OF THE AMERICAN CHEMICAL SOCIETY VOL. 101, NO. 3 …lvacs.sites.acs.org/Octagons/March2018.pdf ·...

NEWSLETTER OF THE LEHIGH VALLEY SECTION MARCH, 2018 OF THE AMERICAN CHEMICAL SOCIETY VOL. 101, NO. 3

VOL. 101, NO. 3, PAGE 1

Next Meeting:

Thursday March 22, 2018 Muhlenberg College

In This Issue:

Meetings and Events 1-3 MoleCVUE 2 Chairs Message 3 Diversity Event 4 Strategic Plan Update 5 Undergrad Poster Session 6 Chem Olympiad 7 Volunteer Award 7

Nano MARM 8 CCEW Contest 9-11 Scholarship 12-13 BCCE 13-14 Cedar Crest Event 15 Chemagination 16-18 2018 Officers 19

THE OCTAGON

MEETING DETAILS: 5:30 - 6:00pm Seegers Union Room 1136:00 - 7:00pm Seegers Union Room 1137:00 - 8:00pm Trumbower Hall Room 1308:00 - 8:30pm LVACS Business Meeting (Collier Hall of Science Room 204)Cost: $25 Faculty/Industry Professionals, $15 Students/Retirees/High School TeachersMenu: Reception: Crudités with Ranch Dip, Pico de Gallo with Tortilla ChipsDinner: Garden Salad with Ranch and Italian Dressings, Bread and Butter, Braised Beef Sicilian, Chicken Florentine, Gnocchi with Asparagus, Shiitake, Pearl Onion, Tomato and White Wine Pesto Broth, Mashed Potatoes, Sautéed Zucchini and SquashChocolate Ganache Tart with Oreo CrustCoffee, Tea, Lemonade, Iced TeaDirections and Parking: http://www.muhlenberg.edu/main/aboutus/directions-to-muhlenberg/Use staff parking behind Trumbower Hall, see http://www.muhlenberg.edu/main/aboutus/tour/map.htmlRSVP: Friday, March 16th, to LuAnn Feist 484 664 3260 [email protected]

Drug Discovery of Neglected Diseases: Slow Kinetics Strategies

http://www.muhlenberg.edu/main/aboutus/directions-to-muhlenberg/

http://www.muhlenberg.edu/main/aboutus/directions-to-muhlenberg/

NEWSLETTER OF THE LEHIGH VALLEY SECTION MARCH, 2018 OF THE AMERICAN CHEMICAL SOCIETY VOL. 101, NO. 3

VOL. 101, NO.1, PAGE 3

March Meeting

Speaker: Brad Haubrich, Ph.D., Bryant University

A graduate of Muhlenberg College, Brad A. Haubrich studied sterol biosynthesis and its inhibition in microorganisms such as Trypanosoma brucei, the etiological agent of human African trypanosomiasis (HAT). After receiving his Ph.D., he continued his medicinal research for HAT and other neglected diseases at the Institute for Rare and Neglected Diseases Drug Discovery in Mountain View, CA. His work has involved inhibitor design and discovery for enzymes of eukaryotic and prokaryotic pathogens. Currently, Dr. Haubrich teaches chemistry and

biology at Bryant University in Smithfield, RI, and researches with Dr. Christopher W. Reid to find new targets and new molecules to fight antibacterial resistance.

TITLE: Drug Discovery of Neglected Diseases: Slow Kinetics Strategies

ABSTRACT: Drug discovery is a lengthy and expensive process, and, despite the time and effort expended to find new medicines, success rates in developing new clinical molecules continue to decline. Molecular mechanisms of action (MMOAs), including binding kinetics and competitiveness, provide mechanistic insight that can help to inform predictions of how therapeutic compounds will behave in vivo. Methods for testing MMOAs early in the drug discovery process can yield future success of lead compounds, and simple, inexpensive methods can provide this insight for medicines against neglected diseases, where time and financial resources are limited. Drug screening with considerations to MMOAs will be discussed, and recent examples highlighted include slow binding molecules to enzymatic targets from Kinetoplastid parasites.

MoleCVUE AnnouncedMoravian College will host MoleCVUE 2018 June 6-8. MoleCVUE is a workshop for exploring educational and research applications of computational chemistry. For more information, contact Carl Salter at 610-625-7920. or [email protected].

