Oral Contraceptive Initial
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Transcript of Oral Contraceptive Initial
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8/3/2019 Oral Contraceptive Initial
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Characteristics Type of OC Indicated Suggested OC for Initial
Cylces (see table 2)
Regular light menses. 2-4 days flow: mild or
no cramps
Low endometrial activity Groups 3,6,8
Regular moderate menses. 4-6 days flow:moderate cramps
Intermediate endometrial activity Groups 2, 4, 5, 7, 9, 10,11
Regular heavy menses. 6 plus days flow:severe cramps High endometrial activity Group 13
Irregular and infrequent menses,hypermenorrhea whon occurs: associated
acne, oily skin, hirsutism
Probably polycystic ovarian syndrome.High progestional and low androgenic
activity desireable.
Groups 2, 6, 7, 8, 10
Irregular menses, hypomenorrhea when
occurs: no adreogen effects
If galactorrhea present, possible pituitary
adenoma. Skull x-ray or prolactin needed.If no galactorrhea, low estrogen and low
progestational activity combination OCs
or multiphasic OCs may be used
Groups 1, 5, 8 , barrier
and spermicidal methods
Smokers- ages 35+ Combination OCs contraindicated Group 1, barrier and
spermicidal methods
Nonsmokers- 35+ Sub 35 mcg estrogen, intermediate/high
progestin, combination OC
20-25 mcg EE Ocs from
groups 2, 3, 5, 7, 8Weight less than 110 lbs Lower estrogen and low progestin dose Groups 5, 7, 8 or any tri-phasic
Weight more than 160 lbs High estrogen and intermediate to highprogestin
Group 11, 12, 13
Progesterone hypersensitivity: history of
toxemia, stong family history of hypertension,
excessive weight gain, tiredness or variconeveins during pregnancy, depression, excessive
premenstrual edema
Low progestin does and progestational
activity. Monitor blood pressure.
Groups 1, 8, 10
(antimineralocorticoid
activity) or any triphasic
Estrogen hypersensitivity: excessive nausea,
edema or hypotsn in pregnancy,hypertrophy of
cervix or uterus, uterine fibrios, large or
fibrocstic breasts; heavy menses, migraine
Low estrogenic activity Group 1 or any 20 mcg
EE OC
Conditions predisposing to cardiovascular
disease type ii hyperlipidemia (high
cholesterol) diabetes mellitus, obesity,
smoking more than 15 cigarettes per day,
hypertension, varicose veins, thrombophlebitis
during pregnancy, family of cardiovascular
disease before age 50
Combination pills not recommended. Group 1, barrier and
spermicidal methods
Surgery planned within 1-4 weeks Combination pills should be stopped Group 1, barrier and
spermicidal methods
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Group Index name: Generic name Activity
1 Micronor, Nor-QD: Camila, Errin,
Jolivette, Nora-be Ovrette: Lybrel
Endometrial: Low
Progestational: Low
Androgenic: low
2 Mircette: Kariva, Desogen, Ortho-cept:
Apri, reclipsen
Endometrial:Intermediate
Progestational: highAndrogenic: low
3 Loestrin 1/20: Junel 1/20, Microgestin
1/20 Loestrin 1/24: Loestrin 1.5/30; Junel1/50, Microgestin 1.5/30 Estrostep:
Seasonale, Seasonique
Endometrial: Low
Progestational: intermediateAndrogenic: Intermediate
4 LoOvral: Cryselle, Low-Ogesstrel
NordetteL Levlen, Levora, Portia
Endometrial:intermediate
Progestational: intermediate
Androgenic: intermediate
5 Ortho Tri-Cyclen Lo: Ortho Tri-Cyclen:
Triness, Tri-previfem, tri-sprintec Ortho-
cyclen: monessa, privifem, sprintecTraphasil: Enpressse, tri-levlen, trivora
Ovcon 25: Balziva
Endometrial: intermediate
Progestational: low
Androgenic: low
6 Demulen 1/35:kelnor, zovia 1/35 Endometrial: low
Progestational: high
Androgenic: low
7 Cyclwaa: Velivet
Ortho-vovum7/7/7: Nortel 7/7/7Orthonovum 10/11: Necon 10/11, Nelova
10/11
Endometrial:intermediate
Progestational:intermediateAndrogenic:low
8 Alesse: avianna, lessina, levlite, lybrel,
lutera, sronyx Brevicon, modican: necon .5/35, nortral .5/35Tri-norinyl: arnelle
Endometrial:low
Progestational:lowAndrogenic:low
9 Norinyl, ortho-novum 1/35; necon 1/35,
nortrel 1/35
Endometrial:intermediate
Progestational:intermediate
Androgenic:intermediate
10 Yasmin yaz Endometrial:intermediate
Progestational:higheAndrogenic:none
11 Demulen 1/50: zovia 1/50 Endometrial: intermediateProgestational: high
Androgenic: low
12 Norinyl, ortho-novum 1/50M: necon1/50M, Nelova 1/50 M Norlestrin 1/50,
ovcon 1/50
Endometrial: intermediateProgestational: intermediate
Androgenic: intermediate
13 Ovral: ogestrel Endometrial: high
Progestational: high
Androgenic: high
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Taken from:
Managing Contraceptive Pill Patents, Thirteenth edition, by Richard P. Dickey, MD, PhD