Nicola L. B. Pohl Joan and Marvin Carmack Chair of ... · NICOLA POHL • AUGUST 6, 2018 • PAGE 2...

Nicola L. B. Pohl Joan and Marvin Carmack Chair of Bioorganic Chemistry, Indiana University Department of Chemistry 120A Simon Hall, 212 S. Hawthorne Drive, Bloomington, IN 47405 USA Telephone: 812-855-0298 [email protected] Research group web page: http://www.indiana.edu/~pohllab/index.html I. EDUCATION Stanford University, October 1997-July 2000. National Institute of General Medical

Sciences Postdoctoral Fellow, Department of Chemical Engineering, Stanford, CA. Advisor: Prof. Chaitan Khosla.

University of Wisconsin-Madison, August 1991-September 1997. Ph.D. granted in December 1997. Department of Chemistry, Madison, WI. Thesis advisor: Prof. Laura L. Kiessling. Thesis title: Synthesis of Carbohydrate-Based Ligands for the Selectins and Galectins.

Harvard-Radcliffe College, September 1987-June 1991. A.B. (cum laude) granted in June

1991 in English and American Literature and Languages with the Comparative Study of Religions, Cambridge, MA. Thesis title: Disease as a Metaphor for Sin and Guilt in the Works of Flannery O’Connor and Walker Percy.

II. PROFESSIONAL POSITIONS

Joan and Marvin Carmack Chair of Bioorganic Chemistry and Co-director of the Graduate Training Program in Quantitative and Chemical Biology (QCB), Indiana University Department of Chemistry, Bloomington, IN, July 2012-present. Visiting Professor, Massachusetts Institute of Technology, Cambridge, MA, Sabbatical/research leave, October 2017-May 2018. Radcliffe Institute Fellow, Radcliffe Institute for Advanced Study at Harvard University, Cambridge, MA, Sabbatical/research leave, September 2017-May 2018.

Collaborator, Iowa State University Department of Chemistry, Department of Chemical and Biological Engineering, and the Plant Sciences Institute, Ames, IA, July 2012-present. Professor with tenure and the Wilkinson Professor of Interdisciplinary Engineering, Iowa State University Department of Chemistry, Department of Chemical and Biological Engineering, and the Plant Sciences Institute, Ames, IA, January 2011-June 2012. Professor with tenure and Caldwell Chair of Chemistry, Iowa State University Department of Chemistry and the Plant Sciences Institute, Ames, IA, June 2009-2010.

NICOLA POHL • AUGUST 6, 2018 • PAGE 2

Faculty in the Interdepartmental Graduate Program in Microbiology, Iowa State University, Ames, IA, January 2009-July 2012. Associate Professor with tenure and Caldwell Chair of Chemistry, Iowa State University Department of Chemistry and the Plant Sciences Institute, Ames, IA, June 2006-May 2009. Assistant Professor, Iowa State University Department of Chemistry and the Plant Sciences Institute, Ames, IA, August 2000-May 2006. Visiting Professor, University of Zurich Institute of Organic Chemistry, Department of Chemistry, Zurich (Switzerland), May-June 2005.

Graduate Research Assistant, University of Wisconsin-Madison Department of Chemistry, Madison, WI, October 1991-September 1997.

Teaching Assistant, Organic Lab Course and First Semester Organic Chemistry, University of

Wisconsin-Madison Department of Chemistry, Madison, WI, August 1991-May 1992. Supervisor: Dr. Paul Schatz.

Undergraduate Research Assistant, Harvard University Department of Chemistry, Cambridge, MA, December 1989-June 1991. Research Advisor: Joseph J. Grabowski.

III. AWARDS, HONORS, OFF-CAMPUS LEADERSHIP POSITIONS, AND

EDITORIAL/ADVISORY BOARD MEMBERSHIPS

Melville L. Wolfram Award, Division of Carbohydrate Chemistry, American Chemical Society, 2018.

Harry and Carol Mosher Award, Silicon Valley American Chemical Society, 2017. Study section member for the US National Institutes of Health, National Institutes of

General Medical Sciences Training and Workforce Development Subcommittee B (TWD-B), 2017-2019.

Edward, Frances, and Shirley B. Daniels Fellow of the Radcliffe Institute for Advanced Study at Harvard University (Cambridge, MA), 2017-2018.

International Fluorous Technology Award, 2017. Guest Editor, special issue on Carbohydrates, Chemical Reviews, 2016-present. Pfizer-MIT Lecture, 2016. Co-Chair, Telluride Science Research Center Meeting on Enabling Technologies for

Reactions and Processes, 2015, 2017. Synthesis Group Leader, US National Institutes of Health Common Fund Glycosciences

Program, 2015-present. Editorial Advisory Board, Organic Letters (American Chemical Society), 2015-2021. Editorial Advisory Board, The Journal of Organic Chemistry (American Chemical Society),

2014-2020. Joan and Marvin Carmack Chair in Bioorganic Chemistry, 2012-present. Elected as Chair-Elect/Chair/Past-Chair for the Division of Carbohydrate Chemistry,

American Chemical Society, 2012-2014.


Wilkinson Professor of Interdisciplinary Engineering, 2011-2012. Scientific Advisory Board, Research Corporation for Science Advancement (Tucson, AZ), 2011-2017

Iowa Women of Innovation Award, 2010. Editorial Board, Organic Reactions, 2010-2011. Horace S. Isbell Award, Division of Carbohydrate Chemistry, American Chemical

Society, 2010. Elected to the Executive Committee (at Large) for the Division of Biological Chemistry,

American Chemical Society, 2010-2012. Elected as Member-at-Large for the Division of Carbohydrate Chemistry, American

Chemical Society, 2010-2012. Co-Vice Chair, Carbohydrates Gordon Research Conference, 2009. LAS Mid-Career Achievement in Research Award, Iowa State University, 2008. LAS Master Teacher Award, Iowa State University, 2008. Editorial Board Member, Chemistry Central Journal, 2007-present. Editorial Advisory Board, Carbohydrate Research, 2007-2012. Co-Chair, NSF Workshop on Complexity and Emergent Phenomena, 2007. Golden Goggles Invitational Lecture, Middle Tennessee State University, 2007. Caldwell Chair of Chemistry, Iowa State University, 2006-2010. Alfred P. Sloan Foundation Research Fellow, 2005-2007. Robert O’Malley Visiting Scholar, Boston College, 2006. National Science Foundation CAREER Award, 2004-2009. Cottrell Scholar Award of Research Corporation, 2003-2008. NIH Postdoctoral Fellowship, 1998-2000. Christine Kohler Fellowship, 1994-1997.

Department of Education Fellowship, 1993-1994. Harvard College Scholarship, 1987-1991. J. S. Sirrine Scholarship, 1987-1991. Robert C. Byrd Scholarship, 1987-1988. IV. INVITED PRESENTATIONS 2000 Natural Products Chemistry Gordon Research Conference, Plymouth, NH, 31 July. 2001 Truman State University, Department of Chemistry, Kirksville, MO, 2 November. 2003 Carbohydrates Gordon Research Conference, Tilton, NH, 24 June. University of Iowa, Department of Medicinal Chemistry, Iowa City, IA, 9 September. University of Toledo, Department of Chemistry, Toledo, OH, 22 September. St. Olaf’s College, Department of Chemistry, Northfield, MN, 9 October. 2004 Iowa State University, Analytical chemistry seminar series, Ames, IA, 30 January. University of Nebraska at Lincoln, Department of Chemistry, Lincoln, NE, 16 February.