NEWSLETTER OF THE LEHIGH VALLEY SECTION MARCH, 2018 OF THE AMERICAN CHEMICAL SOCIETY VOL. 101, NO.3


Spring/Summer 2018 Meetings and events - Mark your Calendars!

Tuesday April 17 DeSales University

Undergraduate Student Research Poster Session and Student Awards Call for Posters in this Issue!

May 2018 Saucony Creek, Date TBA

Thursday, July 26 2018- Iron Pigs

Chairs Message

Hello Members of the Lehigh Valley section! As we finish Black history month and start Women's history month I would like to alert you to an opportunity to learn about the issues facing minorities in the field of chemistry on the 15th of March. The details of the event are found in this issue of the Octagon. I include Women's history month because some of the issues that minorities face are the same issues that woman face in the workplace. While the issues do not overlap completely there is much for the community to learn from these events. More importantly these events sponsored by our Minority affairs committee and our Woman's Chemist Committee are opportunities for all chemists to learn about these issues and how to be involved in addressing them. Please consider attending the events sponsored by our sub committees especially if your name isn't included in the committee. Learning about the issues facing subsets of our community helps the entirety of the Society succeed. Best wishes for your March; I hope to see you on both the 15th for the minority affairs event and the 22nd for our regular monthly meeting.

John Freeman Chair Lehigh Valley section ACS



2018 Chemistry Olympiad The Muhlenberg College Chemistry Department, in cooperation with the Lehigh Valley Section of the American Chemical Society, will be hosting the 2018 Local and National Chemistry Olympiads. The Local Chemistry Olympiad competition will be held at the Muhlenberg College Lithgow Science Auditorium (Trumbower 130) on Saturday, March 17, 2018 from 2:00 pm to 4:00 pm. Student check-in and registration begins at 1:00 pm. Nine local high schools will be represented and 41 students will be participating in the academic competition. The participating schools are: Belvidere HS, Berks Catholic HS, Emmaus HS, Exeter Township Senior HS, Freedom HS, Parkland HS, Southern Lehigh HS, Whitehall HS, Wyomissing JSHS

The USNCO National Examination is on Saturday, April 21, 2018, also at Muhlenberg College. For more information, please contact the chemistry Olympiad coordinator, Dr. Kathleen Herrera of Muhlenberg College at [email protected] or at facebook.com/usncolvacs.

Young named Volunteer of the Year Sherri Young, assistant professor at Muhlenberg College, was named the recipient of the 2018 Local Section Outreach Volunteer of the Year Award for the Lehigh Valley Section of the ACS. Sherri was presented her award on February 21st at the section’s meeting at Moravian College. The award is sponsored by the ACS Committee on Community Activities. Sherri has served the Lehigh Valley section in a variety of ways. In 2017, Sherri was the logistics chair for MARM, serving as a liaison between the meeting venue and the planning committee. Sherri went above and beyond her duties and was instrumental in a successful MARM meeting; Sherri helped organize workshops and a wine-chocolate tasting. Sherri was the co-advisor for Muhlenberg’s student chapter and a co-planner for the “You Be the Chemist Challenge.” She served two terms as treasurer and as the WCC Chair organized luncheons, which were well-attended and first-time events. Congratulations Sherri!



LV-ACS Scholarship for Organic Chemistry

The Lehigh Valley Section of the American Chemical Society will award its annual Scholarship for Organic Chemistry this May. To be eligible, students should be below the junior level, currently enrolled in organic chemistry at an institution in the section, and a chemistry, biochemistry, or chemical engineering major. The competition entails taking the ACS Organic Chemistry Examination (45%), a letter of recommendation from the student’s organic chemistry professor (10%), and an essay on a topic in organic chemistry (45%). The value of the scholarship is $1000. Additionally, the top essay will receive $100. Details about the exam, letter, and essay follow below. Students should indicate their interest in the scholarship in advance of 28 April 2018 to Dr John Freeman, [email protected]

ACS Organic Chemistry Examination: The exam will be administered on Saturday, 28 April 2018, at Moravian College, Bethlehem, PA from 9:00-11:00 AM. Students should report to the entry foyer of the Collier Hall of Science, which is on the Main Street Campus. For driving directions and campus map see http://www.moravian.edu/about/campus/main-street/2. Juice and bagels will be available at 8:45 AM.

