Nilai Normal Laboratorium

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Determination Normal Reference Value Conventional units SI units Blood, Plasma or Serum Ammonia (NH3) – diffusion 20-120 mcg/dl 12-70 mcmol/L Ammonia Nitrogen 15-45 µg/dl 11-32 µmol/L Amylase 35-118 IU/L 0.58-1.97 mckat/L Anion gap (Na + -[Cl - + HCO3 - ]) (P) 7-16 mEq/L 7-16 mmol/L Antithrombin III (AT III) 80–120 U/dl 800–1200 U/L Bicarbonate Arterial 21–28 mEq/L 21–28 mmol/L Venous 22–29 mEq/L 22–29 mmol/L Bilirubin Conjugated (direct) Total 0.2 mg/dl & 0.1–1 mg/dl 4 mcmol/L & 2–18 mcmol/L Calcitonin < 100 pg/ml < 100 ng/L Calcium Total 8.6–10.3 mg/dl 2.2–2.74 mmol/L Ionized 4.4–5.1 mg/dl 1–1.3 mmol/L Carbon dioxide content (plasma) 21–32 mmol/L 21–32 mmol/L Carcinoembryonic antigen < 3 ng/ml < 3 mcg/L Chloride 95–110 mEq/L 95–110 mmol/L Coagulation screen Bleeding time 3–9.5 min 180–570 sec Prothrombin time 10–13 sec 10–13 sec Partial thromboplastin time (activated) 22–37 sec 22–37 sec Protein C 0.7–1.4 µ/ml 700–1400 U/ml Protein S 0.7–1.4 µ/ml 700–1400 U/ml Copper, total 70–160 mcg/dl 11–25 mcmol/L

Transcript of Nilai Normal Laboratorium

Page 1: Nilai Normal Laboratorium

Determination Normal Reference Value

Conventional units SI units

Blood, Plasma or Serum

Ammonia (NH3) – diffusion 20-120 mcg/dl 12-70 mcmol/L

Ammonia Nitrogen 15-45 µg/dl 11-32 µmol/L

Amylase 35-118 IU/L 0.58-1.97 mckat/L

Anion gap (Na+-[Cl - + HCO3- ]) (P) 7-16 mEq/L 7-16 mmol/L

Antithrombin III (AT III) 80–120 U/dl 800–1200 U/L

Bicarbonate

Arterial 21–28 mEq/L 21–28 mmol/L

Venous 22–29 mEq/L 22–29 mmol/L

Bilirubin

Conjugated (direct) Total 0.2 mg/dl&0.1–1 mg/dl

4 mcmol/L&2–18 mcmol/L

Calcitonin < 100 pg/ml < 100 ng/L

Calcium

Total 8.6–10.3 mg/dl 2.2–2.74 mmol/L

Ionized 4.4–5.1 mg/dl 1–1.3 mmol/L

Carbon dioxide content (plasma) 21–32 mmol/L 21–32 mmol/L

Carcinoembryonic antigen < 3 ng/ml < 3 mcg/L

Chloride 95–110 mEq/L 95–110 mmol/L

Coagulation screen

Bleeding time 3–9.5 min 180–570 sec

Prothrombin time 10–13 sec 10–13 sec

Partial thromboplastin time (activated) 22–37 sec 22–37 sec

Protein C 0.7–1.4 µ/ml 700–1400 U/ml

Protein S 0.7–1.4 µ/ml 700–1400 U/ml

Copper, total 70–160 mcg/dl 11–25 mcmol/L

Corticotropin (ACTH adrenocorticotropic hormone) – 0800 hr

< 60 pg/ml < 13.2 pmol/L

Cortisol

0800 hr 5–30 mcg/dl 138–810 nmol/L

1800 hr 2–15 mcg/dl 50–410 nmol/L

2000 hr 50% of 0800 hr 50% of 0800 hr

Creatine kinase

Female 20–170 IU/L 0.33–2.83 mckat/L

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Male 30–220 IU/L 0.5–3.67 mckat/L

