NIH Small Grants Linda Rueckert
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Transcript of NIH Small Grants Linda Rueckert
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NIH Small Grants
Linda RueckertNEIU Office of Research Development
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This PowerPoint can be found at:
http://www.neiu.edu/~ordev
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• Academic Research Enhancement Award (AREA; R15)
• Small grants (R03)
• NIH – Academic-Community Partnership Conference Series
• General information about NIH
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Office of the DirectorOffice of the Director
National Instituteon Alcohol Abuseand Alcoholism
National Instituteon Alcohol Abuseand Alcoholism
National Instituteof Arthritis andMusculoskeletal
and Skin Diseases
National Instituteof Arthritis andMusculoskeletal
and Skin Diseases
National CancerInstitute
National CancerInstitute
National Instituteof Diabetes andDigestive and
Kidney Diseases
National Instituteof Diabetes andDigestive and
Kidney Diseases
National Instituteof Dental andCraniofacial
Research
National Instituteof Dental andCraniofacial
Research
National Instituteon Drug Abuse
National Instituteon Drug Abuse
National Instituteof Environmental Health Sciences
National Instituteof Environmental Health Sciences
National Instituteon Aging
National Instituteon Aging
National Instituteof Child Health
and HumanDevelopment
National Instituteof Child Health
and HumanDevelopment
National Institute onDeafness and Other
CommunicationDisorders
National Institute onDeafness and Other
CommunicationDisorders
National EyeInstitute
National EyeInstitute
National HumanGenome Research
Institute
National HumanGenome Research
Institute
National Heart,Lung, and Blood
Institute
National Heart,Lung, and Blood
Institute
National Instituteof Mental Health
National Instituteof Mental Health
National Instituteof NeurologicalDisorders and
Stroke
National Instituteof NeurologicalDisorders and
Stroke
National Instituteof General
Medical Sciences
National Instituteof General
Medical Sciences
National Instituteof Nursing Research
National Instituteof Nursing Research
National Libraryof Medicine
National Libraryof Medicine
Center forScientific
Review
Center forScientific
Review
Center forInformationTechnology
Center forInformationTechnology
National Centerfor Complementary
and AlternativeMedicine
National Centerfor Complementary
and AlternativeMedicine
National Instituteof Allergy and
Infectious Diseases
National Instituteof Allergy and
Infectious Diseases
FogartyInternational
Center
FogartyInternational
Center
National Centerfor ResearchResources
National Centerfor ResearchResources
National Institutes of HealthNational Institutes of Health
Clinical Center
Clinical Center
National Center on Minority Health andHealth Disparities
National Center on Minority Health andHealth Disparities
National Institute of Biomedical Imagingand Bioengineering
National Institute of Biomedical Imagingand Bioengineering
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Academic Research Enhancement Award (AREA)
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• Stimulate research at smaller schools that are not major recipients of NIH funding
• Support meritorious scientific research in the biomedical and behavioral sciences
• Expose students to meritorious research
Objectives of the AREA Program
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• Up to $150,000 direct costs, plus applicable facilities and administrative (F&A) costs, expressed in modules of $25,000
• Up to 36 months of support awarded in a single budget/project period.
• Majority of research must be done at the eligible, applicant organization.
• Eligible for administrative supplements for under-represented minority students
Details: http://grants.nih.gov/grants/guide/pa-files/PA-06-042.html
Features of the AREA Program
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Allocation Examples of $150,000 (in $25,000 modules)
Budget Period
First Year Second Year
Third Year
3-YearAward
$50,000 $50,000 $50,000
2-YearAward
$75,000 $75,000
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Eligibility of College/University/School
• Domestic educational institution (public or private)
• Institution granting baccalaureate or higher level degree in a health-related science, such as biology, chemistry, microbiology, bioengineering, bioinformatics, computational biology, etc.
• In 4 or more of the last 7 years, no more than $3 Million in Total Costs (DC + F&A Costs) per year in NIH research support.
