Order of Events: Small Intestine stomach esophagus large intestineanus small intestine Mouthpharynx.
-
Upload
frank-davidson -
Category
Documents
-
view
229 -
download
0
Transcript of Order of Events: Small Intestine stomach esophagus large intestineanus small intestine Mouthpharynx.
Order of Events: Small Intestine
stomach
esophagus
large intestine anus
small intestine
Mouth pharynx
3
Small Intestine Functions• Lined with villi and
microvilli to increase surface area and absorption of nutrients
• Completes digestion of food
• Receives secretions from the pancreas and the liver to aid in digestion
Villi in the small intestine
Small Intestine: Enzymes• Enzymes from the small intestine include
Proteases=break down amino acid chains into amino acids• Carbohydrases =
break down disaccharides into monosaccharides
7
Small Intestine: EnzymesExamples of Carbohydrases and proteases
Enzyme FunctionSucrase
Maltase
Lactase
Protease
Digests sucroseDigests maltoseDigests lactose
Breaks down dipeptides into amino acids
8
Small Intestine •All types of foods are digested here!
Burger link
Did you notice that most of the chemical
digestion and absorption of food
molecules occurs in the SMALL INTESTINE?
9
A quick review of the digestive system:
Video on the digestive system
Look at the digestive system from Inside with Dr. Oz!
Order of Events: Large Intestine
stomach
esophagus
small intestine
anuslarge intestine
Mouth pharynx
12
Large Intestine• Shorter than the small
intestine (approximately 1.5 m long) but is larger in diameter
• Joins to small intestine through the ilial-caecal sphincter
14
Cecum and Appendix• Cecum = small pouch at the
beginning of the large intestine
• Appendix = a small projection on the cecum– A vestigial organ (no longer
needed in humans)– Found in herbivorous
mammals for cellulose digestion
16
Functions of the Large Intestine1. absorb water, vitamins and minerals into
blood2. Bacteria aid in digestion and help synthesize
(make) vitamin K3. Store undigested materials from digestive
tract
http://www.youtube.com/watch?v=k_WKdrFVBFg&safety_mode=true&safe=active
Bill Nye on the small and large intestine: Beg – 1:54 and 3:29- 6: 35 (peristalsis and chyme)
17
Why is a diet high in fiber important to maintain good health?
• Humans do not have the enzyme cellulase to digest fibre
• BUT we still need fibre!– fiber in the diet helps
retain water throughout the digestive tract resulting in soft feces
18
• Fiber-rich foods work wonders in the body, regulating blood-sugar levels, reducing the risk of coronary heart disease, stroke, hypertension, diabetes, obesity, breast cancer, colon cancer and gastrointestinal disorders such as reflux, duodenal ulcer, irritable bowel and diverticulitis (inflammation of abnormal pouches in the wall of the large intestine or colon), and also supporting weight loss.
20
Rectum & Anus• Last part of digestive
tract• Feces is stored in the
rectum and exits through a sphincter muscle called the anus
anus
rectum
Caution!!!!!
The Next Slide is for Mature Audiences only !!!!!!
Rectum & Anus
Hemorrhoids are formed when veins near the rectal opening become inflamed and swollen
25
Accessory Organs in DigestionLabel and colour the following diagram showing the accessory organs of digestion
liver
gallbladder
pancreas
26
Accessory Organs in DigestionLiver•Produces bile (a brown fluid) which is then stored in the gallbladder
27
Liver and Bile
1) Large fat globule (small intestine)
bile
2) Smaller fat globules (small intestine)
• Bile = a fluid produced by the liver to help emulsify (physically break down) fats– Provides more surface area for lipase to work
lipaselipase
lipaselipase
• Gallbladder– Stores bile (made by the liver) and secretes bile
into the small intestine
28
Gall Bladder
29
• The pancreas secretes pancreatic juices to aid in digestion
• Pancreatic Juices contain: (ALTA) acronym
– Alkaline salts– Lipase– Trypsin– Amylase
Pancreatic Juice
30
Pancreatic Fluid Secretions
Function of Secretion
Alkaline salts (NaHCO3 – sodium bicarbonate)
•Secretin from small intestine goes to pancreas through the blood stream and stimulates the pancreas to release bicarbonate ions•These ions go to the small intestine through the pancreatic duct where they buffer/neutralize the HCl from the stomach•Raises pH to 8
31
Pancreatic Fluid Secretions Function of Secretion
Lipase •Enzyme digesting lipids (triglycerides) into fatty acids & glycerol
Protease (Trypsin)