Creatinine kinase isoenzymes, MB fraction 0–12 IU/L 0–0.2 mckat/L

Creatinine 0.5–1.7 mg/dl 44–150 mcmol/L

Fibrinogen (coagulation factor I) 150–360 mg/dl 1.5–3.6 g/L

Follicle-stimulating hormone (FSH)

Female 2–13 mlU/ml 2–13 IU/L

Midcycle 5–22 mlU/ml 5–22 IU/L

Male 1–8 mlU/ml 1–8 IU/L

Glucose, fasting 65–115 mg/dl 3.6–6.3 mmol/L

Glucose Tolerance Test (Oral)(mg/dl) (mmol/L)

Normal Diabetic Normal DiabeticFasting 70–105 > 140 3.9–5.8 > 7.860 min 120–170 200 6.7–9.4 11.190 min 100–140 200 5.6–7.8 11.1120 min 70–120 140 3.9–6.7 7.8

() – Glutamyltransferase (GGT)

Male 9–50 units/L 9–50 units/L

Female 8–40 units/L 8–40 units/L

Haptoglobin 44–303 mg/dl 0.44–3.03 g/L

Hematologic Tests

Fibrinogen 200–400 mg/dl 2–4 g/L

Hematocrit (Hct)

female 36%-44.6% 0.36–0.446 fraction of 1

male 40.7%-50.3% 0.4–0.503 fraction of 1

Hemoglobin A 1C 5.3%-7.5% of total Hgb

0.053–0.075

Hemoglobin (Hb)

female 12.1–15.3 g/dl 121–153 g/L

male 13.8–17.5 g/dl 138–175 g/L

Leukocyte count (WBC) 3800–9800/mcl 3.8–9.8 x 109/L

Erythrocyte count (RBC)

female 3.5–5 x 106/mcl 3.5–5 x 1012/L

male 4.3–5.9 x 106/mcl 4.3–5.9 x 1012/L

Mean corpuscular volume (MCV) 80–97.6 mcm3 80–97.6 fl

Mean corpuscular hemoglobin (MCH) 27–33 pg/cell 1.66–2.09 fmol/cell

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Mean corpuscular hemoglobin concentrate (MCHC)

33–36 g/dl 20.3–22 mmol/L

Erythrocyte sedimentation rate (sedrate, ESR) 30 mm/hr 30 mm/hr

Erythrocyte enzymes

Glucose-6 – Pphosphate dehydrognase (G-6-PD) 250–5000 units/106 cells

250–5000 mcunits/cell

Determination Reference Value(Conventional units) (SI units)

Blood, Plasma or Serum:

Ammonia (NH3) – diffusion

20–120 mcg/dl 12–70 mcmol/L

Ammonia Nitrogen 15–45 µg/dl 11–32 µmol/LAmylase 35–118 IU/L 0.58–1.97 mckat/LAnion gap (Na+-[Cl - + HCO3

-]) (P) 7–16 mEq/L 7–16 mmol/LAntithrombin III (AT III) 80–120 U/dl 800–1200 U/LBicarbonate: Arterial

Venous21–28 mEq/L22–29 mEq/L

21–28 mmol/L

22–29 mmol/LBilirubin: Conjugated (direct) Total 0.2 mg/dl

(0.1–1 mg/dl) 4 mcmol/L(2–18 mcmol/L)

Calcitonin < 100 pg/ml < 100 ng/LCalcium: Total

Ionized8.6–10.3 mg/dl

4.4–5.1 mg/dl

2.2–2.74 mmol/L

1–1.3 mmol/LCarbon dioxide content (plasma) 21–32 mmol/L 21–32 mmol/LCarcinoembryonic antigen < 3 ng/ml < 3 mcg/LChloride 95–110 mEq/L 95–110 mmol/LCoagulation screen:

Bleeding timeProthrombin time

Partial thromboplastin time (activated)