Clemson University, Department of Chemistry, Clemson, SC, 8 April. NSF Workshop on Organic Synthesis and Natural Products, Squam Lake, NH, 11 June. Bioorganic Gordon Research Conference, Andover, NH, 15 June. University of Alberta, Department of Chemistry, Edmonton, AB (Canada), 12 August. Emory University, Department of Chemistry, Atlanta, GA, 29 September. West Virginia University, Department of Chemistry, Morgantown, WV, 13 October. University of Pittsburgh, Department of Chemistry, Pittsburgh, PA, 14 October. Boston University, Department of Chemistry, Boston, MA, 25 October. University of Calgary, Department of Biochemistry and Molecular Biology, Calgary, AB

(Canada), 5 November. Princeton University, Department of Chemistry, Princeton, NJ, 22 November. Iowa State University, Department of Biochemistry, Biophysics, and Molecular Biology, Ames,

IA, 2 December. University of Illinois at Urbana-Champaign, Department of Chemistry, Urbana, IL, 9 December. 2005 University of California at Irvine, Department of Molecular Biology and Biochemistry, Irvine,

CA, 7 January. Northwestern University, Department of Chemistry, Evanston, IL, 20 January. University of Washington, Department of Chemistry, Seattle, WA, 28 January. University of North Carolina, Department of Chemistry, Chapel Hill, NC, 11 February. Biophysical Society National Meeting, Long Beach, CA, 13 February. Duke University, Department of Chemistry, Durham, NC, 15 February. University of Arkansas, Department of Chemistry, Fayetteville, AR, 28 February. Iowa State University College of Veterinary Medicine, Department of Biomedical Sciences,

Ames, IA, 9 March. American Chemical Society National Meeting, Hudson Award Symposium, San Diego, CA, 14

March. Michigan Technological University, Department of Chemistry, Houghton, MI, 8 April. National Institutes of Health (NIH), Laboratory of Experimental and Computational Biology,

National Cancer Institute, Frederick, MD, 22 April. Iowa State University, Biorenewable Resources and Technology seminar series, Ames, IA, 26

April. Carbohydrate Symposium, Alberta Ingenuity Centre for Carbohydrate Science, Lake Louis, AB

(Canada), 29 April. University of California at Los Angeles, Department of Chemistry and Biochemistry, Los

Angeles, CA, 5 May. Institut de Chimie des Substances Naturelles (ICSN), CNRS, Gif-sur-Yvette (France), 12 May. University of Berne, Department of Chemistry and Biochemistry, Berne (Switzerland), 31 May. F. Hoffmann-La Roche Ltd., Basel (Switzerland), 6 June. University of Konstanz, Department of Chemistry, Konstanz (Germany), 6 June. University of Milan, Department of Organic and Industrial Chemistry, Milan (Italy), 9 June. Carbohydrates Gordon Research Conference, Tilton, NH, 22 June. Iowa State University, REU in Computational Chemistry seminar series, Ames, IA, 28 June. Cottrell Scholars Conference, Research Corporation, Tuscon, AZ, 8 July. Natural Products Gordon Research Conference, Tilton, NH, 26 July.


American Chemical Society National Meeting, Fluorous Chemistry Symposium, Washington, DC, 29 August.

California Institute of Technology, Department of Chemistry, Pasadena, CA, 14 September. Georgia Institute of Technology, School of Chemistry and Biochemistry, Atlanta, GA, 27

September. University of California at Davis, Department of Chemistry, Davis, CA, 29 September. University of Wisconsin, Department of Chemistry, Madison, WI, 6 October. Edgewood College, Department of Natural Science, Madison, WI, 7 October. University of California at Los Angeles, California NanoSystems Institute (CNSI), Los Angeles,

CA, 11 October. Iowa State University, Organic/inorganic chemistry seminar series, 21 October. University of Rochester, Department of Chemistry, Rochester, NY, 28 October. University of Texas at Austin, College of Pharmacy, Medicinal Chemistry Program, Austin, TX,

3 November. Texas A&M University, Department of Chemistry, College Station, TX, 4 November. University of Oklahoma ACS PROGRESS Lecture, Department of Chemistry and Biochemistry,

Norman, OK, 14 November. Massachusetts Institute of Technology (MIT), Department of Chemistry, Cambridge, MA, 22

November. ArQule, Inc., Woburn, MA, 23 November. University of Georgia, Department of Chemistry, Athens, GA, 1 December. 8th Japanese-American Frontiers of Science Symposium, Shonan Village Center, Kanagawa

(Japan), 9-12 December. 2006 ACS-CSIR Indo-US Workshop on Organic Chemistry and Chemical Biology, Pune and

Hyderabad (India), 6-12 January. Creighton University, Department of Chemistry, Omaha, NE, 19 January. University of Michigan, Department of Biological Chemistry, Ann Arbor, MI, 31 January. University of California-Berkeley, Department of Chemistry, Berkeley, CA, 7 February. Louisiana State University, Department of Chemistry, Baton Rouge, LA, 17 February. Tulane University, Department of Chemistry, New Orleans, LA, 20 February. Iowa State University College of Veterinary Medicine, Departments of Veterinary Microbiology

and Pathology, Ames, IA, 28 February. Indianapolis University School of Medicine, Department of Biochemistry and Molecular Biology,

Indianapolis, IN, 6 March. 4th International Microwaves in Chemistry Conference, Orlando, FL, 8-11 March. Syracuse University, Life Sciences Retreat, Syracuse, NY, 14 March. American Chemical Society National Meeting, Carbohydrate Recognition Symposium, Atlanta,

GA, 27-28 March. Oberlin College, Department of Chemistry and Biochemistry, Oberlin, OH, 5 April. Vanderbilt University, Institute of Chemical Biology, Nashville, TN, 12 April. Brown University, Department of Chemistry, Providence, RI, 12 May. University of California at Santa Barbara, Department of Chemistry and Biochemistry, Santa

Barbara, CA, 16 May. University of California at San Francisco, Biophysics/Chemistry and Chemical Biology seminar

series, San Francisco, CA, 1 June.


XXIIIrd International Carbohydrate Symposium, Keynote Lecture, Whistler, BC (Canada), 23-28 July.

Society for Industrial Microbiology Annual Meeting, Emerging Areas and Systems in Biocatalysis session, Baltimore, MD, 2 August.

Iowa State University Molecular Parasitology Minisymposium, Ames, IA, 26 August. University of Northern Iowa, Department of Chemistry, Cedar Falls, IA, 31 August. American Chemical Society National Meeting, Carbohydrate Division Symposium, San

Francisco, CA, 11 September. Boston College, Robert O'Malley Visiting Scholar, Department of Chemistry, Chestnut Hill,

MA, 26 and 28 September. 2nd Annual Midwest Carbohydrate Symposium, Plenary Lecture, Wayne State University,

Detroit, MI, 30 September. University of California at Santa Barbara, Materials Research Laboratory, Santa Barbara, CA, 27

October. University of Nebraska at Lincoln, Department of Chemistry, Departmental Colloquium,

Lincoln, NE, 10 November. University of Colorado, Department of Chemistry and Biochemistry, Boulder, CO, 14

November. Society for Glycobiology National Meeting, Los Angeles, CA, 16 November. 2007 University of California at Los Angeles, Department of Chemistry and Biochemistry, Los

Angeles, CA, 12 January. Bachem Holding AG, Bubendorf (Switzerland), 24 January. ABC Technologies Conference, Plenary Lecture, Basel (Switzerland), 26 January. The College of St. Catherine, Department of Chemistry, St. Paul, MN, 23 February. Danforth Plant Sciences Center, St. Louis, MO, 14 March. American Chemical Society National Meeting, Francis P. Garvan-John M. Olin Award

Symposium, Chicago, IL, 28 March. Middle Tennessee State University, Golden Goggles Lecture, Department of Chemistry,

Murfreesboro, TN, 6 April. 5th International Microwaves in Chemistry Conference, Imperial College, London (UK), 19

April. 7th Carbohydrate Bioengineering Meeting, Keynote Lecture, Braunschweig (Germany), 23 April. Combinatorial Chemistry Gordon Research Conference, New London, NH, 3-8 June. Momenta Pharmaceuticals, Inc., Cambridge, MA, 22 June. International Symposium on Fluorous Technologies (ISoFT07), Plenary Lecture, Yokohama

(Japan), 31 July. The University of Tokyo, Graduate School of Pharmaceutical Sciences, Tokyo (Japan), 2 August. New York University, Department of Chemistry, New York, NY, 7 September. Auburn University, Department of Chemistry and Biochemistry, Auburn, AL, 20 September. University of Missouri-St. Louis, Department of Chemistry and Biochemistry, St. Louis, MO, 1

October. Kansas State University, Department of Biochemistry, Manhattan, KS, 10 October. University of California at Irvine, Department of Chemistry, Departmental Colloquium, Irvine,

CA, 2 November. Yale University, Department of Chemistry, New Haven, CT, 14 November.


