Taxonomic Synonymy Definition Framework CHRONOS & GNS Science New Zealand
No “new risks”, no new laws needed, “product not...
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Christina Ndoh, MPA and Jennifer Kuzma, PhD NC State University, Public Administration Department & Genetics, Engineering and Society Center GET Conference, May 2014
Transcript of No “new risks”, no new laws needed, “product not...
Christina Ndoh, MPA and Jennifer Kuzma, PhD NC State University, Public Administration Department & Genetics, Engineering and Society Center GET Conference, May 2014
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No “new risks”, no new laws needed, “product not process”
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Presenter
Presentation Notes
Taxonomic designation provided for both the donor organism and recipient microorganism Phenotypic information which may include biochemical and physiological traits Genotypic information such as the introduced genetic material and the method used to construct the microorganism Signed statement certifying intent to manufacture R&D activities conducted to date Knowledge of related MO previously reviewed by EPA Major intended application Location and properties for area of environmental release (*TERA only)
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2- Nod factor
production
3- recognition
by host
1- signaling
Image showing symbiosis from: http://www.glycoforum.gr.jp/science/word/saccharide/SA-A02E.html
(M. loti)
(rice crop)
Presenter
Presentation Notes
three possible pathways: 1) inserting the nif cluster directly into the target plant, with the plant’s chloroplast genome serving as the chassis; 2) inserting the cluster into the genetic structure of the plant’s root microbes, or endosymbionts, which live within a plant for at least part of its lifetime; or 3) inserting the gene cluster into soil microbes that surround the plant, such as pseudomonads.
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GEM Application Number of TERAs
Bioluminescent detection of airborne chemicals 5
Enhanced RDX degredation in contaminated groundwater 2
Fecal contamination detection 1
Genetically modified microalgae 5
Land mine detection 6
Napthalene and methyl salicylate detection 1
Nitrogen fixation 6
Pierce's disease in grapes prevention 3
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BJ 5019 (R98-001) JH 359 (R98-002) TN 11912 (R98-003)
Parental Strain USDA 110 JH (USDA 110 selected for a spontaneous Rif-r)
USDA I 11o (a mannitol non-utilizing variant of USDA 110)
Phenotypic information
More nodules on soybean in presence of other strains
Higher symbiotic nitrogen-fixation with or without molybdenum
More nodules and higher nitrogen fixation
Presenter
Presentation Notes
Testing was to begin in April or May of 1998 and continue for 3 years.
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Site Nearest occupied dwelling
Nearest human pop. density (pop.)
Nearest wooded area (major animals)
1 1700 ft. 2.5 mi (500) 1500 ft. (Deer, squirrels, raccoons)
2 800 ft. 1 mi (2000) 2000 ft. (Deer, squirrels, groundhogs)
3 1000 ft. Within city limits (12,000) 1 mi. (Deer, groundhogs)
4 1000 ft. > 5000 ft. (500) 500 ft. (Deer, squirrels, groundhogs)
5 1500 ft. 4 miles (750) 300 ft. (Deer, squirrels, groundhogs)
6 1000 ft. 4.5 miles (3500) 600 ft. (Deer, groundhogs, rabbits)
7 0.5 mi. Morrisonville (500) 0.5 mi. (Deer, squirrels)
8 0.5 mi. Morrisonville (500)
1 mi. (Deer, squirrels)
Site Specific Data (Sites 1-6 in OH, Sites 7&8 in WI)
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Preventative Precautionary Permissive Promotional
Intellectual Property No access to information
Highly restricted access to information
Largely open access to information
Open access to information
Biosecurity Control of information and tools by a few
Several have control of information and tools
Most have control of information and tools
Unrestricted access to information and tools
Biosafety Ban on usage of SB products
Stringent, mandatory government regulation of environmental health and safety
Voluntary or flexible mandatory programs and standards for environmental health and safety
No specific SB provisions or standards for environmental health and safety
Ethics Ban SB application with moral objection
Widespread dialogue and deliberation before SB deployed
Transparent decision-making with input from various non-expert stakeholders
Closed process with little input outside of SB scientific community and decision-makers
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Preventative Precautionary Permissive Promotional
SB Regulation on an Oversight Approach Continuum
(table from Kuzma and Tanji, 2010)
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