Protein C

Protein S

3–9.5 min

10–13 sec

22–37 sec

0.7–1.4 µ/ml

0.7–1.4 µ/ml

180–570 sec

10–13 sec

22–37 sec

700–1400 U/ml

700–1400 U/ml

Copper, total 70–160 mcg/dl 11–25 mcmol/LCorticotropin(ACTH adrenocorticotropic hormone) – 0800 hr

< 60 pg/ml < 13.2 pmol/L

Cortisol: 0800 hr1800 hr2000 hr

5–30 mcg/dl2–15 mcg/dl

50% of 0800 hr

138–810 nmol/L

50–410 nmol/L

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50% of 0800 hrCreatine kinase: Female

Male20–170 IU/L

30–220 IU/L

0.33–2.83 mckat/L0.5–3.67 mckat/L

Creatinine kinase isoenzymes, MB fraction 0–12 IU/L 0–0.2 mckat/LCreatinine 0.5–1.7 mg/dl 44–150 mcmol/LFibrinogen (coagulation factor I) 150–360 mg/dl 1.5–3.6 g/LFollicle-stimulating hormone (FSH):

Female

Midcycle

Male

2–13 mlU/ml

5–22 mlU/ml1–8 mlU/ml

2–13 IU/L

5–22 IU/L

1–8 IU/L

Glucose, fasting 65–115 mg/dl 3.6–6.3 mmol/LGlucose Tolerance Test (Oral)

Fasting

60 min90 min

120 min

(mg/dl)Normal Diabetic70–105 > 140120–170 200100–140 20070–120 140

(mmol/L)Normal Diabetic3.9–5.8 > 7.86.7–9.4 11.15.6–7.8 11.13.9–6.7 7.8

() -Glutamyltransferase (GGT):

Male

Female

9–50 units/L8–40 units/L

9–50 units/L

8–40 units/L

Haptoglobin 44–303 mg/dl 0.44–3.03 g/L

DeterminationReference Value

Conventional units SI unitsHematologic tests:

Fibrinogen

Hematocrit (Hct),female

male

Hemoglobin A 1C

Hemoglobin (Hb),female

200–400 mg/dl

36%-44.6%

40.7%-50.3%

5.3%-7.5% of total Hgb

12.1–15.3 g/dl

13.8–17.5 g/dl

3800–9800/mcl

2–4 g/L

0.36–0.446 fraction of 1

0.4–0.503 fraction of 1

0.053–0.075

121–153 g/L

138–175 g/L

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male

Leukocyte count (WBC)Erythrocyte count (RBC):female

male

Mean corpuscular volume (MCV)

Mean corpuscular hemoglobin(MCH)

Mean corpuscular hemoglobin

concentrate (MCHC)

Erythrocyte sedimentation rate

(sedrate, ESR)

3.5–5 x 106/mcl

4.3–5.9 x 106/mcl

80–97.6 mcm3

27–33 pg/cell

33–36 g/dl

30 mm/hr

3.8–9.8 x 109/L

3.5–5 x 1012/L

4.3–5.9 x 1012/L

80–97.6 fl

1.66–2.09 fmol/cell

20.3–22 mmol/L

30 mm/hr

Erythrocyte enzymes:

Glucose-6 -Pphosphate dehydrognase

(G-6-PD)

Ferritin

Folic acid: normal

Platelet count

Reticulocytes

Vitamin B12

250–5000 units/106 cells

10–383 ng/ml

>3.1–12.4 ng/ml

150–450 x 103/mcl

0.5%-1.5% of erythrocytes

223–1132 pg/ml

250–5000 mcunits/cell

23–862 pmol/L

7–28.1 nmol/L

150–450 x 109/L

0.005–0.015

165–835 pmol/L

Iron: FemaleMale

30–160 mcg/dl

45–160 mcg/dl

5.4–31.3 mcmol/L

8.1–31.3 mcmol/LIron binding capacity 220–420 mcg/dl 39.4–75.2 mcmol/LIsocitrate dehydrogenase 1.2–7 units/L 1.2–7 units/LIsoenzymes

