Nir Hus Absite Review Q11

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    Absite Topic Review

    General Surgery

    Nir Hus, MD, PhD.Mount Sinai Medical Center

    Miami Beach

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    Transplantation

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    Q1 Two weeks s/p renal transplant, a pt. developes res.Insufficiency requiring adm. To ICU. CXR shows diffuse

    infiltrates & BAL show cells w/ inclusion bodies. The most

    appropriate therapy is:

    A. GangcyclvirB. AcyclovirC. BactrimD. PCN

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    Q2 Hyperacute rejection following organ trans. Is mostoften due:

    A. ABO incompatibilityB. Rh incompatibilityC. Previously sensitized T cellsD. Macrophages

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    Q3 Hyperacute rejection is an example of hypersensitivityreaction type:

    A. Type IB. Type IIC. Type IIID. Type IV

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    Q4 Successful Tx of hyperacute rejection usually involves

    A. SteroidsB. Removal of the organ & re-trans.C. OKT3D. Rapamycin

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    Q5 The machanism of cyclosporin is:

    A. Binds FK binding proteinB. Binds cyclophilin proteinC. Inhibits purine synthesis by way of 6-

    mercaptopurine intermidiate.

    D. Binds antigen on T cells

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    Q6 - The mechanism of azathioprine is:

    A. Binds FK binding proteinB. Binds cyclophilin proteinC. Inhibits purine synthesis by way of 6-

    mercaptopurine intermidiate.

    D. Binds antigen on T cells

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    Q7 The most common malignancy followingtransplantation is:

    A. Lung CAB. Prostate CAC. Breast CAD. Skin CA

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    Q8 A positive cross-match means:

    A. There are no immunologic problems so onemay proceed w/ the trans.

    B. Will likely result in only mild rejectionsometimes after the 1st week.

    C. The recipient has preformed AB to donor Ag.D.

    Both the donor and recipient are CMV positive.

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    Q9 A cross-match is performed by:

    A. Mixing donor lymphocytes w/ recipientserum

    B. Mixing recipient lymphocytes w/ donorserum

    C. Mixing donor plasma w/ recipient serumD. Mixing recipient plasma w/ donor serum.

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    Q10 Post-transplant lymphoproliferative disorder hasbeen most commonly linked to:

    A. HSVB. RSVC. EBVD. Influenza viruses

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    Q11 - A 35 yo man POD#6 from a cadaveric renal trans.Developes a rise in Cr. The most appropriate next step is:

    A. Emergent reopB. AngiographyC. OKT3D. US

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    Q12 in the previous pt. the US shows flow accelerationof the renal artery. The next appropriate step is:

    A. Emergent reopB. AngiographyC. OKT3D. US

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    Q13 in the previous pt. the US is normal. The nextappropriate step is:

    A. Emergent reopB. AngiographyC. OKT3D. Biopsy

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    Q14 - in the previous pt. the Bx. shows acute

    tubulitis. This is consistent w/:

    A. Acute rejectionB. UTIC. Chronic rejectionD. Renal vein thrombosis.

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    Q15 New proteinnuria in a pt. following renal trans. Ismost consistent w/:

    A. Acute rejectionB. UTIC. Chronic rejectionD. Renal vein thrombosis.

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    Q16 Most common cause of acute death in a livingrelated renal trans. Is:

    A. PEB. HemorrhageC. MID. Infection

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    Q17 Most common cause of acute death following renaltrans. In a recipient is:

    A. PEB. HemorrhageC. MID. Infection