Boehringer Ingelheim, Ridgefield, CT, 15 November. National Institutes of Health, Inter-Institute NIH Chemistry Seminar Series, Bethesda, MD, 14

December. 2008 Biochemistry Undergraduate Club, Iowa State University, Ames, IA, 23 January. University of Pennsylvania, Department of Chemistry, Philadelphia, PA, 28 January. Temple University, Department of Chemistry, Philadelphia, PA, 29 January. University of Minnesota, Department of Chemistry, Minneapolis, MN, 5 February. European Conference on Carbohydrates, Killarney (Ireland), 9-13 March. Winthrop University, Department of Chemistry, Physics, and Geology, Rock Hill, SC, 26 March. American Chemical Society National Meeting, ACS Award for Creative Work in Fluorine

Chemistry Award Symposium, New Orleans, LA, 7 April. State University of New York-ESF, Department of Chemistry, Syracuse, NY, 25 April. 6th International Microwaves in Chemistry Conference, Cambridge, MA, 14 May. Alnylam Pharmaceuticals, Inc., Cambridge, MA, 16 May. ZuChem, Inc., Chicago, IL, 9 June. Cottrell Scholars Conference, Research Corporation, Tuscon, AZ, 11 July. Iowa State University/University of Iowa Vaccine Meeting, Newton, IA, 20 August. University of Tennessee at Knoxville, Department of Chemistry, Knoxville, TN, 11 September. University of Missouri at Kansas City, Department of Chemistry, Kansas City, MO, 2 October. Iowa State University, Organic/inorganic chemistry seminar series, 10 October. Calvin College, Department of Chemistry and Biochemistry, Grand Rapids, MI, 23 October. Hope College, Department of Chemistry, Holland, MI, 24 October. 2009 19th Winter Fluorine Conference, St. Petersburg Beach, FL, 12 January. University of British Columbia, Lectures in Modern Chemistry series speaker, Vancouver, BC

(Canada), 20 January. Consortium for Functional Glycomics Workshop, La Jolla, CA, 15 March. 15 th European Carbohydrate Symposium, Plenary Lecture, Vienna (Austria), 24-29 July. 19th International Symposium on Fluorine Chemistry/ISoFT'09, Jackson Hole, WY, 24 August. Abo Akademi University, Department of Chemistry, Turku (Finland), 31 August. Finnish Glycoscience Graduate School, Island of Seili (Finland), 1 and 2 September. Iowa State University, Genetics, Developmental and Cell Biology seminar, 25 September. Midwest Regional American Chemical Society Meeting, Cope Scholar Synthesis Symposium,

Iowa City, IA, 23 October. University of Pennsylvania, Department of Chemistry, Philadelphia, PA, 13 November. Purdue University, Department of Chemistry, West Lafayette, IN, 17 November. 2010 Indiana University, Department of Chemistry, Bloomington, IN, 18 January. University of Iowa, Department of Chemistry, Iowa City, IA, 22 January. University of North Carolina at Charlotte, Department of Chemistry, Charlotte, NC, 8

February. President's Council, Iowa State University, Ames, IA, 5 March.


17th New Orleans Carbohydrate Symposium, New Orleans, LA, 26 March. Indiana University, Department of Biochemistry, Bloomington, IN, 14 May. American Chemical Society National Meeting, Wolfram/Isbell/New Investigator's Awards

Symposium, Boston, MA, 22 August. Iowa State University, Department of Chemical and Biological Engineering, 7 September. 4th Baltic Meeting on Microbial Carbohydrates, Hyytiälä Forestry Field Station (Finland), 20

September. Iowa State University Foundation Governors' Board Meeting, Ames, IA, 1 October. Truman State University, Department of Chemistry, Kirksville, MO, 8 October. The Pennsylvania State University, Department of Chemistry, University Park, PA, 8 November. Joint Southwest and Southeastern Regional ACS Meeting, New Orleans, LA, 3 December. 2011 Iowa Lieutenant Governor Campus Visit, Iowa State University, Ames, IA, 1 March. The Ohio State University, Departments of Chemistry and Biochemistry, Columbus, OH, 19

May. COBRE Retreat for University of Nebraska Medical Center, Nebraska City, NE, 1 June. Bioorganic Gordon Research Conference, Andover, NH, 13 June. BioMaP REU Program, Ames, IA, 19 July. CS3 Workshop, Beijing (China), 14 September. Watanabe Symposium in Chemical Biotechnology, Bloomington, IN, 15 October. Iowa State University, Department of Biochemistry, Biophysics, and Molecular Biology, Ames,

IA, 27 October. 2012 University of Georgia, Department of Chemistry, Athens, GA, February 16. Tufts University, Department of Chemistry, Medford, MA, 6 March. University of Delaware, Chemistry-Biology Interface Seminar Series, Newark DE, 7 March. American Chemical Society National Meeting, Gin Memorial Symposium, San Diego, CA, 29

March. University of Guelph, Biophysics Interdepartmental Group, Departments of Molecular and

Cellular Biology and of Chemistry, Guelph, Ontario (Canada), 15 May. Stereochemistry Gordon Research Conference, Newport, RI, 29 July-3 August. Denison University, Department of Chemistry and Biochemistry, Granville, OH, 13 November. 2013 11th Winter Conference on Medicinal and Bioorganic Chemistry, Steamboat Springs, CO, 22

January. University of Iowa, Department of Chemistry, Iowa City, IA, 15 February. NIH Workshop on Human Milk Oligosaccharides, Bethesda, MD, 22 February. Indianapolis University School of Medicine, Department of Biochemistry and Molecular Biology,

Indianapolis, IN, 25 February. American Chemical Society National Meeting, 60+ Years of Advances in Carbohydrate

Chemistry and Biochemistry: Symposium in Honor of Professor Derek Horton, New Orleans, LA, 9 April.

Carbohydrates Gordon Research Conference, West Dover, VT, 20 June.


University of Toronto, Department of Chemistry, Toronto, Ontario (Canada), 22 July. American Chemical Society National Meeting, Current Topics in Glycobiology, Indianapolis, IN,

8 September. American Chemical Society National Meeting, Entrepreneurial Interactive

Symposium/Workshop, Indianapolis, IN, 9 September. American Chemical Society National Meeting, Women in Innovation and Investing, Indianapolis,

IN, 10 September. University of Louisville, Department of Chemistry, Louisville, KY, 27 September. University of Pittsburgh, Department of Chemistry, Pittsburgh, PA, 24 October. 2014 American Chemical Society National Meeting, New Directions in Carbohydrate Synthesis,

Dallas, TX, 17 March. Oxford University, Chemical biology series, Oxford (England), 14 May. Westfälische-Wilhelms-Universität, Institute of Organic Chemistry, Münster (Germany), 21

May. University of Illinois at Chicago, Department of Chemistry, Chicago, IL, 27 May. 37th Steenbock Symposium: The Future of Chemical Biology, Madison, WI, 7 June. Accelerating Reaction Discovery Telluride Science Research Center Workshop, Telluride, CO,

29 July. ORCHEM, Weimar (Germany), 16 September. Philadelphia Organic Chemistry Club, Philadelphia, PA, 25 September. Southern Illinois University Edwardsville, Department of Chemistry, Edwardsville, IL, 6

