Ophthalmic Instruments for Vision Research♦ Clinical Studies ♦ Monitoring Treatment Efficacy ♦ Animal Studies

• Clinical and laboratory research instrument

• AO assisted line scanning ophthalmoscope with brightfield imaging

• Spectral Domain OCT with en-face/montageand 3-D modes

• Near isotropic micron-level imaging of retina, retinalstructures and blood flow

Multi-modal Adaptive-Optics Retinal Imager (MAORI)

• Clinical and laboratory research instrument

• AO assisted Scanning Laser Ophthalmoscope

• Spectral Domain OCT

• Wide-field Line Scanning Ophthalmoscope

• Near isotropic micron-level imaging of retina and retinal structures

• Bright/dark/split field imaging modalities available

Multi-modal Adaptive-Optics Small Animal Imager (MAOSI)• Laboratory research instrument optimized for imaging

rodent eyes

• AO assisted Laser Scanning Ophthalmoscope andSpectral Domain OCT

• High resolution imaging of animal retina

• Enface and cross-sectional in-vivo fundus imaging

• Simultaneous reflectance and fluorescence imaging

• Novel Imaging depth controls and animal stage

♦ Emerging Science♦ Technology Solutions

♦ Innovative ProductsPhysicalSciences Inc.

Compact Adaptive-Optics Retinal Imager (CAORI)

Technical Sales SupportNicusor Iftimia and R. Daniel FergusonPhysical Sciences Inc.Phone: 978.689.0003Email: iftimia@psicorp.com and ferguson@psicorp.com

Technology Transition ManagerWilliam KesslerPhysical Sciences Inc.Phone: 978.738.8253Email: kessler@psicorp.com

PSI’s retinal imager is available for demonstration at PSI. To arrange for a demonstration, inquireabout additional technical details, or to discuss purchase and lease options, please contact us:

PhysicalSciences Inc. 20 New England Business Center, Andover, Massachusetts 01810

Tel: (978) 689-0003 Fax: (978) 689-3232 Website: www.psicorp.com

Physical Sciences Inc. (PSI) is a research and development company nationally renowned for itsinnovation in optical technologies. We are involved in broad areas of science, engineering, andtechnology, and in development of specialized instrumentation for scientific and industrial applicationsincluding biomedical optics research. Our goal is to develop technologies furthering state-of-artcapabilities and scientific understanding and to create new technology solutions. PSI has a successfulhistory of NIH funded research and collaboration with ophthalmic and biomedical researchers.

CAORI and MAORI Retinal Imaging Capabilities

MAOSI Animal Imaging Capabilities

AO-SLO Imaging of Cones & Rods En-face SD-OCT

Close-up DarkField of Vessel

Mean Std. Deviation B-scan SD-OCTAneurysm

Capillaries OCT B-scans Nerve FiberBundles

ONH BloodFlow