Fraction 1

14%-26% of total

29%-39% of total

0.14–0.26 fraction of total

0.29–0.39 fraction of

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Fraction 2

Fraction 3

Fraction 4

Fraction 5

20%-26% of total

8%-16% of total

6%-16% of total

total0.20–0.26 fraction of total

0.08–0.16 fraction of total

0.06–0.16 fraction of total

Lactate dehydrogenase 100–250 IU/L 1.67–4.17 mckat/LLactic acid (lactate) 6–19 mg/dl 0.7–2.1 mmol/LLead 50 mcg/dl 2.41 mcmol/LLipase 10–150 units/L 10–150 units/LLipids:

Total Cholesterol

Desirable

Borderline-high

High

LDL

Desirable

Borderline-high

High

HDL (low)

Triglycerides

Desirable

Borderline-high

High

Very high

< 200 mg/dl

200–239 mg/dl

> 239 mg/dl

< 130 mg/dl

130–159 mg/dl

> 159 mg/dl

< 35 mg/dl

< 200 mg/dl

200–400 mg/dl

400–1000 mg/dl

> 1000 mg/dl

< 5.2 mmol/L

< 5.2–6.2 mmol/L

> 6.2 mmol/L

< 3.36 mmol/L

3.36–4.11 mmol/L

> 4.11 mmol/L

< 0.91 mmol/L

< 2.26 mmol/L

2.26–4.52 mmol/L

4.52–11.3 mmol/L

> 11.3 mmol/L

Magnesium 1.3–2.2 mEq/L 0.65–1.1 mmol/LOsmolality 280–300 mOsm/kg 280–300 mmol/kgOxygen saturation (arterial) 94%-100% 0.94 – fraction of 1

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PCO2, arterial 35–45 mm Hg 4.7–6 kPapH, arterial 7.35–7.45 7.35–7.45

DeterminationReference Value

Conventional units SI unitsPO, arterial: Breathing room air

On 100% O

80–105 mm Hg

> 500 mm Hg

10.6–14 kPa

Phosphatase (acid), total at 37°C 0.13–0.63 IU/L 2.2–10.5 IU/L or

2.2–10.5 mckat/LPhosphatase alkaline 20–130 IU/L 20–130 IU/L or

0.33–2.17 mckat/LPhosphorus, inorganic, (phosphate) 2.5–5 mg/dl 0.8–1.6 mmol/LPotassium 3.5–5 mEq/L 3.5–5 mmol/LProgesterone

Female

Follicular phase

Luteal phase

Male

0.1–1.5 ng/ml

0.1–1.5 ng/ml2.5–28 ng/ml

< 0.5 ng/ml

0.32–4.8 nmol/L

0.32–4.8 nmol/L

8–89 nmol/L

< 1.6 nmol/L

Prolactin 1.4–24.2 ng/ml 1.4–24.2 mcg/LProstate specific antigen

Protein: TotalAlbumin

Globulin

0–4 ng/ml

6–8 g/dl

3.6–5 g/dl

2.3–3.5 g/dl

0–4 ng/ml60–80 g/L

36–50 g/L

23–35 g/L

Rheumatoid factor < 60 IU/ml < 60 kIU/LSodium 135–147 mEq/L 135–147 mmol/LTestosterone:Female

Male

6–86 ng/dl

270–1070 ng/dl

0.21–3 nmol/L

9.3–37 nmol/L

Thyroid Hormone Function Tests:

Thyroid-stimulating hormone (TSH)

Thyroxine-binding globulin capacity

0.35–6.2 mcU/ml

10–26 mcg/dl

75–220 ng/dl

4–11 mcg/dl

0.35–6.2 mU/L

100–260 mcg/L

1.2–3.4 nmol/L

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Total triiodothyronine (T3)