• Eligible at time of application and at time of award
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Eligibility of College/University/School
• Eligibility based on entire College/University or on individual health-related Colleges with the University.
• Eligibility “formula” is two-tiered. Based on award data for last 7 fiscal years. Only determines ineligibility.
• Breaks out the following Colleges within a University: School/College of Medicine, Veterinary Medicine, Podiatry, Nutrition, Dentistry, Osteopathy, Pharmacy, Public Health, Optometry, Nursing, Chiropractic Medicine, and Allied Health. All NIH funding considered “Other Academic.”
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Eligibility of the Principal Investigator
• Tied to eligibility of applicant organization• No application for the same project as a
pending AREA application in the same cycle• Eligible for only one AREA grant at a time• Must be registered in ERA Commons• Transfer of PI may cause ineligibility• Publications a plus but not required; expertise
may be demonstrated by preliminary data
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Submitting an Application
• Electronic submission only • Modular format; use modular budget forms• Appendices permitted but limited• Three Receipt dates per year: February 25,
June 25, and October 25 (also AIDS-specific receipt dates)
• Due electronically by 5:00 p.m. local time.• New, Renewal, and Resubmissions permitted• 25 pages allowed for research plan• R15 applications are for research, not
training
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AREA or R15 Application Timeline
Cycle I Cycle II Cycle III
Submissions Feb 25 June 25 Oct 25
Review Jun/Jul Oct/Nov Feb/Mar
Council Sept/Oct Jan/Feb May/Jun
Award Dec/Jan April /MayJuly/Aug
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Review Criteria and Considerations
Standard NIH review criteria: significance, approach, innovation, investigator, environment.
Reviewers to comment in the Overall Evaluation on whether the application addresses the goals of the AREA program
Priority scores only; not percentiled
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AREA Application & Award Data1999-2005
Year
# Competin
g
# Awards
Success Rate
$ Awarded ($1,000s)
1999 441 180 39.5 17,634
2000 501 125 25.0 19,871
2001 523 164 33.8 23,901
2002 500 188 38.8 26,277
2003 506 214 42.3 30,467
2004 619 195 31.2 37,633
2005 662 197 29.8 39,740
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Small Research Grants (R03)
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Small Research Grants (R03)• Up to $50K per year for 2
Years (plus F&A)
• Some institutes may have different restrictions (e.g. new investigators only)
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Small Research Grants (R03) cont’d• Electronic submission
through grants.gov• Receipt dates: Feb. 16,
June 16, Oct. 16• Research plan may not
exceed 10 pages• Preliminary data not
required
More info: http://grants.nih.gov/grants/guide/pa-files/PA-06-180.html
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Academic-Community Partnership Conference Series
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Academic-Community Partnership Conference Series• Limited to EARDA institutions.
• Conduct health-disparities related workshops and meetings.
• Topics: violence reduction, obesity, health literacy, information dissemination, infant mortality, fibroid tumors.
• Academics and community members meet to develop a research agenda.
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Academic-Community Partnership Conference Series cont’d
• Up to $30,000 per year.
• Up to 3 years.
• Develop a proposal for a larger grant to carry out the research.