October. University of Missouri-St. Louis, Department of Chemistry and Biochemistry, St. Louis, MO, 7

October. 2014 Joint Meeting of the Society for Glycobiology and the Japanese Society of Carbohydrate

Research, Honolulu, HI, 16 November. University of Notre Dame, Department of Chemistry and Biochemistry, Notre Dame, IN, 5

December. Rose-Hulman Institute of Technology, Department of Chemistry and Biochemistry, Terre

Haute, IN, 10 December. 2015 Center for Excellence for Women in Technology Salon, Bloomington, IN, 4 February. Indiana University Bloomington/Indiana University School of Medicine Chemical Biology Day,

Bradford Woods, IN, 13 February. FASEB Science Summer Conference “Origins and Benefits of Biologically Active Components in

Human Milk,” Big Sky, MT, 21 July. Enabling Technologies for Reactions and Processes Telluride Science Research Center

Workshop, Telluride, CO, 27 July. American Chemical Society National Meeting, Kavli Symposium, Boston, MA, 19 August. 21st International Symposium on Fluorine Chemistry/ISoFT'15, Como (Italy), 25 August. Oregon State University, Department of Chemistry, Corvallis, OR, 22 October. 2016


Mona Symposium: Natural Products and Medicinal Chemistry, Mona, Kingston (Jamaica), 6 January.

American Chemical Society National Meeting, Glycosylases: Inhibition and Therapeutic Applications Symposium, San Diego, CA, 14 March.

19th International Conference on Advancing the Chemical Sciences (ISACS19), Irvine, CA, 22 March.

Pfizer-MIT Lecture, Pfizer, Groton, CT, 4 May. Pfizer-MIT Lecture, Massachusetts Institute of Technology, Department of Chemistry,

Cambridge, MA, 5 May. Organic Reactions and Processes Gordon Research Conference, Easton, MA, 18 July. American Chemical Society Division of Organic Chemistry Graduate Research Symposium,

Bryn Mawr, PA, 29 July. Frontiers in Chemistry Colloquium, Wayne State University, Detroit, MI, 26 September. Midwest Carbohydrate and Glycobiology Symposium, Mount Pleasant, MI, 14 October. 2017 Vanderbilt University, Department of Chemistry Colloquium Series, Nashville, TN, 20 March. Old Dominion University, Department of Chemistry, Norfolk, VA, 30 March. American Chemical Society National Meeting, Hudson Award Symposium, San Francisco, CA, 3

April. Enabling Technologies for Reactions and Processes Telluride Science Research Center

Workshop, Telluride, CO, 20 June. Carbohydrates Gordon Research Conference, West Dover, VT, 25 June. International Symposium on Fluorous Technologies (ISoFT17), Award Lecture, Boston, MA, 10

August. United States Department of Agriculture National Center for Agricultural Utilization Research,

Peoria, IL, 15 August. NIH Common Fund Glycoscience Program Participating Investigators Meeting Public Session,

Bethesda, MD, 30 August. Southwest Regional American Chemical Society Meeting, Lubbock, TX, 31 October. 2018 Radcliffe Institute for Advanced Study at Harvard Unviersity, Cambridge, MA, 24 January. Harvard University, Department of Chemistry and Chemical Biology, Cambridge, MA, 6

February. University of Connecticut, Department of Chemistry, Storrs, CT, 15 February. New England Science Writers, Cambridge, MA, 20 February. Northeastern University, Department of Chemistry and Chemical Biology, Boston, MA, 28

February. Mosher Award Address, Silicon Valley Section of American Chemical Society, Santa Clara, CA,

15 March. American Chemical Society National Meeting, Wolfrom Award Address, New Orleans, LA, 18

March. American Chemical Society National Meeting, Recent Advances in Catalytic Carbohydrate

Reaction Development, New Orleans, LA, 20 March. Bowdoin College, Brunswick, ME, 16 April.


Massachusetts Institute of Technology, Department of Biochemistry, Cambridge, MA, 23 April. Boston College, Department of Chemistry, Chestnut Hill, MA, 16 May. Boston Glycobiology Discussion Group, Beth Israel Deaconess Medical Center, Boston, MA, 24

May. University of Canterbury, Department of Chemistry, Canterbury (New Zealand), 5 June. Victoria University and the Ferrier Institute, Kelburn (New Zealand), 6 June. Ferrier Lecture, Public lecture, Wellington (New Zealand), 6 June. University of Auckland, Department of Chemistry, Auckland (New Zealand), 8 June. NIH Common Fund Glycoscience Program Participating Investigators Meeting Public Session,

Bethesda, MD, 2 July. International Carbohydrate Symposium, Lisbon (Portugal), 18 July. International Symposium in Fluorine Chemistry, Oxford (UK), 23 July. V. PUBLICATIONS FROM GRADUATE AND POSTDOCTORAL WORK (* =

CORRESPONDING AUTHOR) 1) Manning, D. D.; Bertozzi, C. R.; Pohl, N. L.; Rosen, S. D.; Kiessling, L. L.* Selectin—

Saccharide Interactions: Revealing Structure—Function Relationships with Chemical Synthesis. J. Org. Chem. 1995, 60, 6254-6255.

2) Kiessling, L. L.*; Pohl, N. L. Strength in numbers:non-natural polyvalent carbohydrate

derivatives. Chem. Biol. 1996, 3, 71-77. (invited review) 3) Pohl, N. L.; Kiessling, L. L.* Para-Chlorobenzyl Protecting Groups as Stabilizers of the

Glycosidic Linkage: Synthesis of the 3'-O-Sulfated Lewis X Trisaccharide. Tetrahedron Lett. 1997, 38, 6985-6988.

4) Pohl, N. L.; Gokhale, R. S.; Cane, D. E.; Khosla, C.* Synthesis and Incorporation of an N-

Acetylcysteamine Analogue of Methylmalonyl-CoA by a Modular Polyketide Synthase. J. Am. Chem. Soc. 1998, 120, 11206-11207.

5) Richardson, M. T.; Pohl, N. L.; Kealey, J. T.; Khosla, C.* Tolerance and Specificity of

Recombinant 6-Methylsalicylic Acid Synthase. Metabolic Engineering 1999, 1, 180-187. 6) Pohl, N. L.; Kiessling, L. L.* Scope of Multivalent Ligand Function: Lactose-Bearing

Neoglycopolymers By Ring-Opening Metathesis Polymerization. Synthesis, 1999, 1515-1519.

7) Marti, T.; Hu, Z.; Pohl, N.; Shah, A.; Khosla, C.* Cloning, Nucleotide Sequence, and

Heterologous Expression of the Biosynthetic Gene Cluster for R1128, a Non-Steroidal Estrogen Receptor Antagonist. Insights into an Unusual Priming Mechanism. J. Biol. Chem. 2000, 275, 33443-33448.

8) Pohl, N. L.; Hans, M.; Lee, H. Y.; Kim, Y. S.; Cane, D. E.; Khosla, C.* Remarkably Broad

Substrate Tolerance of Malonyl-CoA Synthetase, an Enzyme Capable of Intracellular Synthesis of Polyketide Precursors. J. Am. Chem. Soc. 2001, 123, 5822-5823.


VI. PUBLICATIONS FROM INDEPENDENT CAREER (* = CORRESPONDING AUTHOR) 1) Pohl, N. L.* Developing New Antibiotics With Combinatorial Biosynthesis. J. Chem. Educ.

2000, 77, 1421-1423. (invited review) 2) Pohl, N.*; Clague. A.; Schwarz, K. Chiral Compounds and Green Chemistry in

Undergraduate Organic Laboratories: Reduction of a Ketone By Sodium Borohydride And Baker’s Yeast. J. Chem. Educ. 2002, 79, 727-728.

