzed chicken liverSemi-moist diet complement for dogs with skin sensitivities, Hypoallergenic
ANIMAX® OINTMENT 7.5 mL, 15 mL, 30 mL, 240 mL(nystatin - neomycin sulfate - thiostrepton - triamcinolone acetonide ointment)
LIMEPLUS™ Dip 4 oz, 16 oz, Gallon97.8% sulfurated lime solution
MURICIN® (mupirocin 2%) Ointment 15 gram Tube
GENTACALM™ Topical Spray 60 mL, 120 mL(gentamicin sulfate with betamethasone valerate)
Anti-Infectives
Label Color Code Guide: General Cleansing/Antipruritic Antimicrobial/Antiseborrheic Antibacterial/Antifungal
*at >3%Caution is recommended when using chlorhexidine in the ear when the status of the tympanic membrane is unknown.
*at >3%
Dechra 24-Hour Veterinary Technical Support(866) 933-2472 | www.dechra-us.com | [email protected]
DermatologyPRODUCT GUIDE
Chlorhexidine Gluconate
TrizEDTA Technology1
• Patented USP Tromethamine-Disodium Edetate (tris-EDTA)• Effective against Gram-negative bacteria • Chelates minerals in bacterial cell walls thereby increasing their susceptibility
to active ingredients in topical products• Alkalinizing• Non-ototoxic• Topical use for dogs, cats, and horses
KetoconazoleA synthetic antifungal drug used to prevent and treat fungal skin infections
Patented Acetic & Boric Acid formulation
• Generally used as adjunctive therapy for bacterial skin infections caused by Gram-positive and Gram-negative bacteria1
• Considered to have residual effects and can remain active on skin after rinsing1
• Bacteria do not tend to develop resistance towards chlorhexidine gluconate• Antifungal properties in concentrations greater than 3%
HydrocortisoneProvides anti-pruritic and anti-inflammatory properties
• Cleansing, drying, acidifying, whitening• Degreasing, deodorizing• Balances skin surface pH making it unfavorable for the overgrowth of
fungus/yeast• Ceruminolytic, keratolytic, keratoplastic, and astringent actions2
• Introduction of TrizEDTA into the bacteria’s environment leads to the release of lipopolyscaccharides, proteins, and phospholipids from the cell wall increasing susceptibility to active ingredients.
• TrizEDTA lowers the bacterial minimum inhibitory concentration (MIC) or, how much of an active ingredient is required to inhibit an organism’s growth.
Outer bacterial cell wall membrane comprised of lipopolysaccharides, proteins, and phospholipids
• A synthetic antifungal used to prevent and treat fungal skin infections• Activity against some gram-positive bacteria, including methicillin-sensitive
and -resistant Staphylococci 3
Miconazole
1 Koch, S.N. (2012). Canine and Feline Dermatology Drug Handbook. Ames: Wiley-Blackwell2 Susceptibility of Selected Otitis Externa Pathogens to Individual and Mixtures of Acetic and Boric Acids. Benson CE - 4th Proceedings of AAVD/ACVD meeting, 1998. Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania.3 Kirk’s Current Veterinary Therapy XV. John D. Bonagura, David C. Twedt Elsevier Health Sciences, 2013
Dechra Veterinary ProductsDERMATOLOGY RANGE TECHNOLOGIES
CeramidesAid in moisturizing, repairing, and restoring dry, damaged skin
Allergies and the Atopic Patient
1. Allergens Enter the Skin...
5. The pet begins to scratch, lick, chew, etc. to relieve the itchiness. This can lead to secondary infections and other skin issues.
2. ...Triggering the Immune System to Respond
3. Mast cells release histamines and other inflammatory mediators.
4. Skin becomes pruritic (itchy).
Ceramides help restore moisture in the skinand aid in rebuilding the epidermal barrier
• Ceramides play an essential role in the structure and maintenance of the bar-rier function of the skin. Proper barrier function is necessary to prevent water loss and the entrance of allergens.
• Findings suggest that decreased amounts of ceramides in the skin of dogs with atopic dermatitis may be involved in the impaired barrier function of their skin.4
• Formulations containing lipids identical to those in skin and, in particular, some ceramide supplementation may improve skin conditions caused by impaired barrier function.
4 Characterization and quantification of ceramides in the nonlesional skin of canine patients with atopic dermatitis compared with controls. Lisa V. Reiter, Sheila M. F. Torres, Philip W. Wertz, Veterinary Dermatology, Volume 20, Issue 4, pages 260–266, August 2009
GENERAL CLEANSING/ ANTIPRURITIC
ANTIBACTERIAL/ ANTIFUNGAL
ANTIMICROBIAL/ ANTISEBORRHEIC
ANTI-INFECTIVES
Dechra Veterinary Products US and the Dechra D logo are registered trademarks of Dechra Pharmaceuticals PLC.May 2015