Total thyroxine by RIA (T4)T3 resin uptake

25%-38% 51–142 nmol/L

0.25–0.38 fraction of 1

Transaminase, AST (aspartate aminotransferase, SGOT)

11–47 IU/L 0.18–0.78 mckat/L

Transaminase, ALT (alanine aminotransferase, SGPT)

7–53 IU/L 0.12–0.88 mckat/L

Transferrin 220–400 mg/dL 2.20–4.00 g/LUrea nitrogen (BUN) 8–25 mg/dl 2.9–8.9 mmol/LUric acid 3–8 mg/dl 179–476 mcmol/LVitamin A (retinol) 15–60 mcg/dl 0.52–2.09 mcmol/LZinc 50–150 mcg/dl 7.7–23 mcmol/L

1 Tergantung pada usia

2 Bayi dan anak sampai 104 U/L

3 Bayi usia 1 tahun sampai 6 mg/dl

Urine

DeterminationReference Value

Conventional units SI unitsCalcium 50–250 mcg/day 1.25–6.25 mmol/dayCatecholamines:

Epinephrine

Norepinephrine

< 20 mcg/day

< 100 mcg/day

< 109 nmol/day

< 590 nmol/day

Catecholamines, 24-hr < 110 µg < 650 nmolCopper 15–60 mcg/day 0.24–0.95 mcmol/dayCreatinine:

Child

Adolescent

FemaleMale

8–22 mg/kg

8–30 mg/kg

0.6–1.5 g/day

0.8–1.8 g/day

71–195 µmol/kg71–265 µmol/kg

5.3–13.3 mmol/day

7.1–15.9 mmol/day

pH 4.5–8 4.5–8Phosphate 0.9–1.3 g/day 29–42 mmol/dayPotassium 25–100 mEq/day 25–100 mmol/day

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Protein

Total

At rest

1–14 mg/dL

50–80 mg/day

10–140 mg/L

50–80 mg/day

Protein, quantitative < 150 mg/day < 0.15 g/daySodium 100–250 mEq/day 100–250 mmol/daySpecific gravity, random 1.002–1.030 1.002–1.030Uric acid, 24-hr 250–750 mg 1.48–4.43 mmol

1 Tergantung pada diet.

Drug Levels*

Drug DeterminationReference Value

Conventional units SI units

Aminoglycosides

Amikacin

(trough)

(peak)

1–8 mcg/ml

1.7–13.7 mcmol/L20–30 mcg/ml34–51 mcmol/L

Gentamicin

(trough)

(peak)

0.5–2 mcg/ml

6–10 mcg/ml

1–4.2 mcmol/L

12.5–20.9 mcmol/LKanamycin

(trough)

(peak)5–10 mcg/ml20–25 mcg/ml

nd

ndNetilimicin

(trough)

(peak)0.5–2 mcg/ml6–10 mcg/ml

nd

ndStreptomycin

(trough)

(peak)< 5 mcg/ml5–20 mcg/ml

nd

ndTobramycin

(trough)

(peak)0.5–2 mcg/ml5–20 mcg/ml

1.1–4.3 mcmol/L

12.8–21.8 mcmol/LDrug Determination Reference Value

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Conventional units SI units

Antiarrhythmics

Amiodarone 0.5–2.5 mcg/ml 1.5–4 mcmol/LBretylium 0.5–1.5 mcg/ml ndDigitoxin 9–25 mcg/L 11.8–32.8 nmol/LDigoxin 0.8–2 ng/ml 0.9–2.5 nmol/LDisopyramide 2–8 mcg/ml 6–18 mcmol/LFlecainide 0.2–1 mcg/ml ndLidocaine 1.5–6 mcg/ml 4.5–21.5 mcmol/LMexiletine 0.5–2 mcg/ml ndProcainamide 4–8 mcg/ml 17–34 mcmol/mlPropranolol 50–200 ng/ml 190–770 nmol/LQuinidine 2–6 mcg/ml 4.6–9.2 mcmol/LTocainide 4–10 mcg/ml ndVerapamil 0.08–0.3 mcg/ml nd