3) Pohl, N. L.* Nonnatural Substrates for Polyketide Synthases and their Associated

Modifying Enzymes. Curr. Opin. Chem. Biol. 2002, 6, 773-778. (invited review) 4) Ko, K.-S.; Kruse, J.; Pohl, N. L.* Synthesis of Isobutyl-C-galactoside (IBCG) as an

Isopropylthiogalactoside (IPTG) Substitute for Increased Induction of Protein Expression. Org. Lett. 2003, 5, 1781-1783.

5) Jaipuri, F. A.; Bower, B. D.; Pohl, N. L.* Protic Acid-Catalyzed Polymerization of b-

Lactones for the Synthesis of Chiral Polyesters. Tetrahedron: Asymmetry 2003, 14, 3249-3252.

6) Zea, C. J.; MacDonell, S. W.; Pohl, N. L.* Discovery of the Archaeal Chemical Link

Between Glycogen (Starch) Synthase Families Using a New Mass Spectrometry Assay. J. Am. Chem. Soc. 2003, 125, 13666-13667.

7) Zea, C. J.; Pohl, N. L.* Kinetic and Substrate Binding Analysis of Phosphorylase b Via

Electrospray Ionization Mass Spectrometry: A Model for Chemical Proteomics of Sugar Phosphorylases. Anal. Biochem. 2004, 327, 107-113.

8) Jaipuri, F. A.; Jofre, M. F.; Schwarz, K.; Pohl, N. L.* Microwave-assisted cleavage of

Weinreb amide for carboxylate protection in the synthesis of a (R)-3-hydroxyalkanoic acid. Tetrahedron Lett. 2004, 45, 4149-4152.

9) Zea, C. J.; Pohl, N. L.* General Assay for Sugar Nucleotidyltransferases Using

Electrospray Ionization Mass Spectrometry. Anal. Biochem. 2004, 328, 196-202. 10) Yu, Y.; Ko, K.-S.; Zea, C. J.; Pohl, N. L.* Discovery of the Chemical Function of

Glycosidases: Design, Synthesis, and Evaluation of Mass-differentiated Carbohydrate Libraries. Org. Lett. 2004, 6, 2031-2033.

11) Ko, K.-S.; Zea, C. J.; Pohl, N. L.* Surprising Bacterial Nucleotidyltransferase Selectivity in

the Conversion of Carbaglucose-1-phosphate. J. Am. Chem. Soc. 2004, 126, 13188-13189.

12) Mizanur, R. M.; Zea, C. J.; Pohl, N. L.* Unusually Broad Substrate Tolerance of a Heat-

Stable Archaeal Sugar Nucleotidyltransferase for the Synthesis of Sugar Nucleotides. J. Am. Chem. Soc. 2004, 126, 15993-15998.


13) Mizanur, R. M.; Jaipuri, F. A.; Pohl, N. L.* One-Step Synthesis of Labeled Sugar

Nucleotides for Protein O-GlcNAc Modification Studies by Chemical Function Analysis of an Archaeal Protein. J. Am. Chem. Soc. 2005, 127, 836-837.

14) Pohl, N. L.* Functional Proteomics for the Discovery of Carbohydrate-Related Enzyme

Activities. Curr. Opin. Chem. Biol. 2005, 9, 76-81. (invited review) 15) Ko, K.-S.; Zea, C. J.; Pohl, N. L.* Strategies for the Chemoenzymatic Synthesis of

Deoxysugar Nucleotides: Substrate Binding Versus Catalysis. J. Org. Chem. 2005, 70, 1919-1921.

16) Dutca, L.-M.; Ko, K.-S.; Pohl, N. L.; Kostic, N. M.* Platinum(II) Complex as an Artificial

Peptidase: Selective Cleavage of Peptides and a Protein by cis-[Pt(en)(H2O)2]2+ Ion under Different Irradiations. Inorg. Chem. 2005, 44, 5141-5146.

17) Zea, C. J.; Pohl, N. L.* Unusual Sugar Nucleotide Recognition Elements of Mesophilic

Versus Thermophilic Glycogen Synthases. Biopolymers, 2005, 79, 106-113. 18) Ko, K.-S.; Jaipuri, F. A.; Pohl, N. L.* Fluorous-Based Carbohydrate Microarrays. J. Am.

Chem. Soc. 2005, 127, 13162-13163. 19) Choi, D. W.; Zea, C. J; Do, Y. S.; Semrau, J. D.; Antholine, W. E.; Hargrove, M. S.; Pohl,

N. L.; Boyd, E. S.; Geesey, G. G.; Hartsel, S. C.; Shafe, P. H.; McEllistrem, M. T.; Kisting, C. J.; Campbell, D.; Rao, V.; de la Mora, A. M.; DiSpirito, A. A.* Spectral, Kinetic, and Thermodynamic Properties of Cu(I)- and Cu(II)-binding by Methanobactin from Methylosinus trichosporium OB3b, Biochemistry, 2006, 45, 1442-1453.

20) Wacker, M.; Feldman, M. F.; Callewaert, N.; Kowarik, M.; Clarke, B. R.; Pohl, N. L.;

Hernandez, M.; Vines, E. D.; Valvano, M. A.; Whitfield, C.; Aebi, M.* Substrate Specificity of Bacterial Oligosaccharyltransferase Suggests a Common Transfer Mechanism for the Bacterial and Eukaryotic Systems, Proc. Natl Acad. Sci., USA, 2006, 103, 7088-7093.

21) Mamidyala, S. K.; Ko, K.-S.; Jaipuri, F. A.; Park, G.; Pohl, N. L.* Noncovalent Fluorous

Interactions for the Synthesis of Carbohydrate Microarrays. J. Fluorine Chem. 2006, 127, 571-579. (special issue)

22) Choi, D. W.; Do, Y. S.; Zea, C. J.; McEllistrem, M. T.; Lee, S.-W.; Semrau, J. D.; Pohl, N.

L.; Kisting, C. J.; Scardino, L. L.; Hartsel, S. C.; Boyd, E. S.; Gessey, G. G.; Riedel, T. P.; Shafe, P. H.; Kranski, K. A.; Tritsch, J. R.; Antholine, W. W.; DiSpirito, A. A.* Spectral and Thermodynamic Properties of Ag(I), Au(III), Cd(II), Co(II), Fe(III), Hg(II), Mn(II), Ni(II), Pb(II), U(IV), and Zn(II) Binding by Methanobactin from Methylosinus trichosporium OB3b. J. Inorg. Biochem. 2006, 100, 2150-2161. (special issue)

23) Pohl, N. L.* Carbohydrate Microarrays and Fluorous-Phase Synthesis: Interfacing

Fluorous-Phase Tags with the Direct Formation of Glycoarrays. In Current Fluoroorganic


Chemistry: New Synthetic Directions, Technologies, Materials, and Biological Applications; Soloshonok, V. A.; Mikami, K.; Yamazaki, T.; Welch, J. T.; Honek, J. F., Eds. ACS Symposium Series 949; American Chemical Society: Washington, DC, 2007, pp. 261-270. (invited book chapter)

24) Mizanur, R. M.; Pohl, N. L.* Cloning and characterization of a heat-stable CMP-N-

acylneuraminic acid synthetase from Clostridium thermocellum. Appl. Microbiol. Biotechnol. 2007, 76, 827-834.

25) Mizanur, R. M.; Griffin, A. K. K.; Pohl, N. L.* Recombinant production and biochemical

characterization of a hyperthermostable a-glucan/maltodextrin phosphorylase from Pyrococcus furiosus. Archaea, 2007, 2, 169-176.

26) Pohl, N. L.* Automated Solution-Phase Oligosaccharide Synthesis and Carbohydrate

Microarrays: Development of Fluorous-Based Tools for Glycomics. In Chemical Glycobiology; Chen, X.; Halcomb, R.; Wang, G. P., Eds. ACS Symposium Series 990; American Chemical Society: Washington, DC, 2008, pp. 272-287. (invited book chapter)

27) Yu, Y.; Mizanur, R. M.; Pohl, N. L.* Glycosidase activity profiling for bacterial identification

by a chemical proteomics approach. Biocatal. Biotransform. 2008, 26, 25-31. (special issue)

28) Mizanur, R. M.; Pohl, N. L.* A thermostable promiscuous glucose-1-phosphate

uridyltransferase from Helicobacter pylori for the synthesis of nucleotide sugars. J. Mol. Catal. B: Enzymatic. 2008, 50, 13-19.

