Ontogenesis imperfecta
Transcript of Ontogenesis imperfecta
Ontogenesis Imperfecta
By: Charles Xu
Info on OI
• The scientific name of the disease is Lobstein Syndrome.
• OI codes for Collagen I
• As of now there is no treatment for the disease
• The disease is caused by a dominant factor and if neither of the parents have it it’s a spontaneous mutation
More info on OI
• There are 8 types of OI each more sever then the next.
• You can live a normal life depending on the severity and the age.
• It requires great medical care.
Symptoms
• Symptoms include• Bones fracture easily• Short Stature• Hearing loss at a young age• Discolored or brittle teeth• Blue sclera• Weak muscles• And many more
Chromosome that carries OI
The genes have switched parts by crossing over
Pedigree
Bibliography• Tulane University. Web. 16 Apr. 2011. <http://www.tulane.edu/>. • Osteogenesis Imperfecta Foundation: Fast Facts." Osteogenesis
Imperfecta Foundation:. Web. 16 Apr. 2011. <http://www.oif.org/site/PageServer?pagename=fastfacts>.
• "Discovery Health "Living with Osteogenesis Imperfecta"" Discovery Health "Health Guides"Web. 16 Apr. 2011. <http://health.howstuffworks.com/diseases-conditions/musculoskeletal/osteogenesis-imperfecta4.htm>.
• "Google Images." Google. Web. 16 Apr. 2011. <http://www.google.com/imgres?imgurl=http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/T/Translocation_8-14.gif>
• Osteogenesis Imperfecta Symptoms." Bones Home Page. Web. 16 Apr. 2011. <http://bones.emedtv.com/osteogenesis-imperfecta/osteogenesis-imperfecta-symptoms.html>.