Anticonvulsants

Carbamazepine 4–12 mcg/ml 17–51 mcmol/LPhenobarbital 10–40 mcg/ml 43–172 mcmol/LPhenytoin 10–20 mcg/ml 40–80 mcmol/LPrimidone 4–12 mcg/ml 18–55 mcmol/LValproic Acid 40–100 mcg/ml 280–700 mcmol/L

Antidepressants

Amitriptyline 110–250 ng/ml 500–900 nmol/LAmoxapine 200–500 ng/ml ndBupropion 25–100 ng/ml ndClomipramine 80–100 ng/ml ndDesipramine 115–300 ng/ml ndDoxepin 110–250 ng/ml ndImipramine 225–350 ng/ml ndMaprotiline 200–300 ng/ml ndNortriptyline 50–150 ng/ml ndProtriptyline 70–250 ng/ml ndTrazodone 800–1600 ng/ml nd

Antipsychotics

Chlorpromazine 50–300 ng/ml 150–950 nmol/LFluphenazine 0.13–2.8 ng/ml ndHaloperidol 5–20 ng/ml ndPerphenazine 0.8–1.2 ng/ml ndThiothixene 2–57 ng/ml nd

Drug DeterminationReference Value

Conventional units SI unitsMiscellaneous Amantadine

Amrinone

300 ng/ml

3.7 mcg/ml

nd

ndChloramphenicol 10–20 mcg/ml 31–62 mcmol/LCyclosporine 250–800 ng/ml

(whole blood, RIA)

nd

nd

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50–300 ng/ml (plasma, RIA)Ethanol 0 mg/dl 0 mmol/LHydralazine 100 ng/ml ndLithium 0.6–1.2 mEq/L 0.6–1.2 mmol/LSalicylate 100–300 mg/L 724–2172 mcmol/LSulfonamide 5–15 mg/dl ndTerbutaline 0.5–4.1 ng/ml ndTheophylline 10–20 mcg/ml 55–110 mcmol/LVancomycin

(trough)

(peak)5–15 ng/ml20–40 mcg/ml

nd

nd

* Nilai yang diberikan secara umum dapat digunakan untuk terapi tanpa terjadi efek toksik pada kebanyakan pasien, Namun pengecualian juga tidak jarang terjadi.

1 nd = data tidak tersedia.

2 Metabolit N-desmethyl beserta turunannya.

3 Nilai 24 jam.

4 Toksik: 50–100 mg/dl (10.9–21.7 mmol/L).

Diambil dari The Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, National Institutes of Health.

Classification of Blood Pressure *

CategoryReference value

Systolic (mm Hg) Diastolic (mm Hg)Optimal < 120 and < 80Normal < 130 and < 85High-normal 130–139 or 85–89Hypertension

Stage 1

Stage 2

Stage 3

140–159160–179

180

or

or

or

90–99100–109

110

* Untuk dewasa berusia 18 atau lebih yang tidak dalam pengobatan anti hipertensi dan tidak dalam kondisi akut. Ketika tekanan sistole dan diastole masuk ke dalam kategori lain, maka

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kategori di atasnya harus dipilih untuk menentukan klasifikasi status tekanan darah penderita. Sebagai tambahan dalam menentukan stadium hipertensi, seorang praktisi medis harus menentukan ada atau tidaknya penyakit pada target organ serta faktor resiko lainnya.

1 Tekanan darah yang optimal terhadap resiko kardiovaskular adalah dibawah 120/88 m Hg. Namun demikian, nilai rendah yang tidak wajar harus dievaluasi untuk menemukan kelainan klinis yang signifikan.

2 Berdasarkan atas pembacaan sebanyak 2 kali atau lebih pada pemeriksaan awal.