Letter of Recommendation: Professors writing a letter of recommendation on behalf of a student who is applying for the Lehigh Valley ACS Scholarship should speak to the student’s skills in lecture and laboratory in Organic Chemistry I and Organic Chemistry II. Please provide the course grade for Organic Chemistry I and comment on performance on written exams, proficiency in organic lab, and participation in recitations, problem sessions or course-related group work. If possible, address the student’s quantitative skills by commenting on her or his performance in quantitative analysis or its local equivalent. The letter of recommendation must be submitted in a sealed plain envelope and signed by the professor over the seal. The student will be required to bring the sealed letter to the ACS Organic Chemistry Exam at Moravian College on 28 April 2018

Essays: The student should choose a molecule, a group of molecules, or a process in organic chemistry to write about. The essay should be written at a level to interest and educate a general chemist who has completed sophomore-level organic chemistry. Synthesis, mechanism and structural elucidation should be covered for the chosen molecule (or representative examples of a chosen group). If a process is chosen, the physical and chemical basis for its success should be explained. Appropriate use of structures to facilitate understanding of the chemistry is expected. The essay should address the impact of the molecule or process on society and the student’s personal interest in it. The essay should run from 1600 to no more than 1800 words in Times New Roman 12 point font with one-inch margins on all sides. This does not include figures. Each page should have a header with the student’s last name, brief essay title and page number. An additional page with references must be included. References should follow the style of The Journal of the American Chemical Society (an article from a recent issue can serve as a model). The winning essay after editing may be published on the section website with a link in the Octagon. Continued on Following Page


VOL. 101, NO.3, PAGE 13

Organic Scholarship Continued The essay will be rated on: • 30% - Appropriate depth of coverage of the molecule(s) or process. • 30% - Appropriate depth of coverage on the impact on society and student’s interest. • 20% - Ease of reading, including grammar, spelling, and logical flow of the material. 10% - Appropriate use of structures and figures. • 10% - Appropriate use of references. • 5% - Penalty for failure to adhere to the formatting rules provided. The student should bring the essay to the ACS Organic Chemistry Exam at Moravian College

25th Biennial Conference On Chemical Education (BCCE) High School Teacher Travel Grant

High school teachers interested in obtaining a travel grant to attend the 25th BCCE at the University of Notre Dame (July 29 – August 2, 2018) need to complete an application by April 1, 2018 and submitted it to: John Freeman 220 W Pierce St, Easton PA 18042:

1) Name and contact information including email and phone number. You will be notified of your award status by March 1, 2018. Please submit contact information based on where you will be during that time. 2) School information. School location, and type. 3) Statement of Support. Submit a 25th BCCE High School Teacher Travel Grant Administrative Statement of Support completed and signed by your school administrator (e.g., principal or superintendent). 4) Proposal. The proposal consists of three sections:

a. Professional Summary & Goals. Briefly summarize your goals for attending the conference. How will you apply or incorporate your experiences within the classroom? How will you share your experiences with your colleagues? Limit your response to approximately 250-300 words or one page . b. Outcomes. How will your attendance improve student learning in chemistry? What learning objectives do you hope to improve or achieve? Limit your response to approximately 250-300 word or one page c. Budget (not to exceed $1,500). The budget should justify the amount requested.


VOL. 101, NO.3, PAGE 14

Travel Grant funds cannot be used to: i. Pay indirect costs, administration fees, salaries, or stipends. ii. Support travel costs or conference fees for more than one person. Each person must apply separately.

The cost of the conference for secondary educators is: Registration $175 Up On-campus double occupancy housing $75 /night" Travel (Up to the IRS Auto Mileage Allowance from City Center Bethlehem to the University of Notre Dame Campus.


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2018 MARM CHEMAGINATION DESCRIPTION AND RULES

CONTEST OVERVIEW

For this event, high school students are asked to imagine that they are living 25 years in the future and have been invited to write an article for ChemMatters, a magazine for high school students that focuses on the role of chemistry in everyday life. The subject of the article is: “Describe a recent breakthrough or innovation in chemistry (and/or its applications) that has improved the quality of people’s lives today.” To view a sample ChemMatters magazine visit acs.org, and look under Education: http://www.acs.org/content/acs/en/education/resources/highschool/chemmatters.html.

