ONCODEATHONCODEATHSensitization and resistant Sensitization and resistant

determinants of cancer cells to death determinants of cancer cells to death receptor related therapiesreceptor related therapies

Contract No: LSHC-CT-2006-Contract No: LSHC-CT-2006-037278037278

Kick off meetingKick off meeting

Athens, 1 December 2006Athens, 1 December 2006

ContractContract Details (1)Details (1)

Specific Targeted Research ProjectsSpecific Targeted Research Projects Started date: 1Started date: 1stst November 2006 November 2006 Duration: 36 monthsDuration: 36 months Community financial contribution: Community financial contribution:

2,344,900.002,344,900.00€€

Contract Details (2)Contract Details (2)

Reporting periods:Reporting periods: P1: From month 1 to month 12P1: From month 1 to month 12 P2: From month 13 to month 24P2: From month 13 to month 24 P3: From month 25 to the last month of the P3: From month 25 to the last month of the

projectproject Reports submission:Reports submission:

P1 – period P1 & P3 – periods P2 + P3P1 – period P1 & P3 – periods P2 + P3 Within 45 days from the end of the Within 45 days from the end of the

reporting periodsreporting periods

Contract Details (3)Contract Details (3) Community financial contribution: Community financial contribution:

Paid to the Paid to the coordinatorcoordinator on behalf of the on behalf of the contractors – Distributed as soon as possiblecontractors – Distributed as soon as possible

Payments:Payments: Pre-financing: 938,108.00Pre-financing: 938,108.00€€ - within 45 days - within 45 days

from the entry into force of the contractfrom the entry into force of the contract Intermediate payments: Intermediate payments:

With an audit certificate:With an audit certificate: Payment to settle the amounts justified and acceptedPayment to settle the amounts justified and accepted Intermediate pre-financing of 80% to the subsequent Intermediate pre-financing of 80% to the subsequent

period and the next 6 monthsperiod and the next 6 months Without an audit certificate:Without an audit certificate:

Intermediate pre-financing of 80% to the subsequent Intermediate pre-financing of 80% to the subsequent period and the next 6 monthsperiod and the next 6 months

within 45 days from the approval by the within 45 days from the approval by the Commission of the reports – necessaryCommission of the reports – necessary not less not less than 70% of a pre-financing has been usedthan 70% of a pre-financing has been used

AmendmentsAmendments

Necessary the identification of the Necessary the identification of the nature and the details of the requestnature and the details of the request

Submitted in writing only by the Submitted in writing only by the coordinator on behalf of the coordinator on behalf of the consortiumconsortium

Approval or rejection between 45 Approval or rejection between 45 days of its receiptsdays of its receipts

Overall budgetOverall budget

Consortium AgreementConsortium Agreement Based on Model Consortium Agreement Based on Model Consortium Agreement

provided by relevant working-group of the provided by relevant working-group of the EUEU

Main Subjects covered: Main Subjects covered: Organizational and Management StructureOrganizational and Management Structure Party’s responsibilities and authorityParty’s responsibilities and authority Confidentiality Confidentiality LiabilitiesLiabilities Intellectual Property RightsIntellectual Property Rights

Distributed for commentsDistributed for comments

ObligationsObligations

Forms A & A4 – signed and send until Forms A & A4 – signed and send until the end of Decemberthe end of December

Pre-financing paid until 15 of Pre-financing paid until 15 of December 2006 (?) and distributed December 2006 (?) and distributed ASAPASAP

Consortium Agreement signed and Consortium Agreement signed and send until the end of Decembersend until the end of December

Launching of project’s Web Site until Launching of project’s Web Site until …………