NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O AIDS progression O Alcohol...

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NHGRI GWA Catalog www.genome.gov/GWAStudies Published Genome-Wide Associations through 12/2010, 1212 published GWA at p< 5x10 -8 for 210 traits

Transcript of NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O AIDS progression O Alcohol...

Page 1: NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O AIDS progression O Alcohol dependence Alopecia areata O Alzheimer disease O Amyloid A levels O Amyotrophic

NHGRI GWA Catalogwww.genome.gov/GWAStudies

Published Genome-Wide Associations through 12/2010, 1212 published GWA at p<5x10-8 for 210 traits

Page 2: NHGRI GWA Catalog hcorrada/CMSC858B/lectures/lect16/GWAS_2010_4.pdf · O AIDS progression O Alcohol dependence Alopecia areata O Alzheimer disease O Amyloid A levels O Amyotrophic

Examining the relative influence of familial, genetic, and ...hcorrada/CMSC858B/readings/bdes.pdf · risk models Héctor Corrada Bravoa,1, ... Sudha K. Iyengarc, and Grace Wahbad,1

Examining the relative influence of familial, genetic, and ...hcorrada/CMSC858B/readings/bdes.pdf · risk models Héctor Corrada Bravoa,1, ... Sudha K. Iyengarc, and Grace Wahbad,1

… · O O o o O o o o o O o o o o o O 0 o o o o o o o o O o o o o o O o o o o . o O o O o o o o O o O o o O o o o o o O O O o O O o o O o o o O o o o o

… · O O o o O o o o o O o o o o o O 0 o o o o o o o o O o o o o o O o o o o . o O o O o o o o O o O o o O o o o o o O O O o O O o o O o o o O o o o o

Chapter(03(–Linear(Regression( - UMIACSusers.umiacs.umd.edu/~hcorrada/IntroDataSci/lectures/Regression.pdf · Chapter(03(–Linear(Regression(Slides(by(ZiaKhan(Simple(Linear(Regression(0

Chapter(03(–Linear(Regression( - UMIACSusers.umiacs.umd.edu/~hcorrada/IntroDataSci/lectures/Regression.pdf · Chapter(03(–Linear(Regression(Slides(by(ZiaKhan(Simple(Linear(Regression(0

Lecture 2: Linear methods for regressionusers.umiacs.umd.edu/~hcorrada/PracticalML/pdf/lectures/...Lecture 2: Linear methods for regression Rafael A. Irizarry and Hector Corrada Bravo

Lecture 2: Linear methods for regressionusers.umiacs.umd.edu/~hcorrada/PracticalML/pdf/lectures/...Lecture 2: Linear methods for regression Rafael A. Irizarry and Hector Corrada Bravo

A statistical framework for modeling gene expression …hcorrada/CMSC858B/readings/svmIntegrate.pdf · A statistical framework for modeling gene expression using chromatin features

A statistical framework for modeling gene expression …hcorrada/CMSC858B/readings/svmIntegrate.pdf · A statistical framework for modeling gene expression using chromatin features

 · o o o O o O CJQ o O o o o o O o o O o o O o o o o O o o o O o o O o o O . o o o O o O to N o o o o O o o o O o o o o O o o o o o o O o o o o o o g

 · o o o O o O CJQ o O o o o o O o o O o o O o o o o O o o o O o o O o o O . o o o O o O to N o o o o O o o o O o o o o O o o o o o o O o o o o o o g

PATTERN’RECOGNITION’’ AND’MACHINE’LEARNING’cbcb.umd.edu/~hcorrada/PML/pdf/lectures/prml-slides-8.pdf · prml-slides-8.ppt Author: Hector Corrada Bravo Created Date: 11/26/2012

PATTERN’RECOGNITION’’ AND’MACHINE’LEARNING’cbcb.umd.edu/~hcorrada/PML/pdf/lectures/prml-slides-8.pdf · prml-slides-8.ppt Author: Hector Corrada Bravo Created Date: 11/26/2012

Take a read: mRNA abundance - University Of Marylandhcorrada/CMSC858B/lectures/lect12/RNAseqI.pdf · mRNA abundance estimation with RNAseq Hector Corrada Bravo CMSC858B Spring 2012

Take a read: mRNA abundance - University Of Marylandhcorrada/CMSC858B/lectures/lect12/RNAseqI.pdf · mRNA abundance estimation with RNAseq Hector Corrada Bravo CMSC858B Spring 2012

q-value - CBCBcbcb.umd.edu/~hcorrada/CFG/lectures/student_presentations/qvalue.pdf · set q-value cutoff at .05, and be sure that only 5% of the significant genes found are likely

q-value - CBCBcbcb.umd.edu/~hcorrada/CFG/lectures/student_presentations/qvalue.pdf · set q-value cutoff at .05, and be sure that only 5% of the significant genes found are likely