In addition to the article, students are asked to design a cover for the magazine. The article must be written as if the student is living in the year 2042, looking back at innovations that have occurred since 2018. The innovation must fall into one of the following categories:

* Alternative Energy * Medicine/Health* Environment * New Materials

A few examples of areas where development is expected are: nanotechnology, energy efficiency, pollution prevention, green chemistry, sustainability, intelligent devices for sensing, proteomics, climate models, biopharmaceutical therapies, medical devices and/or implants and new energy sources.

Evaluation of the entry is based upon: (1) the written article which is submitted in advance, (2) the presentation of the innovation on a self-standing display and (3) knowledge of and soundness of the science as demonstrated in interviews with judges (much like science fair judging).

RULES

ARTICLES must:• be written by a team of two or three students; each student may be on only one team.• be about 1000 words (figure captions are not included in the limit).• present the chemistry/scientific concepts/ideas/principles behind the innovation.• describe the innovation and indicate how it has improved people’s lives.• present a “history” of the changes that had to occur over the prior 25 years to develop this innovation.• include drawings, diagrams, illustrations and descriptions of the chemistry and any technology involved

in all key aspects of the innovation.• cite a minimum of three technical references.• include a cover design for the magazine. The cover design can be an original computer graphic or a free-

hand drawing.

DISPLAYS must:• be not more than 24” deep, 40” wide or 48” tall, and be able to sit on a table, much like at a science

fair display.• include the cover of the magazine.• be a visual representation of the article’s content with a minimum of text. • include a list of references cited.

http://www.acs.org/content/acs/en/education/resources/highschool/chemmatters.html





VOL. 101, NO.3, PAGE 18

ATTENDANCE:• At least one member of the team must attend the contest to present the display and interview with the

judges to be eligible for prizes.

SCORING:• Winners are selected by the judges based on the quality of the article and display, and the quality and

understanding of the science of the innovation. • Criteria for scoring include scientific thought, creativity, clarity, thoroughness and teamwork.

ELIGIBILITY/REQUIREMENTS:• Each local section can submit up to four entries (1 per category).• All students must be currently enrolled in an accredited high school or home school and be

taking or have recently completed a grade 9-12 science class.• Students and their parents are responsible for transportation to and from the meeting site.• All entries become the property of the ACS and will not be acknowledged or returned. • The ACS, its agents and contractors, are not responsible for lost, late, misdirected, or postage-due

entries.• Acceptance of the prize constitutes consent to use the winners’ names, likeness and entries for editorial, advertising, and publicity purposes. • Prizes are not transferable.• Taxes, if any, are the sole responsibility of the winner.• Participants will be asked to provide a Photo Release Form signed by a parent or guardian prior to attending the contest.

KEY DEADLINES

February 6 Local sections notify 2018 MARM Chemagination contest co-chairs of their preliminary intent to participate in 2018 MARM Chemagination.

March 15 Local sections confirm their intent to participate in 2018 MARM Chemagination

May 1 Local Sections submit their estimate of the number of teams they will be sending to the 2018 MARM Chemagination.

May 15 Local sections confirm number of participating teams and submit article titles and contact information on each student. (Submission process will be announced at a later date.)

May 22 Teams submit their articles for pre-judging.

June 3 The 2018 MARM Chemagination competition takes place at the Iacocca Center , on the campus of Lehigh University


VOL. 101, NO.3, PAGE 19

2018 LVACS OFFICERS

Chair: John Freeman [email protected]

Immediate Past Chair: Celia Williams Avantor Performance Materials, Inc. 1013 US Highway 202/206 Bridgewater, NJ 08807 [email protected]

Treasurer: Jonathan Fura Entrepreneurial Scientist Avantor Performance Materials, Inc

Secretary: Seiji Inaoka Director Technology Process Research Products Ewing Township, NJ [email protected]

Chair Elect: Denise Beautreau General Chemistry Laboratory Manager Lehigh University Bethlehem, PA [email protected]

Councilor: Kelley Caflin Picatinny Arsenal Lead Analytical Chemist Energetics Research Branch Armament Research, Development and Engineering Center

[email protected]

Councilor:Jeanne Berk Dept. of Chemical and Physical Sciences Cedar Crest CollegeAllentown, PA 18104 610-606-4666 ext 3507 [email protected]

Alternate Councilor: Greglynn Gibbs Penn State

[email protected]

Octagon Editor & Webmaster: T. Michelle Jones-Wilson East Stroudsburg University East Stroudsburg, PA 18301 [email protected]

mailto:[email protected]



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