New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2....
Transcript of New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2....
![Page 1: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/1.jpg)
Ecological Parasitology
Lab 2: Flagellates Spring 2011
![Page 2: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/2.jpg)
Flagellates
Classification Eukaryotes
Characteristics Flagellum (a) Binary Fission
![Page 3: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/3.jpg)
Flagellates
• Three main types – “Gut dwellers”- direct transmisison – “Blood dwellers”- indirect transmission via
vectors (anterior and posterior) – “Macrophage dwellers”- indirect
transmission via vectors
More specialized and harmful
![Page 4: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/4.jpg)
Gut Dwelling Flagellates
• Trichomonas vaginalis – No cysts – Causes vaginal
secretions and sterility if not treated
• Chilomastix mesnili – Cysts – Little harm mild
diarrhea
• Giardia lamblia – Common worldwide! – Cysts – Severe diarrhea,
chronic stomach problems
– Feeds on small intestinal villi
![Page 5: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/5.jpg)
Trichomonas spp. T. vaginalis
axostyle- supportive structure made of microtubules attached to base of flagella parabasal body- organelle at base of flagellum from which grows the axoneme, or “skeleton” of the flagellum costa- structure that extends along base of undulating membrane
![Page 6: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/6.jpg)
Chilomastix mesnili
blepharoplast- organelle at base of flagellum from which grows the axoneme, or “skeleton” of the flagellum cytostome- cell mouth
![Page 7: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/7.jpg)
Giardia lamblia
axoneme- “skeleton” of cilia and flagella. parabasal body- organelle at base of flagellum from which grows the axoneme
![Page 8: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/8.jpg)
Flagellates
• Three main types – “Gut dwellers”- direct transmisison – “Blood dwellers”- indirect transmission via
vectors (anterior and posterior) – “Macrophage dwellers”- indirect
transmission via vectors
More specialized and harmful
![Page 9: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/9.jpg)
Blood and Macrophage Dwelling Flagellates
• Phylum/subphylum/class Kinetoplasta – Giant mitochondria, called kinetoplast – Kinetosome at base of flagellum (simliar to
basal body)
trypomastigote promastigote epimastigote amastigote
kinetoplast kinetosome
![Page 10: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/10.jpg)
Blood Dwelling Flagellates
• Trypanosoma brucei (rhodesiense, gambiense) – African sleeping
sickness – Invades nervous and
lymphatic systems – Causes coma and
death Tsetse fly
kinetoplast
![Page 11: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/11.jpg)
Blood Dwelling Flagellates
• Trypanosoma cruzi – Chagas disease – Invades tissues like
heart, esophagus, colon, peripheral nervous system
Triatoma
amastigote trypomastigote
![Page 12: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/12.jpg)
Blood Dwelling Flagellates
• Trypanosoma equiperdum – Causes Dourine – Horses, donkeys – Sexually transmitted – No known vector – (slide with RBCs)
![Page 13: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/13.jpg)
Macrophage Dwelling Flagellates
• Leishmania donovani – “Kala azar”- visceral
leishmaniasis – Slow, torturous death
![Page 14: New Ecological Parasitology - University of Vermontaneal/ecoparasit/Flagellates2011.pdf · 2011. 2. 23. · Ecological Parasitology Lab 2: Flagellates Spring 2011 . Flagellates Classification](https://reader033.fdocuments.net/reader033/viewer/2022051916/60089a1c93198b5c752bdcad/html5/thumbnails/14.jpg)
Macrophage Dwelling Flagellates
• Leishmania tropica – Oriental sore-
cutaneous leishmaniasis
– Self-healing, but risk secondary infection