•Enzyme secreted in inactive form (trypsinogen) which continues protein digestion•Activated by alkaline (basic) pH
Pancreatic Amylase
•Enzyme which continues the digestion of starch into maltose units (completes the digestion that started in the mouth)
32
The Liver• The liver is the largest organ
in the body• Receives blood from 2
supplies
– hepatic artery•oxygen rich blood
from heart– hepatic portal vein
•nutrient rich blood from intestinal walls
33
The Liver• liver acts as a
“gatekeeper” to absorb nutrients from the blood– the liver removes
excess nutrients in the blood
34
Digestive Function of the Liver1) Digestive
Function– Production of bile
which emulsifies (breaks down) fats, which increases the surface area for lipase to act on
– Bile is stored in the gall bladder
Liver
gallbladder
35
Regulatory Functions of the Liver2a) Regulation of Blood Glucose
– removes excess glucose from blood after meal and converts it to glycogen
– once glycogen stores are full, it converts extra glucose into fat which is released from liver into the blood and stored in adipose tissue
when blood sugar levels fall, liver converts glycogen back into glucose and releases it into blood
36
Regulation of Blood Glucose• Other hormones involved (from the
pancreas)• To store glucose from foods we eat,
the liver relies on two hormones produced by the pancreas
– Insulin (converts glucose to glycogen for storage)
– Glucagon (converts stored glycogen into glucose as needed)
38
Other Regulatory Functions of the Liver• 2b) Other Regulatory
Functions• In addition to storing
glucose as glycogen, the liver also stores vitamins and minerals
• The liver takes up and stores fat soluble vitamins such as A, D, E, and K and inorganic minerals such as iron
39
3) Synthesis of Plasma Proteins– manufactures important
blood proteins – Examples:
•Fibrinogen (for blood clotting)
•albumin•globulin
Regulatory Function of the Liver
40
Other Excretory Functions of the Liver4) Excretory Functions
Breakdown of old Red Blood Cells• the pigment is excreted in bile• the iron is stored for future RBC’sDetoxification• liver breaks down poisons and non-
food substances in blood• e.g.: alcohol, caffeine, nicotine, drugs,
excess hormonesProduction of urea• deamination (breakdown) of excess
amino acids
42
StomachThe stomach absorbs:
– some water– glucose– specific vitamins– alcohol
• After digestion is complete, the simple molecules must be absorbed into the circulatory system or lymphatic system to be carried to the body cells
• The stomach, small intestine, and large intestine play a major role in absorbing required simple molecules
Topic 4-4: Absorption
https://www.youtube.com/watch?v=vkpz7xFTWJo
ASAP Science: Your brain on alcohol 2:13
43
Small Intestine• Once ALL food molecules are at
monomer stage, they are ready to be absorbed into the circulatory system
• Capillaries (blood) absorbs:– monosaccharides– amino acids– vitamins/minerals– water
• Lacteals (lymphatic system) absorb:– lipids
46
Large Intestine• Absorbs water, minerals and vitamins• Any material not absorbed, forms the fecal
material that is removed from the body by egestion
http://www.youtube.com/watch?v=nM5kMSjBrmw
Bozeman Digestion video 9:39
48
Topic 4-6 Disorders of Digestive System
• Cause: Mucous lining of stomach breaks down. Cell membrane is exposed to corrosive acid and pepsin. When cells are destroyed, an ulcer forms.
• Symptoms: pain, especially when eating acidic or hot foods
• Treatments: Lasers remove damaged tissues + seal blood vessels.
Ulcers
49
Gall Stones• Cause: Cholesterol , an insoluble
component of bile, acts as a binding agent for salt crystals found in bile
• Symptoms: Pain. Inflamed and blocked gall bladder can rupture – can be life threatening
• Intense pain below ribcage that can radiate to right shoulder accompanied with loss of appetite & nausea
• Treatment: Removal of gall bladder OR medicines that dissolve gall stones ALSO shockwave therapy.
50
Jaundice• Causes: Blocked bile duct or
accelerated destruction of RBC’s can cause jaundice (can lead to hepatitis). Liver is not functioning properly.
• Symptoms: A sign of the disease is yellow skin and eyes
• Treatments: Diet, therapy or exercise will help. Also fruit juices (minor cases), enemas, drugs and liver transplants (major cases)
51
Appendicitis• Cause: Inflammed appendix• Symptoms: Pain in lower right
abdomen, accompanied by fever, vomiting
• Treatments: Removal of appendix