• Letter of intent receipt date: May 17
• Application receipt date: June 17
More info: http://grants.nih.gov/grants/guide/pa-files/PAR-08-106.html
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NIH – General Information• Types of Funding
Opportunity Announcements
• Organization of NIH• Application Process• Proposal writing tips
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National Institutes of Health FOAs
• “Parent” FOAs• Program Announcements (PAs)• Requests for Application (RFAs)• All posted in the NIH Guide for Grants and
Contracts (http://grants2.nih.gov/grants/guide/)
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NIH Parent FOAs
• Generic• Can be on any health-related
topic• Ongoing receipt dates• Examples: R03 (small grants);
R15; R01
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Program Announcement (PA)
• More specific than parents• Same receipt dates• Same review process• “Fit” to PA not part of review• No funds set aside• Can revise and resubmit
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NIH Request for Applications
• More specific• Funds set aside• Success rate depends on
number of appls• Separate review with specific
criteria• One time only - no
resubmission• May have different receipt date
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NIH Organization
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The NIH Extramural Team
ProgramStaff
ReviewStaff
GrantsManagement
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Office of the DirectorOffice of the Director
National Instituteon Alcohol Abuseand Alcoholism
National Instituteon Alcohol Abuseand Alcoholism
National Instituteof Arthritis andMusculoskeletal
and Skin Diseases
National Instituteof Arthritis andMusculoskeletal
and Skin Diseases
National CancerInstitute
National CancerInstitute
National Instituteof Diabetes andDigestive and
Kidney Diseases
National Instituteof Diabetes andDigestive and
Kidney Diseases
National Instituteof Dental andCraniofacial
Research
National Instituteof Dental andCraniofacial
Research
National Instituteon Drug Abuse
National Instituteon Drug Abuse
National Instituteof Environmental Health Sciences
National Instituteof Environmental Health Sciences
National Instituteon Aging
National Instituteon Aging
National Instituteof Child Health
and HumanDevelopment
National Instituteof Child Health
and HumanDevelopment
National Institute onDeafness and Other
CommunicationDisorders
National Institute onDeafness and Other
CommunicationDisorders
National EyeInstitute
National EyeInstitute
National HumanGenome Research
Institute
National HumanGenome Research
Institute
National Heart,Lung, and Blood
Institute
National Heart,Lung, and Blood
Institute
National Instituteof Mental Health
National Instituteof Mental Health
National Instituteof NeurologicalDisorders and
Stroke
National Instituteof NeurologicalDisorders and
Stroke
National Instituteof General
Medical Sciences
National Instituteof General
Medical Sciences
National Instituteof Nursing Research
National Instituteof Nursing Research
National Libraryof Medicine
National Libraryof Medicine
Center forScientific
Review
Center forScientific
Review
Center forInformationTechnology
Center forInformationTechnology
National Centerfor Complementary
and AlternativeMedicine
National Centerfor Complementary
and AlternativeMedicine
National Instituteof Allergy and
Infectious Diseases
National Instituteof Allergy and
Infectious Diseases
FogartyInternational
Center
FogartyInternational
Center
National Centerfor ResearchResources
National Centerfor ResearchResources
National Institutes of HealthNational Institutes of Health
Clinical Center
Clinical Center
National Center on Minority Health andHealth Disparities
National Center on Minority Health andHealth Disparities
National Institute of Biomedical Imagingand Bioengineering
National Institute of Biomedical Imagingand Bioengineering
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NIH Institutes and Centers (ICs) with ExtramuralFunding Authority
• National Cancer Institute (NCI)• National Eye Institute (NEI)• National Heart, Lung, and Blood Institute (
NHLBI)• National Human Genome Research
Institute (NHGRI)• National Institute on Aging (NIA)• National Institute on Alcohol Abuse and
Alcoholism (NIAAA)• National Institute of Allergy and Infectious
Diseases (NIAID)• National Institute of Arthritis and
Musculoskeletal and Skin Diseases (NIAMS)
• National Institute of Biomedical Imaging and Bioengineering (NIBIB)
• National Institute of Child Health and Human Development (NICHD)
• National Institute on Deafness and Other Communication Disorders (NIDCD)
• National Institute of Dental and Craniofacial Research (NIDCR)
• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• National Institute on Drug Abuse (NIDA)• National Institute of Environmental
Health Sciences (NIEHS)• National Institute of General Medical
Sciences (NIGMS)• National Institute of Mental Health
(NIMH)• National Institute of Neurological
Disorders and Stroke (NINDS)• National Institute of Nursing Research
(NINR)• National Library of Medicine (NLM)• Fogarty International Center (FIC)• National Center for Complementary and
Alternative Medicine (NCCAM)• National Center on Minority Health and
Health Disparities (NCMHD)• National Center for Research Resources
(NCRR)
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NICHD Organizational Chart• Center for Developmental Biology and
Perinatal Medicine (CDBPM)• Center for Population Research
(CPR)• National Center for Medical
Rehabilitation Research (NCMRR) • Center for Research for Mothers
and Children (CRMC)
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Center for Research for Mothers and Children (CRMC)
• The Center for Research for Mothers and Children (CRMC), serves as the principal NIH source of support for research and research training in maternal and child health. CRMC-supported scientists are advancing fundamental and clinical knowledge concerning maternal health and child development problems such as low birth weight, mental retardation and developmental disabilities, specific learning disabilities, congenital and genetic defects, growth retardation, HIV, and other congenital infections and diseases. The major goals of the Center are to ensure that mothers and families are healthy, and that all babies are born healthy and will reach adulthood and achieve their full potential.