29) Jaipuri, F. A.; Collet, B. Y. M.; Pohl, N. L.* Synthesis and Quantitative Evaluation of Glycero-

D-manno-heptose Binding to Concanavalin A by Fluorous-tag Assistance. Angew. Chem. Int. Ed. 2008, 47, 1707-1710.

30) Pohl, N.*; Schwarz, K. Polymer-Supported Reagents and 1H-19F NMR Couplings: The

Synthesis of 2-Fluoroacetophenone. J. Chem. Educ. 2008, 85, 834-835. 31) Chen, G.-S.; Pohl, N. L.* Synthesis of Fluorous Tags for Incorporation of Reducing Sugars

into a Quantitative Microarray Platform. Org. Lett. 2008, 10, 785-788. 32) Pohl, N. L.* Fluorous Tags Catching on Microarrays. Angew. Chem. Int. Ed. 2008, 47,

3868-3870. (invited review) 33) Jaipuri, F. A.; Pohl, N. L.* Toward Solution-Phase Automated Iterative Synthesis:

Fluorous-tag Assisted Solution-Phase Synthesis of Linear and Branched Mannose Oligomers, Org. Biomol. Chem. 2008, 6, 2686-2691.

34) Hui, Z.; Brokman, S.; Fang, N.; Pohl, N.; Yeung, E.* Linkage Position and Residue

Identification of Disaccharides by Tandem MS and Linear Discriminant Analysis, Rapid Commun. Mass Spectrom. 2008, 22, 1579-1586.


35) Park, G.; Ko, K.-S.; Zakharova, A.; Pohl, N. L.* Mono- Vs. Di-fluorous Tagged

Glucosamines for Iterative Oligosaccharide Synthesis. J. Fluorine Chem. 2008, 129, 978-982. (special issue)

36) Zea, C. J.; Camci-Unal, G.; Pohl, N. L.* Thermodynamics of Binding of Divalent

Magnesium and Manganese to Uridine Phosphates: Implications for Diabetes-Related Hypomagnesaemia and Carbohydrate Biocatalysis. Chem. Cent. J., 2008, 2, 15.

37) Mizanur, R. M.*; Pohl, N. L.* Bacterial CMP-Sialic Acid Synthetases: Production,

Properties and Applications. Appl. Microbiol. Biotechnol. 2008, 80, 757-765. (invited review)

38) Ko, K.-S.; Park, G.; Yu, Y.; Pohl, N. L.* Protecting Group-based Colorimetric Monitoring

of Fluorous-phase and Solid-phase Synthesis of Oligoglucosamines. Org. Lett. 2008, 10, 5381-5384.

39) Mizanur, R. M.; Pohl, N. L. B.* Phosphomannose isomerase/GDP-mannose

pyrophosphorylase from Pyrococcus furiosus: a thermostable biocatalyst for the synthesis of guanidinediphosphate-activated and mannose-containing sugar nucleotides. Org. Biomol. Chem. 2009, 7, 2135-2139.

40) Song, E.-H.; Pohl, N. L. B.* Fluorous-based small-molecule microarrays for protein,

antibody, and enzyme screening. Future Med. Chem. 2009, 1, 889-896. (invited special report)

41) Collet, B. Y. M.; Nagashima, T.; Yu, M. S.; Pohl, N. L. B.* Fluorous-based Peptide

Microarrays for Protease Screening. J. Fluorine Chem. 2009, 130, 1042-1048. 42) Song, E.-H.; Pohl, N. L. B.* Carbohydrate arrays: Recent developments in fabrication and

detection methods with applications. Curr. Opin. Chem. Biol. 2009, 13, 626-632. (invited review)

43) Camci-Unal, G.; Pohl, N. L. B.* Quantitative Determination of Heavy Metal Contaminant

Complexation by the Carbohydrate Polymer Chitin. J. Chem. Eng. Data, 2010, 55, 1117-1121.

44) Utku, Y.; Rohatgi, A.; Yoo, B.; Zuckermann, R. N.; Pohl, N. L.; Kirshenbaum, K.* Rapid

multistep synthesis of a bioactive peptidomimetic oligomer for the undergraduate lab. J. Chem. Educ. 2010, 87, 637-639.

45) Roychoudhury, R.; Pohl, N. L. B.* New Structures, Chemical Functions, and Inhibitors for

Glycosyltransferases. Curr. Opin. Chem. Biol. 2010, 14, 168-173. (invited review) 46) Camci-Unal, G.; Pohl, N. L. B.* Thermodynamics of binding interactions between divalent

copper and chitin fragments by isothermal titration calorimetry (ITC). Carbohydr. Polym. 2010, 81, 8-13.


47) Song, E.-H.; Osanya, A. O.; Petersen, C. A.; Pohl, N. L. B.* Synthesis of multivalent

tuberculosis and Leishmania-associated capping carbohydrates reveals structure-dependent responses allowing immune evasion. J. Am. Chem. Soc. 2010, 132, 11428-11430.

48) Choi, D. W.; Bandow, N. L.; McEllistrem, M. T.; Semrau, J. D.; Antholine, W. W.; Hartsel,

S. C.; Gallagher, W.; Zea, C. J.; Pohl, N. L.; Zahn, J. A.; DiSpirito, A. A.* Spectral and thermodynamic properties of methanobactin from gamme-proteobacterial methane oxidizing bacteria: A case for copper competition on a molecular level. J. Inorg. Biochem. 2010, 104, 1240-1247.

49) Pohl, N. L. B.*; Kirshenbaum, K.; Yoo, B.; Schulz, N.; Zea, C. J.; Streff, J. M.; Schwarz, K. L.

Student-driven design of peptide mimetics: microwave-assisted synthesis of peptoid oligomers. J. Chem. Educ. 2011, 88, 999-1001.

50) Lin, L.; Pohl, N. L. B.* A Fluorous Phosphate Protecting Group with Applications in

Carbohydrate Synthesis. Org. Lett. 2011, 13, 1824-1827. 51) Osanya, A.; Song, E.-H.; Metz, K.; Shimak, R. M.; Boggiatto, P. M.; Huffman, E.; Johnson, C.;

Hostetter, J. M.; Pohl, N. L. B.; Petersen, C. A.* Pathogen-derived oligosaccharides improve innate immune response to intracellular parasite infection. Am. J. Pathol. 2011, 179, 1329-1337.

52) Carrillo-Conde, B.; Song, E.-H.; Chavez-Santoscoy, A.; Phanse, Y.; Ramer-Tait, A. E.; Pohl,

N. L. B.; Wannemuehler, M. J.; Bellaire, B. H.; Narasimhan, B.* Mannose-Functionalized “Pathogen-Like” Polyanhydride Nanoparticles Target C-Type Lectin Receptors on Dendritic Cells. Mol. Pharmaceutics, 2011, 8, 1877-1886.

53) Nagappayya, S. K.; Pohl, N. L. B.* Production of Fluorous-Based Microarrays with

Uncharged Carbohydrates. In Carbohydrate Microarrays: Methods and Protocols. Methods in Molecular Biology, vol. 808, Chevolot, Y., Ed. Springer, 2011, 149-153. (invited book chapter)

54) Edwards, H. E.; Nagappayya, S. K.; Pohl, N. L. B.* Probing the Limitations of Fluorous

Content for Tag-Mediated Microarray Formation. Chem. Commun. 2012, 48, 510-512. 55) Lin, L.; Abdel Motaal, B.; Schmidt-Supprian, M.; Pohl, N. L. B.* Multigram Synthesis of

Isobutyl-beta-C-galactoside as a Substitute of Isopropylthiogalactoside for Exogenous Gene Induction in Mammalian Cells. J. Org. Chem. 2012, 77, 1539-1546.