Gene Expression Analysis with R and Bioconductor: …cbcb.umd.edu/~hcorrada/CFG/lectures/lect21_bioc/bioconductor.pdf · Gene Expression Analysis with R and Bioconductor: from measurements

Gene Expression Analysis with R and Bioconductor: …cbcb.umd.edu/~hcorrada/CFG/lectures/lect21_bioc/bioconductor.pdf · Gene Expression Analysis with R and Bioconductor: from measurements

Gene expression analysis with R and Bioconductorusers.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21... · Gene expression analysis with R and Bioconductor: from measurements to annotated

Gene expression analysis with R and Bioconductorusers.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21... · Gene expression analysis with R and Bioconductor: from measurements to annotated

Stanford University · O o o o o o o O o o o o o o o o o o o o o O o o o O o o o o O O o O o o . o o o o o O o o o o o o O o o o O o n o O o o o o o o o o o O o o o O o

Stanford University · O o o o o o o O o o o o o o o o o o o o o O o o o O o o o o O O o O o o . o o o o o O o o o o o o O o o o O o n o O o o o o o o o o o O o o o O o

Analysis of Differential Gene Expression Studieshcorrada/CMSC858B/readings/Solutions_ch14.pdf · a case study of the estrogen data in Section 14.3.1. 14.2 Differential expression

Analysis of Differential Gene Expression Studieshcorrada/CMSC858B/readings/Solutions_ch14.pdf · a case study of the estrogen data in Section 14.3.1. 14.2 Differential expression

CMSC858B: Computational systems biology and functional ...users.umiacs.umd.edu/~hcorrada/CMSC858B/lectures/lect1/CMSC858P_Lecture1.pdfCMSC858B: Computational systems biology and functional

CMSC858B: Computational systems biology and functional ...users.umiacs.umd.edu/~hcorrada/CMSC858B/lectures/lect1/CMSC858P_Lecture1.pdfCMSC858B: Computational systems biology and functional

PATTERN’RECOGNITION’’ AND’MACHINE’LEARNING’users.umiacs.umd.edu/~hcorrada/PML/pdf/lectures/prml-slides-8.pdf · The(SumPProductAlgorithm((8)(To(compute(local(marginals:(•

PATTERN’RECOGNITION’’ AND’MACHINE’LEARNING’users.umiacs.umd.edu/~hcorrada/PML/pdf/lectures/prml-slides-8.pdf · The(SumPProductAlgorithm((8)(To(compute(local(marginals:(•

 · O O o o O o O O o O o O O o cn o O o O O O o O cn O o O o o O O O o o O . O O O o o O O 02 O O O o O O o O o O o O O o o O o O o O O o o o O O O o

 · O O o o O o O O o O o O O o cn o O o O O O o O cn O o O o o O O O o o O . O O O o o O O 02 O O O o O O o O o O o O O o o O o O o O O o o o O O O o

~0( UJ - CBCBcbcb.umd.edu/~hcorrada/CFG/lectures/lect7_DifferentialExpressionII/... · \L{(_oJ1 r-vrJ~ ~"J~ ~ \:)(\ ~0(./'(bJ ~J::: UJ II> A,) \.l~'~ vw \\ dt~-\-0S'--\-,U0 (r,~0)The

~0( UJ - CBCBcbcb.umd.edu/~hcorrada/CFG/lectures/lect7_DifferentialExpressionII/... · \L{(_oJ1 r-vrJ~ ~"J~ ~ \:)(\ ~0(./'(bJ ~J::: UJ II> A,) \.l~'~ vw \\ dt~-\-0S'--\-,U0 (r,~0)The

 · o o o 0 o o o o o o o o o o o o o o o o O o O o o o o o o o o o o o o o ... o o o bro o o o o o 0 o o o o o o o o o o O o o o o o o o o o o o o o o

 · o o o 0 o o o o o o o o o o o o o o o o O o O o o o o o o o o o o o o o ... o o o bro o o o o o 0 o o o o o o o o o o O o o o o o o o o o o o o o o

Cluster Analysis of Genomic Data - University Of Marylandcbcb.umd.edu/~hcorrada/CFG/readings/Solutions_ch13.pdf · Cluster Analysis of Genomic Data ... we generalize the output of

Cluster Analysis of Genomic Data - University Of Marylandcbcb.umd.edu/~hcorrada/CFG/readings/Solutions_ch13.pdf · Cluster Analysis of Genomic Data ... we generalize the output of

Gene Expression Analysis with R and Bioconductor: from ...users.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21_bioc/bioconductor.pdf · postulated that gene expression profiles of the

Gene Expression Analysis with R and Bioconductor: from ...users.umiacs.umd.edu/~hcorrada/CFG/lectures/lect21_bioc/bioconductor.pdf · postulated that gene expression profiles of the