• Endocrinology, Nutrition and Growth Branch (ENG)
• Child Development and Behavior Branch (CDB)
• Pediatric, Adolescent and Maternal AIDS Branch (PAMA)
• Obstetric and Pediatric Pharmacology Branch (OPP)
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NIH Application Process
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• Identify research question with clear aims and hypotheses
• Identify potential collaborators
• Contact program staff from NICHD
• Send brief concept paper identifying significance, aims, hypotheses, methods, sample, analysis, and impact
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Program Officials’ role in Application Development
• Develop concepts for Institute/Center Initiatives
• Communicate goals of Institute/Center Initiatives
• Advise applicants on funding mechanisms • Provide grant writing advice and study
section information • Advises on application procedures,
requirements and general grant policy
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Over 80,000 applications are received each year by CSR, which checks for compliance with NIH policies and then makes 2 assignments:• Program assignment to Institute/Center (IC) for
possible funding consideration• Review assignment to a Scientific Review Group
(SRG)
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Referral for Review
• Assignments are made to CSR Study Section or to an Institute/Center Review Group – Topics addressed in the
application– Areas of expertise in the Study
Section– Certain kinds of applications
always go to an Institute/Center for review
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Review Criteria
• Significance• Approach• Innovation• Investigators• Environment
Plus HS Protection & Inclusion of Gender,
Minority and Children
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Grant Application Cycle
National Institutes of HealthNational Institutes of Health
Center for Scientific Review(Receipt & Referral)
Center for Scientific Review(Receipt & Referral)
Scientific Review GroupScientific Review Group
Institute/CenterInstitute/Center
Advisory Councils and BoardsAdvisory Councils and Boards
Institute DirectorInstitute Director
ApplicantInstitution
ApplicantInstitution
PrincipalInvestigator
PrincipalInvestigator
Submits Application
Receives AwardMakes Assurances Allocates Funds
Initiates Research Idea
Conducts Research
Makes Funding Decision
Performs Second-Level Review
Evaluates for Program Relevance
Reviews for Scientific Merit
Accepts & Assigns to IC & SRG
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Timeline: New Applications
ReceiptDate
February 1
June 1
October 1
ScientificReview
July
October
March
CouncilReview
October
February
June
AwardDate
December
April
July
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• Carefully read instructions before starting• Know and refer to the literature of your area• State strong rationale of proposed
investigation• Include well-designed tables and figures• Present an organized, lucid write-up• Obtain pre-review from faculty at your
institution• Never assume reviewers “will know what you
mean.”
Proposal Writing Tips
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Grantsmanship
• Remember, reviewers have a day job• Project a realistic amount of work• Be sure you have found key references• Know your reviewers/peers• Minimize typographical errors
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Concerns Raised by Reviewers
• Lack of new or original ideas• Absence of an acceptable scientific rationale,
uncritical approach• Lack of experience in the essential methodology• Questionable reasoning in experimental
approach• Diffuse, superficial, or unfocused research plan,
insufficient experimental detail• Lack of knowledge of published relevant work• Unrealistic amount of work• Uncertainty concerning future directions