56) Chavez-Santoscoy, A.; Roychoudhury, R.; Pohl, N. L. B.; Wannemuehler, M. J.;

Narasimhan, B.*; Ramer-Tait, A. E. Tailoring the Immune Response by Targeting C-type Lectin Receptors on Alveolar Macrophages Using “Pathogen-like” Amphiphilic Polyanhydride Nanoparticles. Biomaterials, 2012, 33, 4762-4772.


57) Camci-Unal, G.; Mizanur, R. M.; Pohl, N. L. B.* Synthesis of a 3-deoxy-D-manno-octulosonic acid (KDO) building block from D-glucose via fermentation. Org. Biomol. Chem. 2012, 10, 5856-5860. (special issue)

58) Pohl, N. L. B.*; Streff, J.; Brokman, S. Evaluating Sustainability: Soap versus Biodiesel

Production from Plant Oils. J. Chem. Educ. 2012, 89, 1053-1056.

59) Carillo-Conde, B. R.; Roychoudhury, R.; Chaves-Santoscoy, A. V.; Narasimhan, B.; Pohl, N. L. High-throughput synthesis of carbohydrates and functionalization of polyanhydride nanoparticles. J. Vis. Exp. 2012, 65, e3967.

60) Warner, C.; Camci-Unal, G.; Pohl, N. L. B.; Reilly, P.* Substrate Binding by the Catalytic Domain and Carbohydrate Binding Module of Ruminococcus flavefaciens FD-1 Xyloglucanase/Endoglucanase. Ind. Eng. Chem. Res. 2013, 52, 30-36. (special issue)

61) Lin, L.; Pohl, N. L. B.* Synthesis of a series of maltotriose phosphates with an evaluation

of the utility of a fluorous phosphate protecting group. Carbohydr. Res. 2013, 369, 14-24.

62) Roychoudhury, R.; Pohl, N. L. B.* Light fluorous-tag assisted synthesis of oligosaccharides. In Modern Synthetic Methods in Carbohydrate Chemistry—From Monosaccharides to Complex Glycoconjugates; Werz, D. B.; Vidal, S. Eds. Wiley-VCH, 2013, pp. 221-240, ISBN-10: 3527332847. (invited book chapter)

63) Phanse, Y.; Carrillo-Conde, B. R.; Ramer-Tait, A. E.; Roychoudhury, R.; Pohl, N. L. B.; Narasimhan, B.*; Wannemuehler, M. J.*; Bellaire, B. H.* Functionalization of polyanhydride microparticles with di-mannose influences uptake by and intracellular fate within dendritic cells. Acta Biomaterialia, 2013, 9, 8902-8909.

64) Ko, K.-S.; Mizanur, R. M.; Jackson, J. M.; Lin, L.; Pohl, N. L. B.* A mass-differentiated library strategy for identification of sugar nucleotidyltransferase activities from cell lysates. Anal. Biochem. 2013, 441, 8-12.

65) Goswami, M.; Ellern, A.; Pohl, N. L. B.* Bismuth(V)-mediated thioglycoside activation. Angew. Chem. Int. Ed. 2013, 52, 8441-8445.

66) Tsabedze, S. B.; Kabotso, D. E. K.; Pohl, N. L. B.* The development of N-aryl trifluoroacetimidate-based benzyl and allyl protecting group reagents. Tetrahedron Lett. 2013, 54, 6983-6985.

67) Slade, M. C.*, Raker, J.; Kobilka, B.; Pohl, N. L. B.* A Research Module for the Organic

Chemistry Laboratory: Multistep Synthesis of a Fluorous Dye Molecule. J. Chem. Educ. 2014, 91, 126-130.

68) Roychoudhury, R.; Pohl, N. L. B.* Synthesis of Fluorous Photolabile Aldehyde and

Carbamate and Alkyl Carbamate Protecting Groups for Carbohydrate-Associated Amines. Org. Lett. 2014, 16, 1156-1159.


69) Adams, J.°; Goswami, M.°; Pohl N.; Mallapragada, S. K.* Synthesis and Functionalization of

Virus-Mimicking Cationic Block Copolymers with Pathogen-Associated Carbohydrates as Potential Vaccine Adjuvants. RSC Advances, 2014, 4, 15655-15663. (°These two authors contributed equally to the work.)

70) Mukherjee, C.; Lin, L.; Pohl, N. L. B.* Regioselective Benzylation of 2-Deoxy-2-

Aminosugars Using Crown Ethers: Application to a Shortened Synthesis of Hyaluronic Acid Oligomers. Adv. Synth. Catal. 2014, 356, 2247-2256.

71) Vela Ramirez, J. E.; Roychoudhury, R.; Habte, H.; Cho, M. W.; Pohl, N. L. B.; Narasimhan,

B.* Carbohydrate-functionalized nanovaccines preserve HIV-1 antigen stability and activate antigen presenting cells. J. Biomater. Sci. Polym. Ed. 2014, 25, 1387-1406.

72) Goodman, J. T.; Vela Ramirez, J. E.; Boggiatto, P. M.; Roychoudhury, R.; Pohl, N. L. B.;

Wannemuehler, M. J.; Narasimhan, B.* Nanoparticle chemistry and functionalization differentially regulates dendritic cell-nanoparticle interactions and triggers dendritic cell maturation. Part. Part. Sys. Charact., 2014, 31, 1269-1280.

73) Mukherjee, C.; Shiao, T. C.; Pohl, N. L. B.* Facile access to (1→3)-glucosamine linkages:

Synthesis of Propyl 4,6-di-O-Benzyl-2-Deoxy-2-N-Trichloroacetyl-1-Thio-β-D-Glucopyranoside. Carbohydrate Chemistry: Proven Methods, Volume 3; 2015; Roy, R.; Vidal, S., Eds.; CRC Press, ISBN-10: 1466583576.

74) Vela Ramirez, J. E.; Goodman, J. T.; Boggiatto, P. M.; Roychoudhury, R.; Pohl, N. L. B.;

Hostetter, J. M.; Wannemuehler, M. J.; Narasimhan, B.* Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles. The AAPS Journal, 2015, 17, 256-267.

75) Nagy, G.; Pohl, N. L. B.* Complete Hexose Isomer Identification with Mass

Spectrometry. J. Am. Soc. Mass Spectrom. 2015, 26, 677-685. 76) Nagy, G.; Pohl, N. L. B.* Monosaccharide identification as a first step toward de novo

carbohydrate sequencing: Mass spectrometry strategy for the identification and differentiation of diastereomeric and enantiomeric pentose isomers. Anal. Chem. 2015, 87, 4566-4571.

77) Tang, S.-L.; Pohl, N. L. B.* Automated Solution-Phase Synthesis of β-1,4-Mannuronate and

β-1,4-Mannan. Org. Lett. 2015, 17, 2642-2645. 78) Roychoudhury, R.; Martinez, P.; Grinnage-Pulley, T.; Schaut, R. G.; Petersen, C. A.; Pohl,

N. L. B.* Acid-triggered degradable reagents for differentiation of adaptive and innate immune responses to Leishmania-associated carbohydrate. Angew. Chem. Int. Ed. 2015, 54, 9610-9613.


79) Tang, S.-L.; Linz, L.; Bonning, B.; Pohl, N. L. B.* Automated Solution-Phase Synthesis of Insect Glycans to Probe the Binding Affinity of Pea Enation Mosaic Virus. J. Org. Chem. 2015, 80, 10482-10489.

80) Pirinelli, A. L.; Trinidad, J.; Pohl, N. L. B.* Introducing Students to Protein Analysis

Techniques: Separation and Comparative Analysis of Gluten Proteins in Various Wheat Strains. J. Chem. Educ. 2016, 93, 330-334.

