Odontogenic Infections 1

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    Diagnosis and Management of

    Odontogenic Infections

    Jeff Lee

    Dept. of Oral and Maxillofacial Surgery1/15/02

    Combined Hospital Meeting

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    Odontogenic Infections The modern emergency department sees a

    significant number of patients every day

    with problems related to the face and oral

    cavity. Emergency Medicine Clinics of North America Aug 2000

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    35 year old male, 3 day history of

    progressive painful facial swelling,

    difficulty opening mouth, difficulty

    swallowing, alteration in voice. 8 year old female, 5 days s/p dental

    extraction, persistent increasingly painful

    swelling left face, taking augmentin since

    extraction.

    Odontogenic Infections

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    OUTLINEOUTLINE

    MicrobiologyNatural history

    AssessmentManagement

    Prevention

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    Understand important aspects of history and

    clinical examination of patient.

    Understand treatment of odontogenic

    infections and when to refer treatment.

    Odontogenic Infections

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    MICROBIOLOGYMICROBIOLOGY

    Causative organismsAerobes only 7 %

    Anaerobes only 33 %

    Mixed 60 %

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    MICROBIOLOGYMICROBIOLOGY

    Aerobic 25%

    Gram-positive cocci 85%Streptococcus spp. 90%

    Streptococcus (group D) spp. 2%

    Staphylococcus spp. 6%

    Eikenella spp. 2%Gram-negative cocci (Neisseria spp.) 2%

    Gram-positive rods (Corynebacterium spp.) 3%

    Gram-negative rods (Haemophilus spp.) 6%

    Miscellaneous and undifferentiated 4%

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    MICROBIOLOGYMICROBIOLOGY

    Anaerobic 75%

    Gram-positive cocci 30%Streptococcus spp. 33%

    Peptostreptococcus spp. 65%

    Staphylococcus spp. 65%

    Gram-negative cocci (Veillonella spp.) 4%

    Gram-positive rods 14%

    Eubacteriumspp.Lactobacillus spp.

    Actinomyces spp.

    Clostridia spp.

    Gram-negative rods 50%Bacteroides spp. 75%

    Fusobacterium spp. 25%

    Miscellaneous 6%

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    Inoculation

    Cellulitis

    Abscess formation

    Resolution

    NATURAL HISTORY NATURAL HISTORY

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    Predictable spread

    from one anatomic

    space to the next.

    Edema at leading edgeof infection.

    Previously innoculated

    areas progressingthrough stages of

    cellulitis and abscess

    formation

    NATURAL HISTORY NATURAL HISTORY

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    ANATOMIC SPACE INVOLVEMENTANATOMIC SPACE INVOLVEMENT

    Primary maxillary spaces

    CanineBuccal

    Infratemporal

    Primary mandibular spacesSubmental

    Buccal

    Submandibular

    Sublingual

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    ANATOMIC SPACE INVOLVEMENTANATOMIC SPACE INVOLVEMENT

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    ANATOMIC SPACE INVOLVEMENTANATOMIC SPACE INVOLVEMENT

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    ANATOMIC SPACE INVOLVEMENTANATOMIC SPACE INVOLVEMENT

    Secondary fascial spaces

    MassetericPterygomandibular

    Superficial and deep temporal

    Lateral pharyngealRetropharyngeal

    Prevertebral

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    ASSESSMENTASSESSMENT

    Identify cause

    Determine severity

    Evaluate host defenses

    General practitioner / specialist

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    ASSESSMENTASSESSMENT

    Identify cause

    Caries

    Periodontitis

    Pericoronitis

    Tooth tendernessTooth mobility

    Vestibular swelling

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    ASSESSMENTASSESSMENT

    Diagnostic radiographs-Panorex

    -CAT Scan with contrast

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    ASSESSMENTASSESSMENT

    Determine severity

    Complete history

    Chief complaint

    Time of onset

    Change in symptoms

    Elicit symptoms

    Clinical signsDolor, tumor, calor, rubor, and functiolaesa

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    ASSESSMENTASSESSMENT

    Determine severity

    Vital signsLocal involvement

    Extent and rate of

    progressionInvolved spaces

    Trismus

    AirwayVital structures

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    ASSESSMENTASSESSMENT

    Characteristic Cellulitis Abscess

    Duration Acute Chronic

    Pain Severe and generalized Localized

    Size Large Small

    Localization Diffuse borders Well circumscribed

    Palpation Doughy to indurated FluctuantPresence of pus No Yes

    Degree of seriousness Greater Less

    Bacteria Aerobic Anaerobic

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    ASSESSMENTASSESSMENT

    Systemic involvementMalaise

    Pyrexia

    Other signs

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    ASSESSMENTASSESSMENT

    Compromised Host Defenses

    Uncontrolled metabolic diseases

    Uremia

    Alcoholism

    Malnutrition

    Severe diabetes Suppressing diseases

    Leukemia

    Lymphoma

    Malignant tumors

    Suppressing drugs

    Chemotherapeutic agents

    Immunosuppressives

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    ASSESSMENTASSESSMENT

    Criteria for Referral to a Specialist Rapidly progressing infection

    Difficulty breathing

    Difficulty swallowing Fascial space involvement

    Elevated temperature (greater than 101F)

    Severe trismus (less than 10 mm) Toxic appearance

    Compromised host defenses

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    MANAGEMENTMANAGEMENT

    Obtain drainage

    Maintain drainage

    Remove the cause Provide supportive

    care

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    MANAGEMENTMANAGEMENT

    Obtain drainage Pus must be drained

    Adequate access Blunt dissection

    All loculations entered

    Intra - oral and / or

    extra - oral

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    Obtain drainage

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    MANAGEMENTMANAGEMENT

    Maintain drainageAll involved spaces

    Dependent drainage

    Insertion of drain

    Maintenance of

    patency

    Slow advancement

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    MANAGEMENTMANAGEMENT

    Remove the cause

    Pulp extirpation

    Tooth extractionScaling

    Necrotic tissue / debris

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    MANAGEMENTMANAGEMENT

    Provide supportive care

    General

    Fluids

    Rest

    Nutrition

    Warmth

    Antibiotic therapy

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    MANAGEMENTMANAGEMENT

    Principles of antibiotic use

    Necessity

    Empirical therapy

    Narrow spectrum Low toxicity

    Bacteriocidal Administer properly

    Cost

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    MANAGEMENTMANAGEMENT

    Antibiotics Good choices

    Penicillin or amoxicillin ( + / - metronidazole )

    Cephalexin, clindamycin, co-trimoxazole,

    tetracycline, erythromycin

    Poor choicesMetronidazole alone

    Amoxicillin / clavulanic acid

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    PREVENTIONPREVENTION

    Local processes

    Immunocompromised patient General preventive care

    Timely intervention Good surgical technique

    Distant sites

    Infective endocarditis

    Arteriovenous fistulae

    Prosthetic valves and joints