81) Gaye, M.*; Nagy, G.; Clemmer, D. E.; Pohl, N. L. B. Multidimensional Analysis of 16

Glucose Isomers by Ion Mobility Spectrometry. Anal. Chem. 2016, 88, 2335-2344. 82) Bhaduri, S.; Pohl, N. L. B.* Fluorous-Tag Assisted Syntheses of Sulfated Keratan Sulfate

Oligosaccharide Fragments. Org. Lett. 2016, 18, 1414-1417. 83) Tang, S.-L.; Pohl, N. L. B.* Automated Fluorous-Assisted Solution-Phase Synthesis of β-

1,2-, 1,3-, and 1,6-Mannan Oligomers. Carbohydr. Res. 2016, 430, 8-15. 84) Goswami, M.; Ashley, D.; Baik, M.-H.*; Pohl, N. L. B.* (*joint corresponding authors)

Mechanistic Studies of Bismuth(V)-Mediated Thioglycoside Activation Reveal Differential Reactivity of Anomers. J. Org. Chem. 2016, 81, 5949-5962.

85) Nagy, G.‡; Peng, T.‡; Pohl, N. L. B.* (‡joint first authors) General Label-Free Mass

Spectrometry-Based Assay To Identify Glycosidase Substrate Competence. Anal. Chem. 2016, 88, 7183-7190.

86) Saliba, R. C.*; Pohl, N. L. B.* (*joint corresponding authors) Designing sugar mimetics:

non-natural pyranosides as innovative chemical tools. Curr. Opin. Chem. Biol. 2016, 34, 127-134. (invited review)

87) Bode, L.*, Contractor, N.; Barile, D.; Pohl, N.; Prudden A. R., Boons, G.-J.; Jennewein, S.

Overcoming the limited availability of human milk oligosaccharides: challenges and opportunitites for research and application. Nutr. Rev. 2016, 74, 635-644. (review)

88) Nagy, G.‡; Peng, T.‡; Kabotso, D. E. K.; Novotny, M. V.; Pohl, N. L. B.* (‡joint first

authors) Protocol for the Purification of Protected Carbohydrates: Toward Coupling Automated Synthesis to Alternate-pump Recycling High-performance Liquid Chromatography. Chem. Commun. 2016, 52, 13253-13256.

89) Gaunitz, S.; Nagy, G.; Pohl, N. L. B.; Novotny, M. V.* Recent advances in the analysis of

complex glycoproteins. Anal. Chem. 2017, 89, 389-413. (invited review) 90) Nagy, G.‡; Peng, T.‡; Pohl, N. L. B.* (‡joint first authors) Recent liquid chromatographic

approaches and developments for the separation and purification of carbohydrates. Anal. Methods, 2017, 9, 3579-3593. (invited review)

91) Vickman, A.; Ashley, D.; Baik, M.-H.*; Pohl, N. L. B.* (*joint corresponding authors)

Effects of varying the 6-position oxidation state of hexopyranoses: a systematic


comparative computational analysis of 48 monosaccharide stereoisomers. J. Mol. Model. 2017, 23, 214.

92) Phanse, Y.; Carrillo-Conde, B. R.; Ramer-Tait, A. E.; Roychoudhury, R.; Broderick, S.;

Pohl, N. L. B.; Rajan, K.; Narasimhan, B.; Wannemuehler, M. J.; Bellaire, B. H.* Functionalization promotes pathogen-mimicking characteristics of polyanhydride nanoparticle adjuvants. J. Biomed. Mater. Res. Part A. 2017, DOI: 10.1002/jbm.a.36128.

93) Kabotso, D. E. K.; Pohl, N. L. B.* Pentavalent bismuth as a universal promoter for S-

containing glycosyl donors with a thiol additive. Org. Lett. 2017, 19, 4516-4519. 94) Peng, T.; Gabe, N.; Trinidad, J. C.; Jackson, J. M.; Pohl, N. L. B.* A high-throughput mass-

spectrometry-based assay for identiying the biochemical functions of putative glycosidases. ChemBioChem, 2017, 18, 2306-2311.

95) Grinnage-Pulley, T. L.*; Kabotso, D. E. K.; Rintelmann, C. L.; Roychoudhury, R.; Schaut, R.

G.; Toepp, A. J.; Gibson-Corley, K. N.; Parrish, M.; Pohl, N. L. B.; Petersen, C. A. Leishmania-derived trimannose modulates inflammatory response to significantly reduce Leishmania major-induced lesions. Infect. Immun. 2018, 86, e00672-17.

96) Saliba, R. C.; Wooke, Z. J.; Nieves, G. A.; Chu A.-H. A.; Bennett, C. S.*; Pohl, N. L. B.*

(*joint corresponding authors) Challenges in the conversion of manual processes to machine-assisted syntheses: Activation of thioglycosides donors with aryl(trifluoroethyl)iodonium triflimide. Org. Lett. 2018, 20, 800-803.

97) Peng, T.; Wooke, Z.; Pohl, N. L. B.* Scope and limitations of carbohydrate hydrolysis for

de novo glycan sequencing using a hydrogen peroxide/metallopeptide-based glycosidase mimic. Carbohydr. Res. 2018, 458/9, 85-88.

98) Marion, K. C; Wooke, Z.; Pohl, N. L. B.* Synthesis of protected glucose derivatives from

levoglucosan by development of common carbohydrate protecting group reactions under continuous flow conditions. Carbohydr. Res. 2018, in press. (special issue)

VII. BOOK REVIEWS AND COMMENTARIES 1) Pohl, N.* Cellular Addresses: Step One in Creating a Glycocode. Chem. Biol. 2004, 11,

891-892. (invited commentary) 2) Pohl, N.* Acyclic Peptide Inhibitors of Amylases. Chem. Biol. 2005, 12, 1257-1258.

(invited commentary) 3) Pohl, N. L.* Array methodology singles out pathogenic bacteria. Nature Chem. Biol. 2006,

2, 125-126. (invited commentary) 4) Pohl, N. L.* Building a Bridge to New Antibiotics. ACS Chem. Biol. 2006, 1, 14-16. (invited

commentary)


5) Pohl, N. L. B. The expanding world of glycobiology. Nature Chem. Biol. 2009, 5, 373

(invited book review) 6) Pohl, N.* The Sugar Code: Fundamentals of Glycosciences. ChemBioChem, 2010, 11,

1147. (invited book review) 7) Pohl, N. L. B.* Carbohydrate Chemistry: Proven Synthetic Methods. Carbohydr. Res.

2015, 412, 19. (invited book review) 8) Pohl, N. L. B.* Open Minds. Science, 2018, 360, 610. (book review) VIII. PUBLISHED PATENTS 1) Khosla, Chaitan; Lau, Janice; Pohl, Nicola L. Methods for making polyketides by

replacement of ketosynthase and aminotransferase domains in polyketide synthases. (Leland Stanford University, USA). PCT Int. Appl. (2000), 32 pp. Application: WO 99-US15047 19990702. Licensed to Kosan.

2) Pohl, Nicola L.; Ko, Kwang-Seuk. A More Stable Analog of Iso-Propylthiogalactoside for

Induction of Protein Expression. (Iowa State University Research Foundation, Inc, USA). PCT Int. Appl. (2004), 22 pp. Application: WO 2004-US12095 20041104.

3) Pohl, Nicola L.; Ko, Kwang-Seuk. Colorimetric monitoring of reactions in solution and

solid phase automated and manual systems. (Iowa State University Research Foundation, Inc, USA). U.S. (2010), 12 pp. Application: US 2006-403381 20060413. Patent No. US 7842511.

4) Pohl, Nicola L.; Park, Gisun. Automated solution-phase iterative synthesis of

biomoleculars and apparatus. (Iowa State University Research Foundation, Inc, USA). U.S. (2010), 17 pp. Application: Application: US 2007-767098 20070622. Patent No. US 20100159604.

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